Hematopoietic stem cell gene regulation by GABP alpha/beta complex

No Pathway Network information available for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Pathways in the Hematopoietic stem cell gene regulation by GABP alpha/beta complex SuperPath

#	Name	Source	Genes
1	Hematopoietic stem cell gene regulation by GABP alpha/beta complex	WikiPathways	ADAMTSL4-AS1 ATM BCL2 BCL2L1 CREBBP DNMT1 DNMT3A DNMT3B EP300 ETV6 FLT3 FOXO3 GABPA GABPB1 GZMB PTEN SMAD4 SMARCA4 TERF2 ZFX (see all 20) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TERF2	Telomeric Repeat Binding Factor 2	Protein Coding	1
2	SMARCA4	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit ATPase 4	Protein Coding	1
3	BCL2L1	BCL2 Like 1	Protein Coding	1
4	BCL2	BCL2 Apoptosis Regulator	Protein Coding	1
5	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
6	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
7	SMAD4	SMAD Family Member 4	Protein Coding	1
8	GZMB	Granzyme B	Protein Coding	1
9	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	1
10	FOXO3	Forkhead Box O3	Protein Coding	1
11	ETV6	ETS Variant Transcription Factor 6	Protein Coding	1
12	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
13	DNMT3B	DNA Methyltransferase 3 Beta	Protein Coding	1
14	DNMT3A	DNA Methyltransferase 3 Alpha	Protein Coding	1
15	DNMT1	DNA Methyltransferase 1	Protein Coding	1
16	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
17	ZFX	Zinc Finger Protein X-Linked	Protein Coding	1
18	ADAMTSL4-AS1	ADAMTSL4 Antisense RNA 1	RNA Gene	1
19	GABPB1	GA Binding Protein Transcription Factor Subunit Beta 1	Protein Coding	1
20	GABPA	GA Binding Protein Transcription Factor Subunit Alpha	Protein Coding	1

