Immune response NFAT in immune response
Pathway network for the Immune response NFAT in immune response SuperPath
Sources:
- GeneGo (Thomson Reuters)
Pathways in the Immune response NFAT in immune response SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Immune response NFAT in immune response | GeneGo (Thomson Reuters) | |
| 2 | Immune response ICOS pathway in T-helper cell | GeneGo (Thomson Reuters) | |
| 3 | Immune response T cell receptor signaling pathway | GeneGo (Thomson Reuters) | |
| 4 | Immune response CD28 signaling | GeneGo (Thomson Reuters) |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | CALM1 | Calmodulin 1 | Protein Coding | 4 |
| 2 | CALM2 | Calmodulin 2 | Protein Coding | 4 |
| 3 | CALM3 | Calmodulin 3 | Protein Coding | 4 |
| 4 | CD3D | CD3 Delta Subunit Of T-Cell Receptor Complex | Protein Coding | 4 |
| 5 | CD3E | CD3 Epsilon Subunit Of T-Cell Receptor Complex | Protein Coding | 4 |
| 6 | CD3G | CD3 Gamma Subunit Of T-Cell Receptor Complex | Protein Coding | 4 |
| 7 | CD247 | CD247 Molecule | Protein Coding | 4 |
| 8 | IKBKB | Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta | Protein Coding | 4 |
| 9 | ITK | IL2 Inducible T Cell Kinase | Protein Coding | 4 |
| 10 | ITPR1 | Inositol 1,4,5-Trisphosphate Receptor Type 1 | Protein Coding | 4 |
| 11 | ITPR2 | Inositol 1,4,5-Trisphosphate Receptor Type 2 | Protein Coding | 4 |
| 12 | ITPR3 | Inositol 1,4,5-Trisphosphate Receptor Type 3 | Protein Coding | 4 |
| 13 | LCK | LCK Proto-Oncogene, Src Family Tyrosine Kinase | Protein Coding | 4 |
| 14 | LCP2 | Lymphocyte Cytosolic Protein 2 | Protein Coding | 4 |
| 15 | NFATC2 | Nuclear Factor Of Activated T Cells 2 | Protein Coding | 4 |
| 16 | NFKB1 | Nuclear Factor Kappa B Subunit 1 | Protein Coding | 4 |
| 17 | NFKB2 | Nuclear Factor Kappa B Subunit 2 | Protein Coding | 4 |
| 18 | NFKBIA | NFKB Inhibitor Alpha | Protein Coding | 4 |
| 19 | NFKBIB | NFKB Inhibitor Beta | Protein Coding | 4 |
| 20 | NFKBIE | NFKB Inhibitor Epsilon | Protein Coding | 4 |
| 21 | PLCG1 | Phospholipase C Gamma 1 | Protein Coding | 4 |
| 22 | PPP3CA | Protein Phosphatase 3 Catalytic Subunit Alpha | Protein Coding | 4 |
| 23 | PPP3CB | Protein Phosphatase 3 Catalytic Subunit Beta | Protein Coding | 4 |
| 24 | PPP3CC | Protein Phosphatase 3 Catalytic Subunit Gamma | Protein Coding | 4 |
| 25 | PRKCQ | Protein Kinase C Theta | Protein Coding | 4 |
| 26 | RAC1 | Rac Family Small GTPase 1 | Protein Coding | 4 |
| 27 | REL | REL Proto-Oncogene, NF-KB Subunit | Protein Coding | 4 |
| 28 | RELA | RELA Proto-Oncogene, NF-KB Subunit | Protein Coding | 4 |
| 29 | RELB | RELB Proto-Oncogene, NF-KB Subunit | Protein Coding | 4 |
| 30 | TRA | T Cell Receptor Alpha Locus | Protein Coding | 4 |
| 31 | TRB | T Cell Receptor Beta Locus | Protein Coding | 4 |
| 32 | VAV1 | Vav Guanine Nucleotide Exchange Factor 1 | Protein Coding | 4 |
| 33 | ZAP70 | Zeta Chain Of T Cell Receptor Associated Protein Kinase 70 | Protein Coding | 4 |
| 34 | LAT | Linker For Activation Of T Cells | Protein Coding | 4 |
| 35 | TRBV17 | T Cell Receptor Beta Variable 17 (Non-Functional) | Protein Coding | 4 |
| 36 | TRBV11-3 | T Cell Receptor Beta Variable 11-3 | Protein Coding | 4 |
