Immune response CCR3 signaling in eosinophils

No Pathway Network information available for Immune response CCR3 signaling in eosinophils

Pathways in the Immune response CCR3 signaling in eosinophils SuperPath

#	Name	Source	Genes
1	Immune response CCR3 signaling in eosinophils	GeneGo (Thomson Reuters)	ACTB ACTG1 ACTR2 ACTR3 ACTR3B ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CALM1 CALM2 CALM3 CCL11 CCL13 CCL24 CCL26 CCL5 CCL7 CCL8 CCR3 CFL1 CFL2 CYBA CYBB DIAPH1 FGR GNAI1 GNAI2 GNAI3 GNAO1 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 HCK HRAS ITPR1 ITPR2 ITPR3 LIMK2 MAP2K1 MAP2K2 MAP2K4 MAP3K1 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH16 MYH2 MYH3 MYH4 MYH6 MYH7 MYH8 MYH9 MYL1 MYL11 MYL12A MYL12B MYL2 MYL3 MYL4 MYL5 MYL6 MYL6B MYL7 MYL9 MYLK MYLK2 MYLK3 NCF1 NCF2 NOS2 PAK1 PDPK1 PFN1 PFN2 PIK3CG PIK3R5 PLA2G4A PLA2G4C PLCB2 PPP1CB PPP1R12A PRKCA PRKCZ RAC1 RAC2 RAF1 RHOA ROCK1 ROCK2 SRC TIAM1 VAV2 WAS (see all 120) (see less)
2	Inhibitory action of Lipoxins on neutrophil migration	GeneGo (Thomson Reuters)	ACTB ACTG1 ACTN1 ACTN2 ACTN3 ACTN4 ACTR2 ACTR3 ACTR3B AKT1 AKT2 AKT3 ARPC1A ARPC1B ARPC2 ARPC3 ARPC4 ARPC5 CFL1 CFL2 CFTR CXCL8 CXCR1 CXCR2 FPR2 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 ICAM1 ITGAL ITGB2 LIMK1 LTB4R MAPK1 MAPK3 MYH1 MYH10 MYH11 MYH13 MYH14 MYH15 MYH16 MYH2 MYH3 MYH4 MYH6 MYH7 MYH8 MYH9 MYL1 MYL11 MYL12A MYL12B MYL2 MYL3 MYL4 MYL5 MYL6 MYL6B MYL7 MYL9 MYLK MYLK2 MYLK3 PAK1 PDPK1 PIK3CG PIK3R5 PIP5K1A PIP5K1B PIP5K1C PLD1 PLPP6 PPP1CB PPP1R12A PREX1 PRKCZ RAC1 RAC2 TLN1 TLN2 (see all 100) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACTB	Actin Beta	Protein Coding	2
2	ACTG1	Actin Gamma 1	Protein Coding	2
3	CFL1	Cofilin 1	Protein Coding	2
4	CFL2	Cofilin 2	Protein Coding	2
5	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
6	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
7	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
8	GNAO1	G Protein Subunit Alpha O1	Protein Coding	2
9	GNAZ	G Protein Subunit Alpha Z	Protein Coding	2
10	GNB1	G Protein Subunit Beta 1	Protein Coding	2
11	GNB2	G Protein Subunit Beta 2	Protein Coding	2
12	GNB3	G Protein Subunit Beta 3	Protein Coding	2
13	GNG3	G Protein Subunit Gamma 3	Protein Coding	2
14	GNG4	G Protein Subunit Gamma 4	Protein Coding	2
15	GNG5	G Protein Subunit Gamma 5	Protein Coding	2
16	GNG7	G Protein Subunit Gamma 7	Protein Coding	2
17	GNG10	G Protein Subunit Gamma 10	Protein Coding	2
18	GNG11	G Protein Subunit Gamma 11	Protein Coding	2
19	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	2
20	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	2
21	MYH1	Myosin Heavy Chain 1	Protein Coding	2
22	MYH2	Myosin Heavy Chain 2	Protein Coding	2
23	MYH3	Myosin Heavy Chain 3	Protein Coding	2
24	MYH4	Myosin Heavy Chain 4	Protein Coding	2
25	MYH6	Myosin Heavy Chain 6	Protein Coding	2
26	MYH7	Myosin Heavy Chain 7	Protein Coding	2
27	MYH8	Myosin Heavy Chain 8	Protein Coding	2
28	MYH9	Myosin Heavy Chain 9	Protein Coding	2
29	MYH10	Myosin Heavy Chain 10	Protein Coding	2
30	MYH11	Myosin Heavy Chain 11	Protein Coding	2
31	MYL1	Myosin Light Chain 1	Protein Coding	2
32	MYL2	Myosin Light Chain 2	Protein Coding	2
33	MYL3	Myosin Light Chain 3	Protein Coding	2
34	MYL4	Myosin Light Chain 4	Protein Coding	2
35	MYL5	Myosin Light Chain 5	Protein Coding	2
36	MYL6	Myosin Light Chain 6	Protein Coding	2
37	MYLK	Myosin Light Chain Kinase	Protein Coding	2
38	PPP1R12A	Protein Phosphatase 1 Regulatory Subunit 12A	Protein Coding	2
39	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	2
40	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
41	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	2
42	PPP1CB	Protein Phosphatase 1 Catalytic Subunit Beta	Protein Coding	2
43	PRKCZ	Protein Kinase C Zeta	Protein Coding	2
