Innate Lymphoid Cells Differentiation

No Pathway Network information available for Innate Lymphoid Cells Differentiation

Pathways in the Innate Lymphoid Cells Differentiation SuperPath

#	Name	Source	Genes
1	Innate Lymphoid Cells Differentiation	R&D Systems	AHR CCL3 CCR6 CD101 CD160 CD244 CD34 CD4 CD44 CD7 CD8A CD93 CRLF2 CXCR3 CXCR5 CXCR6 EOMES ETS1 GAGE6 GATA3 GZMA GZMB GZMH ICOS ID2 IFI6 IFNG IKZF1 IL10 IL12A IL12RB1 IL12RB2 IL13 IL15 IL15RA IL17A IL17RB IL18 IL1B IL1R1 IL1RL1 IL2 IL22 IL23A IL23R IL25 IL2RA IL2RB IL33 IL4 IL5 IL7 IL7R IL9 IRF4 ITGA4 ITGAE ITGAM KIT KLRB1 KLRD1 KLRK1 LTA LTB NCAM1 NCR1 NCR2 NOTCH2 PDE2A PTGDR2 PTPRC RORC RUNX1 SPI1 TBX21 THY1 TNF TPP1 TSLP ZBTB16 (see all 80) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	IKZF1	IKAROS Family Zinc Finger 1	Protein Coding	1
2	ID2	Inhibitor Of DNA Binding 2	Protein Coding	1
3	NOTCH2	Notch Receptor 2	Protein Coding	1
4	ZBTB16	Zinc Finger And BTB Domain Containing 16	Protein Coding	1
5	ITGA4	Integrin Subunit Alpha 4	Protein Coding	1
6	IL7	Interleukin 7	Protein Coding	1
7	IL15	Interleukin 15	Protein Coding	1
8	CD7	CD7 Molecule	Protein Coding	1
9	CD8A	CD8 Subunit Alpha	Protein Coding	1
10	CD34	CD34 Molecule	Protein Coding	1
11	IL2RB	Interleukin 2 Receptor Subunit Beta	Protein Coding	1
12	KLRB1	Killer Cell Lectin Like Receptor B1	Protein Coding	1
13	IL2	Interleukin 2	Protein Coding	1
14	IL12A	Interleukin 12A	Protein Coding	1
15	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
16	SPI1	Spi-1 Proto-Oncogene	Protein Coding	1
17	NCAM1	Neural Cell Adhesion Molecule 1	Protein Coding	1
18	KIT	KIT Proto-Oncogene, Receptor Tyrosine Kinase	Protein Coding	1
19	IL7R	Interleukin 7 Receptor	Protein Coding	1
20	IL18	Interleukin 18	Protein Coding	1
21	TBX21	T-Box Transcription Factor 21	Protein Coding	1
22	EOMES	Eomesodermin	Protein Coding	1
23	NCR1	Natural Cytotoxicity Triggering Receptor 1	Protein Coding	1
24	ITGAM	Integrin Subunit Alpha M	Protein Coding	1
25	THY1	Thy-1 Cell Surface Antigen	Protein Coding	1
26	KLRK1	Killer Cell Lectin Like Receptor K1	Protein Coding	1
27	IL2RA	Interleukin 2 Receptor Subunit Alpha	Protein Coding	1
28	IL12RB2	Interleukin 12 Receptor Subunit Beta 2	Protein Coding	1
29	IFNG	Interferon Gamma	Protein Coding	1
30	TNF	Tumor Necrosis Factor	Protein Coding	1
31	IL10	Interleukin 10	Protein Coding	1
32	IL13	Interleukin 13	Protein Coding	1
33	RORC	RAR Related Orphan Receptor C	Protein Coding	1
34	AHR	Aryl Hydrocarbon Receptor	Protein Coding	1
35	RUNX1	RUNX Family Transcription Factor 1	Protein Coding	1
36	IL1B	Interleukin 1 Beta	Protein Coding	1
37	IL23A	Interleukin 23 Subunit Alpha	Protein Coding	1
38	CD4	CD4 Molecule	Protein Coding	1
39	CXCR5	C-X-C Motif Chemokine Receptor 5	Protein Coding	1
40	CXCR6	C-X-C Motif Chemokine Receptor 6	Protein Coding	1
41	CCR6	C-C Motif Chemokine Receptor 6	Protein Coding	1
42	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	1
43	IL23R	Interleukin 23 Receptor	Protein Coding	1
44	IL17A	Interleukin 17A	Protein Coding	1
45	IL22	Interleukin 22	Protein Coding	1
46	LTA	Lymphotoxin Alpha	Protein Coding	1
47	LTB	Lymphotoxin Beta	Protein Coding	1
48	GATA3	GATA Binding Protein 3	Protein Coding	1
49	CD93	CD93 Molecule	Protein Coding	1
50	CD244	CD244 Molecule	Protein Coding	1
51	IFI6	Interferon Alpha Inducible Protein 6	Protein Coding	1
52	IL25	Interleukin 25	Protein Coding	1
53	IL33	Interleukin 33	Protein Coding	1
54	TSLP	Thymic Stromal Lymphopoietin	Protein Coding	1
55	PTPRC	Protein Tyrosine Phosphatase Receptor Type C	Protein Coding	1
56	IL17RB	Interleukin 17 Receptor B	Protein Coding	1
57	IL1RL1	Interleukin 1 Receptor Like 1	Protein Coding	1
58	CRLF2	Cytokine Receptor Like Factor 2	Protein Coding	1
59	PTGDR2	Prostaglandin D2 Receptor 2	Protein Coding	1
60	ICOS	Inducible T Cell Costimulator	Protein Coding	1
61	PDE2A	Phosphodiesterase 2A	Protein Coding	1
62	NCR2	Natural Cytotoxicity Triggering Receptor 2	Protein Coding	1
63	GAGE6	G Antigen 6	Protein Coding	1
64	KLRD1	Killer Cell Lectin Like Receptor D1	Protein Coding	1
65	CXCR3	C-X-C Motif Chemokine Receptor 3	Protein Coding	1
66	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	1
67	IL15RA	Interleukin 15 Receptor Subunit Alpha	Protein Coding	1
68	TPP1	Tripeptidyl Peptidase 1	Protein Coding	1
69	IRF4	Interferon Regulatory Factor 4	Protein Coding	1
70	CD101	CD101 Molecule	Protein Coding	1
71	ITGAE	Integrin Subunit Alpha E	Protein Coding	1
72	CD160	CD160 Molecule	Protein Coding	1
73	IL12RB1	Interleukin 12 Receptor Subunit Beta 1	Protein Coding	1
74	CD44	CD44 Molecule (IN Blood Group)	Protein Coding	1
75	GZMA	Granzyme A	Protein Coding	1
76	GZMB	Granzyme B	Protein Coding	1
77	GZMH	Granzyme H	Protein Coding	1
78	IL4	Interleukin 4	Protein Coding	1
79	IL5	Interleukin 5	Protein Coding	1
80	IL9	Interleukin 9	Protein Coding	1

