Inhibitory action of Lipoxins on Superoxide production in neutrophils

No Pathway Network information available for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Pathways in the Inhibitory action of Lipoxins on Superoxide production in neutrophils SuperPath

#	Name	Source	Genes
1	Inhibitory action of Lipoxins on Superoxide production in neutrophils	GeneGo (Thomson Reuters)	CXCL8 CXCR1 CYBA CYBB FPR2 GNA15 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 ITPR1 ITPR2 ITPR3 LTB4R NCF1 NCF2 NCF4 PAK1 PDPK1 PIK3CG PIK3R5 PLCB2 PLD1 PLPP6 PREX1 PRKCA PRKCZ RAC2 (see all 46) (see less)
2	Inhibitory action of Lipoxins and Resolvin E1 on neutrophil functions	GeneGo (Thomson Reuters)	CFTR CHUK CXCL8 FOS FPR2 GNAI1 GNAI2 GNAI3 GNAO1 GNAZ GNB1 GNB2 GNB3 GNB4 GNB5 GNG10 GNG11 GNG12 GNG13 GNG2 GNG3 GNG4 GNG5 GNG7 GNG8 GNGT1 GNGT2 JUN LTB4R MAP3K14 MAPK1 MAPK3 NFKB1 NFKB2 NFKBIA NFKBIB NFKBIE PIK3CG PIK3R5 PLD1 PLPP6 PRKCZ REL RELA RELB SOD1 (see all 46) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LTB4R	Leukotriene B4 Receptor	Protein Coding	2
2	FPR2	Formyl Peptide Receptor 2	Protein Coding	2
3	GNAI1	G Protein Subunit Alpha I1	Protein Coding	2
4	GNAI2	G Protein Subunit Alpha I2	Protein Coding	2
5	GNAI3	G Protein Subunit Alpha I3	Protein Coding	2
6	GNAO1	G Protein Subunit Alpha O1	Protein Coding	2
7	GNAZ	G Protein Subunit Alpha Z	Protein Coding	2
8	GNB1	G Protein Subunit Beta 1	Protein Coding	2
9	GNB2	G Protein Subunit Beta 2	Protein Coding	2
10	GNB3	G Protein Subunit Beta 3	Protein Coding	2
11	GNG3	G Protein Subunit Gamma 3	Protein Coding	2
12	GNG4	G Protein Subunit Gamma 4	Protein Coding	2
13	GNG5	G Protein Subunit Gamma 5	Protein Coding	2
14	GNG7	G Protein Subunit Gamma 7	Protein Coding	2
15	GNG10	G Protein Subunit Gamma 10	Protein Coding	2
16	GNG11	G Protein Subunit Gamma 11	Protein Coding	2
17	GNGT1	G Protein Subunit Gamma Transducin 1	Protein Coding	2
18	GNGT2	G Protein Subunit Gamma Transducin 2	Protein Coding	2
19	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	2
20	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	2
21	PLD1	Phospholipase D1	Protein Coding	2
22	PRKCZ	Protein Kinase C Zeta	Protein Coding	2
23	GNB5	G Protein Subunit Beta 5	Protein Coding	2
24	PIK3R5	Phosphoinositide-3-Kinase Regulatory Subunit 5	Protein Coding	2
25	GNG13	G Protein Subunit Gamma 13	Protein Coding	2
26	GNG2	G Protein Subunit Gamma 2	Protein Coding	2
27	GNG12	G Protein Subunit Gamma 12	Protein Coding	2
28	GNB4	G Protein Subunit Beta 4	Protein Coding	2
29	GNG8	G Protein Subunit Gamma 8	Protein Coding	2
30	PLPP6	Phospholipid Phosphatase 6	Protein Coding	2
31	CYBA	Cytochrome B-245 Alpha Chain	Protein Coding	1
32	CYBB	Cytochrome B-245 Beta Chain	Protein Coding	1
33	GNA15	G Protein Subunit Alpha 15	Protein Coding	1
34	CXCR1	C-X-C Motif Chemokine Receptor 1	Protein Coding	1
35	ITPR1	Inositol 1,4,5-Trisphosphate Receptor Type 1	Protein Coding	1
36	ITPR2	Inositol 1,4,5-Trisphosphate Receptor Type 2	Protein Coding	1
37	ITPR3	Inositol 1,4,5-Trisphosphate Receptor Type 3	Protein Coding	1
38	NCF2	Neutrophil Cytosolic Factor 2	Protein Coding	1
39	NCF4	Neutrophil Cytosolic Factor 4	Protein Coding	1
40	PAK1	P21 (RAC1) Activated Kinase 1	Protein Coding	1
41	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	1
42	PLCB2	Phospholipase C Beta 2	Protein Coding	1
43	PRKCA	Protein Kinase C Alpha	Protein Coding	1
44	RAC2	Rac Family Small GTPase 2	Protein Coding	1
45	PREX1	Phosphatidylinositol-3,4,5-Trisphosphate Dependent Rac Exchange Factor 1	Protein Coding	1
46	NCF1	Neutrophil Cytosolic Factor 1	Protein Coding	1
47	CFTR	CF Transmembrane Conductance Regulator	Protein Coding	1
48	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
49	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
50	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
51	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
52	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
53	NFKBIA	NFKB Inhibitor Alpha	Protein Coding	1
54	NFKBIB	NFKB Inhibitor Beta	Protein Coding	1
55	NFKBIE	NFKB Inhibitor Epsilon	Protein Coding	1
56	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
57	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
58	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
59	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
60	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
61	SOD1	Superoxide Dismutase 1	Protein Coding	1
62	MAP3K14	Mitogen-Activated Protein Kinase Kinase Kinase 14	Protein Coding	1