44	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
45	RAC1	Rac Family Small GTPase 1	Protein Coding	2
46	RAC2	Rac Family Small GTPase 2	Protein Coding	2
47	MYH13	Myosin Heavy Chain 13	Protein Coding	2
48	ARPC5	Actin Related Protein 2/3 Complex Subunit 5	Protein Coding	2
49	ARPC4	Actin Related Protein 2/3 Complex Subunit 4	Protein Coding	2
50	ARPC3	Actin Related Protein 2/3 Complex Subunit 3	Protein Coding	2
51	ARPC1B	Actin Related Protein 2/3 Complex Subunit 1B	Protein Coding	2
52	ACTR3	Actin Related Protein 3	Protein Coding	2
53	ACTR2	Actin Related Protein 2	Protein Coding	2
54	ARPC2	Actin Related Protein 2/3 Complex Subunit 2	Protein Coding	2
55	MYL9	Myosin Light Chain 9	Protein Coding	2
56	ARPC1A	Actin Related Protein 2/3 Complex Subunit 1A	Protein Coding	2
57	MYL12A	Myosin Light Chain 12A	Protein Coding	2
58	GNB5	G Protein Subunit Beta 5	Protein Coding	2
59	MYH15	Myosin Heavy Chain 15	Protein Coding	2
60	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
61	MYL11	Myosin Light Chain 11	Protein Coding	2
62	GNG13	G Protein Subunit Gamma 13	Protein Coding	2
63	GNG2	G Protein Subunit Gamma 2	Protein Coding	2
64	GNG12	G Protein Subunit Gamma 12	Protein Coding	2
65	ACTR3B	Actin Related Protein 3B	Protein Coding	2
66	MYL7	Myosin Light Chain 7	Protein Coding	2
67	GNB4	G Protein Subunit Beta 4	Protein Coding	2
68	MYH14	Myosin Heavy Chain 14	Protein Coding	2
69	MYH16	Myosin Heavy Chain 16	Protein Coding	2
70	MYLK2	Myosin Light Chain Kinase 2	Protein Coding	2
71	MYLK3	Myosin Light Chain Kinase 3	Protein Coding	2
72	GNG8	G Protein Subunit Gamma 8	Protein Coding	2
73	MYL12B	Myosin Light Chain 12B	Protein Coding	2
74	MYL6B	Myosin Light Chain 6B	Protein Coding	2
75	RHOA	Ras Homolog Family Member A	Protein Coding	1
76	CALM1	Calmodulin 1	Protein Coding	1
77	CALM2	Calmodulin 2	Protein Coding	1
78	CALM3	Calmodulin 3	Protein Coding	1
79	CCR3	C-C Motif Chemokine Receptor 3	Protein Coding	1
80	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
81	CYBA	Cytochrome B-245 Alpha Chain	Protein Coding	1
82	CYBB	Cytochrome B-245 Beta Chain	Protein Coding	1
83	DIAPH1	Diaphanous Related Formin 1	Protein Coding	1
84	FGR	FGR Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
85	HCK	HCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
86	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
87	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
88	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
89	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
90	LIMK2	LIM Domain Kinase 2	Protein Coding	1
91	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
92	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	1
93	NOS2	Nitric Oxide Synthase 2	Protein Coding	1
94	PFN1	Profilin 1	Protein Coding	1
95	PFN2	Profilin 2	Protein Coding	1
96	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
97	PLCB2	Phospholipase C Beta 2	Protein Coding	1
98	PRKCA	Protein Kinase C Alpha	Protein Coding	1
99	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
100	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
101	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
102	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	1
103	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	1
104	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
105	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
106	CCL5	C-C Motif Chemokine Ligand 5	Protein Coding	1
107	CCL7	C-C Motif Chemokine Ligand 7	Protein Coding	1
108	CCL8	C-C Motif Chemokine Ligand 8	Protein Coding	1
109	CCL11	C-C Motif Chemokine Ligand 11	Protein Coding	1
110	CCL13	C-C Motif Chemokine Ligand 13	Protein Coding	1
111	CCL24	C-C Motif Chemokine Ligand 24	Protein Coding	1
112	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	1
113	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
