Immune response_IFN gamma signaling pathway

No Pathway Network information available for Immune response_IFN gamma signaling pathway

Pathways in the Immune response_IFN gamma signaling pathway SuperPath

#	Name	Source	Genes
1	Immune response_IFN gamma signaling pathway	GeneGo (Thomson Reuters)	AFAP1 AKT1 AKT2 AKT3 ATF2 BRCA1 CALM1 CALM2 CALM3 CAMK2A CAMK2B CAMK2D CAMK2G CBL CDKN1A CEBPB CREBBP CRKL EIF2AK2 EP300 FANCC ICAM1 IFNG IFNGR1 IFNGR2 IRF1 IRF9 ITPR1 ITPR2 ITPR3 JAK1 JAK2 MAP2K1 MAP2K6 MAP3K1 MAP3K4 MAPK1 MAPK11 MAPK12 MAPK13 MAPK14 MAPK3 MCM5 MYC PDPK1 PIK3CA PIK3CB PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG2 PRKCA PRKCD PTK2B PTPN11 RAP1A RAPGEF1 SMAD7 SOCS1 SRC STAT1 STAT2 (see all 63) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
2	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1
3	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	1
4	CALM1	Calmodulin 1	Protein Coding	1
5	CALM2	Calmodulin 2	Protein Coding	1
6	CALM3	Calmodulin 3	Protein Coding	1
7	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	1
8	CAMK2B	Calcium/Calmodulin Dependent Protein Kinase II Beta	Protein Coding	1
9	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	1
10	CAMK2G	Calcium/Calmodulin Dependent Protein Kinase II Gamma	Protein Coding	1
11	CBL	Cbl Proto-Oncogene	Protein Coding	1
12	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
13	CEBPB	CCAAT Enhancer Binding Protein Beta	Protein Coding	1
14	ATF2	Activating Transcription Factor 2	Protein Coding	1
15	CREBBP	CREB Binding Lysine Acetyltransferase	Protein Coding	1
16	CRKL	CRK Like Proto-Oncogene, Adaptor Protein	Protein Coding	1
17	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
18	EP300	EP300 Lysine Acetyltransferase	Protein Coding	1
19	FANCC	FA Complementation Group C	Protein Coding	1
20	PTK2B	Protein Tyrosine Kinase 2 Beta	Protein Coding	1
21	RAPGEF1	Rap Guanine Nucleotide Exchange Factor 1	Protein Coding	1
22	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
23	IFNG	Interferon Gamma	Protein Coding	1
24	IFNGR1	Interferon Gamma Receptor 1	Protein Coding	1
25	IFNGR2	Interferon Gamma Receptor 2	Protein Coding	1
26	IRF1	Interferon Regulatory Factor 1	Protein Coding	1
27	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
28	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
29	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
30	JAK1	Janus Kinase 1	Protein Coding	1
31	JAK2	Janus Kinase 2	Protein Coding	1
32	SMAD7	SMAD Family Member 7	Protein Coding	1
33	MCM5	Minichromosome Maintenance Complex Component 5	Protein Coding	1
34	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
35	MAP3K4	Mitogen-Activated Protein Kinase Kinase Kinase 4	Protein Coding	1
36	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
37	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
38	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
39	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
40	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
41	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
42	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
43	PLCG2	Phospholipase C Gamma 2	Protein Coding	1
44	PRKCA	Protein Kinase C Alpha	Protein Coding	1
45	PRKCD	Protein Kinase C Delta	Protein Coding	1
46	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
47	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
48	MAPK11	Mitogen-Activated Protein Kinase 11	Protein Coding	1
49	MAPK13	Mitogen-Activated Protein Kinase 13	Protein Coding	1
50	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	1
51	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	1
52	EIF2AK2	Eukaryotic Translation Initiation Factor 2 Alpha Kinase 2	Protein Coding	1
53	PTPN11	Protein Tyrosine Phosphatase Non-Receptor Type 11	Protein Coding	1
54	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
55	MAPK12	Mitogen-Activated Protein Kinase 12	Protein Coding	1
56	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
57	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
58	STAT2	Signal Transducer And Activator Of Transcription 2	Protein Coding	1
59	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
60	SOCS1	Suppressor Of Cytokine Signaling 1	Protein Coding	1
61	AKT3	AKT Serine/Threonine Kinase 3	Protein Coding	1
62	IRF9	Interferon Regulatory Factor 9	Protein Coding	1
63	AFAP1	Actin Filament Associated Protein 1	Protein Coding	1