| 37 | TRBV11-2 | T Cell Receptor Beta Variable 11-2 | Protein Coding | 4 |
| 38 | TRBV11-1 | T Cell Receptor Beta Variable 11-1 | Protein Coding | 4 |
| 39 | TRAV24 | T Cell Receptor Alpha Variable 24 | Protein Coding | 4 |
| 40 | TRAJ18 | T Cell Receptor Alpha Joining 18 | Protein Coding | 4 |
| 41 | TRAC | T Cell Receptor Alpha Constant | Protein Coding | 4 |
| 42 | AKT1 | AKT Serine/Threonine Kinase 1 | Protein Coding | 3 |
| 43 | AKT2 | AKT Serine/Threonine Kinase 2 | Protein Coding | 3 |
| 44 | CD28 | CD28 Molecule | Protein Coding | 3 |
| 45 | CD80 | CD80 Molecule | Protein Coding | 3 |
| 46 | CD86 | CD86 Molecule | Protein Coding | 3 |
| 47 | CHUK | Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex | Protein Coding | 3 |
| 48 | HLA-DMA | Major Histocompatibility Complex, Class II, DM Alpha | Protein Coding | 3 |
| 49 | HLA-DMB | Major Histocompatibility Complex, Class II, DM Beta | Protein Coding | 3 |
| 50 | HLA-DOA | Major Histocompatibility Complex, Class II, DO Alpha | Protein Coding | 3 |
| 51 | HLA-DOB | Major Histocompatibility Complex, Class II, DO Beta | Protein Coding | 3 |
| 52 | HLA-DPA1 | Major Histocompatibility Complex, Class II, DP Alpha 1 | Protein Coding | 3 |
| 53 | HLA-DPB1 | Major Histocompatibility Complex, Class II, DP Beta 1 | Protein Coding | 3 |
| 54 | HLA-DPB2 | Major Histocompatibility Complex, Class II, DP Beta 2 (Pseudogene) | Pseudogene | 3 |
| 55 | HLA-DQA1 | Major Histocompatibility Complex, Class II, DQ Alpha 1 | Protein Coding | 3 |
| 56 | HLA-DQA2 | Major Histocompatibility Complex, Class II, DQ Alpha 2 | Protein Coding | 3 |
| 57 | HLA-DQB1 | Major Histocompatibility Complex, Class II, DQ Beta 1 | Protein Coding | 3 |
| 58 | HLA-DQB2 | Major Histocompatibility Complex, Class II, DQ Beta 2 | Protein Coding | 3 |
| 59 | HLA-DQB3 | Major Histocompatibility Complex, Class II, DQ Beta 3 | Protein Coding | 3 |
| 60 | HLA-DRA | Major Histocompatibility Complex, Class II, DR Alpha | Protein Coding | 3 |
| 61 | HLA-DRB1 | Major Histocompatibility Complex, Class II, DR Beta 1 | Protein Coding | 3 |
| 62 | HLA-DRB3 | Major Histocompatibility Complex, Class II, DR Beta 3 | Protein Coding | 3 |
| 63 | HLA-DRB4 | Major Histocompatibility Complex, Class II, DR Beta 4 | Protein Coding | 3 |
| 64 | HLA-DRB5 | Major Histocompatibility Complex, Class II, DR Beta 5 | Protein Coding | 3 |
| 65 | NFATC1 | Nuclear Factor Of Activated T Cells 1 | Protein Coding | 3 |
| 66 | NFATC3 | Nuclear Factor Of Activated T Cells 3 | Protein Coding | 3 |
| 67 | NFATC4 | Nuclear Factor Of Activated T Cells 4 | Protein Coding | 3 |
| 68 | PIK3CA | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha | Protein Coding | 3 |
| 69 | PIK3CB | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta | Protein Coding | 3 |
| 70 | PIK3CD | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta | Protein Coding | 3 |
| 71 | PIK3R1 | Phosphoinositide-3-Kinase Regulatory Subunit 1 | Protein Coding | 3 |
| 72 | PIK3R2 | Phosphoinositide-3-Kinase Regulatory Subunit 2 | Protein Coding | 3 |
| 73 | PIK3R3 | Phosphoinositide-3-Kinase Regulatory Subunit 3 | Protein Coding | 3 |
| 74 | IKBKG | Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma | Protein Coding | 3 |
