Inflammatory bowel disease signaling

No Pathway Network information available for Inflammatory bowel disease signaling

Pathways in the Inflammatory bowel disease signaling SuperPath

#	Name	Source	Genes
1	Inflammatory bowel disease signaling	WikiPathways	FOXP3 GATA3 IFNG IFNGR1 IL10 IL12A IL12RB1 IL12RB2 IL13 IL17F IL18 IL18RAP IL1A IL2 IL21 IL21R IL22 IL23A IL23R IL2RG IL4 IL4R IL5 IL6 JUN MAF NFATC1 NFKB1 NOD2 RORA RORC SMAD2 STAT1 STAT3 STAT4 STAT6 TBX21 TGFB1 TLR2 TLR4 TLR5 TNF (see all 42) (see less)
2	Ulcerative colitis signaling	WikiPathways	FOXP3 GATA3 HLA-DMA IFNG IL10 IL13 IL2RG IL4 IL5 MAF NFATC1 NFKB1 NOD2 STAT6 TGFB1 TLR2 TNF (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TNF	Tumor Necrosis Factor	Protein Coding	2
2	TLR2	Toll Like Receptor 2	Protein Coding	2
3	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	2
4	STAT6	Signal Transducer And Activator Of Transcription 6	Protein Coding	2
5	NOD2	Nucleotide Binding Oligomerization Domain Containing 2	Protein Coding	2
6	FOXP3	Forkhead Box P3~Name Same As:- HGNC:13781	Protein Coding	2
7	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
8	MAF	MAF BZIP Transcription Factor	Protein Coding	2
9	IL13	Interleukin 13	Protein Coding	2
10	IL10	Interleukin 10	Protein Coding	2
11	IL5	Interleukin 5	Protein Coding	2
12	IL4	Interleukin 4	Protein Coding	2
13	IL2RG	Interleukin 2 Receptor Subunit Gamma	Protein Coding	2
14	IFNG	Interferon Gamma	Protein Coding	2
15	GATA3	GATA Binding Protein 3	Protein Coding	2
16	NFATC1	Nuclear Factor Of Activated T Cells 1	Protein Coding	2
17	IL18RAP	Interleukin 18 Receptor Accessory Protein	Protein Coding	1
18	TLR5	Toll Like Receptor 5	Protein Coding	1
19	TLR4	Toll Like Receptor 4	Protein Coding	1
20	STAT4	Signal Transducer And Activator Of Transcription 4	Protein Coding	1
21	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
22	STAT1	Signal Transducer And Activator Of Transcription 1	Protein Coding	1
23	RORC	RAR Related Orphan Receptor C	Protein Coding	1
24	RORA	RAR Related Orphan Receptor A	Protein Coding	1
25	IL21	Interleukin 21	Protein Coding	1
26	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	1
27	IL22	Interleukin 22	Protein Coding	1
28	IL21R	Interleukin 21 Receptor	Protein Coding	1
29	SMAD2	SMAD Family Member 2	Protein Coding	1
30	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
31	IL18	Interleukin 18	Protein Coding	1
32	IL12RB2	Interleukin 12 Receptor Subunit Beta 2	Protein Coding	1
33	IL12RB1	Interleukin 12 Receptor Subunit Beta 1	Protein Coding	1
34	IL12A	Interleukin 12A	Protein Coding	1
35	IL6	Interleukin 6	Protein Coding	1
36	IL4R	Interleukin 4 Receptor	Protein Coding	1
37	IL2	Interleukin 2	Protein Coding	1
38	IL1A	Interleukin 1 Alpha	Protein Coding	1
39	IFNGR1	Interferon Gamma Receptor 1	Protein Coding	1
40	TBX21	T-Box Transcription Factor 21	Protein Coding	1
41	IL23R	Interleukin 23 Receptor	Protein Coding	1
42	IL17F	Interleukin 17F	Protein Coding	1
43	HLA-DMA	Major Histocompatibility Complex, Class II, DM Alpha	Protein Coding	1

