L-phenylalanine degradation I (aerobic)

No Pathway Network information available for L-phenylalanine degradation I (aerobic)

#	Name	Source	Genes
1	L-phenylalanine degradation I (aerobic)	PubChem	PAH PCBD1 PCBD2 QDPR
2	phenylalanine degradation/tyrosine biosynthesis	PubChem	PAH PCBD1 PCBD2 QDPR

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	PCBD2	Pterin-4 Alpha-Carbinolamine Dehydratase 2	Protein Coding	2
2	PCBD1	Pterin-4 Alpha-Carbinolamine Dehydratase 1	Protein Coding	2
3	PAH	Phenylalanine Hydroxylase	Protein Coding	2
4	QDPR	Quinoid Dihydropteridine Reductase	Protein Coding	2

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hyperphenylalaninemia, bh4-deficient, a	Enrichment	PAH, QDPR	6.01
2	Tetrahydrobiopterin-responsive hyperphenylalaninemia/phenylketonuria	Enrichment	PAH	3.53
3	Hyperphenylalaninemia, bh4-deficient, c	Enrichment	QDPR	3.23
4	Hyperphenylalaninemia, bh4-deficient, d	Enrichment	PCBD1	3.23
5	Neurodevelopmental disorder with spasticity, hypomyelinating leukodystrophy, and brain abnormalities	Enrichment	PAH	3.23
6	Pituitary hormone deficiency, combined, 2	Enrichment	PAH	3.05
7	Hyperphenylalaninemia due to tetrahydrobiopterin deficiency	Enrichment	QDPR	3.05
8	Phenylketonuria	Enrichment	PAH	2.93
9	Propionic acidemia	Enrichment	PAH	2.93
10	Pulmonary hypertension, primary, 1	Enrichment	PAH	2.42
11	Rasopathy	Enrichment	PAH	2.12
12	Breast cancer	Enrichment	PAH	1.66

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for L-phenylalanine degradation I (aerobic)