114	TIAM1	TIAM Rac1 Associated GEF 1	Protein Coding	1
115	VAV2	Vav Guanine Nucleotide Exchange Factor 2	Protein Coding	1
116	WAS	WASP Actin Nucleation Promoting Factor	Protein Coding	1
117	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
118	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	1
119	CCL26	C-C Motif Chemokine Ligand 26	Protein Coding	1
120	NCF1	Neutrophil Cytosolic Factor 1	Protein Coding	1
121	ACTN4	Actinin Alpha 4	Protein Coding	1
122	ACTN1	Actinin Alpha 1	Protein Coding	1
123	ACTN2	Actinin Alpha 2	Protein Coding	1
124	ACTN3	Actinin Alpha 3	Protein Coding	1
125	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
126	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
127	CFTR	CF Transmembrane Conductance Regulator	Protein Coding	1
128	LTB4R	Leukotriene B4 Receptor	Protein Coding	1
129	FPR2	Formyl Peptide Receptor 2	Protein Coding	1
130	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
131	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
132	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	1
133	CXCR2	C-X-C Motif Chemokine Receptor 2	Protein Coding	1
134	ITGAL	Integrin Subunit Alpha L	Protein Coding	1
135	ITGB2	Integrin Subunit Beta 2	Protein Coding	1
136	LIMK1	LIM Domain Kinase 1	Protein Coding	1
137	PLD1	Phospholipase D1	Protein Coding	1
138	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
139	TLN1	Talin 1	Protein Coding	1
140	PIP5K1A	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha	Protein Coding	1
141	PIP5K1B	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta	Protein Coding	1
142	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
143	PIP5K1C	Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma	Protein Coding	1
144	PREX1	Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1	Protein Coding	1
145	TLN2	Talin 2	Protein Coding	1
146	PLPP6	Phospholipid Phosphatase 6	Protein Coding	1

Disorders associated with Immune response CCR3 signaling in eosinophils SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Chronic granulomatous disease	Enrichment	CYBA, CYBB, NCF1, NCF2	6.15
2	Noonan syndrome 1	Enrichment	HRAS, MAP2K1, MAP2K2, PPP1CB, RAF1	5.83
3	Rasopathy	Enrichment	HRAS, MAP2K1, MAP2K2, PPP1CB, RAF1	5.55
4	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, MAP2K1, MAP2K2, RAF1	5.13
5	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	4.44
6	Baraitser-winter cerebrofrontofacial syndrome	Enrichment	ACTB, ACTG1	4.27
7	Cardiomyopathy, familial hypertrophic, 1	Enrichment	MYH6, MYH7, MYLK2, RAF1	4.27
8	Familial hypertrophic cardiomyopathy	Enrichment	ACTN2, MYH7, MYL2, MYL3	4.02
9	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	3.87
10	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF1, NCF2	3.64
11	Hypertrophic cardiomyopathy	Enrichment	ACTN2, MYH7, MYL2, MYL3	3.56
12	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	MYH11, MYLK	3.50
13	Familial sick sinus syndrome	Enrichment	GNB2, MYH6	3.50
14	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	3.34
15	Granulomatous disease, chronic, x-linked	Enrichment	CYBB, NCF1	3.34
16	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	3.34
17	Visceral myopathy 1	Enrichment	MYH11, MYLK	3.28
18	Microcephaly	Enrichment	ACTB, ACTG1, DIAPH1, GNAO1, GNB1, MAPK1	3.11
19	Noonan syndrome 3	Enrichment	HRAS, RAF1	2.80
20	Familial thoracic aortic aneurysm and dissection	Enrichment	MYH11, MYLK	2.73
21	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, RAF1	2.68
22	Long qt syndrome	Enrichment	CALM1, CALM2, MYH6	2.60
23	Cardiomyopathy, familial hypertrophic, 4	Enrichment	MYH7, NCF1	2.57
24	Arteriovenous malformation	Enrichment	HRAS, MAP2K1	2.57
25	Dilated cardiomyopathy	Enrichment	ACTN2, MYH6, MYH7, MYL2	2.54
26	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS, MAP2K1	2.48