| 75 | AKT3 | AKT Serine/Threonine Kinase 3 | Protein Coding | 3 |
| 76 | TRAT1 | T Cell Receptor Associated Transmembrane Adaptor 1 | Protein Coding | 3 |
| 77 | GRB2 | Growth Factor Receptor Bound Protein 2 | Protein Coding | 3 |
| 78 | GSK3B | Glycogen Synthase Kinase 3 Beta | Protein Coding | 2 |
| 79 | NFAT5 | Nuclear Factor Of Activated T Cells 5 | Protein Coding | 2 |
| 80 | BAD | BCL2 Associated Agonist Of Cell Death | Protein Coding | 2 |
| 81 | FYN | FYN Proto-Oncogene, Src Family Tyrosine Kinase | Protein Coding | 2 |
| 82 | BTK | Bruton Tyrosine Kinase | Protein Coding | 1 |
| 83 | CD79A | CD79a Molecule | Protein Coding | 1 |
| 84 | CD79B | CD79b Molecule | Protein Coding | 1 |
| 85 | FCER1A | Fc Epsilon Receptor Ia | Protein Coding | 1 |
| 86 | MS4A2 | Membrane Spanning 4-Domains A2 | Protein Coding | 1 |
| 87 | FCER1G | Fc Epsilon Receptor Ig | Protein Coding | 1 |
| 88 | GSK3A | Glycogen Synthase Kinase 3 Alpha | Protein Coding | 1 |
| 89 | IGH | Immunoglobulin Heavy Locus | Protein Coding | 1 |
| 90 | IGHE | Immunoglobulin Heavy Constant Epsilon | Protein Coding | 1 |
| 91 | IGHM | Immunoglobulin Heavy Constant Mu | Protein Coding | 1 |
| 92 | IGKC | Immunoglobulin Kappa Constant | Protein Coding | 1 |
| 93 | IGKV@ | Immunoglobulin Kappa Variable Cluster | Gene Cluster | 1 |
| 94 | IGL | Immunoglobulin Lambda Locus | Protein Coding | 1 |
| 95 | IGLV@ | Immunoglobulin Lambda Variable Cluster | Gene Cluster | 1 |
| 96 | LYN | LYN Proto-Oncogene, Src Family Tyrosine Kinase | Protein Coding | 1 |
| 97 | PLCG2 | Phospholipase C Gamma 2 | Protein Coding | 1 |
| 98 | SYK | Spleen Associated Tyrosine Kinase | Protein Coding | 1 |
| 99 | IGKJ | Immunoglobulin Kappa Joining Cluster | Genetic Locus | 1 |
| 100 | IGLJ | Immunoglobulin Lambda Joining Cluster | Genetic Locus | 1 |
| 101 | IGHV3-23 | Immunoglobulin Heavy Variable 3-23 | Protein Coding | 1 |
| 102 | BLNK | B Cell Linker | Protein Coding | 1 |
| 103 | IGK | Immunoglobulin Kappa Locus | Protein Coding | 1 |
| 104 | CDC42 | Cell Division Cycle 42 | Protein Coding | 1 |
| 105 | GNA15 | G Protein Subunit Alpha 15 | Protein Coding | 1 |
| 106 | GNB1 | G Protein Subunit Beta 1 | Protein Coding | 1 |
| 107 | GNB2 | G Protein Subunit Beta 2 | Protein Coding | 1 |
| 108 | GNB3 | G Protein Subunit Beta 3 | Protein Coding | 1 |
| 109 | GNG3 | G Protein Subunit Gamma 3 | Protein Coding | 1 |
| 110 | GNG4 | G Protein Subunit Gamma 4 | Protein Coding | 1 |
| 111 | GNG5 | G Protein Subunit Gamma 5 | Protein Coding | 1 |
| 112 | GNG7 | G Protein Subunit Gamma 7 | Protein Coding | 1 |
| 113 | GNG10 | G Protein Subunit Gamma 10 | Protein Coding | 1 |
| 114 | GNG11 | G Protein Subunit Gamma 11 | Protein Coding | 1 |
| 115 | GNGT1 | G Protein Subunit Gamma Transducin 1 | Protein Coding | 1 |
| 116 | GNGT2 | G Protein Subunit Gamma Transducin 2 | Protein Coding | 1 |
| 117 | PDPK1 | 3-Phosphoinositide Dependent Protein Kinase 1 | Protein Coding | 1 |
| 118 | PIK3CG | Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma | Protein Coding | 1 |
| 119 | GAB2 | GRB2 Associated Binding Protein 2 | Protein Coding | 1 |
| 120 | GNB5 | G Protein Subunit Beta 5 | Protein Coding | 1 |
