Hepatic ABC Transporters

No Pathway Network information available for Hepatic ABC Transporters

Pathways in the Hepatic ABC Transporters SuperPath

#	Name	Source	Genes
1	Hepatic ABC Transporters	QIAGEN	ABCB1 ABCB11 ABCB4 ABCC2 ATP1A1 ATP1A2 ATP1A3 ATP1A4 ATP1B1 ATP1B2 ATP1B3 ATP1B4 CLCA1 CLCA2 CLCA3P CLCA4 CLCN1 CLCN2 CLCN3 CLCN4 CLCN5 CLCN6 CLCN7 CLCNKA CLCNKB CLIC1 CLIC2 CLIC3 CLIC4 CLIC5 CLIC6 CLNS1A KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 SLC10A1 SLC4A3 SLCO1A2 SLCO1B1 SLCO4A1 (see all 73) (see less)
2	MODY (Maturity-Onset Diabetes of Young)	QIAGEN	CACNA1B CACNA1C CACNA1D CACNA1S FOXA2 GCK HNF1A HNF1B HNF4A IGF1R INS INSR KCMF1 KCNK1 KCNK10 KCNK12 KCNK13 KCNK15 KCNK16 KCNK17 KCNK2 KCNK3 KCNK4 KCNK5 KCNK6 KCNK7 KCNK9 KCNRG KCNT1 KCNT2 KCNU1 KCNV1 KCNV2 KCTD1 KCTD10 KCTD11 KCTD12 KCTD13 KCTD14 KCTD15 KCTD2 KCTD3 KCTD4 KCTD5 KCTD6 KCTD7 KCTD8 KCTD9 NEUROD1 PDX1 SLC2A2 (see all 51) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	KCMF1	Potassium Channel Modulatory Factor 1	Protein Coding	2
2	KCNK1	Potassium Two Pore Domain Channel Subfamily K Member 1	Protein Coding	2
3	KCNK10	Potassium Two Pore Domain Channel Subfamily K Member 10	Protein Coding	2
4	KCNK12	Potassium Two Pore Domain Channel Subfamily K Member 12	Protein Coding	2
5	KCNK13	Potassium Two Pore Domain Channel Subfamily K Member 13	Protein Coding	2
6	KCNK15	Potassium Two Pore Domain Channel Subfamily K Member 15	Protein Coding	2
7	KCNK16	Potassium Two Pore Domain Channel Subfamily K Member 16	Protein Coding	2
8	KCNK17	Potassium Two Pore Domain Channel Subfamily K Member 17	Protein Coding	2
9	KCNK2	Potassium Two Pore Domain Channel Subfamily K Member 2	Protein Coding	2
10	KCNK3	Potassium Two Pore Domain Channel Subfamily K Member 3	Protein Coding	2
11	KCNK4	Potassium Two Pore Domain Channel Subfamily K Member 4	Protein Coding	2
12	KCNK5	Potassium Two Pore Domain Channel Subfamily K Member 5	Protein Coding	2
13	KCNK6	Potassium Two Pore Domain Channel Subfamily K Member 6	Protein Coding	2
14	KCNK7	Potassium Two Pore Domain Channel Subfamily K Member 7	Protein Coding	2
15	KCNK9	Potassium Two Pore Domain Channel Subfamily K Member 9	Protein Coding	2
16	KCNRG	Potassium Channel Regulator	Protein Coding	2
17	KCNT1	Potassium Sodium-Activated Channel Subfamily T Member 1	Protein Coding	2
18	KCNU1	Potassium Calcium-Activated Channel Subfamily U Member 1	Protein Coding	2
19	KCNV1	Potassium Voltage-Gated Channel Modifier Subfamily V Member 1	Protein Coding	2
20	KCNV2	Potassium Voltage-Gated Channel Modifier Subfamily V Member 2	Protein Coding	2
21	KCTD1	Potassium Channel Tetramerization Domain Containing 1	Protein Coding	2
22	KCTD10	Potassium Channel Tetramerization Domain Containing 10	Protein Coding	2
23	KCTD11	Potassium Channel Tetramerization Domain Containing 11	Protein Coding	2
24	KCTD12	Potassium Channel Tetramerization Domain Containing 12	Protein Coding	2
25	KCTD13	Potassium Channel Tetramerization Domain Containing 13	Protein Coding	2
26	KCTD14	Potassium Channel Tetramerization Domain Containing 14	Protein Coding	2
27	KCTD15	Potassium Channel Tetramerization Domain Containing 15	Protein Coding	2
28	KCTD2	Potassium Channel Tetramerization Domain Containing 2	Protein Coding	2
29	KCTD3	Potassium Channel Tetramerization Domain Containing 3	Protein Coding	2
30	KCTD4	Potassium Channel Tetramerization Domain Containing 4	Protein Coding	2
31	KCTD5	Potassium Channel Tetramerization Domain Containing 5	Protein Coding	2
32	KCTD6	Potassium Channel Tetramerization Domain Containing 6	Protein Coding	2
