Insulin processing

No Pathway Network information available for Insulin processing

Pathways in the Insulin processing SuperPath

#	Name	Source	Genes
1	Insulin processing	Reactome	CLTRN CPE ERO1B EXOC1 EXOC2 EXOC3 EXOC4 EXOC5 EXOC6 EXOC7 EXOC8 INS KIF5A KIF5B KIF5C MYO5A MYRIP P4HB PCSK1 PCSK2 RAB27A SLC30A5 SLC30A8 STX1A VAMP2 (see all 25) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	EXOC5	Exocyst Complex Component 5	Protein Coding	1
2	EXOC3	Exocyst Complex Component 3	Protein Coding	1
3	CPE	Carboxypeptidase E	Protein Coding	1
4	EXOC8	Exocyst Complex Component 8	Protein Coding	1
5	SLC30A8	Solute Carrier Family 30 Member 8	Protein Coding	1
6	EXOC7	Exocyst Complex Component 7	Protein Coding	1
7	MYRIP	Myosin VIIA And Rab Interacting Protein	Protein Coding	1
8	INS	Insulin	Protein Coding	1
9	KIF5A	Kinesin Family Member 5A	Protein Coding	1
10	KIF5B	Kinesin Family Member 5B	Protein Coding	1
11	KIF5C	Kinesin Family Member 5C	Protein Coding	1
12	MYO5A	Myosin VA	Protein Coding	1
13	P4HB	Prolyl 4-Hydroxylase Subunit Beta	Protein Coding	1
14	PCSK1	Proprotein Convertase Subtilisin/Kexin Type 1	Protein Coding	1
15	PCSK2	Proprotein Convertase Subtilisin/Kexin Type 2	Protein Coding	1
16	EXOC6	Exocyst Complex Component 6	Protein Coding	1
17	EXOC1	Exocyst Complex Component 1	Protein Coding	1
18	EXOC2	Exocyst Complex Component 2	Protein Coding	1
19	ERO1B	Endoplasmic Reticulum Oxidoreductase 1 Beta	Protein Coding	1
20	CLTRN	Collectrin, Amino Acid Transport Regulator	Protein Coding	1
21	RAB27A	RAB27A, Member RAS Oncogene Family	Protein Coding	1
22	EXOC4	Exocyst Complex Component 4	Protein Coding	1
23	SLC30A5	Solute Carrier Family 30 Member 5	Protein Coding	1
24	STX1A	Syntaxin 1A	Protein Coding	1
25	VAMP2	Vesicle Associated Membrane Protein 2	Protein Coding	1

Disorders associated with Insulin processing SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cole-carpenter syndrome 1	Enrichment	P4HB	2.73
2	Griscelli syndrome, type 2	Enrichment	RAB27A	2.73
3	Spastic paraplegia 10, autosomal dominant	Enrichment	KIF5A	2.73
4	Griscelli syndrome, type 1	Enrichment	MYO5A	2.73
5	Elejalde neuroectodermal melanolysosomal syndrome	Enrichment	MYO5A	2.73
6	Bdv syndrome	Enrichment	CPE	2.73
7	Myoclonus, intractable, neonatal	Enrichment	KIF5A	2.73
8	Amyotrophic lateral sclerosis 25	Enrichment	KIF5A	2.73
9	Neurodevelopmental disorder with hypotonia and autistic features with or without hyperkinetic movements	Enrichment	VAMP2	2.73
10	Cortical dysplasia, complex, with other brain malformations 2	Enrichment	KIF5C	2.73
11	Neurodevelopmental disorder with seizures and brain atrophy	Enrichment	EXOC7	2.73
12	Neurodevelopmental disorder with microcephaly, seizures, and brain atrophy	Enrichment	EXOC8	2.73
13	Griscelli syndrome	Enrichment	RAB27A	2.73
14	Cpe-related prader-willi-like syndrome	Enrichment	CPE	2.73
15	Autosomal dominant charcot-marie-tooth disease type 2 due to kif5a mutation	Enrichment	KIF5A	2.73
16	Hypertrophic cardiomyopathy	Enrichment	KIF5B, SLC30A5	2.55
17	Griscelli syndrome, type 3	Enrichment	MYO5A	2.43
18	Hartnup disorder	Enrichment	CLTRN	2.43
19	Maturity-onset diabetes of the young, type 10	Enrichment	INS	2.43
20	Hyperproinsulinemia	Enrichment	INS	2.43
21	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	KIF5A	2.43
22	Diabetes mellitus, permanent neonatal, 4	Enrichment	INS	2.43
23	Neurodevelopmental disorder with dysmorphic facies and cerebellar hypoplasia	Enrichment	EXOC2	2.43
24	Demyelinating polyneuropathy	Enrichment	KIF5A	2.43
25	Skeletal muscle disease	Enrichment	KIF5B	2.43
26	Type 1 diabetes mellitus 2	Enrichment	INS	2.26
27	Body mass index quantitative trait locus 12	Enrichment	PCSK1	2.26
28	Proprotein convertase 1/3 deficiency	Enrichment	PCSK1	2.26
29	Cole-carpenter syndrome	Enrichment	P4HB	2.26
30	Neonatal diabetes mellitus	Enrichment	INS	2.13
31	Kearns-sayre syndrome	Enrichment	KIF5B	2.04
32	2q23.1 microduplication syndrome	Enrichment	KIF5C	2.04
33	Osteogenesis imperfecta, type i	Enrichment	P4HB	1.96
34	Type 1 diabetes mellitus	Enrichment	INS	1.96
35	Permanent neonatal diabetes mellitus	Enrichment	INS	1.83
36	Hydrops fetalis	Enrichment	SLC30A5	1.78
37	Diabetes mellitus	Enrichment	INS	1.70
38	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	KIF5A	1.46
39	Williams-beuren syndrome	Enrichment	STX1A	1.44
40	Maturity-onset diabetes of the young	Enrichment	INS	1.44
41	Attention deficit-hyperactivity disorder	Enrichment	KIF5B	1.40
42	Multisystem inflammatory syndrome in children	Enrichment	RAB27A	1.40
43	Autoinflammatory disease	Enrichment	RAB27A	1.36
44	Auditory neuropathy	Enrichment	KIF5A	1.33
45	Meckel syndrome, type 1	Enrichment	EXOC4	1.28
46	Cystic fibrosis	Enrichment	STX1A	1.24
47	Peripheral nervous system disease	Enrichment	KIF5A	1.24
48	Neuropathy	Enrichment	KIF5A	1.24
49	Left ventricular noncompaction	Enrichment	SLC30A5	1.20
50	Dystonia	Enrichment	MYO5A	1.20
51	Type 2 diabetes mellitus	Enrichment	SLC30A8	1.13
52	Hereditary spastic paraplegia	Enrichment	KIF5A	1.13
53	Body mass index quantitative trait locus 11	Enrichment	PCSK1	1.05
54	Autism	Enrichment	STX1A	0.90
55	Dilated cardiomyopathy	Enrichment	KIF5B	0.86

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Insulin processing

Pathway Network for Insulin processing

Member Pathways for Insulin processing

Pathways in the Insulin processing SuperPath

Associated Genes for Insulin processing

Associated Disorders for Insulin processing

Disorders associated with Insulin processing SuperPath

STRING Interaction Network for Insulin processing

Sources for Insulin processing