Disorders associated with Innate Lymphoid Cells Differentiation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Immunodeficiency 104, severe combined	Enrichment	IL7R, PTPRC	4.46
2	Systemic lupus erythematosus	Enrichment	ETS1, IL10, ITGAM, TNF	4.10
3	Psoriatic arthritis	Enrichment	LTA, TNF	3.99
4	Human immunodeficiency virus type 1	Enrichment	CCL3, IFNG, IL10	3.82
5	Behcet syndrome	Enrichment	IL10, IL12A, IL23R	3.75
6	Acute myeloid leukemia with t(8;21)(q22;q22) translocation	Enrichment	KIT, RUNX1	3.47
7	Oligoarticular juvenile idiopathic arthritis	Enrichment	IL2RA, IL2RB	3.15
8	Rheumatoid factor-negative juvenile idiopathic arthritis	Enrichment	IL2RA, IL2RB	3.15
9	Rheumatoid arthritis	Enrichment	CD244, IL10	2.92
10	Primary biliary cholangitis	Enrichment	IL12A, IL12RB1	2.92
11	Asthma	Enrichment	IL13, TNF	2.74
12	Type 1 diabetes mellitus 10	Enrichment	IL2RA	2.23
13	Systemic lupus erythematosus 6	Enrichment	ITGAM	2.23
14	Leprosy 4	Enrichment	LTA	2.23
15	Skin/hair/eye pigmentation, variation in, 8	Enrichment	IRF4	2.23
16	Mastocytosis, cutaneous	Enrichment	KIT	2.23
17	Immunodeficiency 30	Enrichment	IL12RB1	2.23
18	Hajdu-cheney syndrome	Enrichment	NOTCH2	2.23
19	Alagille syndrome 2	Enrichment	NOTCH2	2.23
20	Skeletal defects, genital hypoplasia, and impaired intellectual development	Enrichment	ZBTB16	2.23
21	Spinocerebellar ataxia, autosomal recessive 7	Enrichment	TPP1	2.23
22	Immunodeficiency 116	Enrichment	CD8A	2.23
23	Retinitis pigmentosa 85	Enrichment	AHR	2.23
24	Immunodeficiency 69	Enrichment	IFNG	2.23
25	Agammaglobulinemia 10, autosomal dominant	Enrichment	SPI1	2.23
26	Immunodeficiency 130 with hpv-related verrucosis	Enrichment	IL7	2.23
27	Immunodeficiency 131	Enrichment	IRF4	2.23
28	Immunodeficiency 63 with lymphoproliferation and autoimmunity	Enrichment	IL2RB	2.23
29	Okt4 epitope deficiency	Enrichment	CD4	2.23
30	Graft-versus-host disease	Enrichment	IL10	2.23
31	Foveal hypoplasia 3	Enrichment	AHR	2.23
32	Intellectual developmental disorder with paroxysmal dyskinesia or seizures	Enrichment	PDE2A	2.23
33	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	2.23
34	Allergic rhinitis	Enrichment	IL13	2.23
35	Immunodeficiency 42	Enrichment	RORC	2.23
36	Psoriasis 7	Enrichment	IL23R	2.23
37	Inflammatory bowel disease 17	Enrichment	IL23R	2.23
38	Immunodeficiency 105, severe combined	Enrichment	PTPRC	2.23
39	Immunodeficiency, common variable, 13	Enrichment	IKZF1	2.23
40	Immunodeficiency 79	Enrichment	CD4	2.23
41	Cd45 deficiency	Enrichment	PTPRC	2.23
42	Immunodeficiency 88	Enrichment	TBX21	2.23
43	Chronic mast cell leukemia	Enrichment	KIT	2.23
44	Combined immunodeficiency due to dimerization defective ikaros mutation	Enrichment	IKZF1	2.23
45	Agammaglobulinemia	Enrichment	SPI1	2.23
46	Isolated bone marrow mastocytosis	Enrichment	KIT	2.23
47	Smoldering systemic mastocytosis	Enrichment	KIT	2.23
48	Mastocytosis	Enrichment	KIT	2.23