33	KCTD7	Potassium Channel Tetramerization Domain Containing 7	Protein Coding	2
34	KCTD8	Potassium Channel Tetramerization Domain Containing 8	Protein Coding	2
35	KCTD9	Potassium Channel Tetramerization Domain Containing 9	Protein Coding	2
36	KCNT2	Potassium Sodium-Activated Channel Subfamily T Member 2	Protein Coding	2
37	ABCB1	ATP Binding Cassette Subfamily B Member 1	Protein Coding	1
38	ABCB11	ATP Binding Cassette Subfamily B Member 11	Protein Coding	1
39	ABCB4	ATP Binding Cassette Subfamily B Member 4	Protein Coding	1
40	ABCC2	ATP Binding Cassette Subfamily C Member 2	Protein Coding	1
41	ATP1A1	ATPase Na+/K+ Transporting Subunit Alpha 1	Protein Coding	1
42	ATP1A2	ATPase Na+/K+ Transporting Subunit Alpha 2	Protein Coding	1
43	ATP1A3	ATPase Na+/K+ Transporting Subunit Alpha 3	Protein Coding	1
44	ATP1A4	ATPase Na+/K+ Transporting Subunit Alpha 4	Protein Coding	1
45	ATP1B1	ATPase Na+/K+ Transporting Subunit Beta 1	Protein Coding	1
46	ATP1B2	ATPase Na+/K+ Transporting Subunit Beta 2	Protein Coding	1
47	ATP1B3	ATPase Na+/K+ Transporting Subunit Beta 3	Protein Coding	1
48	ATP1B4	ATPase Na+/K+ Transporting Family Member Beta 4	Protein Coding	1
49	CLCA1	Chloride Channel Accessory 1	Protein Coding	1
50	CLCA2	Chloride Channel Accessory 2	Protein Coding	1
51	CLCA3P	Chloride Channel Accessory 3, Pseudogene	Pseudogene	1
52	CLCA4	Chloride Channel Accessory 4	Protein Coding	1
53	CLCN1	Chloride Voltage-Gated Channel 1	Protein Coding	1
54	CLCN2	Chloride Voltage-Gated Channel 2	Protein Coding	1
55	CLCN3	Chloride Voltage-Gated Channel 3	Protein Coding	1
56	CLCN4	Chloride Voltage-Gated Channel 4	Protein Coding	1
57	CLCN5	Chloride Voltage-Gated Channel 5	Protein Coding	1
58	CLCN6	Chloride Voltage-Gated Channel 6	Protein Coding	1
59	CLCN7	Chloride Voltage-Gated Channel 7	Protein Coding	1
60	CLCNKA	Chloride Voltage-Gated Channel Ka	Protein Coding	1
61	CLCNKB	Chloride Voltage-Gated Channel Kb	Protein Coding	1
62	CLIC1	Chloride Intracellular Channel 1	Protein Coding	1
63	CLIC2	Chloride Intracellular Channel 2	Protein Coding	1
64	CLIC3	Chloride Intracellular Channel 3	Protein Coding	1
65	CLIC4	Chloride Intracellular Channel 4	Protein Coding	1
66	CLIC5	Chloride Intracellular Channel 5	Protein Coding	1
67	CLIC6	Chloride Intracellular Channel 6	Protein Coding	1
68	CLNS1A	Chloride Nucleotide-Sensitive Channel 1A	Protein Coding	1
69	SLC10A1	Solute Carrier Family 10 Member 1	Protein Coding	1
70	SLC4A3	Solute Carrier Family 4 Member 3	Protein Coding	1
71	SLCO1A2	Solute Carrier Organic Anion Transporter Family Member 1A2	Protein Coding	1
72	SLCO1B1	Solute Carrier Organic Anion Transporter Family Member 1B1	Protein Coding	1
73	SLCO4A1	Solute Carrier Organic Anion Transporter Family Member 4A1	Protein Coding	1
74	CACNA1B	Calcium Voltage-Gated Channel Subunit Alpha1 B	Protein Coding	1
75	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
76	CACNA1D	Calcium Voltage-Gated Channel Subunit Alpha1 D	Protein Coding	1
77	CACNA1S	Calcium Voltage-Gated Channel Subunit Alpha1 S	Protein Coding	1
78	FOXA2	Forkhead Box A2	Protein Coding	1
79	GCK	Glucokinase	Protein Coding	1
80	HNF4A	Hepatocyte Nuclear Factor 4 Alpha	Protein Coding	1
81	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
82	INS	Insulin	Protein Coding	1
83	INSR	Insulin Receptor	Protein Coding	1
84	PDX1	Pancreatic And Duodenal Homeobox 1	Protein Coding	1
85	NEUROD1	Neuronal Differentiation 1	Protein Coding	1
86	SLC2A2	Solute Carrier Family 2 Member 2	Protein Coding	1
87	HNF1A	HNF1 Homeobox A	Protein Coding	1
88	HNF1B	HNF1 Homeobox B	Protein Coding	1