Disorders associated with Inflammatory bowel disease signaling SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Behcet syndrome	Enrichment	IFNGR1, IL10, IL12A, IL23R, NOD2, STAT4, TLR4	10.48
2	Immunodeficiency 31c	Enrichment	IL21R, STAT1	5.03
3	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10, TGFB1	4.66
4	Asthma	Enrichment	IL13, TNF	4.09
5	Type 1 diabetes mellitus	Enrichment	FOXP3, IL6	3.86
6	Chronic mucocutaneous candidiasis	Enrichment	IL17F, STAT1	3.86
7	Human immunodeficiency virus type 1	Enrichment	IFNG, IL10	3.65
8	Systemic lupus erythematosus	Enrichment	IL10, STAT4, TNF	3.63
9	Inflammatory bowel disease 1	Enrichment	IL6, NOD2	3.48
10	Primary biliary cholangitis	Enrichment	IL12A, IL12RB1	3.48
11	Leprosy 3	Enrichment	TLR2	2.90
12	Immunodysregulation, polyendocrinopathy, and enteropathy, x-linked	Enrichment	FOXP3	2.90
13	Cataract 21, multiple types	Enrichment	MAF	2.90
14	Blau syndrome	Enrichment	NOD2	2.90
15	Immunodeficiency 69	Enrichment	IFNG	2.90
16	Hyper-ige syndrome 6, autosomal dominant, with recurrent infections	Enrichment	STAT6	2.90
17	Graft-versus-host disease	Enrichment	IL10	2.90
18	Ayme-gripp syndrome	Enrichment	MAF	2.90
19	Allergic rhinitis	Enrichment	IL13	2.90
20	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	2.60
21	Camurati-engelmann disease 1	Enrichment	TGFB1	2.60
22	Multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly	Enrichment	FOXP3	2.60
23	Hemangiopericytoma, malignant	Enrichment	STAT6	2.60
24	Developmental and epileptic encephalopathy 28	Enrichment	MAF	2.60
25	Yao syndrome	Enrichment	NOD2	2.60
26	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.60
27	Spinocerebellar ataxia, autosomal recessive 12	Enrichment	MAF	2.60
28	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.60
29	Immunodeficiency 127	Enrichment	TNF	2.60
30	Camurati-engelmann disease	Enrichment	TGFB1	2.60
31	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	2.60
32	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	2.60
33	Crohn's disease	Enrichment	NOD2	2.60
34	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	2.60
35	Common variable immunodeficiency 12	Enrichment	NFKB1	2.60
36	Helicobacter pylori infection	Enrichment	IFNGR1	2.51
37	Legionnaire disease	Enrichment	TLR5	2.51
38	Immunodeficiency 30	Enrichment	IL12RB1	2.51
39	Candidiasis, familial, 6	Enrichment	IL17F	2.51
40	Immunodeficiency 27a	Enrichment	IFNGR1	2.51
41	Disabling pansclerotic morphea of childhood	Enrichment	STAT4	2.51
42	Systemic lupus erythematosus 1	Enrichment	TLR5	2.51
43	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.51
44	Systemic lupus erythematosus 11	Enrichment	STAT4	2.51
45	Immunodeficiency 42	Enrichment	RORC	2.51
46	Immunodeficiency 27b	Enrichment	IFNGR1	2.51
47	Psoriasis 7	Enrichment	IL23R	2.51
48	Immunodeficiency 31a	Enrichment	STAT1	2.51
49	Melioidosis	Enrichment	TLR5	2.51
50	Loeys-dietz syndrome 6	Enrichment	SMAD2	2.51
51	Inflammatory bowel disease 17	Enrichment	IL23R	2.51
52	Macular degeneration, age-related, 10	Enrichment	TLR4	2.51
53	Immunodeficiency 31b	Enrichment	STAT1	2.51
54	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.51
55	Immunodeficiency 88	Enrichment	TBX21	2.51
56	Congenital heart defects, multiple types, 8, with or without heterotaxy	Enrichment	SMAD2	2.51
57	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.51
58	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.51
59	Tuberous sclerosis 1	Enrichment	IFNG	2.43
60	Severe combined immunodeficiency, x-linked	Enrichment	IL2RG	2.43
61	Combined immunodeficiency, x-linked	Enrichment	IL2RG	2.43
