Insulin-mediated glucose transport

No Pathway Network information available for Insulin-mediated glucose transport

Pathways in the Insulin-mediated glucose transport SuperPath

#	Name	Source	Genes
1	Insulin-mediated glucose transport	PubChem	AKT1 AKT2 ASIP GSK3B GYS1 INS INSR LNPEP PPP1CC PPP1R3A RHOQ SFN SLC2A4 STX4 STXBP4 TBC1D4 TRIP10 VAMP2 YKT6 (see all 19) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PPP1R3A	Protein Phosphatase 1 Regulatory Subunit 3A	Protein Coding	1
2	ASIP	Agouti Signaling Protein	Protein Coding	1
3	STXBP4	Syntaxin Binding Protein 4	Protein Coding	1
4	PPP1CC	Protein Phosphatase 1 Catalytic Subunit Gamma	Protein Coding	1
5	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
6	GYS1	Glycogen Synthase 1	Protein Coding	1
7	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	1
8	TBC1D4	TBC1 Domain Family Member 4	Protein Coding	1
9	RHOQ	Ras Homolog Family Member Q	Protein Coding	1
10	LNPEP	Leucyl And Cystinyl Aminopeptidase	Protein Coding	1
11	SFN	Stratifin	Protein Coding	1
12	TRIP10	Thyroid Hormone Receptor Interactor 10	Protein Coding	1
13	VAMP2	Vesicle Associated Membrane Protein 2	Protein Coding	1
14	STX4	Syntaxin 4	Protein Coding	1
15	YKT6	YKT6 Vesicular SNARE Protein	Protein Coding	1
16	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	1
17	INS	Insulin	Protein Coding	1
18	INSR	Insulin Receptor	Protein Coding	1
19	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	1

Disorders associated with Insulin-mediated glucose transport SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Type 2 diabetes mellitus	Enrichment	AKT2, INSR, PPP1R3A, SLC2A4, TBC1D4	8.60
2	Proteus syndrome	Enrichment	AKT1	2.85
3	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.85
4	Donohue syndrome	Enrichment	INSR	2.85
5	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	2.85
6	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	2.85
7	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	2.85
8	Type 2 diabetes 5	Enrichment	TBC1D4	2.85
9	Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements	Enrichment	VAMP2	2.85
10	Deafness, autosomal recessive 123	Enrichment	STX4	2.85
11	Cowden syndrome 6	Enrichment	AKT1	2.85
12	Skin/hair/eye pigmentation, variation in, 9	Enrichment	ASIP	2.85
13	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.85
14	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	2.55
15	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.55
16	Hyperproinsulinemia	Enrichment	INS	2.55
17	Glycogen storage disease 0, muscle	Enrichment	GYS1	2.55
18	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.55
19	Glycogen storage disease due to muscle and heart glycogen synthase deficiency	Enrichment	GYS1	2.55
20	Type 1 diabetes mellitus 2	Enrichment	INS	2.38
21	Neonatal diabetes mellitus	Enrichment	INS	2.25
22	Type 1 diabetes mellitus	Enrichment	INS	2.08
23	Breast adenocarcinoma	Enrichment	AKT1	2.08
24	46,xy disorder of sex development	Enrichment	INSR	2.08
25	Permanent neonatal diabetes mellitus	Enrichment	INS	1.95
26	Cowden syndrome	Enrichment	AKT1	1.90
27	Glycogen storage disease	Enrichment	GYS1	1.82
28	Diabetes mellitus	Enrichment	INS	1.82
29	Meningioma	Enrichment	AKT1	1.78
30	Maturity-onset diabetes of the young	Enrichment	INS	1.56
31	Hereditary breast carcinoma	Enrichment	AKT1	1.22
32	Sensorineural hearing loss	Enrichment	STX4	1.19
33	Breast cancer	Enrichment	AKT1	1.00
34	Colorectal cancer	Enrichment	AKT1	0.94
35	Ovarian cancer	Enrichment	AKT1	0.88

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Insulin-mediated glucose transport

Pathway Network for Insulin-mediated glucose transport

Member Pathways for Insulin-mediated glucose transport

Pathways in the Insulin-mediated glucose transport SuperPath

Associated Genes for Insulin-mediated glucose transport

Associated Disorders for Insulin-mediated glucose transport

Disorders associated with Insulin-mediated glucose transport SuperPath

STRING Interaction Network for Insulin-mediated glucose transport

Sources for Insulin-mediated glucose transport