Disorders associated with Hepatic ABC Transporters SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Type 2 diabetes mellitus	Enrichment	GCK, HNF1A, HNF1B, HNF4A, INSR, NEUROD1, PDX1, SLC2A2	16.00
2	Maturity-onset diabetes of the young	Enrichment	GCK, HNF1A, HNF1B, HNF4A, INS, NEUROD1, PDX1	16.00
3	Maturity-onset diabetes of the young, type 3	Enrichment	GCK, HNF1A, HNF4A	6.70
4	Permanent neonatal diabetes mellitus	Enrichment	GCK, INS, PDX1	5.56
5	Diabetes mellitus	Enrichment	GCK, HNF1A, INS	5.09
6	Maturity-onset diabetes of the young, type 1	Enrichment	GCK, HNF4A	4.86
7	Hyperinsulinism due to hnf1a deficiency	Enrichment	HNF1A, HNF4A	4.86
8	Cholestasis, progressive familial intrahepatic, 3	Enrichment	ABCB11, ABCB4	4.54
9	Cholestasis, intrahepatic, of pregnancy 3	Enrichment	ABCB11, ABCB4	4.54
10	Intrahepatic cholestasis	Enrichment	ABCB11, ABCB4	4.54
11	Chromophobe renal cell carcinoma	Enrichment	HNF1A, HNF1B	4.38
12	Bartter syndrome type 4	Enrichment	CLCNKA, CLCNKB	4.07
13	Intrahepatic cholestasis of pregnancy	Enrichment	ABCB11, ABCB4	3.77
14	Bartter syndrome, type 4b, neonatal, with sensorineural deafness	Enrichment	CLCNKA, CLCNKB	3.77
15	Type 1 diabetes mellitus	Enrichment	HNF1A, INS	3.69
16	Progressive familial intrahepatic cholestasis	Enrichment	ABCB11, ABCB4	3.23
17	Alternating hemiplegia of childhood	Enrichment	ATP1A2, ATP1A3	3.11
18	Epilepsy	Enrichment	ATP1A2, ATP1A3, KCNT1	2.89
19	Renal cell carcinoma, nonpapillary	Enrichment	HNF1A, HNF1B	2.85
20	Hepatic adenomas, familial	Enrichment	HNF1A	2.42
21	Thyrotoxic periodic paralysis 1	Enrichment	CACNA1S	2.42
22	Pancreatic agenesis 1	Enrichment	PDX1	2.42
23	Donohue syndrome	Enrichment	INSR	2.42
24	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	2.42
25	Maturity-onset diabetes of the young, type 4	Enrichment	PDX1	2.42
26	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	2.42
27	Cone dystrophy with supernormal rod responses	Enrichment	KCNV2	2.42
28	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	2.42
29	Scalp-ear-nipple syndrome	Enrichment	KCTD1	2.42
30	Maturity-onset diabetes of the young, type 6	Enrichment	NEUROD1	2.42
31	Maturity-onset diabetes of the young, type 2	Enrichment	GCK	2.42
32	Prostate cancer, hereditary, 11	Enrichment	HNF1B	2.42
33	Fanconi renotubular syndrome 4 with maturity-onset diabetes of the young	Enrichment	HNF4A	2.42
34	Congenital myopathy 18	Enrichment	CACNA1S	2.42
35	Spermatogenic failure 79	Enrichment	KCNU1	2.42
36	Primary aldosteronism, seizures, and neurologic abnormalities	Enrichment	CACNA1D	2.42
37	Hyperinsulinemic hypoglycemia, familial, 3	Enrichment	GCK	2.42
38	Brugada syndrome 3	Enrichment	CACNA1C	2.42
39	Malignant hyperthermia 5	Enrichment	CACNA1S	2.42
40	Sinoatrial node dysfunction and deafness	Enrichment	CACNA1D	2.42
41	Pulmonary hypertension, primary, 4	Enrichment	KCNK3	2.42
42	Type 1 diabetes mellitus 20	Enrichment	HNF1A	2.42
43	Developmental and epileptic encephalopathy 57	Enrichment	KCNT2	2.42