Disorders associated with Immune response_IFN gamma signaling pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Colorectal cancer	Enrichment	AKT1, BRCA1, EP300, FANCC, PIK3CA, PIK3R1, SRC	6.84
2	Long qt syndrome 1	Enrichment	CALM1, CALM2, CALM3, ITPR3, PTPN11	6.62
3	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	AKT3, PIK3CA, PIK3R2	6.42
4	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1, CALM2, CALM3	5.28
5	Lung non-small cell carcinoma	Enrichment	IRF1, MAP2K1, PIK3CA	4.81
6	Noonan syndrome and noonan-related syndrome	Enrichment	CBL, MAP2K1, PTPN11	4.38
7	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	4.20
8	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	4.20
9	Breast implant-associated anaplastic large cell lymphoma	Enrichment	JAK1, JAK2	4.20
10	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	4.20
11	Ovarian cancer	Enrichment	AKT1, BRCA1, FANCC, MAP3K1, PIK3CA	3.99
12	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	CRKL, MAPK1	3.90
13	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	AKT3, PIK3R2	3.90
14	Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	3.90
15	Noonan syndrome 1	Enrichment	CBL, MAP2K1, PTPN11	3.80
16	Myeloproliferative neoplasm	Enrichment	CBL, JAK2	3.68
17	Hemimegalencephaly	Enrichment	AKT3, PIK3CA	3.68
18	Rasopathy	Enrichment	CBL, MAP2K1, PTPN11	3.64
19	Rubinstein-taybi syndrome 1	Enrichment	CREBBP, EP300	3.50
20	Chromosome 16p13.3 deletion syndrome, proximal	Enrichment	CREBBP, EP300	3.50
21	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.50
22	Bladder cancer	Enrichment	BRCA1, CDKN1A, PIK3CA	3.49
23	Breast cancer	Enrichment	AKT1, BRCA1, FANCC, PIK3CA	3.40
24	Lung cancer	Enrichment	BRCA1, IRF1, PIK3CA	3.37
25	Myelofibrosis	Enrichment	JAK2, SRC	3.36
26	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	3.36
27	Arteriovenous malformation	Enrichment	MAP2K1, PIK3CA	3.13
28	Cowden syndrome	Enrichment	AKT1, PIK3CA	3.13
29	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1, PIK3CA	3.03
30	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	3.03
31	Gastric cancer	Enrichment	BRCA1, IRF1, PIK3CA	2.99
32	Hereditary breast carcinoma	Enrichment	AKT1, BRCA1, PIK3CA	2.96
33	Specific learning disability	Enrichment	MAPK1, PTPN11	2.94
34	Juvenile myelomonocytic leukemia	Enrichment	CBL, PTPN11	2.87
35	Meningioma	Enrichment	AKT1, PIK3CA	2.87
36	Congenital long qt syndrome	Enrichment	ITPR3, PTPN11	2.87
37	Rare genetic intellectual disability	Enrichment	CREBBP, EP300	2.67
38	Rhabdomyosarcoma	Enrichment	BRCA1, CBL	2.61
39	Microcephaly	Enrichment	CAMK2B, EP300, MAPK1, PTPN11	2.60
40	Diffuse large b-cell lymphoma	Enrichment	CREBBP, SOCS1	2.46
41	Endometrial cancer	Enrichment	BRCA1, PIK3CA	2.38
42	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.33
43	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.33
44	Macrodactyly	Enrichment	PIK3CA	2.33
45	Proteus syndrome	Enrichment	AKT1	2.33
46	Metachondromatosis	Enrichment	PTPN11	2.33
47	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.33
48	Helicobacter pylori infection	Enrichment	IFNGR1	2.33
49	Melorheostosis, isolated	Enrichment	MAP2K1	2.33
50	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.33
51	Leopard syndrome 1	Enrichment	PTPN11	2.33
52	Cowden syndrome 5	Enrichment	PIK3CA	2.33
53	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.33
54	46,xy sex reversal 6	Enrichment	MAP3K1	2.33
55	Autoimmune lymphoproliferative syndrome, type iii	Enrichment	PRKCD	2.33
56	Immunodeficiency 27a	Enrichment	IFNGR1	2.33
57	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.33
58	Immunodeficiency 69	Enrichment	IFNG	2.33
59	Pseudo-torch syndrome 3	Enrichment	STAT2	2.33