Disorders associated with Inhibitory action of Lipoxins on Superoxide production in neutrophils SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Chronic granulomatous disease	Enrichment	CYBA, CYBB, NCF1, NCF2, NCF4	10.25
2	Granulomatous disease, chronic, autosomal recessive, 2	Enrichment	NCF1, NCF2	4.47
3	Granulomatous disease, chronic, x-linked	Enrichment	CYBB, NCF1	4.17
4	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	3.63
5	Anhidrosis, isolated, with normal sweat glands	Enrichment	ITPR2	2.47
6	Granulomatous disease, chronic, autosomal recessive, 4	Enrichment	CYBA	2.47
7	Immunodeficiency 34	Enrichment	CYBB	2.47
8	Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosis	Enrichment	RAC2	2.47
9	Cardiac valvular dysplasia 1	Enrichment	PLD1	2.47
10	Neurodevelopmental disorder with involuntary movements	Enrichment	GNAO1	2.47
11	Ataxia-oculomotor apraxia 3	Enrichment	PIK3R5	2.47
12	Ventricular tachycardia, familial	Enrichment	GNAI2	2.47
13	Neurodevelopmental disorder with hypotonia and dysmorphic facies	Enrichment	GNB2	2.47
14	Charcot-marie-tooth disease, demyelinating, type 1j	Enrichment	ITPR3	2.47
15	Intellectual developmental disorder with macrocephaly, seizures, and speech delay	Enrichment	PAK1	2.47
16	Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemia	Enrichment	RAC2	2.47
17	Neurodevelopmental disorder with hypotonia, impaired speech, and behavioral abnormalities	Enrichment	GNAI1	2.47
18	Developmental and epileptic encephalopathy 17	Enrichment	GNAO1	2.47
19	Lodder-merla syndrome, type 2, with developmental delay and with or without cardiac arrhythmia	Enrichment	GNB5	2.47
20	Charcot-marie-tooth disease, dominant intermediate f	Enrichment	GNB4	2.47
21	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.47
22	Intellectual developmental disorder, autosomal dominant 42	Enrichment	GNB1	2.47
23	Sick sinus syndrome 4	Enrichment	GNB2	2.47
24	Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopenia	Enrichment	RAC2	2.47
25	Immunodeficiency 133 with ectodermal dysplasia with or without peripheral neuropathy	Enrichment	ITPR3	2.47
26	Infantile lad-like disease due to rac2 deficiency	Enrichment	RAC2	2.47
27	Reticular dysgenesis-like severe combined immunodeficiency	Enrichment	RAC2	2.47
28	Gnao1-related disorder	Enrichment	GNAO1	2.47
29	Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndrome	Enrichment	RAC2	2.47
30	Fetal encasement syndrome	Enrichment	CHUK	2.47
31	Noonan syndrome 13	Enrichment	MAPK1	2.47
32	Immunodeficiency 92	Enrichment	REL	2.47
33	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.47
34	Immunodeficiency 53	Enrichment	RELB	2.47
35	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.47
36	Immunodeficiency 112	Enrichment	MAP3K14	2.47
37	Aquagenic palmoplantar keratoderma	Enrichment	CFTR	2.47
38	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.47
39	Nik deficiency	Enrichment	MAP3K14	2.47
