Macrophage Differentiation and Growth Inhibition by METS

No Pathway Network information available for Macrophage Differentiation and Growth Inhibition by METS

Pathways in the Macrophage Differentiation and Growth Inhibition by METS SuperPath

#	Name	Source	Genes
1	Macrophage Differentiation and Growth Inhibition by METS	QIAGEN	CSF1 CSF1R DDX20 E2F4 ETS1 ETS2 ETV3 FOS HDAC1 HDAC10 HDAC11 HDAC2 HDAC3 HDAC5 HDAC6 HDAC7 HDAC8 HDAC9 HRAS JUN NCOR1 NCOR2 RB1 RBL1 RBL2 SIN3A SIN3B (see all 27) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CSF1	Colony Stimulating Factor 1	Protein Coding	1
2	CSF1R	Colony Stimulating Factor 1 Receptor	Protein Coding	1
3	DDX20	DEAD-Box Helicase 20	Protein Coding	1
4	E2F4	E2F Transcription Factor 4	Protein Coding	1
5	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
6	ETS2	ETS Proto-Oncogene 2, Transcription Factor	Protein Coding	1
7	ETV3	ETS Variant Transcription Factor 3	Protein Coding	1
8	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
9	HDAC1	Histone Deacetylase 1	Protein Coding	1
10	HDAC10	Histone Deacetylase 10	Protein Coding	1
11	HDAC11	Histone Deacetylase 11	Protein Coding	1
12	HDAC2	Histone Deacetylase 2	Protein Coding	1
13	HDAC3	Histone Deacetylase 3	Protein Coding	1
14	HDAC5	Histone Deacetylase 5	Protein Coding	1
15	HDAC6	Histone Deacetylase 6	Protein Coding	1
16	HDAC7	Histone Deacetylase 7	Protein Coding	1
17	HDAC8	Histone Deacetylase 8	Protein Coding	1
18	HDAC9	Histone Deacetylase 9	Protein Coding	1
19	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
20	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
21	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
22	NCOR2	Nuclear Receptor Corepressor 2	Protein Coding	1
23	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
24	RBL1	RB Transcriptional Corepressor Like 1	Protein Coding	1
25	RBL2	RB Transcriptional Corepressor Like 2	Protein Coding	1
26	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
27	SIN3B	SIN3 Transcription Regulator Family Member B	Protein Coding	1

