Immune response Function of MEF2 in T lymphocytes

Pathway network for the Immune response Function of MEF2 in T lymphocytes SuperPath

Sources:

GeneGo (Thomson Reuters)
QIAGEN
Reactome

Pathways in the Immune response Function of MEF2 in T lymphocytes SuperPath

#	Name	Source	Genes
1	Immune response Function of MEF2 in T lymphocytes	GeneGo (Thomson Reuters)	CABIN1 CALM1 CALM2 CALM3 CAMK1 CAMK4 CAMKK1 CAMKK2 CARM1 CD247 CD3D CD3E CD3G EP300 HDAC1 HDAC2 HDAC4 HDAC5 HDAC7 HDAC9 IL2 ITPR1 ITPR2 ITPR3 JUN KAT2B LAT LCK MAP2K5 MAP2K6 MAP3K2 MAP3K3 MAPK11 MAPK14 MAPK7 MEF2A MEF2B MEF2C MEF2D NCOA2 NFATC2 NR4A1 PLCG1 PPP3CA PPP3CB PPP3CC PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCI PRKCQ PRKCZ PRKD1 PRKD2 PRKD3 SFN SIN3A TRA TRAC TRAJ18 TRAV24 TRB TRBV11-1 TRBV11-2 TRBV11-3 TRBV17 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ ZAP70 (see all 76) (see less)
2	Development Role of HDAC and calcium/calmodulin-dependent kinase (CaMK) in control of skeletal myogenesis	GeneGo (Thomson Reuters)	AKT1 AKT2 AKT3 AMPD1 CACNA1C CALM1 CALM2 CALM3 CAMK4 CAMKK1 CAMKK2 CARM1 CDKN1A CPT1B EP300 HDAC4 HDAC5 HDAC7 HDAC9 IGF1 IGF1R IGF2 IRS1 JUN KAT2B MAP2K5 MAP2K6 MAP3K2 MAP3K3 MAPK11 MAPK14 MAPK7 MEF2A MEF2B MEF2C MEF2D MTOR MYF6 MYOD1 MYOG NCOA2 NFATC2 PDPK1 PGAM2 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 RHEB RPS6KB1 SFN TSC2 YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 65) (see less)
3	Calcium Mediated T-Cell Apoptosis	QIAGEN	ATP2A1 ATP2A2 ATP2A3 CABIN1 CALM1 CALM2 CALM3 CAPN2 CD247 CD3D CD3E CD3G CD4 EP300 FYN HDAC1 HDAC2 HLA-DMA HLA-DMB HLA-DOA HLA-DOB HLA-DPA1 HLA-DQA1 HLA-DQA2 HLA-DQB1 HLA-DRA HLA-DRB1 HLA-DRB3 HLA-DRB4 HLA-DRB5 ITPR1 ITPR2 ITPR3 LCK MEF2D NFATC2 NR4A1 PLCG1 PPP3CA PPP3CB PPP3CC PPP3R1 PPP3R2 PRKCA PRKCB PRKCD PRKCE PRKCG PRKCH PRKCQ PRKD1 PRKD3 (see all 52) (see less)
4	SARS-CoV-2 targets host intracellular signalling and regulatory pathways	Reactome	AKT1 AKT2 AKT3 CAV1 PDPK1 SFN YWHAB YWHAE YWHAG YWHAH YWHAQ YWHAZ (see all 12) (see less)