Disorders associated with Hematopoietic stem cell gene regulation by GABP alpha/beta complex SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Diffuse large b-cell lymphoma	Enrichment	CREBBP, DNMT3A, ETV6, PTEN	7.88
2	Myeloma, multiple	Enrichment	ATM, CREBBP, DNMT3A, FLT3	5.92
3	Rare genetic intellectual disability	Enrichment	CREBBP, DNMT3A, EP300	5.91
4	Chronic myelomonocytic leukemia	Enrichment	ETV6, FLT3	4.91
5	Glioblastoma	Enrichment	ATM, DNMT3A	4.69
6	Leukemia, acute myeloid	Enrichment	DNMT3A, ETV6, FLT3	4.58
7	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	4.51
8	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	4.51
9	Gastric cancer	Enrichment	ATM, PTEN, SMAD4	4.49
10	Inherited cancer-predisposing syndrome	Enrichment	ATM, PTEN, SMAD4, SMARCA4	4.43
11	Melanoma	Enrichment	DNMT3A, PTEN	4.03
12	Leukemia, acute lymphoblastic	Enrichment	ETV6, FLT3	3.95
13	Uterine corpus cancer	Enrichment	ATM, PTEN	3.95
14	Gliosarcoma	Enrichment	ATM, DNMT3A	3.61
15	Colorectal cancer	Enrichment	ATM, EP300, SMAD4	3.57
16	Giant cell glioblastoma	Enrichment	ATM, DNMT3A	3.56
17	Endometrial cancer	Enrichment	ATM, PTEN	3.37
18	Congenital nervous system abnormality	Enrichment	CREBBP, DNMT3A, PTEN	3.32
19	Nervous system disease	Enrichment	CREBBP, DNMT3A, PTEN	3.32
20	Pancreatic cancer	Enrichment	ATM, SMAD4	3.22
21	Bladder cancer	Enrichment	ATM, PTEN	3.09
22	Prostate cancer	Enrichment	ATM, PTEN	3.09
23	Vacterl association with hydrocephalus	Enrichment	PTEN	2.83
24	Intellectual developmental disorder, x-linked, syndromic 37	Enrichment	ZFX	2.83
25	Heyn-sproul-jackson syndrome	Enrichment	DNMT3A	2.83
26	Papillary tumor of the pineal region	Enrichment	PTEN	2.83
27	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	2.83
28	Endometrial serous adenocarcinoma	Enrichment	ATM	2.83
29	Glioma susceptibility 2	Enrichment	PTEN	2.83
30	Smarca4-deficient sarcoma of thorax	Enrichment	SMARCA4	2.83
31	Ovarian small cell carcinoma	Enrichment	SMARCA4	2.83
32	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.83
33	B-lymphoblastic leukemia/lymphoma with t(12;21)(p13.2;q22.1)	Enrichment	ETV6	2.83
34	Heritable thoracic aortic disease	Enrichment	SMAD4	2.83
35	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.83
36	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.83
37	Menke-hennekam syndrome	Enrichment	CREBBP	2.83
38	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.83
39	Hereditary breast carcinoma	Enrichment	ATM, PTEN	2.73
40	Thrombocytopenia	Enrichment	ETV6, SMAD4	2.65
41	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, PTEN	2.53
42	Myhre syndrome	Enrichment	SMAD4	2.53
43	Immunodeficiency-centromeric instability-facial anomalies syndrome 1	Enrichment	DNMT3B	2.53
44	Thumb deformity	Enrichment	CREBBP	2.53
45	Rhabdoid tumor predisposition syndrome 2	Enrichment	SMARCA4	2.53
46	Juvenile polyposis/hereditary hemorrhagic telangiectasia syndrome	Enrichment	SMAD4	2.53
47	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.53
48	Menke-hennekam syndrome 2	Enrichment	EP300	2.53
49	Intravascular large b-cell lymphoma	Enrichment	BCL2	2.53
50	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCA4	2.53
51	Facioscapulohumeral muscular dystrophy 4, digenic	Enrichment	DNMT3B	2.53
52	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.53
53	Cerebellar ataxia, deafness, and narcolepsy, autosomal dominant	Enrichment	DNMT1	2.53
54	Hematologic cancer	Enrichment	ETV6	2.53
55	Congenital mesoblastic nephroma	Enrichment	ETV6	2.53
56	High grade glioma	Enrichment	ATM	2.53
57	Otosclerosis 12	Enrichment	SMARCA4	2.53
58	Coffin-siris syndrome 4	Enrichment	SMARCA4	2.53
59	Tatton-brown-rahman syndrome	Enrichment	DNMT3A	2.53
60	Fibrosarcoma	Enrichment	ETV6	2.53
61	T-cell prolymphocytic leukemia	Enrichment	ATM	2.53
62	Acute myeloid leukemia without maturation	Enrichment	FLT3	2.53
63	Vacterl with hydrocephalus	Enrichment	PTEN	2.53
64	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	2.53
65	Juvenile polyposis of infancy	Enrichment	PTEN	2.53
66	Ataxia-telangiectasia	Enrichment	ATM	2.35
67	Juvenile polyposis syndrome	Enrichment	SMAD4	2.35
68	Polycythemia vera	Enrichment	ATM	2.35
69	Thrombocytopenia 5	Enrichment	ETV6	2.35
70	Neuropathy, hereditary sensory, type ie	Enrichment	DNMT1	2.35
71	Tethered spinal cord syndrome	Enrichment	CREBBP	2.35
72	Koolen-de vries syndrome	Enrichment	ATM	2.35
73	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL2	2.35
74	Adenocarcinoma	Enrichment	ATM	2.35
75	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	2.35
76	Laryngeal squamous cell carcinoma	Enrichment	PTEN	2.35
77	Mixed phenotype acute leukemia with t	Enrichment	FLT3	2.35