44	Progressive myoclonus epilepsy 3	Enrichment	KCTD7	2.42
45	Non-acquired combined pituitary hormone deficiency	Enrichment	FOXA2	2.42
46	Gestational diabetes	Enrichment	GCK	2.42
47	Hyperinsulinism due to hnf4a deficiency	Enrichment	HNF4A	2.42
48	Atypical timothy syndrome	Enrichment	CACNA1C	2.42
49	Aldosterone-producing adenoma with seizures and neurological abnormalities	Enrichment	CACNA1D	2.42
50	Timothy syndrome type 2	Enrichment	CACNA1C	2.42
51	Medullary sponge kidney	Enrichment	HNF1B	2.42
52	Periodic paralysis with transient compartment-like syndrome	Enrichment	CACNA1S	2.42
53	Renal dysplasia, bilateral	Enrichment	HNF1B	2.42
54	Unilateral multicystic dysplastic kidney	Enrichment	HNF1B	2.42
55	Renal dysplasia, unilateral	Enrichment	HNF1B	2.42
56	Timothy syndrome type 1	Enrichment	CACNA1C	2.42
57	Cone dystrophy with supernormal rod response	Enrichment	KCNV2	2.42
58	Cacna1c-related disorders	Enrichment	CACNA1C	2.42
59	Osteopetrosis, autosomal dominant 2	Enrichment	CLCN7	2.27
60	Cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss	Enrichment	ATP1A3	2.27
61	Colchicine resistance	Enrichment	ABCB1	2.27
62	Alternating hemiplegia of childhood 2	Enrichment	ATP1A3	2.27
63	Gallbladder disease 1	Enrichment	ABCB4	2.27
64	Fetal akinesia, respiratory insufficiency, microcephaly, polymicrogyria, and dysmorphic facies	Enrichment	ATP1A2	2.27
65	Neurodevelopmental disorder with seizures and brain abnormalities	Enrichment	CLCN3	2.27
66	Deafness, autosomal recessive 103	Enrichment	CLIC5	2.27
67	Developmental and epileptic encephalopathy 99	Enrichment	ATP1A3	2.27
68	Hypopigmentation, organomegaly, and delayed myelination and development	Enrichment	CLCN7	2.27
69	Encephalopathy, acute transient	Enrichment	ABCB1	2.27
70	Raynaud-claes syndrome	Enrichment	CLCN4	2.27
71	Hypercholanemia, familial, 2	Enrichment	SLC10A1	2.27
72	Inflammatory bowel disease 13	Enrichment	ABCB1	2.27
73	Epilepsy, idiopathic generalized 11	Enrichment	CLCN2	2.27
74	Short qt syndrome 7	Enrichment	SLC4A3	2.27
75	Developmental and epileptic encephalopathy 98	Enrichment	ATP1A2	2.27
76	Ceroid lipofuscinosis, neuronal, 15	Enrichment	CLCN6	2.27
77	Neurodevelopmental disorder with hypotonia and brain abnormalities	Enrichment	CLCN3	2.27
78	Atp1a3-related disorder	Enrichment	ATP1A3	2.27
79	Oculogyric crisis	Enrichment	ATP1A3	2.27
80	Hemiplegia	Enrichment	ATP1A3	2.27
81	X-linked intellectual disability-cardiomegaly-congestive heart failure syndrome	Enrichment	CLIC2	2.27
82	Long qt syndrome 1	Enrichment	CACNA1C, SLC2A2	2.25
83	Long qt syndrome	Enrichment	CACNA1C, CACNA1S	2.22
84	Tubulointerstitial kidney disease, autosomal dominant 1	Enrichment	HNF1B	2.12
85	Renal cysts and diabetes syndrome	Enrichment	HNF1B	2.12
86	Congenital anomalies of kidney and urinary tract 2	Enrichment	HNF1B	2.12
87	Pancreas, dorsal, agenesis of	Enrichment	PDX1	2.12
88	Fanconi-bickel syndrome	Enrichment	SLC2A2	2.12
89	Timothy syndrome	Enrichment	CACNA1C	2.12
90	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	2.12
