Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

No Pathway Network information available for Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1T-b+ severe combined immunodeficiency due to cd3delta/cd3epsilon/cd3zetaEnrichmentCD247, CD3D, CD3E6.07
2Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1EnrichmentTREM2, TYROBP4.04
3Severe cutaneous adverse reactionEnrichmentHLA-A, HLA-B4.04
4Ehlers-danlos syndrome, arthrochalasia type, 2EnrichmentCOL1A1, COL1A24.04
5Ehlers-danlos/osteogenesis imperfecta syndromeEnrichmentCOL1A1, COL1A24.04
6Common variable immunodeficiency phenotype due to cd19/cd81 deficiencyEnrichmentCD19, CD814.04
7Severe combined immunodeficiencyEnrichmentCD247, CD3D, CD3E, CD3G3.58
8High bone mass osteogenesis imperfectaEnrichmentCOL1A1, COL1A23.57
9Ehlers-danlos syndrome, arthrochalasia type, 1EnrichmentCOL1A1, COL1A23.27
10Osteogenesis imperfecta with normal sclerae, dominant formEnrichmentCOL1A1, COL1A23.27
11Ehlers-danlos syndromeEnrichmentCOL1A1, COL1A2, COL3A13.13
12Ehlers-danlos syndrome, classic type, 1EnrichmentCOL1A1, COL1A22.88
13Osteogenesis imperfecta, type iEnrichmentCOL1A1, COL1A22.88
14Classic ehlers-danlos syndromeEnrichmentCOL1A1, COL1A22.88
15Osteogenesis imperfecta, type iiEnrichmentCOL1A1, COL1A22.73
16Primary bone dysplasiaEnrichmentCOL1A1, COL1A22.41
17OsteochondrodysplasiaEnrichmentCOL1A1, COL1A22.32
18Osteogenesis imperfecta, type ivEnrichmentCOL1A1, COL1A22.18
19OsteoporosisEnrichmentCOL1A1, COL1A22.11
20Osteogenesis imperfecta, type iiiEnrichmentCOL1A1, COL1A22.05
21Stickler syndrome, type iEnrichmentCOL2A12.02
22Blood group system, landsteiner-wienerEnrichmentICAM42.02
23Spondyloarthropathy 1EnrichmentHLA-B2.02
24Epiphyseal dysplasia, multiple, with myopia and conductive deafnessEnrichmentCOL2A12.02
25Ehlers-danlos syndrome, cardiac valvular typeEnrichmentCOL1A22.02
26Spondylometaphyseal dysplasia, algerian typeEnrichmentCOL2A12.02
27C syndromeEnrichmentCD962.02
28Osteoarthritis with mild chondrodysplasiaEnrichmentCOL2A12.02
29Avascular necrosis of femoral head, primary, 1EnrichmentCOL2A12.02
30Czech dysplasiaEnrichmentCOL2A12.02
31Psoriasis 1EnrichmentHLA-C2.02
32Kniest dysplasiaEnrichmentCOL2A12.02
33Hemolytic uremic syndrome, atypical 5EnrichmentC32.02
34Platyspondylic lethal skeletal dysplasia, torrance typeEnrichmentCOL2A12.02
35Spondyloepiphyseal dysplasia, stanescu typeEnrichmentCOL2A12.02
36Immunodeficiency 116EnrichmentCD8A2.02
37Immunodeficiency, common variable, 6EnrichmentCD812.02
38Immunodeficiency 43EnrichmentB2M2.02
39Immunodeficiency 20EnrichmentFCGR3A2.02
40Acrogeria, gottron typeEnrichmentCOL3A12.02
41Achondrogenesis, type iiEnrichmentCOL2A12.02
42Immunodeficiency with hyper-igm, type 1EnrichmentCD40LG2.02
43Lymphoproliferative syndrome, x-linked, 1EnrichmentSH2D1A2.02
44Combined osteogenesis imperfecta and ehlers-danlos syndrome 2EnrichmentCOL1A22.02
45Spondyloperipheral dysplasiaEnrichmentCOL2A12.02
46Immunodeficiency 18EnrichmentCD3E2.02
47Dialysis-related amyloidosisEnrichmentB2M2.02
48Ankylosing spondylitis 1EnrichmentHLA-B2.02
49Immunodeficiency 25EnrichmentCD2472.02
50Immunodeficiency with hyper-igm, type 3EnrichmentCD402.02
51Birdshot chorioretinopathyEnrichmentHLA-A2.02
