Impaired BRCA2 binding to SEM1 (DSS1)

No Pathway Network information available for Impaired BRCA2 binding to SEM1 (DSS1)

Pathways in the Impaired BRCA2 binding to SEM1 (DSS1) SuperPath

#	Name	Source	Genes
1	Impaired BRCA2 binding to SEM1 (DSS1)	Reactome	BRCA2 SEM1
2	Impaired BRCA2 translocation to the nucleus	Reactome	BRCA2 SEM1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BRCA2	BRCA2 DNA Repair Associated	Protein Coding	2
2	SEM1	SEM1 26S Proteasome Subunit	Protein Coding	2

Disorders associated with Impaired BRCA2 binding to SEM1 (DSS1) SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Glioma susceptibility 3	Enrichment	BRCA2	3.83
2	Pancreatic cancer 2	Enrichment	BRCA2	3.83
3	Diffuse midline glioma, h3 k27m-mutant	Enrichment	BRCA2	3.53
4	Fanconi anemia, complementation group d1	Enrichment	BRCA2	3.53
5	Inflammatory breast carcinoma	Enrichment	BRCA2	3.53
6	Bilateral breast cancer	Enrichment	BRCA2	3.53
7	Neuroendocrine tumor of pancreas	Enrichment	BRCA2	3.53
8	Tumor predisposition syndrome 1	Enrichment	BRCA2	3.35
9	Bap1 tumor predisposition syndrome	Enrichment	BRCA2	3.35
10	Chordoma	Enrichment	BRCA2	3.23
11	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA2	3.23
12	Cholangiocarcinoma	Enrichment	BRCA2	3.23
13	Breast-ovarian cancer, familial 2	Enrichment	BRCA2	3.13
14	Kabuki syndrome 1	Enrichment	BRCA2	3.05
15	Isolated growth hormone deficiency, type ia	Enrichment	BRCA2	2.93
16	Isolated split hand-split foot malformation	Enrichment	SEM1	2.93
17	Tracheoesophageal fistula with or without esophageal atresia	Enrichment	BRCA2	2.88
18	Polydactyly	Enrichment	BRCA2	2.88
19	Isolated tracheo-esophageal fistula	Enrichment	BRCA2	2.83
20	Uterine corpus cancer	Enrichment	BRCA2	2.79
21	Familial colorectal cancer type x	Enrichment	BRCA2	2.79
22	Breast-ovarian cancer, familial 1	Enrichment	BRCA2	2.72
23	Medulloblastoma	Enrichment	BRCA2	2.69
24	Wilms tumor 1	Enrichment	BRCA2	2.66
25	Rhabdomyosarcoma	Enrichment	BRCA2	2.63
26	Diffuse large b-cell lymphoma	Enrichment	BRCA2	2.55
27	Esophageal atresia/tracheoesophageal fistula	Enrichment	BRCA2	2.55
28	Endometrial cancer	Enrichment	BRCA2	2.51
29	Hepatoblastoma	Enrichment	BRCA2	2.51
30	Pancreatic cancer	Enrichment	BRCA2	2.43
31	Bladder cancer	Enrichment	BRCA2	2.37
32	Prostate cancer	Enrichment	BRCA2	2.37
33	Fanconi anemia, complementation group a	Enrichment	BRCA2	2.29
34	Cerebral palsy	Enrichment	BRCA2	2.24
35	Gastric cancer	Enrichment	BRCA2	2.20
36	Hereditary breast carcinoma	Enrichment	BRCA2	2.19
37	Hereditary breast ovarian cancer syndrome	Enrichment	BRCA2	2.09
38	Myeloma, multiple	Enrichment	BRCA2	2.08
39	Breast cancer	Enrichment	BRCA2	1.96
40	Colorectal cancer	Enrichment	BRCA2	1.89
41	Ovarian cancer	Enrichment	BRCA2	1.83
42	Inherited cancer-predisposing syndrome	Enrichment	BRCA2	1.71

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Impaired BRCA2 binding to SEM1 (DSS1)

Pathway Network for Impaired BRCA2 binding to SEM1 (DSS1)

Member Pathways for Impaired BRCA2 binding to SEM1 (DSS1)

Pathways in the Impaired BRCA2 binding to SEM1 (DSS1) SuperPath

Associated Genes for Impaired BRCA2 binding to SEM1 (DSS1)

Associated Disorders for Impaired BRCA2 binding to SEM1 (DSS1)

Disorders associated with Impaired BRCA2 binding to SEM1 (DSS1) SuperPath

STRING Interaction Network for Impaired BRCA2 binding to SEM1 (DSS1)

Sources for Impaired BRCA2 binding to SEM1 (DSS1)