hydrogen sulfide biosynthesis II (mammalian)
Pathway network for the hydrogen sulfide biosynthesis II (mammalian) SuperPath
Sources:
- PubChem
- Reactome
Pathways in the hydrogen sulfide biosynthesis II (mammalian) SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | hydrogen sulfide biosynthesis II (mammalian) | PubChem | |
| 2 | Cysteine formation from homocysteine | Reactome | |
| 3 | cysteine biosynthesis/homocysteine degradation (trans-sulfuration) | PubChem | |
| 4 | L-cysteine biosynthesis III (from L-homocysteine) | PubChem |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CBS | Cystathionine Beta-Synthase | Protein Coding | 4 |
| 2 | LOC102724560 | Cystathionine Beta-Synthase Like | Protein Coding | 4 |
| 3 | CTH | Cystathionine Gamma-Lyase | Protein Coding | 2 |
Disorders associated with hydrogen sulfide biosynthesis II (mammalian) SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Hyperhomocysteinemia | Enrichment | CBS | 3.83 |
| 2 | Cystathioninuria | Enrichment | CTH | 3.66 |
| 3 | Homocystinuria due to cystathionine beta-synthase deficiency | Enrichment | CBS | 3.35 |
| 4 | Homocystinuria | Enrichment | CBS | 3.35 |
| 5 | Connective tissue disease | Enrichment | CBS | 2.33 |
| 6 | Familial thoracic aortic aneurysm and aortic dissection | Enrichment | CBS | 2.19 |
