Maturation of protein E

Pathway network for the Maturation of protein E SuperPath

Sources:

Reactome

Pathways in the Maturation of protein E SuperPath

#	Name	Source	Genes
1	Maturation of protein E	Reactome	RPS27A UBA52 UBB UBC
2	Maturation of protein E	Reactome	RPS27A UBA52 UBB UBC
3	Josephin domain DUBs	Reactome	ATXN3 ATXN3L JOSD1 JOSD2 PRKN RAD23A RAD23B RPS27A UBA52 UBB UBC VCP (see all 12) (see less)

Gene overlap in member pathways for Maturation of protein E SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	RPS27A	Ribosomal Protein S27a	Protein Coding	3
2	UBA52	Ubiquitin A-52 Residue Ribosomal Protein Fusion Product 1	Protein Coding	3
3	UBB	Ubiquitin B	Protein Coding	3
4	UBC	Ubiquitin C	Protein Coding	3
5	JOSD2	Josephin Domain Containing 2	Protein Coding	1
6	ATXN3	Ataxin 3	Protein Coding	1
7	PRKN	Parkin RBR E3 Ubiquitin Protein Ligase	Protein Coding	1
8	RAD23A	RAD23 Nucleotide Excision Repair Protein A	Protein Coding	1
9	RAD23B	RAD23 Nucleotide Excision Repair Protein B	Protein Coding	1
10	VCP	Valosin Containing Protein	Protein Coding	1
11	ATXN3L	Ataxin 3 Like	Protein Coding	1
12	JOSD1	Josephin Domain Containing 1	Protein Coding	1

Disorders associated with Maturation of protein E SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Severe acute respiratory syndrome	Direct
2	Covid-19	Direct
3	Parkinson's disease	Enrichment	ATXN3, PRKN	3.91
4	Parkinson disease, late-onset	Enrichment	ATXN3, PRKN	3.71
5	Inclusion body myopathy with early-onset paget disease with or without frontotemporal dementia 1	Enrichment	VCP	3.05
6	Leprosy 2	Enrichment	PRKN	3.05
7	Frontotemporal dementia and/or amyotrophic lateral sclerosis 6	Enrichment	VCP	3.05
8	Multisystem proteinopathy	Enrichment	VCP	3.05
9	Adult-onset distal myopathy due to vcp mutation	Enrichment	VCP	3.05
10	Parkinson disease 12	Enrichment	PRKN	2.75
11	Amyotrophic lateral sclerosis 6 with or without frontotemporal dementia	Enrichment	VCP	2.75
12	Submucosal cleft palate	Enrichment	UBB	2.75
13	Cleft hard palate	Enrichment	UBB	2.75
14	Spastic paraplegia-paget disease of bone syndrome	Enrichment	VCP	2.75
15	Uvula, bifid	Enrichment	UBB	2.58
16	Cleft soft palate	Enrichment	UBB	2.58
17	Inclusion body myopathy with paget disease of bone and frontotemporal dementia	Enrichment	VCP	2.58
18	Complex hereditary spastic paraplegia	Enrichment	PRKN	2.45
19	Dementia, lewy body	Enrichment	VCP	2.35
20	Parkinson disease 2, autosomal recessive juvenile	Enrichment	PRKN	2.35
21	Charcot-marie-tooth disease, axonal, type 2e	Enrichment	VCP	2.35
22	Parkin type of early-onset parkinson disease	Enrichment	PRKN	2.35
23	Machado-joseph disease	Enrichment	ATXN3	2.28
24	Progressive non-fluent aphasia	Enrichment	VCP	2.10
25	Behavioral variant of frontotemporal dementia	Enrichment	VCP	2.10
26	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	VCP	2.05
27	Early-onset parkinson's disease	Enrichment	PRKN	1.98
28	Alzheimer's disease	Enrichment	VCP	1.94
29	Lung cancer susceptibility 3	Enrichment	PRKN	1.91
30	Alzheimer disease, familial, 1	Enrichment	VCP	1.83
31	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	VCP	1.78
32	Lung cancer	Enrichment	PRKN	1.55
33	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	VCP	1.30
34	Schizophrenia	Enrichment	PRKN	1.29
35	Autism	Enrichment	PRKN	1.21
36	Ovarian cancer	Enrichment	PRKN	1.07
37	Autism spectrum disorder	Enrichment	PRKN	1.03

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Maturation of protein E

Pathway Network for Maturation of protein E

Pathway network for the Maturation of protein E SuperPath

Member Pathways for Maturation of protein E

Pathways in the Maturation of protein E SuperPath

Gene overlap in member pathways for Maturation of protein E SuperPath

Associated Genes for Maturation of protein E

Associated Disorders for Maturation of protein E

Disorders associated with Maturation of protein E SuperPath

STRING Interaction Network for Maturation of protein E

Sources for Maturation of protein E