Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics

No Pathway Network information available for Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics

#	Name	Source	Genes
1	Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics	PharmGKB	ABCB1 ABCC1 ABCC2 ABCC3 ABCC4 ABCG2 CHPT1 CMPK1 DCK NME1 NME2 NT5C PCYT1A PCYT2 PGK1 SLC22A1 SLC22A2 SLC22A3 (see all 18) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CHPT1	Choline Phosphotransferase 1	Protein Coding	1
2	PCYT2	Phosphate Cytidylyltransferase 2, Ethanolamine	Protein Coding	1
3	NT5C	5'', 3''-Nucleotidase, Cytosolic	Protein Coding	1
4	SLC22A1	Solute Carrier Family 22 Member 1	Protein Coding	1
5	SLC22A3	Solute Carrier Family 22 Member 3	Protein Coding	1
6	SLC22A2	Solute Carrier Family 22 Member 2	Protein Coding	1
7	ABCC4	ATP Binding Cassette Subfamily C Member 4 (PEL Blood Group)	Protein Coding	1
8	ABCC3	ATP Binding Cassette Subfamily C Member 3	Protein Coding	1
9	PCYT1A	Phosphate Cytidylyltransferase 1A, Choline	Protein Coding	1
10	NME1	NME/NM23 Nucleoside Diphosphate Kinase 1	Protein Coding	1
11	NME2	NME/NM23 Nucleoside Diphosphate Kinase 2	Protein Coding	1
12	DCK	Deoxycytidine Kinase	Protein Coding	1
13	ABCC1	ATP Binding Cassette Subfamily C Member 1 (ABCC1 Blood Group)	Protein Coding	1
14	ABCB1	ATP Binding Cassette Subfamily B Member 1	Protein Coding	1
15	PGK1	Phosphoglycerate Kinase 1	Protein Coding	1
16	ABCC2	ATP Binding Cassette Subfamily C Member 2	Protein Coding	1
17	ABCG2	ATP Binding Cassette Subfamily G Member 2 (JR Blood Group)	Protein Coding	1
18	CMPK1	Cytidine/Uridine Monophosphate Kinase 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Phosphoglycerate kinase 1 deficiency	Enrichment	PGK1	2.88
2	Colchicine resistance	Enrichment	ABCB1	2.88
3	Uric acid concentration, serum, quantitative trait locus 1	Enrichment	ABCG2	2.88
4	Encephalopathy, acute transient	Enrichment	ABCB1	2.88
5	Deafness, autosomal dominant 77	Enrichment	ABCC1	2.88
6	Inflammatory bowel disease 13	Enrichment	ABCB1	2.88
7	Blood group, junior system	Enrichment	ABCG2	2.88
8	Male infertility due to obstructive azoospermia	Enrichment	PGK1	2.88
9	Spondylometaphyseal dysplasia with cone-rod dystrophy	Enrichment	PCYT1A	2.58
10	Spastic paraplegia 82, autosomal recessive	Enrichment	PCYT2	2.58
11	Lipodystrophy, congenital generalized, type 5	Enrichment	PCYT1A	2.58
12	Dubin-johnson syndrome	Enrichment	ABCC2	2.40
13	Pseudoxanthoma elasticum	Enrichment	ABCC2	2.10
14	Epilepsy, idiopathic generalized	Enrichment	ABCB1	1.84
15	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	ABCC1	1.17
16	Leber plus disease	Enrichment	PCYT1A	0.92

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Lamivudine Pathway, Pharmacokinetics/Pharmacodynamics