Hematopoietic Stem Cells and Lineage-specific Markers

No Pathway Network information available for Hematopoietic Stem Cells and Lineage-specific Markers

Pathways in the Hematopoietic Stem Cells and Lineage-specific Markers SuperPath

#	Name	Source	Genes
1	Hematopoietic Stem Cells and Lineage-specific Markers	R&D Systems	ADGRE1 ANGPTL5 ANPEP CCR1 CCR3 CCR7 CD14 CD163 CD164 CD19 CD1C CD2 CD209 CD22 CD226 CD244 CD28 CD33 CD34 CD36 CD38 CD3E CD4 CD44 CD48 CD5 CD59 CD68 CD69 CD79A CD79B CD80 CD83 CD86 CD8A CD96 CEACAM1 CEACAM3 CEACAM5 CEACAM6 CEACAM8 CSF1 CSF2 CSF3 CSF3R CX3CR1 ENG EPO FCER1A FCGR2A FLT3 FLT3LG GP1BA GP5 GYPA HLA-DRA IFNA2 IFNG IGFBP2 IL10 IL11 IL15 IL2 IL2RA IL2RB IL3 IL3RA IL4 IL5 IL6 IL7 IL7R ITGA2 ITGA2B ITGAL ITGAM ITGAV ITGAX ITGB3 KIT KITLG KLRB1 KLRC1 KLRC2 KLRF1 KLRK1 LAIR1 LAMP1 LY9 MME MPL MPO MS4A1 NCAM1 NCR1 NCR2 NCR3 NOTCH1 NOTCH2 NOTCH3 NOTCH4 PEAR1 PTGDR2 PTPRC SDC1 SELL SH2B3 SIGLEC7 SIGLEC8 SLAMF1 SPN THPO THY1 TIGIT TNF WNT3A (see all 116) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ANGPTL5	Angiopoietin Like 5	Protein Coding	1
2	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
3	FLT3LG	Fms Related Receptor Tyrosine Kinase 3 Ligand	Protein Coding	1
4	IGFBP2	Insulin Like Growth Factor Binding Protein 2	Protein Coding	1
5	IL3	Interleukin 3	Protein Coding	1
6	NOTCH1	Notch Receptor 1	Protein Coding	1
7	NOTCH2	Notch Receptor 2	Protein Coding	1
8	NOTCH3	Notch Receptor 3	Protein Coding	1
9	NOTCH4	Notch Receptor 4	Protein Coding	1
10	THPO	Thrombopoietin	Protein Coding	1
11	WNT3A	Wnt Family Member 3A	Protein Coding	1
12	IFNG	Interferon Gamma	Protein Coding	1
13	SH2B3	SH2B Adaptor Protein 3	Protein Coding	1
14	CD34	CD34 Molecule	Protein Coding	1
15	SPN	Sialophorin	Protein Coding	1
16	THY1	Thy-1 Cell Surface Antigen	Protein Coding	1
17	FLT3	Fms Related Receptor Tyrosine Kinase 3	Protein Coding	1
18	MME	Membrane Metalloendopeptidase	Protein Coding	1
19	CD38	CD38 Molecule	Protein Coding	1
20	SLAMF1	Signaling Lymphocytic Activation Molecule Family Member 1	Protein Coding	1
21	CD244	CD244 Molecule	Protein Coding	1
22	CD48	CD48 Molecule	Protein Coding	1
23	IL7	Interleukin 7	Protein Coding	1
24	IL7R	Interleukin 7 Receptor	Protein Coding	1
25	IL2	Interleukin 2	Protein Coding	1
26	CCR7	C-C Motif Chemokine Receptor 7	Protein Coding	1
27	CD2	CD2 Molecule	Protein Coding	1
28	LY9	Lymphocyte Antigen 9	Protein Coding	1
29	CD28	CD28 Molecule	Protein Coding	1
30	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	1
31	CD4	CD4 Molecule	Protein Coding	1
32	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	1
33	CD8A	CD8 Subunit Alpha	Protein Coding	1
34	CD96	CD96 Molecule	Protein Coding	1
35	CD226	CD226 Molecule	Protein Coding	1
36	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	1
37	SELL	Selectin L	Protein Coding	1
38	TIGIT	T Cell Immunoreceptor With Ig And ITIM Domains	Protein Coding	1
39	IL15	Interleukin 15	Protein Coding	1
40	KLRB1	Killer Cell Lectin Like Receptor B1	Protein Coding	1
41	FCGR2A	Fc Gamma Receptor IIa	Protein Coding	1
42	IL2RB	Interleukin 2 Receptor Subunit Beta	Protein Coding	1
43	ITGA2	Integrin Subunit Alpha 2	Protein Coding	1
44	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	1
45	KLRC1	Killer Cell Lectin Like Receptor C1	Protein Coding	1
46	KLRC2	Killer Cell Lectin Like Receptor C2	Protein Coding	1
47	KLRK1	Killer Cell Lectin Like Receptor K1	Protein Coding	1
48	NCR3	Natural Cytotoxicity Triggering Receptor 3	Protein Coding	1