Disorders associated with Macrophage Differentiation and Growth Inhibition by METS SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Witteveen-kolk syndrome	Enrichment	SIN3A, SIN3B	5.42
2	Lip and oral cavity carcinoma	Enrichment	HRAS, RB1	3.60
3	Bladder cancer	Enrichment	HRAS, RB1	2.82
4	Chondrodysplasia with platyspondyly, distinctive brachydactyly, hydrocephaly, and microphthalmia	Enrichment	HDAC6	2.70
5	Brunet-wagner neurodevelopmental syndrome	Enrichment	RBL2	2.70
6	Auriculocondylar syndrome 4	Enrichment	HDAC9	2.70
7	Cornelia de lange syndrome 5	Enrichment	HDAC8	2.70
8	Brain abnormalities, neurodegeneration, and dysosteosclerosis	Enrichment	CSF1R	2.70
9	Trilateral retinoblastoma	Enrichment	RB1	2.70
10	Csf1r-related disorder	Enrichment	CSF1R	2.70
11	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.70
12	Early-onset calcifying leukoencephalopathy-skeletal dysplasia	Enrichment	CSF1R	2.70
13	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.70
14	Lung oat cell carcinoma	Enrichment	RB1	2.70
15	Costello syndrome	Enrichment	HRAS	2.40
16	Chromosome 13q14 deletion syndrome	Enrichment	RB1	2.40
17	Syndactyly, type iii	Enrichment	HDAC8	2.40
18	Wilson-turner syndrome	Enrichment	HDAC8	2.40
19	Familial retinoblastoma	Enrichment	RB1	2.40
20	Wooly hair nevus	Enrichment	HRAS	2.40
21	Jacobsen syndrome	Enrichment	ETS1	2.22
22	Retinoblastoma	Enrichment	RB1	2.22
23	Leukoencephalopathy, hereditary diffuse, with spheroids 1	Enrichment	CSF1R	2.22
24	Osteogenic sarcoma	Enrichment	RB1	2.22
25	Woolly hair, autosomal recessive 3	Enrichment	RB1	2.22
26	Hypotrichosis 8	Enrichment	RB1	2.22
27	Large congenital melanocytic nevus	Enrichment	HRAS	2.22
28	Squamous cell carcinoma	Enrichment	RB1	2.22
29	Bone osteosarcoma	Enrichment	RB1	2.22
30	Spermatocytoma	Enrichment	HRAS	2.22
31	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS	2.10
32	Small cell cancer of the lung	Enrichment	RB1	2.10
33	Lynch syndrome 4	Enrichment	RB1	2.10
34	Congenital generalized lipodystrophy	Enrichment	FOS	2.10
35	Epidermolytic nevus	Enrichment	HRAS	2.10
36	Histiocytoid hemangioma	Enrichment	FOS	2.00
37	Nevus, epidermal	Enrichment	HRAS	1.86
38	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS	1.86
39	Noonan syndrome 3	Enrichment	HRAS	1.86
40	Follicular thyroid carcinoma	Enrichment	HRAS	1.86
41	Melanocytic nevus syndrome, congenital	Enrichment	HRAS	1.80
42	Fanconi anemia, complementation group c	Enrichment	HDAC8	1.80
43	Cornelia de lange syndrome 1	Enrichment	HDAC8	1.75
44	Arteriovenous malformation	Enrichment	HRAS	1.75
45	Cornelia de lange syndrome	Enrichment	HDAC8	1.75
46	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.70
47	Frontotemporal dementia 1	Enrichment	CSF1R	1.66
48	Atrial heart septal defect	Enrichment	HDAC8	1.66
49	Lung non-small cell carcinoma	Enrichment	HRAS	1.66
50	Interatrial communication	Enrichment	HDAC8	1.66
51	Alzheimer's disease	Enrichment	CSF1R	1.59
52	Lung cancer susceptibility 3	Enrichment	RB1	1.56
53	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS	1.53
54	Rhabdomyosarcoma	Enrichment	HRAS	1.50
55	Alzheimer disease, familial, 1	Enrichment	CSF1R	1.48
56	Polycystic kidney disease	Enrichment	HDAC8	1.45
57	Noonan syndrome 1	Enrichment	HRAS	1.35
58	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.30
59	Rasopathy	Enrichment	HRAS	1.30
60	Differentiated thyroid carcinoma	Enrichment	HRAS	1.25
61	Non-immune hydrops fetalis	Enrichment	HRAS	1.22
62	Systemic lupus erythematosus	Enrichment	ETS1	1.13
63	Myeloma, multiple	Enrichment	NCOR2	0.98
64	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	CSF1R	0.96
65	Breast cancer	Enrichment	JUN	0.86
66	Ovarian cancer	Enrichment	RB1	0.74
67	Microcephaly	Enrichment	HDAC8	0.66
68	Inherited cancer-predisposing syndrome	Enrichment	RB1	0.63

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Macrophage Differentiation and Growth Inhibition by METS

Pathway Network for Macrophage Differentiation and Growth Inhibition by METS

Member Pathways for Macrophage Differentiation and Growth Inhibition by METS

Pathways in the Macrophage Differentiation and Growth Inhibition by METS SuperPath

Associated Genes for Macrophage Differentiation and Growth Inhibition by METS

Associated Disorders for Macrophage Differentiation and Growth Inhibition by METS

Disorders associated with Macrophage Differentiation and Growth Inhibition by METS SuperPath

STRING Interaction Network for Macrophage Differentiation and Growth Inhibition by METS

Sources for Macrophage Differentiation and Growth Inhibition by METS