60	Noonan syndrome 13	Enrichment	MAPK1	2.33
61	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.33
62	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	2.33
63	Intellectual developmental disorder, autosomal dominant 54	Enrichment	CAMK2B	2.33
64	Leukoencephalopathy, developmental delay, and episodic neurologic regression syndrome	Enrichment	EIF2AK2	2.33
65	Short syndrome	Enrichment	PIK3R1	2.33
66	Infant-type hemispheric glioma	Enrichment	BRCA1	2.33
67	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 2	Enrichment	AKT3	2.33
68	Immunodeficiency 27b	Enrichment	IFNGR1	2.33
69	Meier-gorlin syndrome 8	Enrichment	MCM5	2.33
70	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.33
71	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.33
72	Melorheostosis	Enrichment	MAP2K1	2.33
73	Immunodeficiency 31a	Enrichment	STAT1	2.33
74	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.33
75	Autoinflammation, antibody deficiency, and immune dysregulation	Enrichment	PLCG2	2.33
76	Long qt syndrome 16	Enrichment	CALM3	2.33
77	Cowden syndrome 6	Enrichment	AKT1	2.33
78	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.33
79	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.33
80	Colorectal cancer 3	Enrichment	SMAD7	2.33
81	Immunodeficiency 31b	Enrichment	STAT1	2.33
82	Familial cold autoinflammatory syndrome 3	Enrichment	PLCG2	2.33
83	Thrombocytopenia 6	Enrichment	SRC	2.33
84	Dystonia 33	Enrichment	EIF2AK2	2.33
85	Menke-hennekam syndrome 1	Enrichment	CREBBP	2.33
86	Immunodeficiency 65 viral infections	Enrichment	IRF9	2.33
87	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	2.33
88	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.33
89	Intellectual developmental disorder, autosomal dominant 59	Enrichment	CAMK2G	2.33
90	Long qt syndrome 15	Enrichment	CALM2	2.33
91	Rubinstein-taybi syndrome due to 16p13.3 microdeletion	Enrichment	CREBBP	2.33
92	Hypospadias	Enrichment	PIK3CA	2.33
93	Capillary hemangioma	Enrichment	AKT3	2.33
94	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.33
95	Rare venous malformation	Enrichment	PIK3CA	2.33
96	Diaphragmatic eventration	Enrichment	PIK3CA	2.33
97	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.33
98	Menke-hennekam syndrome	Enrichment	CREBBP	2.33
99	Rare combined vascular malformation	Enrichment	PIK3CA	2.33
100	Cavernous lymphangioma	Enrichment	PIK3CA	2.33
101	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.33
102	Autosomal dominant mendelian susceptibility to mycobacterial diseases due to partial ifngammar2 deficiency	Enrichment	IFNGR2	2.33
103	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.33
104	Mendelian susceptibility to mycobacterial diseases due to partial jak1 deficiency	Enrichment	JAK1	2.33
105	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.33
106	Macrodactyly of toe	Enrichment	PIK3CA	2.33
107	Primary peritoneal carcinoma	Enrichment	BRCA1	2.33
108	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.33
109	Malignant astrocytoma	Enrichment	PTPN11	2.33
110	Scoliosis	Enrichment	CREBBP, PTPN11	2.26
111	Prostate cancer	Enrichment	BRCA1, PIK3CA	2.10
112	Long qt syndrome	Enrichment	CALM1, CALM2	2.04
113	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.03
114	Burkitt lymphoma	Enrichment	MYC	2.03
115	Thumb deformity	Enrichment	CREBBP	2.03
116	Ovarian germ cell cancer	Enrichment	CBL	2.03
117	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.03
118	Keratosis, seborrheic	Enrichment	PIK3CA	2.03
119	Roifman-chitayat syndrome	Enrichment	PIK3CD	2.03
120	Noonan syndrome 8	Enrichment	PIK3CA	2.03
121	Thrombocythemia 3	Enrichment	JAK2	2.03
122	Long qt syndrome 14	Enrichment	CALM1	2.03
123	Immunodeficiency 31c	Enrichment	STAT1	2.03