27	Lung non-small cell carcinoma	Enrichment	HRAS, MAP2K1	2.39
28	Aortic aneurysm, familial thoracic 1	Enrichment	MYH11, MYLK	2.34
29	Congenital myopathy 4a, autosomal dominant	Enrichment	MYH7, MYL2	2.28
30	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ACTG1, MYH14, MYH9	2.18
31	Cardiomyopathy, dilated, 1e	Enrichment	MYH7, MYL2	2.17
32	Familial isolated dilated cardiomyopathy	Enrichment	ACTN2, MYH6, MYH7	2.16
33	Proteus syndrome	Enrichment	AKT1	2.13
34	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.13
35	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1a	Enrichment	MYH3	2.13
36	Baraitser-winter syndrome 1	Enrichment	ACTB	2.13
37	Focal segmental glomerulosclerosis 1	Enrichment	ACTN4	2.13
38	Deafness, autosomal dominant 17	Enrichment	MYH9	2.13
39	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.13
40	Cardiomyopathy, familial hypertrophic, 8	Enrichment	MYL3	2.13
41	Cardiomyopathy, dilated, 1aa, with or without left ventricular noncompaction	Enrichment	ACTN2	2.13
42	Cardiac valvular dysplasia 1	Enrichment	PLD1	2.13
43	Cardiomyopathy, dilated, 1ee	Enrichment	MYH6	2.13
44	Sick sinus syndrome 3	Enrichment	MYH6	2.13
45	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	2.13
46	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.13
47	Ventricular tachycardia, familial	Enrichment	GNAI2	2.13
48	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.13
49	Noonan syndrome 13	Enrichment	MAPK1	2.13
50	Deafness, autosomal dominant 4a	Enrichment	MYH14	2.13
51	Congenital myopathy 8	Enrichment	ACTN2	2.13
52	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.13
53	Congenital smooth muscle hamartoma, with or without hemihypertrophy	Enrichment	ACTB	2.13
54	Immunodeficiency 71 with inflammatory disease and congenital thrombocytopenia	Enrichment	ARPC1B	2.13
55	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.13
56	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	2.13
57	Atrial fibrillation, familial, 18	Enrichment	MYL4	2.13
58	Nemaline myopathy 7	Enrichment	CFL2	2.13
59	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	2.13
60	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.13
61	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.13
62	Actn3 deficiency	Enrichment	ACTN3	2.13
63	Becker nevus syndrome	Enrichment	ACTB	2.13
64	Dystonia-deafness syndrome 1	Enrichment	ACTB	2.13
65	Cardiomyopathy, familial hypertrophic, 14	Enrichment	MYH6	2.13
66	Cowden syndrome 6	Enrichment	AKT1	2.13
67	Bleeding disorder, platelet-type, 15	Enrichment	ACTN1	2.13
68	Peripheral neuropathy, myopathy, hoarseness, and hearing loss	Enrichment	MYH14	2.13
69	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.13
70	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.13
71	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.13
72	Noonan syndrome-like disorder with loose anagen hair 2	Enrichment	PPP1CB	2.13
73	Sick sinus syndrome 4	Enrichment	GNB2	2.13
74	Thrombocytopenia 8, with dysmorphic features and developmental delay	Enrichment	ACTB	2.13
75	Myopathy, distal, 6, adult-onset, autosomal dominant	Enrichment	ACTN2	2.13
76	Congenital myopathy 14	Enrichment	MYL1	2.13
77	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.13
78	Whim syndrome 2	Enrichment	CXCR2	2.13
79	Baraitser-winter syndrome	Enrichment	ACTB	2.13
80	Capillary hemangioma	Enrichment	AKT3	2.13
81	Aquagenic palmoplantar keratoderma	Enrichment	CFTR	2.13
82	Autosomal dominant nonsyndromic hearing loss 17	Enrichment	MYH9	2.13
83	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.13
84	Congenital smooth muscle hamartoma	Enrichment	ACTB	2.13
85	Capillary leak syndrome	Enrichment	TLN1	2.13
86	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.13
87	Autosomal recessive severe congenital neutropenia due to cxcr2 deficiency	Enrichment	CXCR2	2.13