62	Psoriatic arthritis	Enrichment	TNF	2.43
63	Hepatitis c virus	Enrichment	IFNG	2.43
64	Tuberous sclerosis 2	Enrichment	IFNG	2.43
65	Migraine without aura	Enrichment	TNF	2.43
66	End stage renal disease	Enrichment	GATA3	2.43
67	Congenital blue dot cataract	Enrichment	MAF	2.30
68	Cerebral malaria	Enrichment	TNF	2.30
69	Immunodeficiency 56	Enrichment	IL21R	2.21
70	Intellectual developmental disorder with or without epilepsy or cerebellar ataxia	Enrichment	RORA	2.21
71	Vascular dementia	Enrichment	TNF	2.20
72	Idiopathic aplastic anemia	Enrichment	IFNG	2.20
73	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	2.13
74	Common variable immunodeficiency	Enrichment	NFKB1	2.06
75	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	2.03
76	Asthma, nasal polyps, and aspirin intolerance	Enrichment	TBX21	2.03
77	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	2.03
78	Hyper ige syndrome	Enrichment	STAT3	2.03
79	Loeys-dietz syndrome 1	Enrichment	SMAD2	2.03
80	Immunodeficiency, common variable, 11	Enrichment	IL21	2.03
81	Cataract - microcornea syndrome	Enrichment	MAF	2.00
82	Rheumatoid arthritis	Enrichment	IL10	1.95
83	Hydrops fetalis	Enrichment	FOXP3	1.95
84	Kaposi sarcoma	Enrichment	IL6	1.91
85	Hepatitis b	Enrichment	IFNGR1	1.91
86	Pediatric systemic lupus erythematosus	Enrichment	STAT4	1.91
87	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.91
88	Cataract 30, multiple types	Enrichment	MAF	1.90
89	Omenn syndrome	Enrichment	IL2RG	1.90
90	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.90
91	Aplastic anemia	Enrichment	IFNG	1.90
92	Combined immunodeficiency	Enrichment	IL2RG	1.86
93	Combined t cell and b cell immunodeficiency	Enrichment	IL2RG	1.86
94	Combined t and b cell immunodeficiency	Enrichment	IL2RG	1.86
95	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.81
96	Alzheimer's disease	Enrichment	TNF	1.79
97	Oligoarticular juvenile idiopathic arthritis	Enrichment	STAT4	1.67
98	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	STAT4	1.67
99	Breast cancer	Enrichment	IL2, JUN	1.65
100	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.61
101	Centronuclear myopathy	Enrichment	FOXP3	1.58
102	Loeys-dietz syndrome	Enrichment	SMAD2	1.56
103	Malaria	Enrichment	TNF	1.55
104	Autoinflammatory disease	Enrichment	NOD2	1.53
105	Developmental and epileptic encephalopathy 1	Enrichment	MAF	1.51
106	Cystic fibrosis	Enrichment	TGFB1	1.40
107	Acute promyelocytic leukemia	Enrichment	STAT3	1.40
108	Cakut	Enrichment	GATA3	1.38
109	Benign epilepsy with centrotemporal spikes	Enrichment	MAF	1.30
110	Centralopathic epilepsy	Enrichment	MAF	1.28
111	West syndrome	Enrichment	MAF	1.27
112	Arteriovenous malformations of the brain	Enrichment	IL6	1.24
113	Diffuse large b-cell lymphoma	Enrichment	STAT3	1.24
114	Colorectal cancer	Enrichment	TLR2	0.98
115	Type 2 diabetes mellitus	Enrichment	IL6	0.91
116	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	SMAD2	0.89
117	Complex neurodevelopmental disorder	Enrichment	RORA	0.49

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Inflammatory bowel disease signaling

Pathway Network for Inflammatory bowel disease signaling

Member Pathways for Inflammatory bowel disease signaling

Pathways in the Inflammatory bowel disease signaling SuperPath

Associated Genes for Inflammatory bowel disease signaling

Associated Disorders for Inflammatory bowel disease signaling

Disorders associated with Inflammatory bowel disease signaling SuperPath

STRING Interaction Network for Inflammatory bowel disease signaling

Sources for Inflammatory bowel disease signaling