Leukocyte-intrinsic Hippo pathway functions

No Pathway Network information available for Leukocyte-intrinsic Hippo pathway functions

Pathways in the Leukocyte-intrinsic Hippo pathway functions SuperPath

#	Name	Source	Genes
1	Leukocyte-intrinsic Hippo pathway functions	WikiPathways	CD19 FERMT3 FOXO1 FOXO3 FOXO4 FOXO6 FOXP3 FYB1 ITGAL KNSTRN LATS1 LATS2 LPL MAPK14 MIR21 MOB1A MST1 NDRG1 PRDM1 RAC1 RAP1A RASSF5 SAV1 STK3 STK38L TAFAZZIN TEAD1 TEAD2 TEAD3 TEAD4 YAP1 YWHAQ (see all 32) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RAP1A	RAP1A, Member Of RAS Oncogene Family	Protein Coding	1
2	CD19	CD19 Molecule	Protein Coding	1
3	LATS1	Large Tumor Suppressor Kinase 1	Protein Coding	1
4	KNSTRN	Kinetochore Localized Astrin (SPAG5) Binding Protein	Protein Coding	1
5	TEAD2	TEA Domain Transcription Factor 2	Protein Coding	1
6	FERMT3	FERM Domain Containing Kindlin 3	Protein Coding	1
7	RASSF5	Ras Association Domain Family Member 5	Protein Coding	1
8	TEAD1	TEA Domain Transcription Factor 1	Protein Coding	1
9	TAFAZZIN	Tafazzin, Phospholipid-Lysophospholipid Transacylase	Protein Coding	1
10	PRDM1	PR/SET Domain 1	Protein Coding	1
11	RAC1	Rac Family Small GTPase 1	Protein Coding	1
12	FOXP3	Forkhead Box P3~Name Same As:- HGNC:13781	Protein Coding	1
13	MST1	Macrophage Stimulating 1	Protein Coding	1
14	MIR21	MicroRNA 21	RNA Gene	1
15	LPL	Lipoprotein Lipase	Protein Coding	1
16	ITGAL	Integrin Subunit Alpha L	Protein Coding	1
17	LATS2	Large Tumor Suppressor Kinase 2	Protein Coding	1
18	FYB1	FYN Binding Protein 1	Protein Coding	1
19	FOXO3	Forkhead Box O3	Protein Coding	1
20	FOXO1	Forkhead Box O1	Protein Coding	1
21	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
22	YWHAQ	Tyrosine 3-Monooxygenase/Tryptophan 5-Monooxygenase Activation Protein Theta	Protein Coding	1
23	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
24	NDRG1	N-Myc Downstream Regulated 1	Protein Coding	1
25	TEAD3	TEA Domain Transcription Factor 3	Protein Coding	1
26	TEAD4	TEA Domain Transcription Factor 4	Protein Coding	1
27	STK3	Serine/Threonine Kinase 3	Protein Coding	1
28	SAV1	Salvador Family WW Domain Containing Protein 1	Protein Coding	1
29	MOB1A	MOB Kinase Activator 1A	Protein Coding	1
30	FOXO4	Forkhead Box O4	Protein Coding	1
31	STK38L	Serine/Threonine Kinase 38 Like	Protein Coding	1
32	FOXO6	Forkhead Box O6	Protein Coding	1

Disorders associated with Leukocyte-intrinsic Hippo pathway functions SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Malignant peritoneal mesothelioma	Enrichment	LATS1, LATS2	5.27
2	Immunodysregulation, polyendocrinopathy, and enteropathy, x-linked	Enrichment	FOXP3	2.63
3	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	2.63
4	Thrombocytopenia 3	Enrichment	FYB1	2.63
5	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	2.63
6	Immunodeficiency, common variable, 3	Enrichment	CD19	2.63
7	Congenital autosomal recessive small-platelet thrombocytopenia	Enrichment	FYB1	2.63
8	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.63
9	Leukocyte adhesion deficiency, type i	Enrichment	FERMT3	2.33
10	Sveinsson chorioretinal atrophy	Enrichment	TEAD1	2.33
11	Multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly	Enrichment	FOXP3	2.33
12	Hyperlipoproteinemia, type i	Enrichment	LPL	2.33
13	Leukocyte adhesion deficiency, type iii	Enrichment	FERMT3	2.33
14	Roifman-chitayat syndrome	Enrichment	KNSTRN	2.33
15	Lipase deficiency, combined	Enrichment	LPL	2.33
16	Charcot-marie-tooth disease, demyelinating, type 4d	Enrichment	NDRG1	2.33
17	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.33
18	Retinitis pigmentosa 14	Enrichment	TEAD3	2.33
19	Familial lipoprotein lipase deficiency	Enrichment	LPL	2.33
20	Charcot-marie-tooth disease type 4d	Enrichment	NDRG1	2.33
21	Common variable immunodeficiency phenotype due to cd19/cd81 deficiency	Enrichment	CD19	2.33
22	Barth syndrome	Enrichment	TAFAZZIN	2.15
23	Myeloma, multiple	Enrichment	LATS1, YAP1	2.12
24	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	2.03
25	Coronary artery anomaly	Enrichment	LPL	2.03
26	Hyperlipidemia, familial combined, 3	Enrichment	LPL	1.93
27	Rhabdomyosarcoma 2	Enrichment	FOXO1	1.93
28	Cholangitis, primary sclerosing	Enrichment	MST1	1.93
29	Type 1 diabetes mellitus	Enrichment	FOXP3	1.85
30	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.68
31	Hydrops fetalis	Enrichment	FOXP3	1.68
32	Microphthalmia/coloboma 12	Enrichment	YAP1	1.52
33	Coloboma of macula	Enrichment	YAP1	1.46
34	Charcot-marie-tooth disease type 4	Enrichment	NDRG1	1.38
35	Diffuse large b-cell lymphoma	Enrichment	FOXO1	1.36
36	Cardiomyopathy, dilated, 1a	Enrichment	LPL	1.31
37	Centronuclear myopathy	Enrichment	FOXP3	1.31
38	Left ventricular noncompaction	Enrichment	TAFAZZIN	1.10
39	Charcot-marie-tooth disease	Enrichment	NDRG1	1.03
40	Familial isolated dilated cardiomyopathy	Enrichment	TAFAZZIN	0.93
41	Dilated cardiomyopathy	Enrichment	TAFAZZIN	0.76
42	Leber plus disease	Enrichment	TEAD3	0.70
43	Hereditary retinal dystrophy	Enrichment	TEAD3	0.30
44	Fundus dystrophy	Enrichment	TEAD3	0.30

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Leukocyte-intrinsic Hippo pathway functions

Pathway Network for Leukocyte-intrinsic Hippo pathway functions

Member Pathways for Leukocyte-intrinsic Hippo pathway functions

Pathways in the Leukocyte-intrinsic Hippo pathway functions SuperPath

Associated Genes for Leukocyte-intrinsic Hippo pathway functions

Associated Disorders for Leukocyte-intrinsic Hippo pathway functions

Disorders associated with Leukocyte-intrinsic Hippo pathway functions SuperPath

STRING Interaction Network for Leukocyte-intrinsic Hippo pathway functions

Sources for Leukocyte-intrinsic Hippo pathway functions