Gene overlap in member pathways for Immune response Function of MEF2 in T lymphocytes SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CALM1	Calmodulin 1	Protein Coding	3
2	CALM2	Calmodulin 2	Protein Coding	3
3	CALM3	Calmodulin 3	Protein Coding	3
4	EP300	EP300 Lysine Acetyltransferase	Protein Coding	3
5	SFN	Stratifin	Protein Coding	3
6	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	3
7	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	3
8	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	3
9	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	3
10	PPP3CC	Protein Phosphatase 3 Catalytic Subunit Gamma	Protein Coding	3
11	YWHAB	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Beta	Protein Coding	3
12	YWHAE	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Epsilon	Protein Coding	3
13	YWHAG	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Gamma	Protein Coding	3
14	YWHAH	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Eta	Protein Coding	3
15	YWHAZ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Zeta	Protein Coding	3
16	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	3
17	CAMK4	Calcium/Calmodulin Dependent Protein Kinase IV	Protein Coding	2
18	CD3D	CD3 Delta Subunit Of T-Cell Receptor Complex	Protein Coding	2
19	CD3E	CD3 Epsilon Subunit Of T-Cell Receptor Complex	Protein Coding	2
20	CD3G	CD3 Gamma Subunit Of T-Cell Receptor Complex	Protein Coding	2
21	CD247	CD247 Molecule	Protein Coding	2
22	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
23	HDAC1	Histone Deacetylase 1	Protein Coding	2
24	HDAC2	Histone Deacetylase 2	Protein Coding	2
25	NR4A1	Nuclear Receptor Subfamily 4 Group A Member 1	Protein Coding	2
26	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	2
27	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	2
28	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	2
29	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	2
30	LCK	LCK Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	2
31	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	2
32	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	2
33	MAP3K3	Mitogen-Activated Protein Kinase Kinase Kinase 3	Protein Coding	2
34	PLCG1	Phospholipase C Gamma 1	Protein Coding	2
35	PRKCA	Protein Kinase C Alpha	Protein Coding	2
36	PRKCB	Protein Kinase C Beta	Protein Coding	2
37	PRKCD	Protein Kinase C Delta	Protein Coding	2
38	PRKCE	Protein Kinase C Epsilon	Protein Coding	2
39	PRKCG	Protein Kinase C Gamma	Protein Coding	2
40	PRKCH	Protein Kinase C Eta	Protein Coding	2
41	PRKD1	Protein Kinase D1	Protein Coding	2
42	PRKCQ	Protein Kinase C Theta	Protein Coding	2
43	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	2
44	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	2
45	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	2
46	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	2
47	KAT2B	Lysine Acetyltransferase 2B	Protein Coding	2
48	HDAC9	Histone Deacetylase 9	Protein Coding	2
49	HDAC4	Histone Deacetylase 4	Protein Coding	2
50	HDAC5	Histone Deacetylase 5	Protein Coding	2
51	CARM1	Coactivator Associated Arginine Methyltransferase 1	Protein Coding	2
52	NCOA2	Nuclear Receptor Coactivator 2	Protein Coding	2
53	CAMKK2	Calcium/Calmodulin Dependent Protein Kinase Kinase 2	Protein Coding	2
54	MAP3K2	Mitogen-Activated Protein Kinase Kinase Kinase 2	Protein Coding	2
55	CABIN1	Calcineurin Binding Protein 1	Protein Coding	2
56	PRKD3	Protein Kinase D3	Protein Coding	2
57	HDAC7	Histone Deacetylase 7	Protein Coding	2
58	CAMKK1	Calcium/Calmodulin Dependent Protein Kinase Kinase 1	Protein Coding	2
59	MEF2B	Myocyte Enhancer Factor 2B	Protein Coding	2
60	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
61	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
62	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
63	PPP3R1	Protein Phosphatase 3 Regulatory Subunit B, Alpha	Protein Coding	2