88	Developmental malformations-deafness-dystonia syndrome	Enrichment	ACTB	2.13
89	Gnao1-related disorder	Enrichment	GNAO1	2.13
90	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.13
91	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.13
92	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.13
93	Heart, malformation of	Enrichment	MAPK1, MYH6	2.12
94	Thrombocytopenia	Enrichment	MYH9, SRC, WAS	2.06
95	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.05
96	Granulomatous disease, chronic, autosomal recessive, 4	Enrichment	CYBA	2.05
97	Thrombocytopenia 1	Enrichment	WAS	2.05
98	Immunodeficiency 34	Enrichment	CYBB	2.05
99	Noonan syndrome 5	Enrichment	RAF1	2.05
100	Melorheostosis, isolated	Enrichment	MAP2K1	2.05
101	Deafness, autosomal dominant 1, with or without thrombocytopenia	Enrichment	DIAPH1	2.05
102	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.05
103	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.05
104	Amyotrophic lateral sclerosis 18	Enrichment	PFN1	2.05
105	46,xy sex reversal 6	Enrichment	MAP3K1	2.05
106	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.05
107	Melorheostosis	Enrichment	MAP2K1	2.05
108	Leopard syndrome 2	Enrichment	RAF1	2.05
109	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.05
110	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.05
111	Long qt syndrome 16	Enrichment	CALM3	2.05
112	Thrombocytopenia 6	Enrichment	SRC	2.05
113	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.05
114	Was-related disorders	Enrichment	WAS	2.05
115	Seizures, cortical blindness, and microcephaly syndrome	Enrichment	DIAPH1	2.05
116	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.05
117	Diaph1-related sensorineural hearing loss-thrombocytopenia syndrome	Enrichment	DIAPH1	2.05
118	Neurodevelopmental disorder with language delay and seizures	Enrichment	TIAM1	2.05
119	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.05
120	Trigonitis	Enrichment	RAF1	2.05
121	Long qt syndrome 15	Enrichment	CALM2	2.05
122	Autoinflammation with pulmonary and cutaneous vasculitis	Enrichment	HCK	2.05
123	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.05
124	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.05
125	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.05
126	Human immunodeficiency virus type 1	Enrichment	CCL11, CCL5	1.97
127	Aortic aneurysm, familial thoracic 4	Enrichment	MYH11	1.83
128	Leukocyte adhesion deficiency, type i	Enrichment	ITGB2	1.83
129	Arthrogryposis, distal, type 2a	Enrichment	MYH3	1.83
130	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	1.83
131	Spermatogenic failure, y-linked, 2	Enrichment	CFTR	1.83
132	Ebstein anomaly	Enrichment	MYH7	1.83
133	Cataract 35	Enrichment	MYH9	1.83
134	Lethal congenital contracture syndrome 3	Enrichment	PIP5K1C	1.83
135	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	1.83
136	Arthrogryposis, distal, type 7	Enrichment	MYH8	1.83
137	Deafness, autosomal dominant 20	Enrichment	ACTG1	1.83
138	Leukocyte adhesion deficiency, type iii	Enrichment	ITGB2	1.83
139	Baraitser-winter syndrome 2	Enrichment	ACTG1	1.83
140	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	1.83
141	Arthrogryposis, distal, type 2b3	Enrichment	MYH3	1.83
142	Megacystis-microcolon-intestinal hypoperistalsis syndrome 2	Enrichment	MYH11	1.83
143	Genitourinary and/or brain malformation syndrome	Enrichment	PPP1R12A	1.83
144	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	1.83
145	Developmental delay, language impairment, and ocular abnormalities	Enrichment	ARPC4	1.83
146	Atrial septal defect 3	Enrichment	MYH6	1.83
147	Noonan syndrome-like disorder with loose anagen hair	Enrichment	PPP1CB	1.83
148	Senior-loken syndrome 7	Enrichment	AKT3	1.83
149	Cardiomyopathy, familial hypertrophic, 10	Enrichment	MYL2	1.83
