Inclusion body myositis

No Pathway Network information available for Inclusion body myositis

Pathways in the Inclusion body myositis SuperPath

#	Name	Source	Genes
1	Inclusion body myositis	WikiPathways	BACE1 MAPT MSTN NCSTN NFKB1 NFKB2 PSEN1 PSEN2 PSENEN SIRT1 (see all 10) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PSEN2	Presenilin 2	Protein Coding	1
2	PSEN1	Presenilin 1	Protein Coding	1
3	PSENEN	Presenilin Enhancer, Gamma-Secretase Subunit	Protein Coding	1
4	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
5	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
6	MAPT	Microtubule Associated Protein Tau	Protein Coding	1
7	MSTN	Myostatin	Protein Coding	1
8	BACE1	Beta-Secretase 1	Protein Coding	1
9	SIRT1	Sirtuin 1	Protein Coding	1
10	NCSTN	Nicastrin	Protein Coding	1

Disorders associated with Inclusion body myositis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pick disease of brain	Enrichment	MAPT, PSEN1	6.31
2	Alzheimer disease 4	Enrichment	PSEN1, PSEN2	5.83
3	Dementia	Enrichment	MAPT, PSEN1	5.31
4	Semantic dementia	Enrichment	MAPT, PSEN1	4.99
5	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	4.99
6	Early-onset autosomal dominant alzheimer disease	Enrichment	PSEN1, PSEN2	4.99
7	Progressive non-fluent aphasia	Enrichment	MAPT, PSEN1	4.76
8	Behavioral variant of frontotemporal dementia	Enrichment	MAPT, PSEN1	4.76
9	Frontotemporal dementia 1	Enrichment	MAPT, PSEN1	4.57
10	Alzheimer's disease	Enrichment	MAPT, PSEN1	4.42
11	Alzheimer disease, familial, 1	Enrichment	MAPT, PSEN1	4.18
12	Familial isolated dilated cardiomyopathy	Enrichment	PSEN1, PSEN2	3.18
13	Acne inversa, familial, 1	Enrichment	NCSTN	3.13
14	Parkinson-dementia syndrome	Enrichment	MAPT	3.13
15	Supranuclear palsy, progressive, 1	Enrichment	MAPT	3.13
16	Cardiomyopathy, dilated, 1v	Enrichment	PSEN2	3.13
17	Progressive supranuclear palsy	Enrichment	MAPT	3.13
18	Cardiomyopathy, dilated, 1u	Enrichment	PSEN1	3.13
19	Acne inversa, familial, 2, with or without dowling-degos disease	Enrichment	PSENEN	3.13
20	Acne inversa, familial, 3	Enrichment	PSEN1	3.13
21	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	3.13
22	Classic progressive supranuclear palsy syndrome	Enrichment	MAPT	3.13
23	Atypical progressive supranuclear palsy syndrome	Enrichment	MAPT	3.13
24	Pash syndrome	Enrichment	NCSTN	3.13
25	Huntington's disease-like	Enrichment	PSEN2	3.13
26	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	MAPT, PSEN1	3.10
27	Alzheimer disease 3	Enrichment	PSEN1	2.83
28	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.83
29	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.83
30	Muscle hypertrophy	Enrichment	MSTN	2.83
31	Myostatin-related muscle hypertrophy	Enrichment	MSTN	2.83
32	Common variable immunodeficiency 12	Enrichment	NFKB1	2.83
33	Immunodeficiency, common variable, 1	Enrichment	NFKB2	2.53
34	Dowling-degos disease	Enrichment	PSENEN	2.53
35	Telangiectasia, hereditary hemorrhagic, type 1	Enrichment	PSEN1	2.35
36	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	2.13
37	Skin disease	Enrichment	NCSTN	1.79
38	Parkinson disease, late-onset	Enrichment	MAPT	1.76
39	Congenital nervous system abnormality	Enrichment	PSEN1	1.12
40	Nervous system disease	Enrichment	PSEN1	1.12

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Inclusion body myositis

Pathway Network for Inclusion body myositis

Member Pathways for Inclusion body myositis

Pathways in the Inclusion body myositis SuperPath

Associated Genes for Inclusion body myositis

Associated Disorders for Inclusion body myositis

Disorders associated with Inclusion body myositis SuperPath

STRING Interaction Network for Inclusion body myositis

Sources for Inclusion body myositis