64	PPP3R2	Protein Phosphatase 3 Regulatory Subunit B, Beta	Protein Coding	2
65	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	2
66	IL2	Interleukin 2	Protein Coding	1
67	PRKCI	Protein Kinase C Iota	Protein Coding	1
68	PRKCZ	Protein Kinase C Zeta	Protein Coding	1
69	TRA	T Cell Receptor Alpha Locus	Protein Coding	1
70	TRB	T Cell Receptor Beta Locus	Protein Coding	1
71	ZAP70	Zeta Chain Of T Cell Receptor Associated Protein Kinase 70	Protein Coding	1
72	CAMK1	Calcium/Calmodulin Dependent Protein Kinase I	Protein Coding	1
73	PRKD2	Protein Kinase D2	Protein Coding	1
74	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
75	LAT	Linker For Activation Of T Cells	Protein Coding	1
76	TRBV17	T Cell Receptor Beta Variable 17 (Non-Functional)	Protein Coding	1
77	TRBV11-3	T Cell Receptor Beta Variable 11-3	Protein Coding	1
78	TRBV11-2	T Cell Receptor Beta Variable 11-2	Protein Coding	1
79	TRBV11-1	T Cell Receptor Beta Variable 11-1	Protein Coding	1
80	TRAV24	T Cell Receptor Alpha Variable 24	Protein Coding	1
81	TRAJ18	T Cell Receptor Alpha Joining 18	Protein Coding	1
82	TRAC	T Cell Receptor Alpha Constant	Protein Coding	1
83	AMPD1	Adenosine Monophosphate Deaminase 1	Protein Coding	1
84	CACNA1C	Calcium Voltage-Gated Channel Subunit Alpha1 C	Protein Coding	1
85	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
86	CPT1B	Carnitine Palmitoyltransferase 1B	Protein Coding	1
87	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
88	IGF1	Insulin Like Growth Factor 1	Protein Coding	1
89	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
90	IGF2	Insulin Like Growth Factor 2	Protein Coding	1
91	IRS1	Insulin Receptor Substrate 1	Protein Coding	1
92	MYF6	Myogenic Factor 6	Protein Coding	1
93	MYOD1	Myogenic Differentiation 1	Protein Coding	1
94	MYOG	Myogenin	Protein Coding	1
95	PGAM2	Phosphoglycerate Mutase 2	Protein Coding	1
96	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
97	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
98	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
99	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
100	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
101	RHEB	Ras Homolog, MTORC1 Binding	Protein Coding	1
102	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	1
103	TSC2	TSC Complex Subunit 2	Protein Coding	1
104	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
105	ATP2A1	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 1	Protein Coding	1
106	ATP2A2	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 2	Protein Coding	1
107	ATP2A3	ATPase Sarcoplasmic/Endoplasmic Reticulum Ca2+ Transporting 3	Protein Coding	1
108	CAPN2	Calpain 2	Protein Coding	1
109	CD4	CD4 Molecule	Protein Coding	1
110	FYN	FYN Proto-Oncogene, Src Family Tyrosine Kinase	Protein Coding	1
111	HLA-DMA	Major Histocompatibility Complex, Class II, DM Alpha	Protein Coding	1
112	HLA-DMB	Major Histocompatibility Complex, Class II, DM Beta	Protein Coding	1
113	HLA-DOA	Major Histocompatibility Complex, Class II, DO Alpha	Protein Coding	1
114	HLA-DOB	Major Histocompatibility Complex, Class II, DO Beta	Protein Coding	1
115	HLA-DPA1	Major Histocompatibility Complex, Class II, DP Alpha 1	Protein Coding	1
116	HLA-DQA1	Major Histocompatibility Complex, Class II, DQ Alpha 1	Protein Coding	1
117	HLA-DQA2	Major Histocompatibility Complex, Class II, DQ Alpha 2	Protein Coding	1
118	HLA-DQB1	Major Histocompatibility Complex, Class II, DQ Beta 1	Protein Coding	1
119	HLA-DRA	Major Histocompatibility Complex, Class II, DR Alpha	Protein Coding	1
120	HLA-DRB1	Major Histocompatibility Complex, Class II, DR Beta 1	Protein Coding	1
121	HLA-DRB3	Major Histocompatibility Complex, Class II, DR Beta 3	Protein Coding	1
122	HLA-DRB4	Major Histocompatibility Complex, Class II, DR Beta 4	Protein Coding	1
123	HLA-DRB5	Major Histocompatibility Complex, Class II, DR Beta 5	Protein Coding	1
124	CAV1	Caveolin 1	Protein Coding	1