150	Intellectual developmental disorder, autosomal dominant 60, with seizures	Enrichment	PIP5K1A	1.83
151	Immunodeficiency 113 with autoimmunity and autoinflammation	Enrichment	ARPC5	1.83
152	Hereditary inclusion body myopathy-joint contractures-ophthalmoplegia syndrome	Enrichment	MYH2	1.83
153	Pseudosarcomatous fibromatosis	Enrichment	MYH9	1.83
154	Visceral myopathy 2	Enrichment	MYH11	1.83
155	Myopathy, myofibrillar, 12, infantile-onset, with cardiomyopathy	Enrichment	MYL2	1.83
156	Bardet-biedl syndrome 16	Enrichment	AKT3	1.83
157	Hypopituitarism	Enrichment	GNAI2	1.83
158	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	1.83
159	Arthrogryposis, distal, type 1c	Enrichment	MYL11	1.83
160	Megacystis-microcolon-intestinal hypoperistalsis syndrome 4	Enrichment	MYL9	1.83
161	Immunodeficiency 133	Enrichment	ARPC5	1.83
162	Childhood-onset autosomal recessive myopathy with external ophthalmoplegia	Enrichment	MYH2	1.83
163	Cerebral visual impairment	Enrichment	GNB1	1.83
164	Carney complex - trismus - pseudocamptodactyly syndrome	Enrichment	MYH8	1.83
165	Spinocerebellar ataxia 29	Enrichment	ITPR1	1.75
166	Costello syndrome	Enrichment	HRAS	1.75
167	Granulomatous disease, chronic, autosomal recessive, 1	Enrichment	NCF1	1.75
168	Neutropenia, severe congenital, x-linked	Enrichment	WAS	1.75
169	Wiskott-aldrich syndrome	Enrichment	WAS	1.75
170	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	1.75
171	Long qt syndrome 14	Enrichment	CALM1	1.75
172	Tafro syndrome	Enrichment	MAP2K2	1.75
173	Wooly hair nevus	Enrichment	HRAS	1.75
174	Macrothrombocytopenia and granulocyte inclusions with or without nephritis or sensorineural hearing loss	Enrichment	MYH9	1.66
175	Nuchal bleb, familial	Enrichment	CFTR	1.66
176	Spondylocarpotarsal synostosis syndrome	Enrichment	MYH3	1.66
177	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.66
178	Microcephaly, progressive, with seizures and cerebral and cerebellar atrophy	Enrichment	MYH15	1.66
179	Intrinsic cardiomyopathy	Enrichment	ACTN2	1.66
180	Qualitative or quantitative defects of beta-myosin heavy chain	Enrichment	MYH7	1.66
181	Idiopathic camptocormia	Enrichment	MYH7	1.66
182	Tricuspid valve insufficiency	Enrichment	MYH11	1.66
183	Autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia	Enrichment	CYBA	1.58
184	Gillespie syndrome	Enrichment	ITPR1	1.58
185	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.58
186	Large congenital melanocytic nevus	Enrichment	HRAS	1.58
187	Spermatocytoma	Enrichment	HRAS	1.58
188	Autoimmune polyendocrine syndrome type 1	Enrichment	CYBA	1.58
189	Left ventricular noncompaction	Enrichment	ACTN2, MYH7	1.56
190	Non-syndromic genetic deafness	Enrichment	ACTG1, MYH14	1.54
191	Myopathy, distal, 1	Enrichment	MYH7	1.54
192	Congenital myopathy 7b, myosin storage, autosomal recessive	Enrichment	MYH7	1.54
193	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.54
194	Auriculocondylar syndrome 1	Enrichment	GNAI3	1.54
195	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.54
196	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3	1.54
197	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.54
198	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3	1.54
199	Carney complex variant	Enrichment	MYH8	1.54
200	Congenital myopathy 7a, myosin storage, autosomal dominant	Enrichment	MYH7	1.54
201	Congenital myopathy 6 with ophthalmoplegia	Enrichment	MYH2	1.54
202	Aminoacylase 1 deficiency	Enrichment	ACTB	1.54
203	Achromatopsia 4	Enrichment	GNAI3	1.54
204	Contractures, pterygia, and spondylocarpotarsal fusion syndrome 1b	Enrichment	MYH3	1.54
205	Hyaline body myopathy	Enrichment	MYH7	1.54
206	Idiopathic bronchiectasis	Enrichment	CFTR	1.54
207	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	MYH11	1.54
208	Cerebral malaria	Enrichment	ICAM1	1.54
209	Mitral valve insufficiency	Enrichment	MYH11	1.54
