Lysosphingolipid and LPA receptors
Pathways in the Lysosphingolipid and LPA receptors SuperPath
| # | Name | Source | Genes |
|---|---|---|---|
| 1 | Lysosphingolipid and LPA receptors | Reactome |
Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways
| # | Symbol | Description | Category | # Related Pathways |
|---|---|---|---|---|
| 1 | PLPPR5 | Phospholipid Phosphatase Related 5 | Protein Coding | 1 |
| 2 | S1PR1 | Sphingosine-1-Phosphate Receptor 1 | Protein Coding | 1 |
| 3 | LPAR1 | Lysophosphatidic Acid Receptor 1 | Protein Coding | 1 |
| 4 | S1PR3 | Sphingosine-1-Phosphate Receptor 3 | Protein Coding | 1 |
| 5 | LPAR3 | Lysophosphatidic Acid Receptor 3 | Protein Coding | 1 |
| 6 | S1PR5 | Sphingosine-1-Phosphate Receptor 5 | Protein Coding | 1 |
| 7 | PLPPR1 | Phospholipid Phosphatase Related 1 | Protein Coding | 1 |
| 8 | LPAR5 | Lysophosphatidic Acid Receptor 5 | Protein Coding | 1 |
| 9 | PLPPR2 | Phospholipid Phosphatase Related 2 | Protein Coding | 1 |
| 10 | PLPPR3 | Phospholipid Phosphatase Related 3 | Protein Coding | 1 |
| 11 | S1PR4 | Sphingosine-1-Phosphate Receptor 4 | Protein Coding | 1 |
| 12 | LPAR2 | Lysophosphatidic Acid Receptor 2 | Protein Coding | 1 |
| 13 | S1PR2 | Sphingosine-1-Phosphate Receptor 2 | Protein Coding | 1 |
| 14 | PLPPR4 | Phospholipid Phosphatase Related 4 | Protein Coding | 1 |
Disorders associated with Lysosphingolipid and LPA receptors SuperPath
according to GeneCards Suite gene sharing
| # | Disorder | Type | Genes | Score |
|---|---|---|---|---|
| 1 | Deafness, autosomal recessive 68 | Enrichment | S1PR2 | 2.99 |
| 2 | Rare autosomal recessive non-syndromic sensorineural deafness type dfnb | Enrichment | S1PR2 | 1.06 |