Disorders associated with Immune response Function of MEF2 in T lymphocytes SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Covid-19	Direct
2	Hemimegalencephaly	Enrichment	AKT3, MTOR, PIK3CA, RHEB	8.62
3	Severe combined immunodeficiency	Enrichment	CD247, CD3D, CD3E, CD3G, LCK, ZAP70	7.60
4	T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zeta	Enrichment	CD247, CD3D, CD3E	7.27
5	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	6.38
6	Focal cortical dysplasia, type ii	Enrichment	MTOR, RHEB, TSC2	6.38
7	Isolated focal cortical dysplasia type ii	Enrichment	MTOR, RHEB, TSC2	6.38
8	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	5.53
9	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3	5.31
10	Celiac disease 1	Enrichment	HLA-DQA1, HLA-DQB1	4.84
11	Bullous pemphigoid	Enrichment	HLA-DQB1, HLA-DRB1	4.84
12	Pediatric multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1	4.84
13	Multiple sclerosis	Enrichment	HLA-DQB1, HLA-DRB1, ITPR1	4.73
14	Colorectal cancer	Enrichment	AKT1, EP300, IGF2, PIK3CA, PIK3R1	4.23
15	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.17
16	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	4.17
17	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	4.17
18	Idiopathic achalasia	Enrichment	HLA-DQA1, HLA-DQB1	4.07
19	Immunodeficiency 7	Enrichment	TRA, TRAC	4.03
20	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	3.87
21	Narcolepsy 2	Enrichment	HLA-DQB1, HLA-DRB1	3.84
22	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	3.65
23	Myopathy, centronuclear, 1	Enrichment	MYF6, MYOD1	3.48
24	Hemihyperplasia, isolated	Enrichment	IGF2, PIK3CA	3.48
25	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.48
26	Narcolepsy 1	Enrichment	HLA-DQB1, HLA-DRB1	3.40
27	Long qt syndrome	Enrichment	CACNA1C, CALM1, CALM2	3.37
28	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	3.33
29	Adult hepatocellular carcinoma	Enrichment	PIK3CA, TSC2	3.10
30	Cowden syndrome	Enrichment	AKT1, PIK3CA	3.10
31	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	3.00
32	Meningioma	Enrichment	AKT1, PIK3CA	2.84
33	Nk-cell enteropathy	Enrichment	IGF1R, PIK3CB	2.77
34	Rare genetic intellectual disability	Enrichment	EP300, MTOR	2.64
35	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.42
36	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.42
37	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.42
38	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.42
39	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.42
40	Okt4 epitope deficiency	Enrichment	CD4	2.42
41	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.42
42	Immunodeficiency 18	Enrichment	CD3E	2.42
43	Pulmonary alveolar proteinosis, acquired	Enrichment	HLA-DRB1	2.42
44	Immunodeficiency 25	Enrichment	CD247	2.42
45	Spinocerebellar ataxia 14	Enrichment	PRKCG	2.42
46	Long qt syndrome 16	Enrichment	CALM3	2.42
47	Graham little-piccardi-lassueur syndrome	Enrichment	HLA-DRA	2.42
48	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.42
49	Immunodeficiency 22	Enrichment	LCK	2.42
50	Immunodeficiency 79	Enrichment	CD4	2.42
51	Immunodeficiency 19, severe combined	Enrichment	CD3D	2.42
52	Long qt syndrome 15	Enrichment	CALM2	2.42
53	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.42
54	Rhabdomyolysis 2	Enrichment	ATP2A2	2.42
55	Immunodeficiency 19	Enrichment	CD3D	2.42
56	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.42
57	Macrodactyly	Enrichment	PIK3CA	2.32
58	Proteus syndrome	Enrichment	AKT1	2.32
59	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.32
60	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.32
61	Cowden syndrome 5	Enrichment	PIK3CA	2.32
62	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.32
63	Chromosome 2q37 deletion syndrome	Enrichment	HDAC4	2.32
64	Auriculocondylar syndrome 4	Enrichment	HDAC9	2.32