| 121 | ICOSLG | Inducible T Cell Costimulator Ligand | Protein Coding | 1 |
| 122 | PIK3R5 | Phosphoinositide-3-Kinase Regulatory Subunit 5 | Protein Coding | 1 |
| 123 | ICOS | Inducible T Cell Costimulator | Protein Coding | 1 |
| 124 | GNG13 | G Protein Subunit Gamma 13 | Protein Coding | 1 |
| 125 | GNG2 | G Protein Subunit Gamma 2 | Protein Coding | 1 |
| 126 | GNG12 | G Protein Subunit Gamma 12 | Protein Coding | 1 |
| 127 | GNB4 | G Protein Subunit Beta 4 | Protein Coding | 1 |
| 128 | GNG8 | G Protein Subunit Gamma 8 | Protein Coding | 1 |
| 129 | CD4 | CD4 Molecule | Protein Coding | 1 |
| 130 | ELK1 | ETS Transcription Factor ELK1 | Protein Coding | 1 |
| 131 | FOS | Fos Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 132 | HRAS | HRas Proto-Oncogene, GTPase | Protein Coding | 1 |
| 133 | MAPK1 | Mitogen-Activated Protein Kinase 1 | Protein Coding | 1 |
| 134 | MAPK3 | Mitogen-Activated Protein Kinase 3 | Protein Coding | 1 |
| 135 | MAP2K1 | Mitogen-Activated Protein Kinase Kinase 1 | Protein Coding | 1 |
| 136 | MAP2K2 | Mitogen-Activated Protein Kinase Kinase 2 | Protein Coding | 1 |
| 137 | PTPRC | Protein Tyrosine Phosphatase Receptor Type C | Protein Coding | 1 |
| 138 | RAF1 | Raf-1 Proto-Oncogene, Serine/Threonine Kinase | Protein Coding | 1 |
| 139 | SOS1 | SOS Ras/Rac Guanine Nucleotide Exchange Factor 1 | Protein Coding | 1 |
| 140 | SOS2 | SOS Ras/Rho Guanine Nucleotide Exchange Factor 2 | Protein Coding | 1 |
| 141 | UBA52 | Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1 | Protein Coding | 1 |
| 142 | UBB | Ubiquitin B | Protein Coding | 1 |
| 143 | UBC | Ubiquitin C | Protein Coding | 1 |
| 144 | UBE2N | Ubiquitin Conjugating Enzyme E2 N | Protein Coding | 1 |
| 145 | UBE2V2 | Ubiquitin Conjugating Enzyme E2 V2 | Protein Coding | 1 |
| 146 | BCL10 | BCL10 Immune Signaling Adaptor | Protein Coding | 1 |
| 147 | RASGRP1 | RAS Guanyl Releasing Protein 1 | Protein Coding | 1 |
| 148 | MALT1 | MALT1 Paracaspase | Protein Coding | 1 |
| 149 | CARD11 | Caspase Recruitment Domain Family Member 11 | Protein Coding | 1 |
| 150 | BCL2L1 | BCL2 Like 1 | Protein Coding | 1 |
| 151 | JUN | Jun Proto-Oncogene, AP-1 Transcription Factor Subunit | Protein Coding | 1 |
| 152 | MAP3K1 | Mitogen-Activated Protein Kinase Kinase Kinase 1 | Protein Coding | 1 |
| 153 | PAK1 | P21 (RAC1) Activated Kinase 1 | Protein Coding | 1 |
| 154 | MAPK8 | Mitogen-Activated Protein Kinase 8 | Protein Coding | 1 |
| 155 | MAPK9 | Mitogen-Activated Protein Kinase 9 | Protein Coding | 1 |
| 156 | MAPK10 | Mitogen-Activated Protein Kinase 10 | Protein Coding | 1 |
| 157 | MAP2K7 | Mitogen-Activated Protein Kinase Kinase 7 | Protein Coding | 1 |
| 158 | MAP2K4 | Mitogen-Activated Protein Kinase Kinase 4 | Protein Coding | 1 |
| 159 | PIP5K1A | Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Alpha | Protein Coding | 1 |
| 160 | PIP5K1B | Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Beta | Protein Coding | 1 |
| 161 | GRAP2 | GRB2 Related Adaptor Protein 2 | Protein Coding | 1 |
| 162 | PIP5K1C | Phosphatidylinositol-4-Phosphate 5-Kinase Type 1 Gamma | Protein Coding | 1 |
Disorders associated with Immune response NFAT in immune response SuperPath
according to GeneCards Suite gene sharing