49	Early-onset combined immunodeficiency with low ig due to dominant negative ikaros mutation	Enrichment	IKZF1	2.23
50	Whipple disease	Enrichment	IRF4	2.23
51	Cutaneous mastocytoma	Enrichment	KIT	2.23
52	Typical urticaria pigmentosa	Enrichment	KIT	2.23
53	T-b+ severe combined immunodeficiency due to il-7ralpha deficiency	Enrichment	IL7R	2.23
54	Nodular urticaria pigmentosa	Enrichment	KIT	2.23
55	Pseudoxanthomatous diffuse cutaneous mastocytosis	Enrichment	KIT	2.23
56	Telangiectasia macularis eruptiva perstans	Enrichment	KIT	2.23
57	Acute mast cell leukemia	Enrichment	KIT	2.23
58	Plaque-form urticaria pigmentosa	Enrichment	KIT	2.23
59	Microcephaly-polymicrogyria-corpus callosum agenesis syndrome	Enrichment	EOMES	2.23
60	Bullous diffuse cutaneous mastocytosis	Enrichment	KIT	2.23
61	Testis seminoma	Enrichment	KIT	2.23
62	Hypoparathyroidism, sensorineural deafness, and renal dysplasia syndrome	Enrichment	GATA3	1.93
63	Storage pool platelet disease	Enrichment	RUNX1	1.93
64	Ceroid lipofuscinosis, neuronal, 2	Enrichment	TPP1	1.93
65	Immunodeficiency 41 with lymphoproliferation and autoimmunity	Enrichment	IL2RA	1.93
66	Piebald trait	Enrichment	KIT	1.93
67	Ceroid lipofuscinosis, neuronal, 3	Enrichment	TPP1	1.93
68	Diamond-blackfan anemia-like	Enrichment	IKZF1	1.93
69	Immunodeficiency 127	Enrichment	TNF	1.93
70	Stevens-johnson syndrome	Enrichment	IKZF1	1.93
71	Multiple sclerosis 3	Enrichment	IL7R	1.93
72	B-lymphoblastic leukemia/lymphoma with hyperdiploidy	Enrichment	GATA3	1.93
73	Hypoparathyroidism-deafness-renal disease syndrome	Enrichment	GATA3	1.93
74	Autosomal dominant nonsyndromic deafness	Enrichment	GATA3	1.93
75	B-lymphoblastic leukemia/lymphoma with t	Enrichment	KIT	1.93
76	Tafro syndrome	Enrichment	RUNX1	1.93
77	Severe combined immunodeficiency	Enrichment	IL7R, PTPRC	1.79
78	Jacobsen syndrome	Enrichment	ETS1	1.75
79	Asthma, nasal polyps, and aspirin intolerance	Enrichment	TBX21	1.75
80	Tuberous sclerosis 1	Enrichment	IFNG	1.75
81	Platelet disorder, familial, with associated myeloid malignancy	Enrichment	RUNX1	1.75
82	Hepatitis c virus	Enrichment	IFNG	1.75
83	Tuberous sclerosis 2	Enrichment	IFNG	1.75
84	Testicular germ cell cancer	Enrichment	KIT	1.75
85	Migraine without aura	Enrichment	TNF	1.75
86	End stage renal disease	Enrichment	GATA3	1.75
87	Hereditary thrombocytopenia and hematological cancer predisposition syndrome associated with runx1	Enrichment	RUNX1	1.75
88	Keratoacanthoma	Enrichment	NOTCH2	1.75
89	Leukemia, acute myeloid	Enrichment	KIT, RUNX1	1.63
90	Immunodeficiency, common variable, 1	Enrichment	ICOS	1.63
91	Retinitis pigmentosa 26	Enrichment	ITGA4	1.63
92	Blood platelet disease	Enrichment	RUNX1	1.63
93	Acute myeloid leukemia with abnormal bone marrow eosinophils inv(16)(p13q22) or t(16;16)(p13;q22)	Enrichment	KIT	1.63
94	Cerebral malaria	Enrichment	TNF	1.63
95	Inherited epidermodysplasia verruciformis	Enrichment	IL7	1.63
96	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	KIT	1.63
97	Hydatidiform mole, recurrent, 1	Enrichment	NCR1	1.54