49	NCR2	Natural Cytotoxicity Triggering Receptor 2	Protein Coding	1
50	NCR1	Natural Cytotoxicity Triggering Receptor 1	Protein Coding	1
51	KLRF1	Killer Cell Lectin Like Receptor F1	Protein Coding	1
52	SIGLEC7	Sialic Acid Binding Ig Like Lectin 7	Protein Coding	1
53	IL4	Interleukin 4	Protein Coding	1
54	CD19	CD19 Molecule	Protein Coding	1
55	CD5	CD5 Molecule	Protein Coding	1
56	CD79A	CD79a Molecule	Protein Coding	1
57	CD79B	CD79b Molecule	Protein Coding	1
58	MS4A1	Membrane Spanning 4-Domains A1	Protein Coding	1
59	CD22	CD22 Molecule	Protein Coding	1
60	SDC1	Syndecan 1	Protein Coding	1
61	CD80	CD80 Molecule	Protein Coding	1
62	CD86	CD86 Molecule	Protein Coding	1
63	ITGAX	Integrin Subunit Alpha X	Protein Coding	1
64	CD83	CD83 Molecule	Protein Coding	1
65	HLA-DRA	Major Histocompatibility Complex, Class II, DR Alpha	Protein Coding	1
66	IL3RA	Interleukin 3 Receptor Subunit Alpha	Protein Coding	1
67	CSF2	Colony Stimulating Factor 2	Protein Coding	1
68	CSF1	Colony Stimulating Factor 1	Protein Coding	1
69	TNF	Tumor Necrosis Factor	Protein Coding	1
70	CD14	CD14 Molecule	Protein Coding	1
71	CX3CR1	C-X3-C Motif Chemokine Receptor 1	Protein Coding	1
72	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
73	CD33	CD33 Molecule	Protein Coding	1
74	ANPEP	Alanyl Aminopeptidase, Membrane	Protein Coding	1
75	IFNA2	Interferon Alpha 2	Protein Coding	1
76	CD1C	CD1c Molecule	Protein Coding	1
77	CD209	CD209 Molecule	Protein Coding	1
78	IL6	Interleukin 6	Protein Coding	1
79	IL10	Interleukin 10	Protein Coding	1
80	CD163	CD163 Molecule	Protein Coding	1
81	CD36	CD36 Molecule (CD36 Blood Group)	Protein Coding	1
82	CD68	CD68 Molecule	Protein Coding	1
83	ENG	Endoglin	Protein Coding	1
84	ADGRE1	Adhesion G Protein-Coupled Receptor E1	Protein Coding	1
85	ITGAL	Integrin Subunit Alpha L	Protein Coding	1
86	CSF3	Colony Stimulating Factor 3	Protein Coding	1
87	KITLG	KIT Ligand	Protein Coding	1
88	CEACAM1	CEA Cell Adhesion Molecule 1	Protein Coding	1
89	CEACAM3	CEA Cell Adhesion Molecule 3	Protein Coding	1
90	CEACAM5	CEA Cell Adhesion Molecule 5	Protein Coding	1
91	CEACAM6	CEA Cell Adhesion Molecule 6	Protein Coding	1
92	CEACAM8	CEA Cell Adhesion Molecule 8	Protein Coding	1
93	CSF3R	Colony Stimulating Factor 3 Receptor	Protein Coding	1
94	MPO	Myeloperoxidase	Protein Coding	1
95	IL5	Interleukin 5	Protein Coding	1
96	CCR1	C-C Motif Chemokine Receptor 1	Protein Coding	1
97	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	1
98	CD44	CD44 Molecule (IN Blood Group)	Protein Coding	1
99	CD69	CD69 Molecule	Protein Coding	1
100	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	1
101	FCER1A	Fc Epsilon Receptor Ia	Protein Coding	1
102	LAIR1	Leukocyte Associated Immunoglobulin Like Receptor 1	Protein Coding	1
103	SIGLEC8	Sialic Acid Binding Ig Like Lectin 8	Protein Coding	1
104	CD164	CD164 Molecule	Protein Coding	1
105	LAMP1	Lysosomal Associated Membrane Protein 1	Protein Coding	1
106	EPO	Erythropoietin	Protein Coding	1
107	CD59	CD59 Molecule (CD59 Blood Group)	Protein Coding	1
108	GYPA	Glycophorin A (MNS Blood Group)	Protein Coding	1
109	GP1BA	Glycoprotein Ib Platelet Subunit Alpha	Protein Coding	1
110	GP5	Glycoprotein V Platelet	Protein Coding	1
111	ITGA2B	Integrin Subunit Alpha 2b	Protein Coding	1
112	ITGAV	Integrin Subunit Alpha V	Protein Coding	1
113	ITGB3	Integrin Subunit Beta 3	Protein Coding	1
114	MPL	MPL Proto-Oncogene, Thrombopoietin Receptor	Protein Coding	1
115	IL11	Interleukin 11	Protein Coding	1
116	PEAR1	Platelet Endothelial Aggregation Receptor 1	Protein Coding	1

