MECP2 and associated Rett syndrome

No Pathway Network information available for MECP2 and associated Rett syndrome

Pathways in the MECP2 and associated Rett syndrome SuperPath

#	Name	Source	Genes
1	MECP2 and associated Rett syndrome	WikiPathways	AKT1 APOC2 ARHGEF26 BCL6 BDNF CAMK2A CDON CEBPD CNP CREB1 CSRP1 CTCF DHX9 DLX5 DLX6 E2F1 EZH2 FGF2 FGF3 FGF4 FGF5 FKBP5 FOXG1 FUS FUT8 GABRR2 GAD1 GAMT GPRIN1 GRIA1 GRIA3 GRIA4 GRID1 GRIN1 HDAC1 HNRNPF HNRNPH1 IGF1 IGF1R IGF2 MAG MBP MECP2 MEF2C MPP1 MTOR MYT1 NCOR1 NF1 NREP OPRK1 POU3F2 POU4F1 PRPF38A PSIP1 PTEN RBFOX1 REST RPS6 SGK1 SIN3A SMC3 SP1 SP3 SST TAF1 TAP1 TARDBP TET1 TET2 TET3 UBE3A YBX1 (see all 73) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	FUT8	Fucosyltransferase 8	Protein Coding	1
2	NCOR1	Nuclear Receptor Corepressor 1	Protein Coding	1
3	NREP	Neuronal Regeneration Related Protein	Protein Coding	1
4	SMC3	Structural Maintenance Of Chromosomes 3	Protein Coding	1
5	CAMK2A	Calcium/Calmodulin Dependent Protein Kinase II Alpha	Protein Coding	1
6	TET1	Tet Methylcytosine Dioxygenase 1	Protein Coding	1
7	UBE3A	Ubiquitin Protein Ligase E3A	Protein Coding	1
8	TAP1	Transporter 1, ATP Binding Cassette Subfamily B Member	Protein Coding	1
9	TAF1	TATA-Box Binding Protein Associated Factor 1	Protein Coding	1
10	SST	Somatostatin	Protein Coding	1
11	SP1	Sp1 Transcription Factor	Protein Coding	1
12	SGK1	Serum/Glucocorticoid Regulated Kinase 1	Protein Coding	1
13	BDNF	Brain Derived Neurotrophic Factor	Protein Coding	1
14	RPS6	Ribosomal Protein S6	Protein Coding	1
15	BCL6	BCL6 Transcription Repressor	Protein Coding	1
16	REST	RE1 Silencing Transcription Factor	Protein Coding	1
17	PTEN	Phosphatase And Tensin Homolog	Protein Coding	1
18	TET2	Tet Methylcytosine Dioxygenase 2	Protein Coding	1
19	RBFOX1	RNA Binding Fox-1 Homolog 1	Protein Coding	1
20	POU4F1	POU Class 4 Homeobox 1	Protein Coding	1
21	POU3F2	POU Class 3 Homeobox 2	Protein Coding	1
22	CDON	Cell Adhesion Associated, Oncogene Regulated	Protein Coding	1
23	OPRK1	Opioid Receptor Kappa 1	Protein Coding	1
24	YBX1	Y-Box Binding Protein 1	Protein Coding	1
25	NF1	Neurofibromin 1	Protein Coding	1
26	MPP1	MAGUK P55 Scaffold Protein 1	Protein Coding	1
27	MEF2C	Myocyte Enhancer Factor 2C	Protein Coding	1
28	MECP2	Methyl-CpG Binding Protein 2	Protein Coding	1
29	MBP	Myelin Basic Protein	Protein Coding	1
30	MAG	Myelin Associated Glycoprotein	Protein Coding	1
31	IGF2	Insulin Like Growth Factor 2	Protein Coding	1
32	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
33	IGF1	Insulin Like Growth Factor 1	Protein Coding	1
34	APOC2	Apolipoprotein C2	Protein Coding	1
35	HNRNPH1	Heterogeneous Nuclear Ribonucleoprotein H1	Protein Coding	1
36	HDAC1	Histone Deacetylase 1	Protein Coding	1
37	GRIN1	Glutamate Ionotropic Receptor NMDA Type Subunit 1	Protein Coding	1
38	GRID1	Glutamate Ionotropic Receptor Delta Type Subunit 1	Protein Coding	1
39	GRIA4	Glutamate Ionotropic Receptor AMPA Type Subunit 4	Protein Coding	1
40	GRIA3	Glutamate Ionotropic Receptor AMPA Type Subunit 3	Protein Coding	1
41	GRIA1	Glutamate Ionotropic Receptor AMPA Type Subunit 1	Protein Coding	1
42	SIN3A	SIN3 Transcription Regulator Family Member A	Protein Coding	1
43	GAMT	Guanidinoacetate N-Methyltransferase	Protein Coding	1
44	GAD1	Glutamate Decarboxylase 1	Protein Coding	1
45	GABRR2	Gamma-Aminobutyric Acid Type A Receptor Subunit Rho2	Protein Coding	1
46	FUS	FUS RNA Binding Protein	Protein Coding	1
47	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	1
48	TARDBP	TAR DNA Binding Protein	Protein Coding	1
49	FOXG1	Forkhead Box G1	Protein Coding	1
