LDL Oxidation in Atherogenesis

No Pathway Network information available for LDL Oxidation in Atherogenesis

#	Name	Source	Genes
1	LDL Oxidation in Atherogenesis	QIAGEN	CCL2 CCL3 CD36 CD68 CSF1 ICAM1 IL1B MPO MSR1 PLA2G4A PLA2G4C SMPD1 SMPD2 SMPD3 TNF VCAM1 (see all 16) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CCL2	C-C Motif Chemokine Ligand 2	Protein Coding	1
2	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	1
3	CD36	CD36 Molecule (CD36 Blood Group)	Protein Coding	1
4	CD68	CD68 Molecule	Protein Coding	1
5	CSF1	Colony Stimulating Factor 1	Protein Coding	1
6	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
7	IL1B	Interleukin 1 Beta	Protein Coding	1
8	MPO	Myeloperoxidase	Protein Coding	1
9	MSR1	Macrophage Scavenger Receptor 1	Protein Coding	1
10	PLA2G4A	Phospholipase A2 Group IVA	Protein Coding	1
11	PLA2G4C	Phospholipase A2 Group IVC	Protein Coding	1
12	SMPD1	Sphingomyelin Phosphodiesterase 1	Protein Coding	1
13	SMPD2	Sphingomyelin Phosphodiesterase 2	Protein Coding	1
14	SMPD3	Sphingomyelin Phosphodiesterase 3	Protein Coding	1
15	TNF	Tumor Necrosis Factor	Protein Coding	1
16	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Cerebral malaria	Enrichment	CD36, ICAM1, TNF	8.27
2	Malaria	Enrichment	CD36, ICAM1, TNF	5.63
3	Alzheimer's disease	Enrichment	MPO, TNF	4.00
4	Human immunodeficiency virus type 1	Enrichment	CCL2, CCL3	3.70
5	Coronary heart disease 7	Enrichment	CD36	2.93
6	Platelet glycoprotein iv deficiency	Enrichment	CD36	2.93
7	Cytosolic phospholipase-a2 alpha deficiency associated bleeding disorder	Enrichment	PLA2G4A	2.93
8	Acid sphingomyelinase deficiency	Enrichment	SMPD1	2.93
9	Gastrointestinal ulceration, recurrent, with dysfunctional platelets	Enrichment	PLA2G4A	2.93
10	Cryptogenic multifocal ulcerous stenosing enteritis	Enrichment	PLA2G4A	2.93
11	Immunodeficiency 127	Enrichment	TNF	2.63
12	Niemann-pick disease, type a	Enrichment	SMPD1	2.45
13	Psoriatic arthritis	Enrichment	TNF	2.45
14	Niemann-pick disease, type b	Enrichment	SMPD1	2.45
15	Ceroid lipofuscinosis, neuronal, 6a	Enrichment	SMPD1	2.45
16	Migraine without aura	Enrichment	TNF	2.45
17	Myeloperoxidase deficiency	Enrichment	MPO	2.33
18	Barrett esophagus	Enrichment	MSR1	2.33
19	Blood platelet disease	Enrichment	CD36	2.33
20	Niemann-pick disease, type c1	Enrichment	SMPD1	2.23
21	Niemann-pick disease	Enrichment	SMPD1	2.23
22	Vascular dementia	Enrichment	TNF	2.23
23	Alzheimer's disease 1	Enrichment	MPO	2.08
24	Asthma	Enrichment	TNF	1.89
25	Alzheimer disease, familial, 1	Enrichment	MPO	1.70
26	Prostate cancer	Enrichment	MSR1	1.47
27	Systemic lupus erythematosus	Enrichment	TNF	1.35
28	Gastric cancer	Enrichment	IL1B	1.30
29	Ovarian cancer	Enrichment	MSR1	0.95

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for LDL Oxidation in Atherogenesis