Insulin signaling in adipocytes (diabetic condition)

Sources:

#	Name	Source	Genes
1	Insulin signaling in adipocytes (diabetic condition)	WikiPathways	AKT2 INSR IRS1 MTOR RPS6 RPS6KB1 SLC2A4 TBC1D4 (see all 8) (see less)
2	Insulin signaling in adipocytes (normal condition)	WikiPathways	AKT2 INSR IRS1 MTOR RPS6 RPS6KB1 SLC2A4 TBC1D4 (see all 8) (see less)
3	IL-4 signaling pathway	WikiPathways	RPS6KB1

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RPS6KB1	Ribosomal Protein S6 Kinase B1	Protein Coding	3
2	RPS6	Ribosomal Protein S6	Protein Coding	2
3	TBC1D4	TBC1 Domain Family Member 4	Protein Coding	2
4	SLC2A4	Solute Carrier Family 2 Member 4	Protein Coding	2
5	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	2
6	IRS1	Insulin Receptor Substrate 1	Protein Coding	2
7	INSR	Insulin Receptor	Protein Coding	2
8	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Type 2 diabetes mellitus	Enrichment	AKT2, INSR, IRS1, SLC2A4, TBC1D4	10.37
2	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	3.23
3	Donohue syndrome	Enrichment	INSR	3.23
4	Hyperinsulinemic hypoglycemia, familial, 5	Enrichment	INSR	3.23
5	Pineal hyperplasia, insulin-resistant diabetes mellitus, and somatic abnormalities	Enrichment	INSR	3.23
6	Diabetes mellitus, insulin-resistant, with acanthosis nigricans	Enrichment	INSR	3.23
7	Type 2 diabetes 5	Enrichment	TBC1D4	3.23
8	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	3.23
9	Hyperinsulinemic hypoglycemia, familial, 4	Enrichment	INSR	2.93
10	Cebalid syndrome	Enrichment	MTOR	2.93
11	Smith-kingsmore syndrome	Enrichment	MTOR	2.93
12	Focal cortical dysplasia, type ii	Enrichment	MTOR	2.63
13	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	2.63
14	Hemimegalencephaly	Enrichment	MTOR	2.53
15	46,xy disorder of sex development	Enrichment	INSR	2.45
16	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	2.38
17	Overgrowth syndrome	Enrichment	MTOR	2.38
18	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	2.05
19	Rare genetic intellectual disability	Enrichment	MTOR	2.05

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Insulin signaling in adipocytes (diabetic condition)