IL1 and megakaryocytes in obesity

No Pathway Network information available for IL1 and megakaryocytes in obesity

Pathways in the IL1 and megakaryocytes in obesity SuperPath

#	Name	Source	Genes
1	IL1 and megakaryocytes in obesity	WikiPathways	CCL2 CCR3 F2 F2R FCER1A HBEGF ICAM1 IFNG IL18 IL1B IL1R1 IRAK1 MMP9 MYD88 NFKB1 NLRP3 PIK3CA PLA2G7 S100A9 SELENBP1 TIMP1 TIMP2 TLR1 TLR2 (see all 24) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SELENBP1	Selenium Binding Protein 1	Protein Coding	1
2	PLA2G7	Phospholipase A2 Group VII	Protein Coding	1
3	TLR2	Toll Like Receptor 2	Protein Coding	1
4	TLR1	Toll Like Receptor 1	Protein Coding	1
5	TIMP2	TIMP Metallopeptidase Inhibitor 2	Protein Coding	1
6	TIMP1	TIMP Metallopeptidase Inhibitor 1	Protein Coding	1
7	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
8	S100A9	S100 Calcium Binding Protein A9	Protein Coding	1
9	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
10	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
11	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	1
12	MMP9	Matrix Metallopeptidase 9	Protein Coding	1
13	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	1
14	IL18	Interleukin 18	Protein Coding	1
15	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	1
16	IL1B	Interleukin 1 Beta	Protein Coding	1
17	IFNG	Interferon Gamma	Protein Coding	1
18	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
19	FCER1A	Fc Epsilon Receptor Ia	Protein Coding	1
20	F2R	Coagulation Factor II Thrombin Receptor	Protein Coding	1
21	F2	Coagulation Factor II, Thrombin	Protein Coding	1
22	HBEGF	Heparin Binding EGF Like Growth Factor	Protein Coding	1
23	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	1
24	NLRP3	NLR Family Pyrin Domain Containing 3	Protein Coding	1