52Malaria, mildEnrichmentNCR32.02
53Stickler syndrome, type i, nonsyndromic ocularEnrichmentCOL2A12.02
54Alzheimer disease 17EnrichmentTREM22.02
55Immunodeficiency, common variable, 3EnrichmentCD192.02
56Macular degeneration, age-related, 9EnrichmentC32.02
57Complement component 3 deficiency, autosomal recessiveEnrichmentC32.02
58Reactive arthritisEnrichmentHLA-B2.02
59Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2EnrichmentTREM22.02
60Vitreoretinopathy with phalangeal epiphyseal dysplasiaEnrichmentCOL2A12.02
61Asphyxia neonatorumEnrichmentCOL1A12.02
62Amyloidosis, hereditary systemic 6EnrichmentB2M2.02
63Immunodeficiency 19, severe combinedEnrichmentCD3D2.02
64Complement component 3 deficiencyEnrichmentC32.02
65Late-onset junctional epidermolysis bullosaEnrichmentCOL17A12.02
66Autosomal dominant rhegmatogenous retinal detachmentEnrichmentCOL2A12.02
67Membranoproliferative glomerulonephritisEnrichmentC32.02
68Primary membranoproliferative glomerulonephritisEnrichmentC32.02
69Multiple epiphyseal dysplasia with myopia and deafnessEnrichmentCOL2A12.02
70Cd40 ligand deficiencyEnrichmentCD40LG2.02
71HypochondrogenesisEnrichmentCOL2A12.02
72Pulmonary arterial hypertension associated with connective tissue diseaseEnrichmentHLA-B2.02
73Immunodeficiency 19EnrichmentCD3D2.02
74DysspondyloenchondromatosisEnrichmentCOL2A12.02
75Abdominal aortic aneurysmEnrichmentCOL3A12.02
76Type 2 collagen-related bone disorderEnrichmentCOL2A12.02
77Ehlers-danlos syndrome, vascular typeEnrichmentCOL3A11.72
78Epiphyseal dysplasia, multiple, 1EnrichmentCOL1A11.72
79Amelogenesis imperfecta, type ibEnrichmentCOL17A11.72
80Amelogenesis imperfecta, type iaEnrichmentCOL17A11.72
81Leukocyte adhesion deficiency, type iEnrichmentITGB21.72
82Ehlers-danlos syndrome, hypermobility typeEnrichmentCOL3A11.72
83Spondyloepimetaphyseal dysplasia, strudwick typeEnrichmentCOL2A11.72
84Spondylometaphyseal dysplasia, corner fracture typeEnrichmentCOL2A11.72
85Bruck syndrome 1EnrichmentCOL1A21.72
86Otospondylomegaepiphyseal dysplasia, autosomal recessiveEnrichmentCOL2A11.72
87Dermatofibrosarcoma protuberansEnrichmentCOL1A11.72
88Legg-calve-perthes diseaseEnrichmentCOL2A11.72
89Leukocyte adhesion deficiency, type iiiEnrichmentITGB21.72
90Epithelial recurrent erosion dystrophyEnrichmentCOL17A11.72
91Otospondylomegaepiphyseal dysplasia, autosomal dominantEnrichmentCOL2A11.72
92Combined osteogenesis imperfecta and ehlers-danlos syndrome 1EnrichmentCOL1A11.72
93Epidermolysis bullosa, junctional 4, intermediateEnrichmentCOL17A11.72
94Polymicrogyria with or without vascular-type ehlers-danlos syndromeEnrichmentCOL3A11.72
95Stevens-johnson syndromeEnrichmentHLA-B1.72
96Aortic dissectionEnrichmentCOL3A11.72
97Lymphoproliferative syndromeEnrichmentSH2D1A1.72
98Stickler syndrome, type iiEnrichmentCOL1A11.72
99Familial avascular necrosis of the femoral headEnrichmentCOL2A11.72
100Immunodeficiency 17EnrichmentCD3G1.72
101Localized junctional epidermolysis bullosa, non-herlitz typeEnrichmentCOL17A11.72
102Dentinogenesis imperfectaEnrichmentCOL1A21.72
103Brittle bone disorderEnrichmentCOL1A1, COL1A21.69
104MalariaEnrichmentFCGR2B, ICAM11.69
105Mccune-albright syndromeEnrichmentCOL2A11.55
106Spondyloepiphyseal dysplasia congenitaEnrichmentCOL2A11.55