65	Short syndrome	Enrichment	PIK3R1	2.32
66	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.32
67	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.32
68	Brugada syndrome 3	Enrichment	CACNA1C	2.32
69	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.32
70	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.32
71	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.32
72	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.32
73	Cowden syndrome 6	Enrichment	AKT1	2.32
74	Congenital myopathy 17	Enrichment	MYOD1	2.32
75	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.32
76	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.32
77	Developmental and epileptic encephalopathy 56	Enrichment	YWHAG	2.32
78	Myopathy due to myoadenylate deaminase deficiency	Enrichment	AMPD1	2.32
79	Neurodevelopmental disorder with central hypotonia and dysmorphic facies	Enrichment	HDAC4	2.32
80	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.32
81	Hypospadias	Enrichment	PIK3CA	2.32
82	Capillary hemangioma	Enrichment	AKT3	2.32
83	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.32
84	Cerebral cavernous malformations 5	Enrichment	MAP3K3	2.32
85	Rare venous malformation	Enrichment	PIK3CA	2.32
86	Diaphragmatic eventration	Enrichment	PIK3CA	2.32
87	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.32
88	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.32
89	Atypical timothy syndrome	Enrichment	CACNA1C	2.32
90	Rare combined vascular malformation	Enrichment	PIK3CA	2.32
91	Cavernous lymphangioma	Enrichment	PIK3CA	2.32
92	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.32
93	Timothy syndrome type 2	Enrichment	CACNA1C	2.32
94	Mef2c-related disorder	Enrichment	MEF2C	2.32
95	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.32
96	Verrucous hemangioma	Enrichment	MAP3K3	2.32
97	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.32
98	Timothy syndrome type 1	Enrichment	CACNA1C	2.32
99	Distal 17p13.3 microdeletion syndrome	Enrichment	YWHAE	2.32
100	Macrodactyly of toe	Enrichment	PIK3CA	2.32
101	Cacna1c-related disorders	Enrichment	CACNA1C	2.32
102	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.32
103	Breast cancer	Enrichment	AKT1, JUN, PIK3CA	2.26
104	Immunodeficiency 48	Enrichment	ZAP70	2.25
105	Autoimmune disease, multisystem, infantile-onset, 2	Enrichment	ZAP70	2.25
106	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.25
107	Zap70-related severe combined immunodeficiency	Enrichment	ZAP70	2.25
108	Precursor t-cell acute lymphoblastic leukemia	Enrichment	TRA, TRB	2.14
109	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.12
110	Acrokeratosis verruciformis	Enrichment	ATP2A2	2.12
111	Brody disease	Enrichment	ATP2A1	2.12
112	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.12
113	Creutzfeldt-jakob disease	Enrichment	HLA-DQB1	2.12
114	Sarcoidosis 1	Enrichment	HLA-DRB1	2.12
115	Long qt syndrome 14	Enrichment	CALM1	2.12
116	Menke-hennekam syndrome 2	Enrichment	EP300	2.12
117	Immunodeficiency 17	Enrichment	CD3G	2.12
118	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	2.12
119	Bladder cancer	Enrichment	CDKN1A, PIK3CA	2.07
120	Scoliosis, isolated 1	Enrichment	MAPK7	2.02
121	Timothy syndrome	Enrichment	CACNA1C	2.02
122	Lymphangioleiomyomatosis	Enrichment	TSC2	2.02
123	Keratosis, seborrheic	Enrichment	PIK3CA	2.02
124	Roifman-chitayat syndrome	Enrichment	PIK3CD	2.02
125	Silver-russell syndrome 3	Enrichment	IGF2	2.02
126	Noonan syndrome 8	Enrichment	PIK3CA	2.02
127	Long qt syndrome 8	Enrichment	CACNA1C	2.02
128	Cebalid syndrome	Enrichment	MTOR	2.02
129	Senior-loken syndrome 7	Enrichment	AKT3	2.02
130	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.02
131	Immune system disease	Enrichment	PIK3CD	2.02
132	Bardet-biedl syndrome 16	Enrichment	AKT3	2.02
