L-dopa and L-dopachrome biosynthesis

Sources:

#	Name	Source	Genes
1	L-dopa and L-dopachrome biosynthesis	PubChem	TYR
2	(S)-reticuline biosynthesis	PubChem	TYR
3	eumelanin biosynthesis	PubChem	TYR
4	pheomelanin biosynthesis	PubChem	TYR
5	(S)-reticuline biosynthesis II	PubChem	TYR
6	L-dopachrome biosynthesis	PubChem	TYR

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	TYR	Tyrosinase	Protein Coding	6

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Albinism, oculocutaneous, type ib	Enrichment	TYR	4.13
2	Skin/hair/eye pigmentation, variation in, 3	Enrichment	TYR	4.13
3	Minimal pigment oculocutaneous albinism type 1	Enrichment	TYR	4.13
4	Hypopigmentation of the skin	Enrichment	TYR	4.13
5	Albinism, oculocutaneous, type ia	Enrichment	TYR	3.83
6	Melanoma, cutaneous malignant 8	Enrichment	TYR	3.83
7	Albinism, ocular, type i	Enrichment	TYR	3.35
8	Albinism	Enrichment	TYR	3.35
9	Waardenburg syndrome, type 2e	Enrichment	TYR	3.29
10	Oculocutaneous albinism	Enrichment	TYR	3.29
11	Optic nerve disease	Enrichment	TYR	3.13
12	Myopia	Enrichment	TYR	2.96
13	Skin disease	Enrichment	TYR	2.79
14	Strabismus	Enrichment	TYR	2.70
15	Eye disease	Enrichment	TYR	2.59

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for L-dopa and L-dopachrome biosynthesis