Interactions between LOXL4 and oxidative stress pathway

No Pathway Network information available for Interactions between LOXL4 and oxidative stress pathway

Pathways in the Interactions between LOXL4 and oxidative stress pathway SuperPath

#	Name	Source	Genes
1	Interactions between LOXL4 and oxidative stress pathway	WikiPathways	ANXA5 BMP2 CDC37 COL2A1 DDR1 ECSIT EXOC6 FGF7 FN1 IGFBP7 LOXL4 NFE2L2 NQO1 NRF1 PKD1 SIRT1 SUV39H1 TGFB1 (see all 18) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	LOXL4	Lysyl Oxidase Like 4	Protein Coding	1
2	DDR1	Discoidin Domain Receptor Tyrosine Kinase 1	Protein Coding	1
3	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
4	SUV39H1	SUV39H1 Histone Lysine Methyltransferase	Protein Coding	1
5	BMP2	Bone Morphogenetic Protein 2	Protein Coding	1
6	PKD1	Polycystin 1, Transient Receptor Potential Channel Interacting	Protein Coding	1
7	NRF1	Nuclear Respiratory Factor 1	Protein Coding	1
8	NFE2L2	NFE2 Like BZIP Transcription Factor 2	Protein Coding	1
9	IGFBP7	Insulin Like Growth Factor Binding Protein 7	Protein Coding	1
10	ANXA5	Annexin A5	Protein Coding	1
11	SIRT1	Sirtuin 1	Protein Coding	1
12	FN1	Fibronectin 1	Protein Coding	1
13	FGF7	Fibroblast Growth Factor 7	Protein Coding	1
14	NQO1	NAD(P)H Quinone Dehydrogenase 1	Protein Coding	1
15	COL2A1	Collagen Type II Alpha 1 Chain	Protein Coding	1
16	CDC37	Cell Division Cycle 37, HSP90 Cochaperone	Protein Coding	1
17	EXOC6	Exocyst Complex Component 6	Protein Coding	1
18	ECSIT	ECSIT Signaling Integrator	Protein Coding	1