78	Breast cancer	Enrichment	ATM, PTEN	2.27
79	Mantle cell lymphoma	Enrichment	ATM	2.23
80	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3	2.23
81	Glioma	Enrichment	PTEN	2.23
82	Oculomotor apraxia	Enrichment	ATM	2.23
83	Macrocephaly/autism syndrome	Enrichment	PTEN	2.13
84	Rubinstein-taybi syndrome 2	Enrichment	EP300	2.13
85	Follicular lymphoma	Enrichment	BCL2	2.13
86	Acute myeloid leukemia with maturation	Enrichment	FLT3	2.13
87	Myeloproliferative neoplasm	Enrichment	DNMT3A	2.13
88	Hemangioma	Enrichment	PTEN	2.13
89	Acute megakaryocytic leukemia	Enrichment	PTEN	2.13
90	Autosomal thrombocytopenia with normal platelets	Enrichment	ETV6	2.13
91	Hemimegalencephaly	Enrichment	PTEN	2.13
92	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3	2.13
93	Primary hypereosinophilic syndrome	Enrichment	ETV6	2.13
94	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	SMAD4	2.13
95	Cowden syndrome 1	Enrichment	PTEN	2.05
96	Facioscapulohumeral muscular dystrophy 1	Enrichment	DNMT3B	2.05
97	Immunodeficiency-centromeric instability-facial anomalies syndrome	Enrichment	DNMT3B	2.05
98	Clear cell renal cell carcinoma	Enrichment	ATM	2.05
99	Hypertrichosis	Enrichment	CREBBP	2.05
100	Sporadic pheochromocytoma/secreting paraganglioma	Enrichment	DNMT3A	2.05
101	Ovarian cancer	Enrichment	ATM, PTEN	2.02
102	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.99
103	Squamous cell carcinoma, head and neck	Enrichment	PTEN	1.99
104	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.99
105	Hereditary sensory and autonomic neuropathy type 1	Enrichment	DNMT1	1.99
106	Gallbladder cancer	Enrichment	SMAD4	1.99
107	Hereditary hemorrhagic telangiectasia	Enrichment	SMAD4	1.99
108	Follicular thyroid carcinoma	Enrichment	PTEN	1.99
109	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.99
110	Autism spectrum disorder	Enrichment	DNMT3A, PTEN	1.96
111	Neuroblastoma	Enrichment	SMARCA4	1.93
112	Charge syndrome	Enrichment	EP300	1.88
113	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	FLT3	1.88
114	Ventricular septal defect	Enrichment	SMARCA4	1.88
115	Colonic benign neoplasm	Enrichment	ATM	1.88
116	Cowden syndrome	Enrichment	PTEN	1.88
117	Lynch syndrome 1	Enrichment	ATM	1.83
118	Leukemia, chronic lymphocytic	Enrichment	ATM	1.83
119	Immune deficiency disease	Enrichment	ATM	1.79
120	Meningioma, familial	Enrichment	PTEN	1.79
121	Atrial heart septal defect	Enrichment	SMARCA4	1.79
122	Interatrial communication	Enrichment	SMARCA4	1.79
123	Familial colorectal cancer type x	Enrichment	ATM	1.79
124	Specific learning disability	Enrichment	DNMT3A	1.79
125	Meningioma	Enrichment	PTEN	1.76
126	Hypercholesterolemia, familial, 1	Enrichment	SMARCA4	1.72
127	Breast-ovarian cancer, familial 1	Enrichment	ATM	1.72
128	Heart disease	Enrichment	CREBBP	1.69
129	Pituitary stalk interruption syndrome	Enrichment	DNMT1	1.69
130	Coffin-siris syndrome 1	Enrichment	SMARCA4	1.66
131	Renal cell carcinoma, nonpapillary	Enrichment	ATM	1.66
132	Polydactyly, postaxial, type a1	Enrichment	EP300	1.66
133	Corpus callosum, agenesis of	Enrichment	CREBBP	1.66
134	Familial hypercholesterolemia	Enrichment	SMARCA4	1.66
135	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.66
136	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.66
137	Hermansky-pudlak syndrome 1	Enrichment	ETV6	1.63
138	Rhabdomyosarcoma	Enrichment	PTEN	1.63
139	Cleft palate, isolated	Enrichment	SMARCA4	1.61
140	Precursor t-cell acute lymphoblastic leukemia	Enrichment	FLT3	1.48
141	Scoliosis	Enrichment	CREBBP	1.46
142	Differentiated thyroid carcinoma	Enrichment	ETV6	1.38
143	Cerebral palsy	Enrichment	SMARCA4	1.25
144	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD4	1.20
145	Body mass index quantitative trait locus 11	Enrichment	DNMT3A	1.15
146	Spastic ataxia	Enrichment	DNMT1	1.12
147	Autism	Enrichment	CREBBP	1.00
148	Microcephaly	Enrichment	EP300	0.78

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Pathway Network for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Member Pathways for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Pathways in the Hematopoietic stem cell gene regulation by GABP alpha/beta complex SuperPath

Associated Genes for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Associated Disorders for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Disorders associated with Hematopoietic stem cell gene regulation by GABP alpha/beta complex SuperPath

STRING Interaction Network for Hematopoietic stem cell gene regulation by GABP alpha/beta complex

Sources for Hematopoietic stem cell gene regulation by GABP alpha/beta complex