Hypertrophy model

No Pathway Network information available for Hypertrophy model

#	Name	Source	Genes
1	Hypertrophy model	WikiPathways	ADAM10 ANKRD1 ATF3 CCN1 DUSP14 EIF4E EIF4EBP1 HBEGF IFNG IFRD1 IL18 IL1A IL1R1 JUND MSTN MYOG NR4A3 VEGFA WDR1 ZEB1 (see all 20) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	WDR1	WD Repeat Domain 1	Protein Coding	1
2	NR4A3	Nuclear Receptor Subfamily 4 Group A Member 3	Protein Coding	1
3	VEGFA	Vascular Endothelial Growth Factor A	Protein Coding	1
4	ZEB1	Zinc Finger E-Box Binding Homeobox 1	Protein Coding	1
5	ATF3	Activating Transcription Factor 3	Protein Coding	1
6	JUND	JunD Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
7	IL18	Interleukin 18	Protein Coding	1
8	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	1
9	IL1A	Interleukin 1 Alpha	Protein Coding	1
10	CCN1	Cellular Communication Network Factor 1	Protein Coding	1
11	IFRD1	Interferon Related Developmental Regulator 1	Protein Coding	1
12	IFNG	Interferon Gamma	Protein Coding	1
13	ANKRD1	Ankyrin Repeat Domain 1	Protein Coding	1
14	MSTN	Myostatin	Protein Coding	1
15	EIF4EBP1	Eukaryotic Translation Initiation Factor 4E Binding Protein 1	Protein Coding	1
16	EIF4E	Eukaryotic Translation Initiation Factor 4E	Protein Coding	1
17	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	1
18	ADAM10	ADAM Metallopeptidase Domain 10	Protein Coding	1
19	DUSP14	Dual Specificity Phosphatase 14	Protein Coding	1
20	MYOG	Myogenin	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Periodic fever, immunodeficiency, and thrombocytopenia syndrome	Enrichment	WDR1	2.83
2	Immunodeficiency 69	Enrichment	IFNG	2.83
3	Autism 19	Enrichment	EIF4E	2.83
4	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	2.83
5	Alzheimer disease 18	Enrichment	ADAM10	2.83
6	Microvascular complications of diabetes 1	Enrichment	VEGFA	2.83
7	Reticulate acropigmentation of kitamura	Enrichment	ADAM10	2.83
8	Spinocerebellar ataxia 18	Enrichment	IFRD1	2.53
9	Muscle hypertrophy	Enrichment	MSTN	2.53
10	Myostatin-related muscle hypertrophy	Enrichment	MSTN	2.53
11	Tuberous sclerosis 1	Enrichment	IFNG	2.35
12	Corneal dystrophy, posterior polymorphous, 3	Enrichment	ZEB1	2.35
13	Corneal dystrophy, fuchs endothelial, 6	Enrichment	ZEB1	2.35
14	Hepatitis c virus	Enrichment	IFNG	2.35
15	Tuberous sclerosis 2	Enrichment	IFNG	2.35
16	Intellectual developmental disorder, autosomal dominant 61	Enrichment	WDR1	2.35
17	Intraocular pressure quantitative trait locus	Enrichment	ZEB1	2.35
18	Dowling-degos disease 1	Enrichment	ADAM10	2.23
19	Corneal dystrophy	Enrichment	ZEB1	2.23
20	Chondrosarcoma, extraskeletal myxoid	Enrichment	NR4A3	2.13
21	Fuchs' endothelial dystrophy	Enrichment	ZEB1	2.13
22	Idiopathic aplastic anemia	Enrichment	IFNG	2.13
23	Corneal dystrophy, posterior polymorphous, 1	Enrichment	ZEB1	2.05
24	Aplastic anemia	Enrichment	IFNG	1.83
25	Human immunodeficiency virus type 1	Enrichment	IFNG	1.58
26	Familial isolated dilated cardiomyopathy	Enrichment	ANKRD1	1.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Hypertrophy model