Hippo-YAP signaling

No Pathway Network information available for Hippo-YAP signaling

Pathways in the Hippo-YAP signaling SuperPath

#	Name	Source	Genes
1	Hippo-YAP signaling	WikiPathways	LATS1 MAP4K1 MAP4K2 MAP4K3 MAP4K4 MINK1 MST1 NDRG1 NF2 RASSF1 TAFAZZIN TEAD1 TEAD2 TEAD3 TEAD4 TNIK YY1AP1 (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MAP4K4	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 4	Protein Coding	1
2	LATS1	Large Tumor Suppressor Kinase 1	Protein Coding	1
3	TEAD2	TEA Domain Transcription Factor 2	Protein Coding	1
4	TEAD1	TEA Domain Transcription Factor 1	Protein Coding	1
5	TAFAZZIN	Tafazzin, Phospholipid-Lysophospholipid Transacylase	Protein Coding	1
6	YY1AP1	YY1 Associated Protein 1	Protein Coding	1
7	NF2	NF2, Moesin-Ezrin-Radixin Like (MERLIN) Tumor Suppressor	Protein Coding	1
8	MST1	Macrophage Stimulating 1	Protein Coding	1
9	TNIK	TRAF2 And NCK Interacting Kinase	Protein Coding	1
10	RASSF1	Ras Association Domain Family Member 1	Protein Coding	1
11	NDRG1	N-Myc Downstream Regulated 1	Protein Coding	1
12	MAP4K3	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 3	Protein Coding	1
13	MAP4K1	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1	Protein Coding	1
14	TEAD3	TEA Domain Transcription Factor 3	Protein Coding	1
15	TEAD4	TEA Domain Transcription Factor 4	Protein Coding	1
16	MAP4K2	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2	Protein Coding	1
17	MINK1	Misshapen Like Kinase 1	Protein Coding	1

Disorders associated with Hippo-YAP signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Schwannomatosis, vestibular	Enrichment	NF2	2.90
2	Intellectual developmental disorder, autosomal recessive 54	Enrichment	TNIK	2.90
3	Acoustic neuroma	Enrichment	NF2	2.90
4	Sveinsson chorioretinal atrophy	Enrichment	TEAD1	2.60
5	Grange syndrome	Enrichment	YY1AP1	2.60
6	Schwannomatosis 1	Enrichment	NF2	2.60
7	Charcot-marie-tooth disease, demyelinating, type 4d	Enrichment	NDRG1	2.60
8	Retinitis pigmentosa 14	Enrichment	TEAD3	2.60
9	Charcot-marie-tooth disease type 4d	Enrichment	NDRG1	2.60
10	Malignant peritoneal mesothelioma	Enrichment	LATS1	2.60
11	Barth syndrome	Enrichment	TAFAZZIN	2.43
12	Anus, imperforate	Enrichment	MAP4K4	2.43
13	Cellular ependymoma	Enrichment	NF2	2.43
14	Tanycytic ependymoma	Enrichment	NF2	2.43
15	Papillary ependymoma	Enrichment	NF2	2.43
16	Spindle cell sarcoma	Enrichment	NF2	2.43
17	Clear cell ependymoma	Enrichment	NF2	2.43
18	Ciliary dyskinesia, primary, 22	Enrichment	RASSF1	2.30
19	Full schwannomatosis	Enrichment	NF2	2.30
20	Benign ependymoma	Enrichment	NF2	2.30
21	Myasthenic syndrome, congenital, 4a, slow-channel	Enrichment	MINK1	2.20
22	Cholangitis, primary sclerosing	Enrichment	MST1	2.20
23	Myasthenic syndrome, congenital, 4b, fast-channel	Enrichment	MINK1	2.20
24	Multiple endocrine neoplasia, type i	Enrichment	MAP4K2	2.06
25	Myasthenic syndrome, congenital, 1a, slow-channel	Enrichment	MINK1	2.06
26	Renal hypodysplasia/aplasia 1	Enrichment	MAP4K4	2.00
27	Inherited cancer-predisposing syndrome	Enrichment	MAP4K2, NF2	1.93
28	Myasthenic syndrome, congenital, 4c, associated with acetylcholine receptor deficiency	Enrichment	MINK1	1.90
29	Meningioma, familial	Enrichment	NF2	1.86
30	Meningioma	Enrichment	NF2	1.83
31	Congenital myasthenic syndrome	Enrichment	MINK1	1.76
32	Charcot-marie-tooth disease type 4	Enrichment	NDRG1	1.65
33	Arteriovenous malformations of the brain	Enrichment	MAP4K4	1.63
34	Left ventricular noncompaction	Enrichment	TAFAZZIN	1.37
35	Charcot-marie-tooth disease	Enrichment	NDRG1	1.30
36	Familial isolated dilated cardiomyopathy	Enrichment	TAFAZZIN	1.19
37	Myeloma, multiple	Enrichment	LATS1	1.17
38	Autosomal recessive non-syndromic intellectual disability	Enrichment	TNIK	1.15
39	Dilated cardiomyopathy	Enrichment	TAFAZZIN	1.02
40	Leber plus disease	Enrichment	TEAD3	0.95
41	Hereditary retinal dystrophy	Enrichment	TEAD3	0.51
42	Fundus dystrophy	Enrichment	TEAD3	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Hippo-YAP signaling

Pathway Network for Hippo-YAP signaling

Member Pathways for Hippo-YAP signaling

Pathways in the Hippo-YAP signaling SuperPath

Associated Genes for Hippo-YAP signaling

Associated Disorders for Hippo-YAP signaling

Disorders associated with Hippo-YAP signaling SuperPath

STRING Interaction Network for Hippo-YAP signaling

Sources for Hippo-YAP signaling