91	Diabetes mellitus, permanent neonatal, 1	Enrichment	GCK	2.12
92	Birk-barel syndrome	Enrichment	KCNK9	2.12
93	Bone marrow failure syndrome 2	Enrichment	GCK	2.12
94	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.12
95	Epilepsy, nocturnal frontal lobe, 5	Enrichment	KCNT1	2.12
96	Developmental and epileptic encephalopathy 15	Enrichment	KCNT1	2.12
97	Long qt syndrome 8	Enrichment	CACNA1C	2.12
98	Hyperproinsulinemia	Enrichment	INS	2.12
99	Facial dysmorphism, hypertrichosis, epilepsy, intellectual/developmental delay, and gingival overgrowth syndrome	Enrichment	KCNK4	2.12
100	Hyperuricemic nephropathy, familial juvenile, 3	Enrichment	HNF1B	2.12
101	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.12
102	Congenital disorder of glycosylation, type iw, autosomal dominant	Enrichment	CACNA1D	2.12
103	Epilepsy, progressive myoclonic, 3, with or without intracellular inclusions	Enrichment	KCTD7	2.12
104	Neurodevelopmental disorder with seizures and nonepileptic hyperkinetic movements	Enrichment	CACNA1B	2.12
105	Malignant migrating partial seizures of infancy	Enrichment	KCNT1	2.12
106	Hyperinsulinism	Enrichment	HNF4A	2.12
107	Seizures, benign familial neonatal, 1	Enrichment	ATP1A3	1.97
108	Batten-turner congenital myopathy	Enrichment	CLCN1	1.97
109	Dent disease 1	Enrichment	CLCN5	1.97
110	Migraine, familial hemiplegic, 2	Enrichment	ATP1A2	1.97
111	Bartter syndrome, type 3	Enrichment	CLCNKB	1.97
112	Hyperaldosteronism, familial, type ii	Enrichment	CLCN2	1.97
113	Osteopetrosis, autosomal recessive 4	Enrichment	CLCN7	1.97
114	Nephrolithiasis, x-linked recessive, with renal failure	Enrichment	CLCN5	1.97
115	Alternating hemiplegia of childhood 1	Enrichment	ATP1A2	1.97
116	Cholestasis, benign recurrent intrahepatic, 2	Enrichment	ABCB11	1.97
117	Cholestasis, progressive familial intrahepatic, 4	Enrichment	ABCB11	1.97
118	Leukoencephalopathy with ataxia	Enrichment	CLCN2	1.97
119	Cholestasis, progressive familial intrahepatic, 2	Enrichment	ABCB11	1.97
120	Hypophosphatemic rickets, x-linked recessive	Enrichment	CLCN5	1.97
121	Charcot-marie-tooth disease, axonal, type 2dd	Enrichment	ATP1A1	1.97
122	Proteinuria, low molecular weight, with hypercalciuria and nephrocalcinosis	Enrichment	CLCN5	1.97
123	Familial hemiplegic migraine	Enrichment	ATP1A2	1.97
124	Neurogenic bladder	Enrichment	CLCN6	1.97
125	Hypomagnesemia, seizures, and impaired intellectual development 2	Enrichment	ATP1A1	1.97
126	Respiratory system disease	Enrichment	CLCN6	1.97
127	Clcn2-related leukoencephalopathy	Enrichment	CLCN2	1.97
128	Osteosclerosis	Enrichment	CLCN7	1.97
129	Type 1 diabetes mellitus 2	Enrichment	INS	1.95
130	Nijmegen breakage syndrome	Enrichment	GCK	1.95
131	Mullerian duct aplasia, unilateral renal agenesis, and cervicothoracic somite anomalies	Enrichment	HNF1B	1.95
132	Epilepsy, nocturnal frontal lobe, 1	Enrichment	KCNT1	1.95
133	Chromosome 17q12 deletion syndrome	Enrichment	HNF1B	1.95
134	Keratoderma-ichthyosis-deafness syndrome, autosomal recessive	Enrichment	HNF1A	1.95