40	Spinocerebellar ataxia 29	Enrichment	ITPR1	2.17
41	Granulomatous disease, chronic, autosomal recessive, 1	Enrichment	NCF1	2.17
42	Pituitary adenoma 4, acth-secreting	Enrichment	GNAI2	2.17
43	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	PIK3R5	2.17
44	Granulomatous disease, chronic, autosomal recessive, 3	Enrichment	NCF4	2.17
45	Night blindness, congenital stationary, type 1h	Enrichment	GNB3	2.17
46	Hypopituitarism	Enrichment	GNAI2	2.17
47	Lodder-merla syndrome, type 1, with impaired intellectual development and cardiac arrhythmia	Enrichment	GNB5	2.17
48	Cerebral visual impairment	Enrichment	GNB1	2.17
49	Spermatogenic failure, y-linked, 2	Enrichment	CFTR	2.17
50	Ectodermal dysplasia and immunodeficiency 2	Enrichment	NFKBIA	2.17
51	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.17
52	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.17
53	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.17
54	Rela fusion-positive ependymoma	Enrichment	RELA	2.17
55	Ectodermal dysplasia and immune deficiency	Enrichment	NFKBIA	2.17
56	Spastic tetraplegia and axial hypotonia, progressive	Enrichment	SOD1	2.17
57	Common variable immunodeficiency 12	Enrichment	NFKB1	2.17
58	Microcephaly	Enrichment	GNAO1, GNB1, MAPK1	2.08
59	Autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasia	Enrichment	CYBA	1.99
60	Gillespie syndrome	Enrichment	ITPR1	1.99
61	Autoimmune polyendocrine syndrome type 1	Enrichment	CYBA	1.99
62	Nuchal bleb, familial	Enrichment	CFTR	1.99
63	Nasopharyngeal carcinoma	Enrichment	NFKBIA	1.99
64	Spastic paraplegia 17, autosomal dominant	Enrichment	GNG3	1.87
65	Auriculocondylar syndrome 1	Enrichment	GNAI3	1.87
66	Lipodystrophy, congenital generalized, type 2	Enrichment	GNG3	1.87
67	Spinocerebellar ataxia 15	Enrichment	ITPR1	1.87
68	Achromatopsia 4	Enrichment	GNAI3	1.87
69	Familial sick sinus syndrome	Enrichment	GNB2	1.87
70	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.87
71	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.87
72	Congenital generalized lipodystrophy	Enrichment	FOS	1.87
73	Idiopathic bronchiectasis	Enrichment	CFTR	1.87
74	Amyotrophic lateral sclerosis 10 with or without frontotemporal dementia	Enrichment	SOD1	1.77
75	Histiocytoid hemangioma	Enrichment	FOS	1.77
76	Spinocerebellar ataxia, autosomal recessive 16	Enrichment	ITPR1	1.70
77	Motor neuron disease	Enrichment	SOD1	1.63
78	Breast cancer	Enrichment	GNG3, JUN	1.57
79	Hypothyroidism	Enrichment	GNB1	1.57
80	Choreatic disease	Enrichment	GNAO1	1.57
81	Cardiomyopathy, familial hypertrophic, 4	Enrichment	NCF1	1.52
82	Bronchiectasis with or without elevated sweat chloride 1	Enrichment	CFTR	1.52
83	Vas deferens, congenital bilateral aplasia of	Enrichment	CFTR	1.52
84	Amyotrophic lateral sclerosis 1	Enrichment	SOD1	1.48
85	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.48
86	Leukemia, acute lymphoblastic	Enrichment	GNB1	1.44