50	FKBP5	FKBP Prolyl Isomerase 5	Protein Coding	1
51	FGF5	Fibroblast Growth Factor 5	Protein Coding	1
52	FGF4	Fibroblast Growth Factor 4	Protein Coding	1
53	FGF3	Fibroblast Growth Factor 3	Protein Coding	1
54	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
55	EZH2	Enhancer Of Zeste 2 Polycomb Repressive Complex 2 Subunit	Protein Coding	1
56	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1
57	TET3	Tet Methylcytosine Dioxygenase 3	Protein Coding	1
58	E2F1	E2F Transcription Factor 1	Protein Coding	1
59	DLX6	Distal-Less Homeobox 6	Protein Coding	1
60	DLX5	Distal-Less Homeobox 5	Protein Coding	1
61	CSRP1	Cysteine And Glycine Rich Protein 1	Protein Coding	1
62	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
63	CNP	2'''',3''''-Cyclic Nucleotide 3'''' Phosphodiesterase	Protein Coding	1
64	PSIP1	PC4 And SRSF1 Interacting Protein 1	Protein Coding	1
65	CTCF	CCCTC-Binding Factor	Protein Coding	1
66	CEBPD	CCAAT Enhancer Binding Protein Delta	Protein Coding	1
67	DHX9	DExH-Box Helicase 9	Protein Coding	1
68	PRPF38A	Pre-MRNA Processing Factor 38A	Protein Coding	1
69	GPRIN1	G Protein Regulated Inducer Of Neurite Outgrowth 1	Protein Coding	1
70	SP3	Sp3 Transcription Factor	Protein Coding	1
71	MYT1	Myelin Transcription Factor 1	Protein Coding	1
72	HNRNPF	Heterogeneous Nuclear Ribonucleoprotein F	Protein Coding	1
73	ARHGEF26	Rho Guanine Nucleotide Exchange Factor 26	Protein Coding	1

Disorders associated with MECP2 and associated Rett syndrome SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Autism spectrum disorder	Enrichment	GRIA1, MECP2, MEF2C, NF1, PTEN, SMC3	4.59
2	Myeloma, multiple	Enrichment	NF1, SGK1, TET2, TET3	3.64
3	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	3.55
4	Hemimegalencephaly	Enrichment	MTOR, PTEN	3.55
5	Angelman syndrome	Enrichment	MECP2, UBE3A	3.37
6	Rett syndrome	Enrichment	FOXG1, MECP2	3.23
7	Rett syndrome, congenital variant	Enrichment	FOXG1, MECP2	3.11
8	Isolated split hand-split foot malformation	Enrichment	DLX5, DLX6	3.11
9	Cowden syndrome	Enrichment	AKT1, PTEN	3.00
10	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	FUS, TARDBP	2.90
11	Meningioma	Enrichment	AKT1, PTEN	2.74
12	Stereotypic movement disorder	Enrichment	FOXG1, MECP2	2.67
13	Autosomal dominant non-syndromic intellectual disability	Enrichment	CAMK2A, GRIA1, GRIN1	2.61
14	Congenital nervous system abnormality	Enrichment	FOXG1, GAMT, MECP2, PTEN	2.60
15	Nervous system disease	Enrichment	FOXG1, GAMT, MECP2, PTEN	2.60
16	Wilms tumor 1	Enrichment	IGF2, REST	2.54
17	Rhabdomyosarcoma	Enrichment	NF1, PTEN	2.49
18	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	FUS, MEF2C, TARDBP	2.43
19	Proteus syndrome	Enrichment	AKT1	2.27
20	Split-hand/foot malformation 1 with sensorineural hearing loss, autosomal recessive	Enrichment	DLX5	2.27
21	Intellectual developmental disorder, x-linked, syndromic 33	Enrichment	TAF1	2.27
22	Vacterl association with hydrocephalus	Enrichment	PTEN	2.27
23	Cornelia de lange syndrome 3 with or without midline brain defects	Enrichment	SMC3	2.27
24	Dystonia 3, torsion, x-linked	Enrichment	TAF1	2.27
25	Facial hypertrichosis	Enrichment	MECP2	2.27
26	Tremor, hereditary essential, 4	Enrichment	FUS	2.27
27	Wilms tumor 6	Enrichment	REST	2.27
28	Intellectual developmental disorder, x-linked, syndromic, lubs type	Enrichment	MECP2	2.27
29	Intellectual developmental disorder, autosomal recessive 63	Enrichment	CAMK2A	2.27
30	Autism x-linked 3	Enrichment	MECP2	2.27
31	Intellectual developmental disorder, x-linked, syndromic, wu type	Enrichment	GRIA3	2.27