Disorders associated with Hematopoietic Stem Cells and Lineage-specific Markers SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	GP1BA, ITGA2, ITGA2B, ITGB3	7.12
2	Human immunodeficiency virus type 1	Enrichment	CD209, CX3CR1, IFNG, IL10	4.85
3	Systemic lupus erythematosus	Enrichment	ENG, FCGR2A, IL10, ITGAM, TNF	4.72
4	Essential thrombocythemia	Enrichment	MPL, SH2B3, THPO	4.68
5	Malaria	Enrichment	CD36, FCGR2A, GYPA, TNF	4.40
6	Thrombocytopenia	Enrichment	GP1BA, ITGA2B, ITGB3, MPL, THPO	4.27
7	Autosomal dominant macrothrombocytopenia	Enrichment	GP1BA, ITGA2B, ITGB3	4.15
8	Immunodeficiency 104, severe combined	Enrichment	IL7R, PTPRC	4.14
9	Congenital amegakaryocytic thrombocytopenia	Enrichment	MPL, THPO	4.14
10	Bleeding disorder, platelet-type, 16	Enrichment	ITGA2B, ITGB3	3.66
11	Thrombocythemia 1	Enrichment	SH2B3, THPO	3.66
12	Dyskeratosis congenita, autosomal dominant 6	Enrichment	MPL, THPO	3.66
13	Migraine without aura	Enrichment	NOTCH3, TNF	3.66
14	Keratoacanthoma	Enrichment	NOTCH1, NOTCH2	3.66
15	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	FLT3, KIT	3.37
16	Cerebral malaria	Enrichment	CD36, TNF	3.37
17	Acute myeloid leukemia with maturation	Enrichment	FLT3, KIT	3.15
18	Vascular dementia	Enrichment	NOTCH3, TNF	3.15
19	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	FLT3, KIT	3.15
20	Testicular germ cell tumor	Enrichment	KIT, KITLG	2.97
21	Myelofibrosis	Enrichment	MPL, SH2B3	2.83
22	Glanzmann thrombasthenia 1	Enrichment	ITGA2B, ITGB3	2.83
23	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA, IL2RB	2.83
24	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA, IL2RB	2.83
25	Rheumatoid arthritis	Enrichment	CD244, IL10	2.60
26	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	CSF3R, FLT3	2.60
27	Cystic fibrosis	Enrichment	CEACAM3, CEACAM6, FCGR2A	2.60
28	Severe combined immunodeficiency	Enrichment	CD3E, IL7R, PTPRC	2.56
29	Autosomal non-syndromic agammaglobulinemia	Enrichment	CD79A, CD79B	2.51
30	Alzheimer's disease	Enrichment	MPO, TNF	2.27
31	Bernard-soulier syndrome, type a2, autosomal dominant	Enrichment	GP1BA	2.07
32	C syndrome	Enrichment	CD96	2.07
33	Type 1 diabetes mellitus 10	Enrichment	IL2RA	2.07
34	Systemic lupus erythematosus 6	Enrichment	ITGAM	2.07
35	Nonarteritic anterior ischemic optic neuropathy	Enrichment	GP1BA	2.07
36	Thrombocythemia 2	Enrichment	MPL	2.07
37	Coronary heart disease 7	Enrichment	CD36	2.07
38	Mastocytosis, cutaneous	Enrichment	KIT	2.07
39	Von willebrand disease, platelet-type	Enrichment	GP1BA	2.07
40	Hajdu-cheney syndrome	Enrichment	NOTCH2	2.07
41	Alagille syndrome 2	Enrichment	NOTCH2	2.07
42	Hyperpigmentation with or without hypopigmentation, familial progressive	Enrichment	KITLG	2.07
43	Lateral meningocele syndrome	Enrichment	NOTCH3	2.07
44	Amegakaryocytic thrombocytopenia, congenital, 1	Enrichment	MPL	2.07
45	Spinocerebellar ataxia 43	Enrichment	MME	2.07
46	Deafness, autosomal dominant 66	Enrichment	CD164	2.07
47	Immunodeficiency 116	Enrichment	CD8A	2.07
48	Microvascular complications of diabetes 2	Enrichment	EPO	2.07
49	Agammaglobulinemia 3, autosomal recessive	Enrichment	CD79A	2.07
50	Immunodeficiency 69	Enrichment	IFNG	2.07
51	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	2.07