210	Pseudomyogenic hemangioendothelioma	Enrichment	ACTB	1.54
211	Rare genetic deafness	Enrichment	ACTG1, DIAPH1, MYH9	1.48
212	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	1.46
213	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.46
214	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.46
215	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.46
216	Epidermolytic nevus	Enrichment	HRAS	1.46
217	Myopathy	Enrichment	MYH2, MYH7	1.46
218	Arthrogryposis, distal, type 2b1	Enrichment	MYH3	1.44
219	Congenital myopathy 3 with rigid spine	Enrichment	MYH7	1.44
220	Deafness, autosomal recessive 63	Enrichment	MYH9	1.44
221	Congenital ptosis	Enrichment	MYH10	1.44
222	Hemimegalencephaly	Enrichment	AKT3	1.44
223	Coloboma of choroid and retina	Enrichment	ACTG1	1.44
224	Distal arthrogryposis	Enrichment	MYH3, MYL11	1.42
225	Nonsyndromic hearing loss	Enrichment	ACTG1, MYH14	1.42
226	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MYH11, MYLK	1.38
227	Hemangioma, capillary infantile	Enrichment	MYH9	1.36
228	Intestinal pseudo-obstruction	Enrichment	MYH11	1.36
229	Breast adenocarcinoma	Enrichment	AKT1	1.36
230	Inherited arrhythmogenic cardiomyopathy	Enrichment	MYH7	1.36
231	Typical nemaline myopathy	Enrichment	CFL2	1.36
232	Megacolon	Enrichment	AKT3	1.30
233	Familial isolated restrictive cardiomyopathy	Enrichment	MYL2	1.30
234	Hemihyperplasia, isolated	Enrichment	RHOA	1.28
235	Moyamoya disease 1	Enrichment	DIAPH1	1.28
236	Pendred syndrome	Enrichment	DIAPH1	1.28
237	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.28
238	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.28
239	Arthrogryposis, distal, type 1a	Enrichment	MYH3	1.24
240	Hypothyroidism	Enrichment	GNB1	1.24
241	Myocarditis	Enrichment	MYH7	1.24
242	Choreatic disease	Enrichment	GNAO1	1.24
243	Hypoplastic left heart syndrome	Enrichment	MYH6	1.24
244	Nevus, epidermal	Enrichment	HRAS	1.22
245	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS	1.22
246	Myelofibrosis	Enrichment	SRC	1.22
247	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1	1.22
248	Pilomyxoid astrocytoma	Enrichment	RAF1	1.22
249	Follicular thyroid carcinoma	Enrichment	HRAS	1.22
250	Bronchiectasis with or without elevated sweat chloride 1	Enrichment	CFTR	1.19
251	Vas deferens, congenital bilateral aplasia of	Enrichment	CFTR	1.19
252	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.19
253	Cowden syndrome	Enrichment	AKT1	1.19
254	Familial isolated arrhythmogenic right ventricular dysplasia	Enrichment	MYH7	1.19
255	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.16
256	Cat eye syndrome	Enrichment	ACTG1	1.15
257	Polymicrogyria	Enrichment	AKT3	1.15
258	Autosomal dominant macrothrombocytopenia	Enrichment	ACTN1	1.15
259	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.11
260	Myelodysplastic syndrome	Enrichment	GNB1	1.11
261	Combined immunodeficiency	Enrichment	ARPC1B	1.11
262	Movement disease	Enrichment	GNAO1	1.11
263	Combined t cell and b cell immunodeficiency	Enrichment	ARPC1B	1.11
264	Specific learning disability	Enrichment	MAPK1	1.11
265	Combined t and b cell immunodeficiency	Enrichment	ARPC1B	1.11
266	Meningioma	Enrichment	AKT1	1.07
267	Restrictive cardiomyopathy	Enrichment	MYH7	1.07
268	Microphthalmia/coloboma 12	Enrichment	MYH10	1.04
269	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.04
270	Asthma	Enrichment	CCL11	1.03
271	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.03
272	Complex neurodevelopmental disorder	Enrichment	GNB2, MYH10, TIAM1	1.01
273	Heart disease	Enrichment	MYL2	1.01
274	Hereditary chronic pancreatitis	Enrichment	CFTR	1.01
275	Lip and oral cavity carcinoma	Enrichment	HRAS	0.99
276	Congenital long qt syndrome	Enrichment	ITPR3	0.99
277	Coloboma of macula	Enrichment	MYH10	0.98
278	Myopia	Enrichment	MYH11	0.98
279	Lynch syndrome	Enrichment	CFTR	0.98