124	Fanconi anemia, complementation group s	Enrichment	BRCA1	2.03
125	Werner syndrome	Enrichment	PTPN11	2.03
126	Menke-hennekam syndrome 2	Enrichment	EP300	2.03
127	Pancreatic cancer 4	Enrichment	BRCA1	2.03
128	Acute myeloid leukemia with kat6a-crebbp fusion	Enrichment	CREBBP	2.03
129	Senior-loken syndrome 7	Enrichment	AKT3	2.03
130	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	2.03
131	Autoinflammation, immune dysregulation, and eosinophilia	Enrichment	JAK1	2.03
132	Immune system disease	Enrichment	PIK3CD	2.03
133	Bardet-biedl syndrome 16	Enrichment	AKT3	2.03
134	Inflammatory breast carcinoma	Enrichment	BRCA1	2.03
135	Polycythemia	Enrichment	JAK2	2.03
136	Peritoneum cancer	Enrichment	BRCA1	2.03
137	Bilateral breast cancer	Enrichment	BRCA1	2.03
138	Hypereosinophilic syndrome	Enrichment	JAK2	2.03
139	Immunodeficiency 117	Enrichment	IRF1	2.03
140	Malignant germ cell tumor of ovary	Enrichment	CBL	2.03
141	Fanconi anemia, complementation group a	Enrichment	BRCA1, FANCC	1.94
142	Immune thrombocytopenia	Enrichment	SOCS1	1.86
143	Gillespie syndrome	Enrichment	ITPR1	1.86
144	Polycythemia vera	Enrichment	JAK2	1.86
145	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.86
146	Tuberous sclerosis 1	Enrichment	IFNG	1.86
147	Langerhans cell histiocytosis	Enrichment	MAP2K1	1.86
148	Hepatitis c virus	Enrichment	IFNG	1.86
149	Tuberous sclerosis 2	Enrichment	IFNG	1.86
150	Immunodeficiency 28	Enrichment	IFNGR2	1.86
151	Autoinflammatory syndrome, familial, with or without immunodeficiency	Enrichment	SOCS1	1.86
152	Tethered spinal cord syndrome	Enrichment	CREBBP	1.86
153	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.86
154	Torsion dystonia 1	Enrichment	EIF2AK2	1.86
155	Intraocular pressure quantitative trait locus	Enrichment	CREBBP	1.86
156	Immunodeficiency 44	Enrichment	STAT2	1.86
157	Tricuspid valve insufficiency	Enrichment	PTPN11	1.86
158	Keratoacanthoma	Enrichment	PIK3CA	1.86
159	Erythrocytosis, familial, 1	Enrichment	JAK2	1.73
160	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1	1.73
161	Anemia, autoimmune hemolytic	Enrichment	SOCS1	1.73
162	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.73
163	Budd-chiari syndrome	Enrichment	JAK2	1.73
164	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.73
165	Cholangiocarcinoma	Enrichment	BRCA1	1.73
166	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1	1.73
167	Hepatitis b	Enrichment	IFNGR1	1.73
168	Cerebrovascular disease	Enrichment	PIK3CA	1.73
169	Noonan syndrome with multiple lentigines	Enrichment	PTPN11	1.73
170	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.73
171	Cerebral malaria	Enrichment	ICAM1	1.73
172	Thrombocytopenia	Enrichment	PTPN11, SRC	1.68
173	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2A, CAMK2B	1.65
174	Capillary malformations, congenital	Enrichment	PIK3CA	1.64
175	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.64
176	Rubinstein-taybi syndrome 2	Enrichment	EP300	1.64
177	Lymphoma	Enrichment	PTPN11	1.64
178	Aggressive systemic mastocytosis	Enrichment	CBL	1.64
179	Idiopathic aplastic anemia	Enrichment	IFNG	1.64
180	Inherited cancer-predisposing syndrome	Enrichment	BRCA1, FANCC, PTPN11	1.63
181	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.56
182	Cowden syndrome 1	Enrichment	PIK3CA	1.56
183	Hemihyperplasia, isolated	Enrichment	PIK3CA	1.56
184	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.56
185	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.56
186	Patent ductus arteriosus	Enrichment	PTPN11	1.56
187	Chronic mucocutaneous candidiasis	Enrichment	STAT1	1.56
188	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.56
189	Hypertrichosis	Enrichment	CREBBP	1.56
190	Myeloma, multiple	Enrichment	CREBBP, PIK3R2	1.56