135	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1C	1.95
136	Ciliary dyskinesia, primary, 28	Enrichment	KCNT1	1.95
137	Gingival overgrowth	Enrichment	KCNK4	1.95
138	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.95
139	Thyrotoxic periodic paralysis	Enrichment	CACNA1S	1.95
140	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	1.83
141	Neonatal diabetes mellitus	Enrichment	INS	1.83
142	Malignant hyperthermia	Enrichment	CACNA1S	1.83
143	Clear cell papillary renal cell carcinoma	Enrichment	HNF1A	1.83
144	Dystonia 12	Enrichment	ATP1A3	1.79
145	Myotonia congenita, autosomal dominant	Enrichment	CLCN1	1.79
146	Dubin-johnson syndrome	Enrichment	ABCC2	1.79
147	Myotonia congenita, autosomal recessive	Enrichment	CLCN1	1.79
148	Hyperbilirubinemia, rotor type	Enrichment	SLCO1B1	1.79
149	Osteopetrosis, autosomal dominant 1	Enrichment	CLCNKB	1.79
150	Dent disease	Enrichment	CLCN5	1.79
151	Osteopetrosis, autosomal recessive 6	Enrichment	CLCN7	1.79
152	Cerebral palsy	Enrichment	CLCN1, CLCN2	1.73
153	Insulin-like growth factor i	Enrichment	IGF1R	1.73
154	Heart conduction disease	Enrichment	CACNA1C	1.73
155	Hypophosphatemic rickets, x-linked dominant	Enrichment	CLCN5	1.67
156	Smith-lemli-opitz syndrome	Enrichment	CLCN1	1.67
157	Hyperkalemic periodic paralysis	Enrichment	CLCN1	1.67
158	Autosomal recessive osteopetrosis	Enrichment	CLCN7	1.67
159	Familial or sporadic hemiplegic migraine	Enrichment	ATP1A2	1.67
160	Hypokalemic periodic paralysis, type 1	Enrichment	CACNA1S	1.65
161	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GCK	1.65
162	Clear cell renal cell carcinoma	Enrichment	HNF1A	1.65
163	46,xy disorder of sex development	Enrichment	INSR	1.65
164	Nonsyndromic genetic hyperinsulinism	Enrichment	GCK	1.65
165	Autosomal dominant sleep-related hypermotor epilepsy	Enrichment	KCNT1	1.58
166	Gitelman syndrome	Enrichment	CLCNKB	1.57
167	Osteopetrosis	Enrichment	CLCN7	1.57
168	Congenital short qt syndrome	Enrichment	SLC4A3	1.57
169	Combined pituitary hormone deficiency	Enrichment	FOXA2	1.53
170	Cholestasis, progressive familial intrahepatic, 1	Enrichment	ABCB4	1.50
171	Metachromatic leukodystrophy	Enrichment	CLCN1	1.50
172	Pseudoxanthoma elasticum	Enrichment	ABCC2	1.50
173	Familial hypercholanemia	Enrichment	SLC10A1	1.50
174	Developmental and epileptic encephalopathy 14	Enrichment	KCNT1	1.48
175	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	1.48
176	Undetermined early-onset epileptic encephalopathy	Enrichment	ATP1A2, ATP1A3	1.44
177	Progressive myoclonus epilepsy	Enrichment	KCTD7	1.43
178	Epilepsy, familial focal, with variable foci 1	Enrichment	CLCNKB	1.43
179	Bartter disease	Enrichment	CLCNKB	1.43
180	Heritable pulmonary arterial hypertension	Enrichment	KCNK3	1.39
181	Cardiac conduction defect	Enrichment	CACNA1C	1.35
182	Digeorge syndrome	Enrichment	HNF1A	1.35
183	Congenital long qt syndrome	Enrichment	SLC2A2	1.35
184	Deafness, autosomal recessive	Enrichment	CLCNKA, CLIC5	1.34
