IL-26 signaling pathways

No Pathway Network information available for IL-26 signaling pathways

Pathways in the IL-26 signaling pathways SuperPath

#	Name	Source	Genes
1	IL-26 signaling pathways	WikiPathways	ACTA2 ATP6V0D2 BAX CASP3 CCL20 CSF2 CTSK CXCL8 DCSTAMP DDIT3 DEFB4A EPHA3 ICAM1 IL10 IL10RB IL17A IL1B IL20RA IL26 IL33 IL6 MMP1 MMP9 MPO MT-CO2 NFATC1 RELA RORC SMAD2 SOCS3 STAT1 STAT3 TGFB1 TNF TNFSF11 (see all 35) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	EPHA3	EPH Receptor A3	Protein Coding	1
2	IL26	Interleukin 26	Protein Coding	1
3	IL20RA	Interleukin 20 Receptor Subunit Alpha	Protein Coding	1
4	MT-CO2	Mitochondrially Encoded Cytochrome C Oxidase II	Protein Coding	1
5	MMP1	Matrix Metallopeptidase 1	Protein Coding	1
6	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
7	SMAD2	SMAD Family Member 2	Protein Coding	1
8	IL10RB	Interleukin 10 Receptor Subunit Beta	Protein Coding	1
9	DDIT3	DNA Damage Inducible Transcript 3	Protein Coding	1
10	MPO	Myeloperoxidase	Protein Coding	1
11	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
12	IL33	Interleukin 33	Protein Coding	1
13	SOCS3	Suppressor Of Cytokine Signaling 3	Protein Coding	1
14	TNFSF11	TNF Superfamily Member 11	Protein Coding	1
15	CASP3	Caspase 3	Protein Coding	1
16	DCSTAMP	Dendrocyte Expressed Seven Transmembrane Protein	Protein Coding	1
17	TNF	Tumor Necrosis Factor	Protein Coding	1
18	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
19	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
20	CCL20	C-C Motif Chemokine Ligand 20	Protein Coding	1
21	RORC	RAR Related Orphan Receptor C	Protein Coding	1
22	ACTA2	Actin Alpha 2, Smooth Muscle	Protein Coding	1
23	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	1
24	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
25	IL17A	Interleukin 17A	Protein Coding	1
26	IL10	Interleukin 10	Protein Coding	1
27	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
28	IL6	Interleukin 6	Protein Coding	1
29	IL1B	Interleukin 1 Beta	Protein Coding	1
30	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
31	ATP6V0D2	ATPase H+ Transporting V0 Subunit D2	Protein Coding	1
32	DEFB4A	Defensin Beta 4A	Protein Coding	1
33	CTSK	Cathepsin K	Protein Coding	1
34	CSF2	Colony Stimulating Factor 2	Protein Coding	1
35	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	1