52	Immunodeficiency 63 with lymphoproliferation and autoimmunity	Enrichment	IL2RB	2.07
53	Amegakaryocytic thrombocytopenia, congenital, 2	Enrichment	THPO	2.07
54	Fetomaternal alloimmune thrombocytopenia 2	Enrichment	ITGA2B	2.07
55	Okt4 epitope deficiency	Enrichment	CD4	2.07
56	Graft-versus-host disease	Enrichment	IL10	2.07
57	Immunodeficiency 18	Enrichment	CD3E	2.07
58	Skin/hair/eye pigmentation, variation in, 7	Enrichment	KITLG	2.07
59	Platelet glycoprotein iv deficiency	Enrichment	CD36	2.07
60	Malaria, mild	Enrichment	NCR3	2.07
61	Graham little-piccardi-lassueur syndrome	Enrichment	HLA-DRA	2.07
62	Hereditary thrombocytosis with transverse limb defect	Enrichment	THPO	2.07
63	Dengue virus	Enrichment	CD209	2.07
64	Myofibromatosis, infantile, 2	Enrichment	NOTCH3	2.07
65	Immunodeficiency, common variable, 3	Enrichment	CD19	2.07
66	Acute myeloid leukemia with minimal differentiation	Enrichment	FLT3	2.07
67	Hemolytic anemia, cd59-mediated, with or without immune-mediated polyneuropathy	Enrichment	CD59	2.07
68	Immunodeficiency 123 with hpv-related verrucosis	Enrichment	CD28	2.07
69	Immunodeficiency 105, severe combined	Enrichment	PTPRC	2.07
70	Macular degeneration, age-related, 12	Enrichment	CX3CR1	2.07
71	Immunodeficiency, common variable, 5	Enrichment	MS4A1	2.07
72	Erythrocytosis, familial, 5	Enrichment	EPO	2.07
73	Immunodeficiency 79	Enrichment	CD4	2.07
74	Cd45 deficiency	Enrichment	PTPRC	2.07
75	Chronic mast cell leukemia	Enrichment	KIT	2.07
76	Congenital membranous nephropathy due to maternal anti-neutral endopeptidase alloimmunization	Enrichment	MME	2.07
77	Deafness, autosomal dominant 69	Enrichment	KITLG	2.07
78	Thrombocytopenia 9	Enrichment	THPO	2.07
79	Immunodeficiency 125	Enrichment	FLT3LG	2.07
80	Bernard-soulier syndrome type a2	Enrichment	GP1BA	2.07
81	Charcot-marie-tooth disease type 2t	Enrichment	MME	2.07
82	Mme-related autosomal dominant charcot marie tooth disease type 2	Enrichment	MME	2.07
83	Transient cerebral ischemia	Enrichment	NOTCH3	2.07
84	Isolated bone marrow mastocytosis	Enrichment	KIT	2.07
85	Smoldering systemic mastocytosis	Enrichment	KIT	2.07
86	Fetomaternal alloimmune thrombocytopenia 3	Enrichment	ITGA2	2.07
87	Cerebral arteriopathy, autosomal recessive, with subcortical infarcts and leukoencephalopathy 1	Enrichment	NOTCH3	2.07
88	Immune dysregulation, neurodevelopmental defects, and colitis	Enrichment	ITGAV	2.07
89	Chronic neutrophilic leukemia	Enrichment	CSF3R	2.07
90	Agammaglobulinemia 3	Enrichment	CD79A	2.07
91	Mastocytosis	Enrichment	KIT	2.07
92	Familial progressive hyperpigmentation	Enrichment	KITLG	2.07
93	Growth retardation-mild developmental delay-chronic hepatitis syndrome	Enrichment	SH2B3	2.07
94	Cutaneous mastocytoma	Enrichment	KIT	2.07
95	Typical urticaria pigmentosa	Enrichment	KIT	2.07
96	T-b+ severe combined immunodeficiency due to il-7ralpha deficiency	Enrichment	IL7R	2.07
97	Nodular urticaria pigmentosa	Enrichment	KIT	2.07
98	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	2.07
99	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	2.07
100	Acute mast cell leukemia	Enrichment	KIT	2.07
101	Familial progressive hyper- and hypopigmentation	Enrichment	KITLG	2.07