107Takayasu arteritisEnrichmentHLA-B1.55
108Caffey diseaseEnrichmentCOL1A11.55
109Genetic atypical hemolytic-uremic syndromeEnrichmentC31.55
110Multiple epiphyseal dysplasiaEnrichmentCOL2A11.55
111PhenylketonuriaEnrichmentCOL1A11.42
112Temporal arteritisEnrichmentHLA-B1.42
113Retinitis pigmentosa 26EnrichmentITGA41.42
114Corneal dystrophyEnrichmentCOL17A11.42
115Cerebral malariaEnrichmentICAM11.42
116Immunodeficiency by defective expression of mhc class iEnrichmentB2M1.42
117Amyloidosis, hereditary systemic 2EnrichmentB2M1.33
118Retinal detachmentEnrichmentCOL2A11.33
119Hydatidiform mole, recurrent, 1EnrichmentNCR11.33
120Familial cerebral saccular aneurysmEnrichmentCOL3A11.33
121Developmental dysplasia of the hip 1EnrichmentCOL2A11.25
122Epidermolysis bullosa, junctional 1a, intermediateEnrichmentCOL17A11.25
123Junctional epidermolysis bullosa non-herlitz typeEnrichmentCOL17A11.25
124KeratoconusEnrichmentCOL1A11.25
125Atypical hemolytic uremic syndrome with complement gene abnormalityEnrichmentC31.25
126Multiple enchondromatosis, maffucci typeEnrichmentCOL2A11.19
127Semantic dementiaEnrichmentTREM21.19
128Common variable immunodeficiencyEnrichmentCD40LG1.19
129Oligoarticular juvenile idiopathic arthritisEnrichmentCD2471.19
130Early-onset autosomal dominant alzheimer diseaseEnrichmentTREM21.19
131Rheumatoid factor-negative juvenile idiopathic arthritisEnrichmentCD2471.19
132B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)EnrichmentHLA-C1.19
133Familial thoracic aortic aneurysm and aortic dissectionEnrichmentCOL1A1, COL3A11.18
134Spastic paraplegia 4, autosomal dominantEnrichmentCOL3A11.13
135Lymphoma, non-hodgkin, familialEnrichmentB2M1.13
136Progressive non-fluent aphasiaEnrichmentTREM21.08
137Junctional epidermolysis bullosaEnrichmentCOL17A11.08
138Familial thoracic aortic aneurysm and dissectionEnrichmentCOL3A11.08
139Behavioral variant of frontotemporal dementiaEnrichmentTREM21.08
140Marfan syndromeEnrichmentCOL2A11.04
141Amelogenesis imperfecta, type ieEnrichmentCOL17A11.04
142Stickler syndromeEnrichmentCOL2A11.04
143AsthmaEnrichmentHLA-G1.00
144Frontotemporal dementia 1EnrichmentTREM21.00
145Neural tube defectsEnrichmentITGB10.93
146Amelogenesis imperfectaEnrichmentCOL17A10.93
147Aortic aneurysm, familial thoracic 1EnrichmentCOL3A10.90
148Isolated macular dystrophyEnrichmentITGA40.90
149MyopiaEnrichmentCOL2A10.87
150Atypical hemolytic-uremic syndromeEnrichmentC30.87
151Heart, malformation ofEnrichmentCOL2A10.80
152Human immunodeficiency virus type 1EnrichmentHLA-C0.80
153Behcet syndromeEnrichmentHLA-B0.78
154Skin diseaseEnrichmentCOL17A10.72
155Autoinflammatory diseaseEnrichmentSH2D1A0.69
156ScoliosisEnrichmentCOL2A10.69
157Severe covid-19EnrichmentHLA-A0.61
158Stargardt disease 1EnrichmentCOL2A10.60
159Connective tissue diseaseEnrichmentCOL2A10.58
160Systemic lupus erythematosusEnrichmentFCGR2B0.50
161HypertelorismEnrichmentCOL1A10.40
162Frontotemporal dementia and/or amyotrophic lateral sclerosis 7EnrichmentTREM20.37
163Cone-rod dystrophy 2EnrichmentITGA40.32
164Hereditary retinal dystrophyEnrichmentCOL2A1, ITGA40.11
165Fundus dystrophyEnrichmentCOL2A1, ITGA40.11

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