133	Smith-kingsmore syndrome	Enrichment	MTOR	2.02
134	Adenosine monophosphate deaminase deficiency	Enrichment	AMPD1	2.02
135	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	2.02
136	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	2.02
137	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	2.02
138	Witteveen-kolk syndrome	Enrichment	SIN3A	1.95
139	Trypsinogen deficiency	Enrichment	TRB	1.95
140	Immunodeficiency 52	Enrichment	LAT	1.95
141	Darier-white disease	Enrichment	ATP2A2	1.94
142	Gillespie syndrome	Enrichment	ITPR1	1.94
143	Adult-onset myasthenia gravis	Enrichment	HLA-DQA1	1.94
144	Vogt-koyanagi-harada disease	Enrichment	HLA-DRB1	1.94
145	Ovarian cancer	Enrichment	AKT1, PIK3CA, TSC2	1.90
146	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.84
147	Tuberous sclerosis 1	Enrichment	TSC2	1.84
148	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	1.84
149	Tuberous sclerosis 2	Enrichment	TSC2	1.84
150	Miller-dieker lissencephaly syndrome	Enrichment	YWHAE	1.84
151	Chromosome 17p13.3, centromeric, duplication syndrome	Enrichment	YWHAE	1.84
152	Neurodevelopmental disorder with hypotonia, language delay, and skeletal defects with or without seizures	Enrichment	CACNA1C	1.84
153	Hamartoma	Enrichment	TSC2	1.84
154	Xanthinuria, type ii	Enrichment	TSC2	1.84
155	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.84
156	Keratoacanthoma	Enrichment	PIK3CA	1.84
157	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.84
158	Temporal arteritis	Enrichment	HLA-DRB1	1.82
159	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.82
160	Hereditary ataxia	Enrichment	PRKCG	1.82
161	Systemic-onset juvenile idiopathic arthritis	Enrichment	HLA-DRB1	1.82
162	Type 2 diabetes mellitus	Enrichment	AKT2, IRS1	1.76
163	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA	1.73
164	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.72
165	Follicular lymphoma	Enrichment	HLA-DRB1	1.72
166	Diffuse cutaneous systemic sclerosis	Enrichment	HLA-DRB1	1.72
167	Ventricular fibrillation, paroxysmal familial, 1	Enrichment	CACNA1C	1.72
168	Glycogen storage disease x	Enrichment	PGAM2	1.72
169	Tuberous sclerosis	Enrichment	TSC2	1.72
170	Cerebrovascular disease	Enrichment	PIK3CA	1.72
171	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	YWHAZ	1.72
172	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.72
173	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	1.72
174	Microcephaly	Enrichment	EP300, IGF1R, YWHAG	1.67
175	Rubinstein-taybi syndrome 1	Enrichment	EP300	1.64
176	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	EP300	1.64
177	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.64
178	Granulomatosis with polyangiitis	Enrichment	HLA-DPA1	1.64
179	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.64
180	Limited scleroderma	Enrichment	HLA-DRB1	1.64
181	Capillary malformations, congenital	Enrichment	PIK3CA	1.62
182	Heart conduction disease	Enrichment	CACNA1C	1.62
183	Endometrial stromal sarcoma	Enrichment	YWHAE	1.62
184	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA, YWHAZ	1.62
185	Oligoarticular juvenile idiopathic arthritis	Enrichment	CD247	1.58
186	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	CD247	1.58
187	Vitamin d-dependent rickets, type 2a	Enrichment	TRB	1.56
188	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.55
189	Cowden syndrome 1	Enrichment	PIK3CA	1.55
190	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.55
191	Kidney clear cell sarcoma	Enrichment	YWHAE	1.55
192	Myeloma, multiple	Enrichment	HDAC4, PIK3R2	1.53
193	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA, YWHAG	1.53
194	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.52
195	Nevus, epidermal	Enrichment	PIK3CA	1.48
196	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.48
197	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	1.48