102	Plaque-form urticaria pigmentosa	Enrichment	KIT	2.07
103	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	2.07
104	Testis seminoma	Enrichment	KIT	2.07
105	Arteriovenous malformations of the brain	Enrichment	ENG, IL6	1.95
106	Behcet syndrome	Enrichment	CCR1, IL10	1.95
107	Myeloma, multiple	Enrichment	FLT3, IL7R, SH2B3	1.92
108	Multisystem inflammatory syndrome in children	Enrichment	CD163, LY9	1.82
109	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.77
110	Pulmonary arteriovenous fistulas	Enrichment	ENG	1.77
111	Piebald trait	Enrichment	KIT	1.77
112	Agammaglobulinemia 6, autosomal recessive	Enrichment	CD79B	1.77
113	Neutrophilia, hereditary	Enrichment	CSF3R	1.77
114	Adams-oliver syndrome 5	Enrichment	NOTCH1	1.77
115	Neutropenia, severe congenital, 7, autosomal recessive	Enrichment	CSF3R	1.77
116	Waardenburg syndrome, type 2f	Enrichment	KITLG	1.77
117	Diamond-blackfan anemia-like	Enrichment	EPO	1.77
118	Infantile myofibromatosis	Enrichment	NOTCH3	1.77
119	Immunodeficiency 127	Enrichment	TNF	1.77
120	Agammaglobulinemia 6	Enrichment	CD79B	1.77
121	Lipodystrophy, familial partial, type 1	Enrichment	NOTCH3	1.77
122	Depressive disorder	Enrichment	NOTCH3	1.77
123	Severe congenital neutropenia 7	Enrichment	CSF3R	1.77
124	Multiple sclerosis 3	Enrichment	IL7R	1.77
125	Charcot-marie-tooth disease, axonal, type 2t	Enrichment	MME	1.77
126	Acute myeloid leukemia without maturation	Enrichment	FLT3	1.77
127	Common variable immunodeficiency phenotype due to cd19/cd81 deficiency	Enrichment	CD19	1.77
128	Mixed phenotype acute leukemia with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.77
129	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.77
130	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	1.59
131	Mycosis fungoides	Enrichment	CD28	1.59
132	Tuberous sclerosis 1	Enrichment	IFNG	1.59
133	Osteoporosis, juvenile	Enrichment	WNT3A	1.59
134	Psoriatic arthritis	Enrichment	TNF	1.59
135	Hepatitis c virus	Enrichment	IFNG	1.59
136	Tuberous sclerosis 2	Enrichment	IFNG	1.59
137	Testicular germ cell cancer	Enrichment	KIT	1.59
138	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	1.59
139	Mixed phenotype acute leukemia with t	Enrichment	FLT3	1.59
140	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD3E	1.59
141	Saczary syndrome	Enrichment	CD28	1.59
142	Kaposi sarcoma	Enrichment	IL6	1.47
143	Erythrocytosis, familial, 1	Enrichment	SH2B3	1.47
144	Myeloperoxidase deficiency	Enrichment	MPO	1.47
145	Chronic myelomonocytic leukemia	Enrichment	FLT3	1.47
146	Cerebrovascular disease	Enrichment	NOTCH3	1.47
147	Blood platelet disease	Enrichment	CD36	1.47
148	Inherited epidermodysplasia verruciformis	Enrichment	IL7	1.47
149	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	1.47
150	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.47
151	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	NOTCH3	1.38
152	Hydatidiform mole, recurrent, 1	Enrichment	NCR1	1.38
153	Bernard-soulier syndrome	Enrichment	GP1BA	1.38
154	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.38
155	Glanzmann thrombasthenia 2	Enrichment	ITGB3	1.38
156	Generalized juvenile polyposis/juvenile polyposis coli	Enrichment	ENG	1.38
157	Idiopathic aplastic anemia	Enrichment	IFNG	1.38
