Lactate shuttle in glial cells

No Pathway Network information available for Lactate shuttle in glial cells

Pathways in the Lactate shuttle in glial cells SuperPath

#	Name	Source	Genes
1	Lactate shuttle in glial cells	WikiPathways	CA2 CA4 HK1 LDHA NUDT14 SLC16A1 SLC16A3 SLC16A7 SLC1A2 SLC2A1 SLC2A3 SLC4A4 (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SLC1A2	Solute Carrier Family 1 Member 2	Protein Coding	1
2	NUDT14	Nudix Hydrolase 14	Protein Coding	1
3	HK1	Hexokinase 1	Protein Coding	1
4	CA4	Carbonic Anhydrase 4	Protein Coding	1
5	CA2	Carbonic Anhydrase 2	Protein Coding	1
6	SLC16A3	Solute Carrier Family 16 Member 3	Protein Coding	1
7	SLC16A1	Solute Carrier Family 16 Member 1	Protein Coding	1
8	SLC16A7	Solute Carrier Family 16 Member 7	Protein Coding	1
9	SLC2A3	Solute Carrier Family 2 Member 3	Protein Coding	1
10	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
11	SLC4A4	Solute Carrier Family 4 Member 4	Protein Coding	1
12	LDHA	Lactate Dehydrogenase A	Protein Coding	1

Disorders associated with Lactate shuttle in glial cells SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Anemia, congenital, nonspherocytic hemolytic, 5	Enrichment	HK1	3.05
2	Retinitis pigmentosa 17	Enrichment	CA4	3.05
3	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	3.05
4	Erythrocyte lactate transporter defect	Enrichment	SLC16A1	3.05
5	Developmental and epileptic encephalopathy 41	Enrichment	SLC1A2	3.05
6	Retinitis pigmentosa 79	Enrichment	HK1	3.05
7	Neuropathy, hereditary motor and sensory, russe type	Enrichment	HK1	3.05
8	Neurodevelopmental disorder with visual defects and brain anomalies	Enrichment	HK1	3.05
9	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	3.05
10	Epilepsy with myoclonic absences	Enrichment	SLC2A1	3.05
11	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	3.05
12	Fanconi-bickel syndrome	Enrichment	LDHA	2.75
13	Dystonia 9	Enrichment	SLC2A1	2.75
14	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.75
15	Proximal renal tubular acidosis-ocular anomaly syndrome	Enrichment	SLC4A4	2.75
16	Monocarboxylate transporter 1 deficiency	Enrichment	SLC16A1	2.75
17	Osteopetrosis, autosomal recessive 3	Enrichment	CA2	2.75
18	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.75
19	Hyperinsulinemic hypoglycemia, familial, 7	Enrichment	SLC16A1	2.75
20	Autosomal recessive proximal renal tubular acidosis	Enrichment	SLC4A4	2.75
21	Ketoacidosis due to monocarboxylate transporter-1 deficiency	Enrichment	SLC16A1	2.75
22	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.58
23	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.58
24	Huntington disease	Enrichment	SLC2A3	2.45
25	Osteopetrosis	Enrichment	CA2	2.35
26	Paroxysmal dystonia	Enrichment	SLC2A1	2.21
27	Alternating hemiplegia of childhood	Enrichment	SLC2A1	2.15
28	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	2.10
29	Retinitis pigmentosa	Enrichment	CA4, HK1	1.84
30	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.66
31	Strabismus	Enrichment	SLC2A1	1.63
32	Hereditary retinal dystrophy	Enrichment	CA4, HK1	1.58
33	Fundus dystrophy	Enrichment	CA4, HK1	1.58
34	Epilepsy	Enrichment	SLC2A1	1.46
35	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.45
36	Centralopathic epilepsy	Enrichment	SLC2A1	1.43
37	West syndrome	Enrichment	SLC2A1	1.42
38	Undetermined early-onset epileptic encephalopathy	Enrichment	SLC1A2	1.31
39	Autism spectrum disorder	Enrichment	HK1	1.03
40	Microcephaly	Enrichment	SLC2A1	0.98

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Lactate shuttle in glial cells

Pathway Network for Lactate shuttle in glial cells

Member Pathways for Lactate shuttle in glial cells

Pathways in the Lactate shuttle in glial cells SuperPath

Associated Genes for Lactate shuttle in glial cells

Associated Disorders for Lactate shuttle in glial cells

Disorders associated with Lactate shuttle in glial cells SuperPath

STRING Interaction Network for Lactate shuttle in glial cells

Sources for Lactate shuttle in glial cells