198	Silver-russell syndrome 1	Enrichment	IGF2	1.48
199	Capillary malformation-arteriovenous malformation 1	Enrichment	PIK3CA	1.48
200	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.48
201	Polycystic kidney disease 1	Enrichment	TSC2	1.48
202	Gallbladder cancer	Enrichment	PIK3CA	1.48
203	Megacolon	Enrichment	AKT3	1.48
204	Charge syndrome	Enrichment	EP300	1.47
205	Inflammatory bowel disease 1	Enrichment	PRKCQ	1.47
206	Stroke, ischemic	Enrichment	PRKCH	1.42
207	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	CACNA1C	1.37
208	Arteriovenous malformation	Enrichment	PIK3CA	1.37
209	Congenital long qt syndrome	Enrichment	ITPR3	1.35
210	Myopathy, x-linked, with excessive autophagy	Enrichment	PIK3CA	1.33
211	Polymicrogyria	Enrichment	AKT3	1.33
212	Lung non-small cell carcinoma	Enrichment	PIK3CA	1.29
213	Specific learning disability	Enrichment	YWHAG	1.29
214	Polydactyly, postaxial, type a1	Enrichment	EP300	1.25
215	Anterior segment dysgenesis	Enrichment	ITPR1	1.25
216	Cardiac conduction defect	Enrichment	CACNA1C	1.25
217	Lip and oral cavity carcinoma	Enrichment	PIK3CA	1.25
218	Combined immunodeficiency	Enrichment	ZAP70	1.22
219	Combined t cell and b cell immunodeficiency	Enrichment	ZAP70	1.22
220	Combined t and b cell immunodeficiency	Enrichment	ZAP70	1.22
221	Sudden infant death syndrome	Enrichment	CALM2	1.20
222	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.16
223	Wilms tumor 1	Enrichment	IGF2	1.16
224	Lynch syndrome	Enrichment	PIK3CA	1.16
225	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.16
226	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.15
227	Hereditary chronic pancreatitis	Enrichment	TRB	1.12
228	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	1.11
229	Beckwith-wiedemann syndrome	Enrichment	IGF2	1.08
230	Pancreatitis, hereditary	Enrichment	TRB	1.04
231	Endometrial cancer	Enrichment	PIK3CA	1.02
232	Autism spectrum disorder	Enrichment	MEF2C, TSC2	1.02
233	Hepatocellular carcinoma	Enrichment	PIK3CA	1.00
234	Severe covid-19	Enrichment	HLA-DQB1	0.98
235	Cardiomyopathy, familial hypertrophic, 1	Enrichment	CACNA1C	0.96
236	Brugada syndrome	Enrichment	CACNA1C	0.93
237	Prostate cancer	Enrichment	PIK3CA	0.89
238	Systemic lupus erythematosus	Enrichment	HLA-DRB1	0.86
239	Lung cancer	Enrichment	PIK3CA	0.85
240	Fetal akinesia deformation sequence 1	Enrichment	MYOD1	0.79
241	Cerebral palsy	Enrichment	CACNA1C	0.77
242	Distal arthrogryposis	Enrichment	MYOD1	0.74
243	Spastic ataxia	Enrichment	ITPR1	0.73
244	Gastric cancer	Enrichment	PIK3CA	0.73
245	West syndrome	Enrichment	TSC2	0.72
246	Hypertelorism	Enrichment	PIK3CA	0.65
247	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MEF2C	0.61
248	Congenital nervous system abnormality	Enrichment	TSC2	0.40
249	Nervous system disease	Enrichment	TSC2	0.40
250	Complex neurodevelopmental disorder	Enrichment	CACNA1C	0.35
251	Inherited cancer-predisposing syndrome	Enrichment	TSC2	0.33

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Immune response Function of MEF2 in T lymphocytes

Pathway Network for Immune response Function of MEF2 in T lymphocytes

Pathway network for the Immune response Function of MEF2 in T lymphocytes SuperPath

Member Pathways for Immune response Function of MEF2 in T lymphocytes

Pathways in the Immune response Function of MEF2 in T lymphocytes SuperPath

Gene overlap in member pathways for Immune response Function of MEF2 in T lymphocytes SuperPath

Associated Genes for Immune response Function of MEF2 in T lymphocytes

Associated Disorders for Immune response Function of MEF2 in T lymphocytes

Disorders associated with Immune response Function of MEF2 in T lymphocytes SuperPath

STRING Interaction Network for Immune response Function of MEF2 in T lymphocytes

Sources for Immune response Function of MEF2 in T lymphocytes