158	Familial cerebral saccular aneurysm	Enrichment	ENG	1.38
159	Leukemia, acute myeloid	Enrichment	FLT3, KIT	1.34
160	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	ENG	1.30
161	Type 1 diabetes mellitus	Enrichment	IL6	1.30
162	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.30
163	Autosomal dominant secondary polycythemia	Enrichment	EPO	1.30
164	Gastrointestinal stromal tumor	Enrichment	KIT	1.23
165	Waardenburg syndrome, type 2e	Enrichment	KITLG	1.23
166	Adams-oliver syndrome	Enrichment	NOTCH1	1.23
167	Alzheimer's disease 1	Enrichment	MPO	1.23
168	Hereditary hemorrhagic telangiectasia	Enrichment	ENG	1.23
169	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	FLT3	1.23
170	Severe congenital neutropenia	Enrichment	CSF3R	1.18
171	Hypoplastic left heart syndrome	Enrichment	NOTCH1	1.18
172	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	CD164, KITLG	1.14
173	Inflammatory bowel disease 1	Enrichment	IL6	1.13
174	Omenn syndrome	Enrichment	IL7R	1.08
175	Stroke, ischemic	Enrichment	NOTCH3	1.08
176	Aplastic anemia	Enrichment	IFNG	1.08
177	Migraine with or without aura 1	Enrichment	NOTCH3	1.04
178	Asthma	Enrichment	TNF	1.04
179	Leukemia, acute lymphoblastic	Enrichment	FLT3	1.04
180	Ichthyosis	Enrichment	IL2RB	1.04
181	Heritable pulmonary arterial hypertension	Enrichment	ENG	1.04
182	Lip and oral cavity carcinoma	Enrichment	KIT	1.01
183	Aortic valve disease 1	Enrichment	NOTCH1	0.98
184	Pulmonary hypertension, primary, 1	Enrichment	ENG	0.98
185	Aortic aneurysm, familial thoracic 1	Enrichment	NOTCH1	0.95
186	Breast cancer	Enrichment	IL2, IL7R	0.87
187	Alzheimer disease, familial, 1	Enrichment	MPO	0.87
188	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	MME	0.82
189	Diffuse large b-cell lymphoma	Enrichment	CD79B	0.82
190	Myocardial infarction	Enrichment	ITGB3	0.76
191	Precursor t-cell acute lymphoblastic leukemia	Enrichment	FLT3	0.75
192	Tetralogy of fallot	Enrichment	NOTCH1	0.70
193	Auditory neuropathy	Enrichment	NOTCH3	0.70
194	Severe covid-19	Enrichment	ITGAV	0.66
195	Connective tissue disease	Enrichment	NOTCH1	0.62
196	Peripheral nervous system disease	Enrichment	MME	0.62
197	Neuropathy	Enrichment	MME	0.62
198	Type 2 diabetes mellitus	Enrichment	IL6	0.52
199	Inherited cancer-predisposing syndrome	Enrichment	KIT, SH2B3	0.51
200	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	NOTCH1	0.50
201	Primary ovarian insufficiency	Enrichment	NOTCH2	0.40
202	Ovarian cancer	Enrichment	KIT	0.24

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Hematopoietic Stem Cells and Lineage-specific Markers

Pathway Network for Hematopoietic Stem Cells and Lineage-specific Markers

Member Pathways for Hematopoietic Stem Cells and Lineage-specific Markers

Pathways in the Hematopoietic Stem Cells and Lineage-specific Markers SuperPath

Associated Genes for Hematopoietic Stem Cells and Lineage-specific Markers

Associated Disorders for Hematopoietic Stem Cells and Lineage-specific Markers

Disorders associated with Hematopoietic Stem Cells and Lineage-specific Markers SuperPath

STRING Interaction Network for Hematopoietic Stem Cells and Lineage-specific Markers

Sources for Hematopoietic Stem Cells and Lineage-specific Markers