Interactome of polycomb repressive complex 2 (PRC2)

No Pathway Network information available for Interactome of polycomb repressive complex 2 (PRC2)

#	Name	Source	Genes
1	Interactome of polycomb repressive complex 2 (PRC2)	WikiPathways	AEBP2 BCLAF1 EED ELL EZH1 EZH2 JARID2 MORC3 MTF2 RBBP4 RBBP7 SETX STK38 SUZ12 THRAP3 TRIM35 (see all 16) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BCLAF1	BCL2 Associated Transcription Factor 1	Protein Coding	1
2	EED	Embryonic Ectoderm Development	Protein Coding	1
3	JARID2	Jumonji And AT-Rich Interaction Domain Containing 2	Protein Coding	1
4	SUZ12	SUZ12 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
5	SETX	Senataxin	Protein Coding	1
6	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
7	THRAP3	Thyroid Hormone Receptor Associated Protein 3	Protein Coding	1
8	AEBP2	AE Binding Protein 2	Protein Coding	1
9	STK38	Serine/Threonine Kinase 38	Protein Coding	1
10	ELL	Elongation Factor For RNA Polymerase II	Protein Coding	1
11	RBBP7	RB Binding Protein 7, Chromatin Remodeling Factor	Protein Coding	1
12	RBBP4	RB Binding Protein 4, Chromatin Remodeling Factor	Protein Coding	1
13	MORC3	MORC Family CW-Type Zinc Finger 3	Protein Coding	1
14	TRIM35	Tripartite Motif Containing 35	Protein Coding	1
15	MTF2	Metal Response Element Binding Transcription Factor 2	Protein Coding	1
16	EZH1	Enhancer Of Zeste 1 Polycomb Repressive Complex 2 Subunit	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Weaver syndrome	Enrichment	EZH2, SUZ12	5.41
2	Amyotrophic lateral sclerosis 4, juvenile	Enrichment	SETX	2.93
3	Spermatogenic failure, x-linked, 9	Enrichment	RBBP7	2.93
4	Imagawa-matsumoto syndrome	Enrichment	SUZ12	2.93
5	Developmental delay with variable intellectual disability and dysmorphic facies	Enrichment	JARID2	2.93
6	Cohen-gibson syndrome	Enrichment	EED	2.93
7	Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2	Enrichment	SETX	2.63
8	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	SETX	2.33
9	Endometrial stromal sarcoma	Enrichment	SUZ12	2.23
10	Stereotypic movement disorder	Enrichment	JARID2	1.82
11	Cerebral palsy	Enrichment	SETX	1.35
12	Autosomal dominant non-syndromic intellectual disability	Enrichment	JARID2	1.24
13	Spastic ataxia	Enrichment	SETX	1.22
14	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	SETX	1.18
15	Autism	Enrichment	JARID2	1.09
16	Autism spectrum disorder	Enrichment	EED	0.92
17	Complex neurodevelopmental disorder	Enrichment	JARID2	0.86
18	Inherited cancer-predisposing syndrome	Enrichment	EZH2	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Interactome of polycomb repressive complex 2 (PRC2)