280	Rare genetic intellectual disability	Enrichment	GNAO1	0.98
281	Breast cancer	Enrichment	AKT1, GNG3	0.98
282	Wolff-parkinson-white syndrome	Enrichment	MYH7	0.95
283	Arrhythmogenic right ventricular cardiomyopathy	Enrichment	ACTN2	0.95
284	Hypertension	Enrichment	MYH9	0.95
285	Multiple sclerosis	Enrichment	ITPR1	0.93
286	Osteoporosis	Enrichment	SRC	0.93
287	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1	0.93
288	Hypertension, essential	Enrichment	GNB3	0.93
289	Pancreatitis, hereditary	Enrichment	CFTR	0.93
290	Cleft palate, isolated	Enrichment	GNB1	0.93
291	Dandy-walker syndrome	Enrichment	PPP1CB	0.93
292	Neuromuscular disease	Enrichment	MYH7	0.90
293	Patent foramen ovale	Enrichment	MYH6	0.90
294	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	0.90
295	Anterior segment dysgenesis	Enrichment	ITPR1	0.90
296	Congenital myopathy	Enrichment	MYH7	0.88
297	Rhabdomyosarcoma	Enrichment	HRAS	0.88
298	Williams-beuren syndrome	Enrichment	LIMK1	0.86
299	Sudden infant death syndrome	Enrichment	CALM2	0.85
300	Lissencephaly	Enrichment	ACTG1	0.84
301	Centronuclear myopathy	Enrichment	CFL2	0.84
302	Attention deficit-hyperactivity disorder	Enrichment	GNB5	0.82
303	Malaria	Enrichment	ICAM1	0.81
304	Congenital stationary night blindness	Enrichment	GNB3	0.81
305	Familial atrial fibrillation	Enrichment	MYL4	0.79
306	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	0.77
307	Strabismus	Enrichment	GNB1	0.74
308	Congenital nervous system abnormality	Enrichment	GNAO1, GNB5	0.74
309	Nervous system disease	Enrichment	GNAO1, GNB5	0.74
310	Hydrops fetalis, nonimmune	Enrichment	HRAS	0.69
311	Auditory neuropathy	Enrichment	DIAPH1	0.69
312	Cystic fibrosis	Enrichment	CFTR	0.68
313	Male infertility	Enrichment	CFTR	0.65
314	Cakut	Enrichment	ACTG1	0.65
315	Genetic steroid-resistant nephrotic syndrome	Enrichment	ACTN4	0.65
316	Bladder cancer	Enrichment	HRAS	0.64
317	Differentiated thyroid carcinoma	Enrichment	HRAS	0.64
318	Dystonia	Enrichment	GNB1	0.64
319	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.63
320	Non-immune hydrops fetalis	Enrichment	HRAS	0.62
321	Autism spectrum disorder	Enrichment	GNB1, MAP2K1	0.60
322	Cerebral palsy	Enrichment	GNB1	0.60
323	Type 2 diabetes mellitus	Enrichment	AKT2	0.57
324	West syndrome	Enrichment	GNAO1	0.56
325	Hereditary breast carcinoma	Enrichment	AKT1	0.56
326	Epilepsy	Enrichment	DIAPH1	0.52
327	Body mass index quantitative trait locus 11	Enrichment	MYH9	0.51
328	Autosomal dominant non-syndromic intellectual disability	Enrichment	GNB1	0.51
329	Hypertelorism	Enrichment	MYH10	0.50
330	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	CFTR	0.47
331	Undetermined early-onset epileptic encephalopathy	Enrichment	LIMK1	0.47
332	Deafness, autosomal recessive	Enrichment	MYH9	0.43
333	Spastic ataxia	Enrichment	ITPR1	0.42
334	Autosomal recessive nonsyndromic deafness	Enrichment	MYH9	0.42
335	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	PFN1	0.39
336	Colorectal cancer	Enrichment	AKT1	0.32
337	Rare autosomal recessive non-syndromic sensorineural deafness type dfnb	Enrichment	MYH9	0.32
338	Ovarian cancer	Enrichment	AKT1	0.28

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Immune response CCR3 signaling in eosinophils

Pathway Network for Immune response CCR3 signaling in eosinophils

Member Pathways for Immune response CCR3 signaling in eosinophils

Pathways in the Immune response CCR3 signaling in eosinophils SuperPath

Associated Genes for Immune response CCR3 signaling in eosinophils

Associated Disorders for Immune response CCR3 signaling in eosinophils

Disorders associated with Immune response CCR3 signaling in eosinophils SuperPath

STRING Interaction Network for Immune response CCR3 signaling in eosinophils

Sources for Immune response CCR3 signaling in eosinophils