191	Nevus, epidermal	Enrichment	PIK3CA	1.49
192	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A	1.49
193	Noonan syndrome 3	Enrichment	PTPN11	1.49
194	Essential thrombocythemia	Enrichment	JAK2	1.49
195	Gallbladder cancer	Enrichment	PIK3CA	1.49
196	Megacolon	Enrichment	AKT3	1.49
197	Overgrowth syndrome	Enrichment	PIK3R1	1.49
198	Fanconi anemia, complementation group c	Enrichment	FANCC	1.44
199	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.44
200	Charge syndrome	Enrichment	EP300	1.39
201	Leukemia, acute lymphoblastic 3	Enrichment	JAK2	1.39
202	Adult hepatocellular carcinoma	Enrichment	PIK3CA	1.39
203	Autism	Enrichment	CAMK2G, CREBBP	1.36
204	Aplastic anemia	Enrichment	IFNG	1.34
205	Polymicrogyria	Enrichment	AKT3	1.34
206	Pectus excavatum	Enrichment	PTPN11	1.30
207	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.30
208	Uterine corpus cancer	Enrichment	BRCA1	1.30
209	Epicanthus	Enrichment	PTPN11	1.26
210	Lip and oral cavity carcinoma	Enrichment	PIK3CA	1.26
211	Breast-ovarian cancer, familial 1	Enrichment	BRCA1	1.23
212	Nk-cell enteropathy	Enrichment	PIK3CB	1.23
213	Multiple sclerosis	Enrichment	ITPR1	1.20
214	Osteoporosis	Enrichment	SRC	1.20
215	Periventricular nodular heterotopia	Enrichment	BRCA1	1.20
216	Heart disease	Enrichment	CREBBP	1.20
217	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1	1.20
218	Polydactyly, postaxial, type a1	Enrichment	EP300	1.17
219	Corpus callosum, agenesis of	Enrichment	CREBBP	1.17
220	Anterior segment dysgenesis	Enrichment	ITPR1	1.17
221	Lynch syndrome	Enrichment	PIK3CA	1.17
222	Isolated corpus callosum agenesis	Enrichment	CREBBP	1.17
223	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	CREBBP	1.17
224	Sudden infant death syndrome	Enrichment	CALM2	1.12
225	Heart, malformation of	Enrichment	MAPK1	1.09
226	Human immunodeficiency virus type 1	Enrichment	IFNG	1.09
227	Patent foramen ovale	Enrichment	PTPN11	1.09
228	Behcet syndrome	Enrichment	IFNGR1	1.07
229	Congenital nervous system abnormality	Enrichment	CAMK2B, CREBBP	1.06
230	Nervous system disease	Enrichment	CAMK2B, CREBBP	1.06
231	Autism spectrum disorder	Enrichment	MAP2K1, PTPN11	1.04
232	Hepatocellular carcinoma	Enrichment	PIK3CA	1.01
233	Malaria	Enrichment	ICAM1	0.99
234	Precursor t-cell acute lymphoblastic leukemia	Enrichment	MYC	0.99
235	Pancreatic cancer	Enrichment	BRCA1	0.96
236	Hydrops fetalis, nonimmune	Enrichment	PTPN11	0.94
237	Strabismus	Enrichment	PTPN11	0.93
238	Non-immune hydrops fetalis	Enrichment	PTPN11	0.87
239	Dystonia	Enrichment	CAMK2B	0.82
240	Systemic lupus erythematosus	Enrichment	SOCS1	0.78
241	Leukemia, acute myeloid	Enrichment	JAK2	0.77
242	Type 2 diabetes mellitus	Enrichment	AKT2	0.75
243	Hypertrophic cardiomyopathy	Enrichment	PTPN11	0.74
244	Hypertelorism	Enrichment	PIK3CA	0.67
245	Spastic ataxia	Enrichment	ITPR1	0.66
246	Hereditary breast ovarian cancer syndrome	Enrichment	BRCA1	0.65
247	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	PTPN11	0.64
248	Primary ovarian insufficiency	Enrichment	JAK2	0.62

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Immune response_IFN gamma signaling pathway

Pathway Network for Immune response_IFN gamma signaling pathway

Member Pathways for Immune response_IFN gamma signaling pathway

Pathways in the Immune response_IFN gamma signaling pathway SuperPath

Associated Genes for Immune response_IFN gamma signaling pathway

Associated Disorders for Immune response_IFN gamma signaling pathway

Disorders associated with Immune response_IFN gamma signaling pathway SuperPath

STRING Interaction Network for Immune response_IFN gamma signaling pathway

Sources for Immune response_IFN gamma signaling pathway