Disorders associated with IL1 and megakaryocytes in obesity SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Human immunodeficiency virus type 1	Enrichment	CCL2, IFNG	3.35
2	Macrodactyly	Enrichment	PIK3CA	2.75
3	Leprosy 3	Enrichment	TLR2	2.75
4	Cinca syndrome	Enrichment	NLRP3	2.75
5	Immunodeficiency 68	Enrichment	MYD88	2.75
6	Keratoendotheliitis fugax hereditaria	Enrichment	NLRP3	2.75
7	Macroglobulinemia, waldenstrom 1	Enrichment	MYD88	2.75
8	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.75
9	Prothrombin deficiency, congenital	Enrichment	F2	2.75
10	Familial cold autoinflammatory syndrome 1	Enrichment	NLRP3	2.75
11	Cowden syndrome 5	Enrichment	PIK3CA	2.75
12	Leprosy 5	Enrichment	TLR1	2.75
13	Muckle-wells syndrome	Enrichment	NLRP3	2.75
14	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.75
15	Immunodeficiency 69	Enrichment	IFNG	2.75
16	Deafness, autosomal dominant 34, with or without inflammation	Enrichment	NLRP3	2.75
17	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	2.75
18	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.75
19	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.75
20	Pregnancy loss, recurrent 2	Enrichment	F2	2.75
21	Platelet-activating factor acetylhydrolase deficiency	Enrichment	PLA2G7	2.75
22	Extraoral halitosis due to methanethiol oxidase deficiency	Enrichment	SELENBP1	2.75
23	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.75
24	Hypospadias	Enrichment	PIK3CA	2.75
25	Prothrombin deficiency	Enrichment	F2	2.75
26	Rare venous malformation	Enrichment	PIK3CA	2.75
27	Diaphragmatic eventration	Enrichment	PIK3CA	2.75
28	Waldenstram macroglobulinemia	Enrichment	MYD88	2.75
29	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.75
30	Cryopyrin associated periodic syndrome	Enrichment	NLRP3	2.75
31	Rare combined vascular malformation	Enrichment	PIK3CA	2.75
32	Cavernous lymphangioma	Enrichment	PIK3CA	2.75
33	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.75
34	Familial amyloid nephropathy with urticaria and deafness	Enrichment	NLRP3	2.75
35	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.75
36	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.75
37	Macrodactyly of toe	Enrichment	PIK3CA	2.75
38	Gastric cancer	Enrichment	IL1B, PIK3CA	2.59
39	Keratosis, seborrheic	Enrichment	PIK3CA	2.45
40	Noonan syndrome 8	Enrichment	PIK3CA	2.45
41	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.45
42	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.45
43	Metaphyseal anadysplasia 2	Enrichment	MMP9	2.45
44	Pericardial effusion	Enrichment	NLRP3	2.45
45	Metaphyseal anadysplasia	Enrichment	MMP9	2.45
46	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	MYD88	2.45
47	Common variable immunodeficiency 12	Enrichment	NFKB1	2.45
48	Pompe disease, infantile-onset	Enrichment	PIK3CA	2.28
49	Tuberous sclerosis 1	Enrichment	IFNG	2.28
50	Hepatitis c virus	Enrichment	IFNG	2.28
51	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA	2.28
52	Tuberous sclerosis 2	Enrichment	IFNG	2.28
53	Keratoacanthoma	Enrichment	PIK3CA	2.28
54	Cerebral sinovenous thrombosis	Enrichment	F2	2.28
55	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA	2.15
56	Cerebrovascular disease	Enrichment	PIK3CA	2.15
57	Familial cerebral cavernous malformations	Enrichment	PIK3CA	2.15
58	Cerebral malaria	Enrichment	ICAM1	2.15
59	Pediatric systemic lupus erythematosus	Enrichment	IRAK1	2.15
60	Capillary malformations, congenital	Enrichment	PIK3CA	2.05
61	Hemimegalencephaly	Enrichment	PIK3CA	2.05
62	Idiopathic aplastic anemia	Enrichment	IFNG	2.05
63	Colorectal cancer	Enrichment	PIK3CA, TLR2	1.99
64	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.98
65	Cowden syndrome 1	Enrichment	PIK3CA	1.98
66	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.98
67	Breast adenocarcinoma	Enrichment	PIK3CA	1.98
68	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.98
69	Nevus, epidermal	Enrichment	PIK3CA	1.91
70	Thrombophilia due to thrombin defect	Enrichment	F2	1.91
71	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	1.91
72	Gallbladder cancer	Enrichment	PIK3CA	1.91
73	Common variable immunodeficiency	Enrichment	NFKB1	1.91
74	Rheumatoid arthritis	Enrichment	TLR1	1.80
75	Arteriovenous malformation	Enrichment	PIK3CA	1.80
76	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.80
77	Cowden syndrome	Enrichment	PIK3CA	1.80
78	Stroke, ischemic	Enrichment	F2	1.76
79	Myopathy, x-linked, with excessive autophagy	Enrichment	PIK3CA	1.76
80	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.76
81	Aplastic anemia	Enrichment	IFNG	1.76
82	Lung non-small cell carcinoma	Enrichment	PIK3CA	1.71
83	Meningioma	Enrichment	PIK3CA	1.68
84	Lip and oral cavity carcinoma	Enrichment	PIK3CA	1.68
85	Lynch syndrome	Enrichment	PIK3CA	1.58
86	Arteriovenous malformations of the brain	Enrichment	NLRP3	1.48
87	Diffuse large b-cell lymphoma	Enrichment	MYD88	1.48
88	Endometrial cancer	Enrichment	PIK3CA	1.44
89	Hepatocellular carcinoma	Enrichment	PIK3CA	1.42
90	Malaria	Enrichment	ICAM1	1.40
91	Autoinflammatory disease	Enrichment	NLRP3	1.38
92	Bladder cancer	Enrichment	PIK3CA	1.30
93	Prostate cancer	Enrichment	PIK3CA	1.30
94	Lung cancer	Enrichment	PIK3CA	1.26
95	Systemic lupus erythematosus	Enrichment	IRAK1	1.18
96	Cerebral palsy	Enrichment	F2	1.18
97	Hereditary breast carcinoma	Enrichment	PIK3CA	1.12
98	Hypertelorism	Enrichment	PIK3CA	1.05
99	Breast cancer	Enrichment	PIK3CA	0.90
100	Ovarian cancer	Enrichment	PIK3CA	0.78

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

IL1 and megakaryocytes in obesity

Pathway Network for IL1 and megakaryocytes in obesity

Member Pathways for IL1 and megakaryocytes in obesity

Pathways in the IL1 and megakaryocytes in obesity SuperPath

Associated Genes for IL1 and megakaryocytes in obesity

Associated Disorders for IL1 and megakaryocytes in obesity

Disorders associated with IL1 and megakaryocytes in obesity SuperPath

STRING Interaction Network for IL1 and megakaryocytes in obesity

Sources for IL1 and megakaryocytes in obesity