PathCards :: Homology Directed Repair Pathway and related pathways

Pathway network for Homology Directed Repair SuperPath

8 Pathways in the Homology Directed Repair SuperPath

	DNA Repair		Homology Directed Repair
	DNA Double-Strand Break Repair		Processing of DNA double-strand break ends
	G2/M DNA damage checkpoint		Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex
	HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA)		HDR through MMEJ (alt-NHEJ)

346 Genes in the Homology Directed Repair SuperPath

RAD50	CHEK1	MRE11	NBN	RBBP8	LOC102724334	KAT5	TOPBP1	RMI2	H4C16	H2BC26	RAD9B
RNF168	DNA2	H2BC1	BABAM1	H2AX	H2BC5	H2BC3	HUS1	ATM	PIAS4	UIMC1	ATR
H4C15	BARD1	RAD1	RAD9A	RAD17	RFC2	RFC3	RFC4	RFC5	RPA1	RPA2	RPA3
BLM	BRCA1	TOP3A	TP53BP1	UBE2N	UBE2V2	NSD2	WRN	BRCC3	RMI1	H3-4	H4C9
H2BC8	H2BC13	H2BC15	H2BC14	H2BC7	H2BC6	H2BC9	H2BC10	H2BC4	H2BC17	H2BC21	H4C1
H4C4	H4C6	H4C12	H4C11	H4C3	H4C8	H4C2	H4C5	H4C13	RHNO1	H4C14	BRIP1
ATRIP	ABRAXAS1	H2BC12	HERC2	H2BC11	RNF8	EXO1	BABAM2	MDC1	CDK2	PPP4R2	SIRT6
TIPIN	PPP4C	RAD52	RNF4	RPS27A	CLSPN	SUMO2	BRCA2	UBA52	UBB	UBC	UBE2I
CCNA2	CCNA1	TIMELESS	PARP2	RAD51AP1	POLD3	POLQ	CHEK2	PARP1	EME1	EME2	ERCC1
ERCC4	FEN1	SPIDR	ABL1	GEN1	LIG3	PCNA	POLK	RTEL1	POLE3	POLD1	POLD2
POLE	POLE2	POLH	SLX1A	POLE4	POLD4	RAD51	RAD51C	RAD51B	RAD51D	RFC1	XRCC1
XRCC2	XRCC3	SLX1B	PALB2	SEM1	MUS81	SLX4	TP53	EYA4	EYA1	EYA2	EYA3
PAXIP1	KDM4B	XRCC6	POLL	POLM	APBB1	KPNA2	LIG4	UBXN1	TDP2	RIF1	PPP5C
TDP1	PRKDC	MAPK8	DCLRE1C	SUMO1	XRCC4	XRCC5	NHEJ1	BAP1	SMARCA5	BAZ1B	KDM4A
YWHAQ	SFN	WEE1	YWHAB	YWHAE	YWHAG	YWHAH	YWHAZ	CCNB1	CDK1	CDC25C	CENPS-CORT
ISY1-RAB43	CDK7	PIAS3	MCRS1	PPIE	MAD2L2	CETN2	COPS8	ASCC3	COPS6	COPS5	POLI
PNKP	ERCC8	ALKBH2	USP43	INO80C	DDB1	DDB2	FAAP20	CENPX	EP300	ERCC2	ERCC3
ERCC5	ERCC6	FANCA	FANCC	FANCD2	FANCE	FANCB	FANCF	FANCG	ALKBH3	FAN1	SMUG1
NEIL2	RCHY1	POT1	TINF2	PRPF19	INO80E	GPS1	UBE2T	MSH6	GTF2H1	GTF2H2	GTF2H3
GTF2H4	TFPT	H2AC8	H2AC7	HMGN1	APEX1	POLN	CENPS	LIG1	GTF2H5	MGMT	MLH1
MNAT1	MPG	MSH2	MSH3	MUTYH	H2AB1	NFRKB	NTHL1	OGG1	COPS7A	ASCC1	COPS4
REV1	DTL	PMS2	POLB	POLR2A	POLR2B	POLR2C	POLR2D	POLR2E	POLR2F	POLR2G	POLR2H
POLR2I	TERF2IP	POLR2J	POLR2K	POLR2L	INO80	RNF111	ALKBH5	INO80D	ADPRS	FANCL	FANCI
NEIL3	NPLOC4	H2AJ	RAD18	XAB2	ISY1	WDR48	UVSSA	FANCM	RAD23A	RAD23B	REV3L
ACTB	COPS7B	DCLRE1B	ACD	SUMO3	BPHL	TCEA1	TDG	TERF1	TERF2	H2AC19	UBA7
UBE2B	UFD1	UNG	USP1	VCP	XPA	XPC	YY1	TRIM25	USP7	FTO	NEIL1
ACTR5	FAAP100	ELL	H2AC14	H2AC6	H2AC4	H2AC18	H2AC20	INO80B	SPRTN	ASCC2	CUL4B
CUL4A	USP45	PARG	COPS3	PIAS1	ACTL6A	RUVBL1	MBD4	CCNH	USP10	FAAP24	ZNF830
UBE2L6	COPS2	ACTR8	H2AZ2	CHD1L	ISG15	AQR	PCLAF	DCLRE1A	RBX1

*Darkness represents the genes rank within the SuperPath, via the multiplicity of each gene in the constituent pathways.

STRING interaction network for Homology Directed Repair SuperPath