Disorders associated with Interactions between LOXL4 and oxidative stress pathway SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	COL2A1, FN1	5.78
2	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	COL2A1, FN1	5.78
3	Stickler syndrome, type i	Enrichment	COL2A1	2.88
4	Epiphyseal dysplasia, multiple, with myopia and conductive deafness	Enrichment	COL2A1	2.88
5	Spondylometaphyseal dysplasia, algerian type	Enrichment	COL2A1	2.88
6	Osteoarthritis with mild chondrodysplasia	Enrichment	COL2A1	2.88
7	Avascular necrosis of femoral head, primary, 1	Enrichment	COL2A1	2.88
8	Czech dysplasia	Enrichment	COL2A1	2.88
9	Kniest dysplasia	Enrichment	COL2A1	2.88
10	Platyspondylic lethal skeletal dysplasia, torrance type	Enrichment	COL2A1	2.88
11	Spondyloepiphyseal dysplasia, stanescu type	Enrichment	COL2A1	2.88
12	Achondrogenesis, type ii	Enrichment	COL2A1	2.88
13	Immunodeficiency, developmental delay, and hypohomocysteinemia	Enrichment	NFE2L2	2.88
14	Spondyloperipheral dysplasia	Enrichment	COL2A1	2.88
15	Stickler syndrome, type i, nonsyndromic ocular	Enrichment	COL2A1	2.88
16	Retinal arterial macroaneurysm with supravalvular pulmonic stenosis	Enrichment	IGFBP7	2.88
17	20p12.3 microdeletion syndrome	Enrichment	BMP2	2.88
18	Short stature, facial dysmorphism, and skeletal anomalies with or without cardiac anomalies 1	Enrichment	BMP2	2.88
19	Vitreoretinopathy with phalangeal epiphyseal dysplasia	Enrichment	COL2A1	2.88
20	Autosomal dominant rhegmatogenous retinal detachment	Enrichment	COL2A1	2.88
21	Multiple epiphyseal dysplasia with myopia and deafness	Enrichment	COL2A1	2.88
22	Hypochondrogenesis	Enrichment	COL2A1	2.88
23	Renovascular hypertension	Enrichment	PKD1	2.88
24	Dysspondyloenchondromatosis	Enrichment	COL2A1	2.88
25	Type 2 collagen-related bone disorder	Enrichment	COL2A1	2.88
26	Camurati-engelmann disease 1	Enrichment	TGFB1	2.58
27	Otospondylomegaepiphyseal dysplasia, autosomal recessive	Enrichment	COL2A1	2.58
28	Legg-calve-perthes disease	Enrichment	COL2A1	2.58
29	Otospondylomegaepiphyseal dysplasia, autosomal dominant	Enrichment	COL2A1	2.58
30	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	2.58
31	Camurati-engelmann disease	Enrichment	TGFB1	2.58
32	Familial avascular necrosis of the femoral head	Enrichment	COL2A1	2.58
33	Craniosynostosis 7	Enrichment	BMP2	2.58
34	Polycystic kidney disease 3	Enrichment	PKD1	2.58
35	Mccune-albright syndrome	Enrichment	COL2A1	2.40
36	Spondyloepiphyseal dysplasia congenita	Enrichment	COL2A1	2.40
37	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	PKD1	2.40
38	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.40
39	Transposition of the great arteries, dextro-looped	Enrichment	BMP2	2.40
40	Tuberous sclerosis 2	Enrichment	PKD1	2.40
41	End stage renal disease	Enrichment	PKD1	2.40
42	Multiple epiphyseal dysplasia	Enrichment	COL2A1	2.40
43	Brachydactyly, type a2	Enrichment	BMP2	2.28
44	Pregnancy loss, recurrent 3	Enrichment	ANXA5	2.28
45	Tuberous sclerosis	Enrichment	PKD1	2.28
46	Polycystic liver disease 1 with or without kidney cysts	Enrichment	PKD1	2.18
47	Retinal detachment	Enrichment	COL2A1	2.18
48	Polycystic kidney disease 3 with or without polycystic liver disease	Enrichment	PKD1	2.18
49	Ventricular septal defect 1	Enrichment	BMP2	2.18
50	Polycystic liver disease 1	Enrichment	PKD1	2.18
51	Hemangioma	Enrichment	PKD1	2.18
52	Atrial septal defect 1	Enrichment	BMP2	2.10
53	Developmental dysplasia of the hip 1	Enrichment	COL2A1	2.10
54	Renal dysplasia, cystic	Enrichment	PKD1	2.10
55	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	2.10
56	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	2.10
57	Multicystic kidney dysplasia	Enrichment	PKD1	2.10
58	Multicystic dysplastic kidney	Enrichment	PKD1	2.10
59	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	PKD1	2.03
60	Multiple enchondromatosis, maffucci type	Enrichment	COL2A1	2.03
61	Polycystic kidney disease 1	Enrichment	PKD1	2.03
62	Hemochromatosis, type 1	Enrichment	BMP2	1.98
63	Polycystic kidney disease 4 with or without polycystic liver disease	Enrichment	PKD1	1.98
64	Cystic kidney disease	Enrichment	PKD1	1.93
65	Marfan syndrome	Enrichment	COL2A1	1.88
66	Stickler syndrome	Enrichment	COL2A1	1.88
67	Myopia	Enrichment	COL2A1	1.70
68	Autosomal dominant polycystic kidney disease	Enrichment	PKD1	1.70
69	Kidney disease	Enrichment	PKD1	1.70
70	Creatine phosphokinase, elevated serum	Enrichment	PKD1	1.68
71	Hypertension	Enrichment	PKD1	1.68
72	Isolated elevated serum creatine phosphokinase levels	Enrichment	PKD1	1.68
73	Heart, malformation of	Enrichment	COL2A1	1.63
74	Polycystic kidney disease	Enrichment	PKD1	1.63
75	Scoliosis	Enrichment	COL2A1	1.50
76	Stargardt disease 1	Enrichment	COL2A1	1.41
77	Lung cancer	Enrichment	NFE2L2	1.38
78	Cystic fibrosis	Enrichment	TGFB1	1.38
79	Connective tissue disease	Enrichment	COL2A1	1.38
80	Nephrotic syndrome	Enrichment	FN1	1.26
81	Colorectal cancer	Enrichment	NFE2L2	0.96
82	Inherited cancer-predisposing syndrome	Enrichment	PKD1	0.79
83	Hereditary retinal dystrophy	Enrichment	COL2A1	0.49
84	Fundus dystrophy	Enrichment	COL2A1	0.49

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Interactions between LOXL4 and oxidative stress pathway

Pathway Network for Interactions between LOXL4 and oxidative stress pathway

Member Pathways for Interactions between LOXL4 and oxidative stress pathway

Pathways in the Interactions between LOXL4 and oxidative stress pathway SuperPath

Associated Genes for Interactions between LOXL4 and oxidative stress pathway

Associated Disorders for Interactions between LOXL4 and oxidative stress pathway

Disorders associated with Interactions between LOXL4 and oxidative stress pathway SuperPath

STRING Interaction Network for Interactions between LOXL4 and oxidative stress pathway

Sources for Interactions between LOXL4 and oxidative stress pathway