185	Autosomal recessive nonsyndromic deafness	Enrichment	CLCNKA, CLIC5	1.33
186	Pulmonary hypertension, primary, 1	Enrichment	KCNK3	1.32
187	Nk-cell enteropathy	Enrichment	IGF1R	1.32
188	Myoclonic epilepsy of unverricht and lundborg	Enrichment	KCTD7	1.29
189	Cone-rod dystrophy 6	Enrichment	KCNV2	1.29
190	Polymicrogyria	Enrichment	ATP1A2	1.28
191	Neuronal ceroid lipofuscinosis	Enrichment	KCTD7	1.26
192	Ovarian cancer	Enrichment	HNF1A, HNF1B	1.26
193	Migraine with or without aura 1	Enrichment	CLCN1	1.24
194	Gilbert syndrome	Enrichment	SLCO1B1	1.24
195	Epilepsy, myoclonic juvenile	Enrichment	CLCN2	1.24
196	Epilepsy, idiopathic generalized	Enrichment	ABCB1	1.24
197	Movement disease	Enrichment	CLCN6	1.24
198	Cerebellar hypoplasia/atrophy, epilepsy, and global developmental delay	Enrichment	KCTD3	1.23
199	Polycystic liver disease	Enrichment	HNF4A	1.21
200	Autosomal dominant polycystic liver disease	Enrichment	HNF4A	1.21
201	Epicanthus	Enrichment	ATP1A3	1.20
202	Congenital myopathy	Enrichment	CACNA1S	1.16
203	Centronuclear myopathy	Enrichment	CACNA1S	1.12
204	Hydrocephalus, congenital, 1	Enrichment	ATP1A3	1.08
205	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	CLCNKA, CLIC5	1.08
206	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C	1.06
207	Cone dystrophy	Enrichment	KCNV2	1.06
208	Hypertension, essential	Enrichment	ATP1B1	1.06
209	Brugada syndrome	Enrichment	CACNA1C	1.03
210	Prostate cancer	Enrichment	HNF1B	0.98
211	Stargardt disease 1	Enrichment	KCNV2	0.97
212	Myocardial infarction	Enrichment	CLCN1	0.95
213	Skin disease	Enrichment	CLCN6	0.95
214	Cakut	Enrichment	HNF1B	0.92
215	Rasopathy	Enrichment	CLCN1	0.88
216	Benign epilepsy with centrotemporal spikes	Enrichment	KCNT1	0.84
217	Centralopathic epilepsy	Enrichment	KCNT1	0.82
218	Cystic fibrosis	Enrichment	CLCA4	0.80
219	Dystonia	Enrichment	ATP1A3	0.76
220	Non-syndromic x-linked intellectual disability	Enrichment	CLCN4	0.75
221	Myopathy	Enrichment	CLCN1	0.71
222	Nephrotic syndrome	Enrichment	CLCN5	0.68
223	Cone-rod dystrophy 2	Enrichment	KCNV2	0.65
224	Sensorineural hearing loss	Enrichment	CLCNKA	0.64
225	Breast cancer	Enrichment	HNF1A	0.61
226	Spastic ataxia	Enrichment	ATP1A2	0.60
227	Hereditary retinal dystrophy	Enrichment	KCNV2, NEUROD1	0.53
228	Fundus dystrophy	Enrichment	KCNV2, NEUROD1	0.53
229	Congenital nervous system abnormality	Enrichment	KCNV2	0.48
230	Nervous system disease	Enrichment	KCNV2	0.48
231	Microcephaly	Enrichment	IGF1R	0.43
232	Complex neurodevelopmental disorder	Enrichment	CACNA1C	0.43

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Hepatic ABC Transporters

Pathway Network for Hepatic ABC Transporters

Member Pathways for Hepatic ABC Transporters

Pathways in the Hepatic ABC Transporters SuperPath

Associated Genes for Hepatic ABC Transporters

Associated Disorders for Hepatic ABC Transporters

Disorders associated with Hepatic ABC Transporters SuperPath

STRING Interaction Network for Hepatic ABC Transporters

Sources for Hepatic ABC Transporters