98	Convulsions, familial infantile, with paroxysmal choreoathetosis	Enrichment	PDE2A	1.54
99	Acute myeloid leukemia with maturation	Enrichment	KIT	1.54
100	Vascular dementia	Enrichment	TNF	1.54
101	Aggressive systemic mastocytosis	Enrichment	RUNX1	1.54
102	Diffuse cutaneous systemic sclerosis	Enrichment	CCR6	1.54
103	Idiopathic aplastic anemia	Enrichment	IFNG	1.54
104	Angelman syndrome	Enrichment	TPP1	1.46
105	Testicular germ cell tumor	Enrichment	KIT	1.46
106	Pancytopenia	Enrichment	RUNX1	1.46
107	Limited scleroderma	Enrichment	CCR6	1.46
108	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.46
109	Gastrointestinal stromal tumor	Enrichment	KIT	1.39
110	Leukemia, chronic myeloid	Enrichment	RUNX1	1.39
111	Paroxysmal dystonia	Enrichment	PDE2A	1.39
112	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	IKZF1	1.39
113	Choreatic disease	Enrichment	PDE2A	1.34
114	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	RUNX1	1.29
115	Omenn syndrome	Enrichment	IL7R	1.24
116	Aplastic anemia	Enrichment	IFNG	1.24
117	Autosomal non-syndromic agammaglobulinemia	Enrichment	SPI1	1.24
118	Immune deficiency disease	Enrichment	IKZF1	1.20
119	Leukemia, acute lymphoblastic	Enrichment	IKZF1	1.20
120	Ichthyosis	Enrichment	IL2RB	1.20
121	Lip and oral cavity carcinoma	Enrichment	KIT	1.16
122	Breast cancer	Enrichment	IL2, IL7R	1.14
123	Acute promyelocytic leukemia	Enrichment	ZBTB16	1.13
124	Alzheimer's disease	Enrichment	TNF	1.13
125	Isolated macular dystrophy	Enrichment	ITGA4	1.10
126	Neuronal ceroid lipofuscinosis	Enrichment	TPP1	1.07
127	Myocardial infarction	Enrichment	LTA	0.91
128	Malaria	Enrichment	TNF	0.90
129	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ZBTB16	0.90
130	Cakut	Enrichment	GATA3	0.74
131	Inherited cancer-predisposing syndrome	Enrichment	KIT, RUNX1	0.74
132	Gastric cancer	Enrichment	IL1B	0.65
133	Thrombocytopenia	Enrichment	RUNX1	0.61
134	Myeloma, multiple	Enrichment	IL7R	0.55
135	Primary ovarian insufficiency	Enrichment	NOTCH2	0.53
136	Cone-rod dystrophy 2	Enrichment	ITGA4	0.48
137	Ovarian cancer	Enrichment	KIT	0.35
138	Congenital nervous system abnormality	Enrichment	TPP1	0.33
139	Nervous system disease	Enrichment	TPP1	0.33
140	Retinitis pigmentosa	Enrichment	AHR	0.14
141	Hereditary retinal dystrophy	Enrichment	ITGA4	0.08
142	Fundus dystrophy	Enrichment	ITGA4	0.08

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Innate Lymphoid Cells Differentiation

Pathway Network for Innate Lymphoid Cells Differentiation

Member Pathways for Innate Lymphoid Cells Differentiation

Pathways in the Innate Lymphoid Cells Differentiation SuperPath

Associated Genes for Innate Lymphoid Cells Differentiation

Associated Disorders for Innate Lymphoid Cells Differentiation

Disorders associated with Innate Lymphoid Cells Differentiation SuperPath

STRING Interaction Network for Innate Lymphoid Cells Differentiation

Sources for Innate Lymphoid Cells Differentiation