Iron metabolism in placenta

No Pathway Network information available for Iron metabolism in placenta

#	Name	Source	Genes
1	Iron metabolism in placenta	WikiPathways	ACO1 HEPHL1 IREB2 MCOLN1 SLC11A2 SLC40A1 STEAP3 TFR2 (see all 8) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TFR2	Transferrin Receptor 2	Protein Coding	1
2	MCOLN1	Mucolipin TRP Cation Channel 1	Protein Coding	1
3	STEAP3	STEAP3 Metalloreductase	Protein Coding	1
4	SLC11A2	Solute Carrier Family 11 Member 2	Protein Coding	1
5	ACO1	Aconitase 1	Protein Coding	1
6	IREB2	Iron Responsive Element Binding Protein 2	Protein Coding	1
7	SLC40A1	Solute Carrier Family 40 Member 1	Protein Coding	1
8	HEPHL1	Hephaestin Like 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Abnormal hair, joint laxity, and developmental delay	Enrichment	HEPHL1	3.23
2	Anemia, hypochromic microcytic, with iron overload 1	Enrichment	SLC11A2	3.23
3	Hemochromatosis, type 4	Enrichment	SLC40A1	3.23
4	Neurodegeneration, early-onset, with choreoathetoid movements and microcytic anemia	Enrichment	IREB2	3.23
5	Anemia, hypochromic microcytic, with iron overload 2	Enrichment	STEAP3	2.93
6	Mucolipidosis iv	Enrichment	MCOLN1	2.93
7	Corneal dystrophy, lisch epithelial	Enrichment	MCOLN1	2.93
8	Hemochromatosis, type 3	Enrichment	TFR2	2.75
9	Mucolipidosis	Enrichment	MCOLN1	2.75
10	Periventricular leukomalacia	Enrichment	MCOLN1	2.75
11	Digenic hemochromatosis	Enrichment	TFR2	2.63
12	Hemochromatosis, type 1	Enrichment	TFR2	2.33
13	Congenital nervous system abnormality	Enrichment	MCOLN1	1.22
14	Nervous system disease	Enrichment	MCOLN1	1.22

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Iron metabolism in placenta