Disorders associated with IL-26 signaling pathways SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, IL10RB, TGFB1	6.50
2	Cerebral malaria	Enrichment	ICAM1, TNF	4.41
3	Inflammatory bowel disease 25, autosomal recessive	Enrichment	IL10RB, TGFB1	4.02
4	Alzheimer's disease	Enrichment	MPO, TNF	3.30
5	Malaria	Enrichment	ICAM1, TNF	2.80
6	Pycnodysostosis	Enrichment	CTSK	2.59
7	Dermatitis, atopic, 4	Enrichment	SOCS3	2.59
8	Graft-versus-host disease	Enrichment	IL10	2.59
9	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.59
10	Immunodeficiency 42	Enrichment	RORC	2.59
11	Immunodeficiency 31a	Enrichment	STAT1	2.59
12	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.59
13	Immunodeficiency 31b	Enrichment	STAT1	2.59
14	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.59
15	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.59
16	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.59
17	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.59
18	Systemic lupus erythematosus	Enrichment	IL10, TNF	2.35
19	Camurati-engelmann disease 1	Enrichment	TGFB1	2.29
20	Aortic aneurysm, familial thoracic 2	Enrichment	ACTA2	2.29
21	Smooth muscle dysfunction syndrome	Enrichment	ACTA2	2.29
22	Aortic aneurysm, familial thoracic 6	Enrichment	ACTA2	2.29
23	Moyamoya disease 5	Enrichment	ACTA2	2.29
24	Osteopetrosis, autosomal recessive 2	Enrichment	TNFSF11	2.29
25	Immunodeficiency 31c	Enrichment	STAT1	2.29
26	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.29
27	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.29
28	Immunodeficiency 127	Enrichment	TNF	2.29
29	Rela fusion-positive ependymoma	Enrichment	RELA	2.29
30	Recessive dystrophic epidermolysis bullosa	Enrichment	MMP1	2.29
31	Camurati-engelmann disease	Enrichment	TGFB1	2.29
32	Metaphyseal anadysplasia 2	Enrichment	MMP9	2.29
33	Metaphyseal anadysplasia	Enrichment	MMP9	2.29
34	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	ACTA2, SMAD2	2.24
35	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	2.11
36	Psoriatic arthritis	Enrichment	TNF	2.11
37	Nail disorder, nonsyndromic congenital, 9	Enrichment	CTSK	2.11
38	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	2.11
39	Hyper ige syndrome	Enrichment	STAT3	2.11
40	Loeys-dietz syndrome 1	Enrichment	SMAD2	2.11
41	Inflammatory bowel disease 25	Enrichment	IL10RB	2.11
42	Myxoid liposarcoma	Enrichment	DDIT3	2.11
43	T-cell acute lymphoblastic leukemia	Enrichment	BAX	2.11
44	Migraine without aura	Enrichment	TNF	2.11
45	Kaposi sarcoma	Enrichment	IL6	1.99
46	Myeloperoxidase deficiency	Enrichment	MPO	1.99
47	Autoimmune lymphoproliferative syndrome	Enrichment	ACTA2	1.99
48	Hepatitis b	Enrichment	IL10RB	1.99
49	Autosomal recessive osteopetrosis	Enrichment	TNFSF11	1.99
50	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.99
51	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.89
52	Vascular dementia	Enrichment	TNF	1.89
53	Moyamoya disease 1	Enrichment	ACTA2	1.81
54	Type 1 diabetes mellitus	Enrichment	IL6	1.81
55	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.81
56	Alzheimer's disease 1	Enrichment	MPO	1.75
57	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.69
58	Rheumatoid arthritis	Enrichment	IL10	1.64
59	Inflammatory bowel disease 1	Enrichment	IL6	1.64
60	Mitochondrial myopathy, infantile, transient	Enrichment	MT-CO2	1.64
61	Loeys-dietz syndrome	Enrichment	SMAD2	1.64
62	Familial colorectal cancer	Enrichment	MT-CO2	1.59
63	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	MT-CO2	1.59
64	Primary bone dysplasia	Enrichment	CTSK	1.59
65	Asthma	Enrichment	TNF	1.55
66	Osteochondrodysplasia	Enrichment	CTSK	1.55
67	Acute promyelocytic leukemia	Enrichment	STAT3	1.48
68	Lung cancer susceptibility 3	Enrichment	ACTA2	1.45
69	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	MT-CO2	1.45
70	Alzheimer disease, familial, 1	Enrichment	MPO	1.37
71	Human immunodeficiency virus type 1	Enrichment	IL10	1.34
72	Arteriovenous malformations of the brain	Enrichment	IL6	1.32
73	Behcet syndrome	Enrichment	IL10	1.32
74	Diffuse large b-cell lymphoma	Enrichment	STAT3	1.32
75	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	MT-CO2	1.26
76	Scoliosis	Enrichment	CTSK	1.22
77	Tetralogy of fallot	Enrichment	MT-CO2	1.19
78	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-CO2	1.19
79	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-CO2	1.19
80	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-CO2	1.19
81	Camptodactyly of fingers	Enrichment	MT-CO2	1.19
82	Severe covid-19	Enrichment	IL10RB	1.14
83	Lung cancer	Enrichment	ACTA2	1.10
84	Cystic fibrosis	Enrichment	TGFB1	1.10
85	Connective tissue disease	Enrichment	ACTA2	1.10
86	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-CO2	1.04
87	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-CO2	1.03
88	Type 2 diabetes mellitus	Enrichment	IL6	0.99
89	Gastric cancer	Enrichment	IL1B	0.98
90	Hypertelorism	Enrichment	MT-CO2	0.90
91	Leigh syndrome, nuclear	Enrichment	MT-CO2	0.79
92	Leigh disease	Enrichment	MT-CO2	0.75
93	Colorectal cancer	Enrichment	BAX	0.69
94	Mitochondrial disease	Enrichment	MT-CO2	0.69
95	Leber plus disease	Enrichment	MT-CO2	0.66
96	Retinitis pigmentosa	Enrichment	MT-CO2	0.37

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

IL-26 signaling pathways

Pathway Network for IL-26 signaling pathways

Member Pathways for IL-26 signaling pathways

Pathways in the IL-26 signaling pathways SuperPath

Associated Genes for IL-26 signaling pathways

Associated Disorders for IL-26 signaling pathways

Disorders associated with IL-26 signaling pathways SuperPath

STRING Interaction Network for IL-26 signaling pathways

Sources for IL-26 signaling pathways