87	Myelodysplastic syndrome	Enrichment	GNB1	1.44
88	Movement disease	Enrichment	GNAO1	1.44
89	Specific learning disability	Enrichment	MAPK1	1.44
90	Congenital long qt syndrome	Enrichment	ITPR3	1.40
91	Chromosome 1p36 deletion syndrome	Enrichment	PRKCZ	1.36
92	Multiple sclerosis	Enrichment	ITPR1	1.33
93	Hereditary chronic pancreatitis	Enrichment	CFTR	1.33
94	Anterior segment dysgenesis	Enrichment	ITPR1	1.30
95	Rare genetic intellectual disability	Enrichment	GNAO1	1.30
96	Lynch syndrome	Enrichment	CFTR	1.30
97	Congenital nervous system abnormality	Enrichment	GNAO1, GNB5	1.30
98	Nervous system disease	Enrichment	GNAO1, GNB5	1.30
99	Gliosarcoma	Enrichment	NFKBIA	1.28
100	Hypertension, essential	Enrichment	GNB3	1.25
101	Cleft palate, isolated	Enrichment	GNB1	1.25
102	Pancreatitis, hereditary	Enrichment	CFTR	1.25
103	Giant cell glioblastoma	Enrichment	NFKBIA	1.25
104	Human immunodeficiency virus type 1	Enrichment	CXCR1	1.23
105	Early infantile developmental and epileptic encephalopathy	Enrichment	GNAO1	1.23
106	Heart, malformation of	Enrichment	MAPK1	1.23
107	Williams-beuren syndrome	Enrichment	NCF1	1.18
108	Attention deficit-hyperactivity disorder	Enrichment	GNB5	1.14
109	Congenital stationary night blindness	Enrichment	GNB3	1.12
110	Developmental and epileptic encephalopathy 1	Enrichment	GNAO1	1.09
111	Strabismus	Enrichment	GNB1	1.06
112	Long qt syndrome 1	Enrichment	ITPR3	1.01
113	Cystic fibrosis	Enrichment	CFTR	0.99
114	Male infertility	Enrichment	CFTR	0.96
115	Dystonia	Enrichment	GNB1	0.95
116	Developmental and epileptic encephalopathy	Enrichment	GNAO1	0.94
117	Cerebral palsy	Enrichment	GNB1	0.91
118	West syndrome	Enrichment	GNAO1	0.86
119	Autosomal dominant non-syndromic intellectual disability	Enrichment	GNB1	0.81
120	Spastic ataxia	Enrichment	ITPR1	0.78
121	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	CFTR	0.76
122	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	SOD1	0.75
123	Autism spectrum disorder	Enrichment	GNB1	0.51
124	Complex neurodevelopmental disorder	Enrichment	GNB2	0.46

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Inhibitory action of Lipoxins on Superoxide production in neutrophils

Pathway Network for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Member Pathways for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Pathways in the Inhibitory action of Lipoxins on Superoxide production in neutrophils SuperPath

Associated Genes for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Associated Disorders for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Disorders associated with Inhibitory action of Lipoxins on Superoxide production in neutrophils SuperPath

STRING Interaction Network for Inhibitory action of Lipoxins on Superoxide production in neutrophils

Sources for Inhibitory action of Lipoxins on Superoxide production in neutrophils