32	Leukodystrophy, hypomyelinating, 20	Enrichment	CNP	2.27
33	Developmental and epileptic encephalopathy 89	Enrichment	GAD1	2.27
34	Neurodevelopmental disorder with hypotonia, stereotypic hand movements, and impaired language	Enrichment	MEF2C	2.27
35	Papillary tumor of the pineal region	Enrichment	PTEN	2.27
36	Familial isolated trichomegaly	Enrichment	FGF5	2.27
37	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal recessive	Enrichment	GRIN1	2.27
38	Deafness, autosomal dominant 27	Enrichment	REST	2.27
39	Holoprosencephaly 11	Enrichment	CDON	2.27
40	Cowden syndrome 6	Enrichment	AKT1	2.27
41	Syndromic x-linked intellectual disability lubs type	Enrichment	MECP2	2.27
42	Developmental and epileptic encephalopathy 101	Enrichment	GRIN1	2.27
43	Glioma susceptibility 2	Enrichment	PTEN	2.27
44	Neurodevelopmental disorder with or without hyperkinetic movements and seizures, autosomal dominant	Enrichment	GRIN1	2.27
45	Fibromatosis, gingival, 5	Enrichment	REST	2.27
46	Tet3-related beck-fahrner syndrome	Enrichment	TET3	2.27
47	Neurodevelopmental disorder with or without seizures and gait abnormalities	Enrichment	GRIA4	2.27
48	Ctcf-related disorder	Enrichment	CTCF	2.27
49	Spastic paraplegia 75, autosomal recessive	Enrichment	MAG	2.27
50	Intellectual developmental disorder, autosomal dominant 67	Enrichment	GRIA1	2.27
51	Beck-fahrner syndrome	Enrichment	TET3	2.27
52	Intellectual developmental disorder, autosomal dominant 53	Enrichment	CAMK2A	2.27
53	Intellectual developmental disorder, autosomal recessive 76	Enrichment	GRIA1	2.27
54	Plexiform neurofibroma	Enrichment	NF1	2.27
55	Neurofibroma	Enrichment	NF1	2.27
56	Short-rib thoracic dysplasia 22 without polydactyly	Enrichment	FGF4	2.27
57	Syndromic x-linked intellectual disability 94	Enrichment	GRIA3	2.27
58	Neurofibromatosis	Enrichment	NF1	2.27
59	Chromosome 15q24 deletion syndrome	Enrichment	SIN3A	2.27
60	X-linked intellectual disability-global development delay-facial dysmorphism-sacral caudal remnant syndrome	Enrichment	TAF1	2.27
61	5q14.3 microdeletion syndrome	Enrichment	MEF2C	2.27
62	Chromosome 17q11.2 deletion syndrome	Enrichment	NF1	2.27
63	Intellectual developmental disorder, autosomal dominant 75	Enrichment	DHX9	2.27
64	Optic nerve glioma	Enrichment	NF1	2.27
65	Complete atrioventricular septal defect without ventricular hypoplasia	Enrichment	MEF2C	2.27
66	Foxg1 syndrome due to intragenic alteration	Enrichment	FOXG1	2.27
67	Split hand-foot malformation 1 with sensorineural hearing loss	Enrichment	DLX5	2.27
68	Foxg1 syndrome due to 14q12 microdeletion	Enrichment	FOXG1	2.27
69	15q11q13 microduplication syndrome	Enrichment	UBE3A	2.27
70	Intellectual disability, autosomal dominant 8	Enrichment	GRIN1	2.27
71	Mef2c-related disorder	Enrichment	MEF2C	2.27
72	Segmental outgrowth-lipomatosis-arteriovenous malformation-epidermal nevus syndrome	Enrichment	PTEN	2.27
73	Tardbp-related predominantly upper-limb distal myopathy	Enrichment	TARDBP	2.27
74	Myelodysplastic neoplasm with increased blasts type 2	Enrichment	TET2	2.27
75	Myelodysplastic neoplasm with increased blasts type 1	Enrichment	TET2	2.27
76	Myelodysplastic neoplasm with low blasts	Enrichment	TET2	2.27
77	Bladder cancer	Enrichment	NF1, PTEN	1.98
78	Cafe-au-lait spots, multiple	Enrichment	NF1	1.97
79	Fibromatosis, gingival, 1	Enrichment	REST	1.97
80	Otodental dysplasia	Enrichment	FGF3	1.97
81	Apolipoprotein c-ii deficiency	Enrichment	APOC2	1.97
82	Trichomegaly	Enrichment	FGF5	1.97
83	Encephalopathy, neonatal severe, due to mecp2 mutations	Enrichment	MECP2	1.97
84	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.97
85	Amyotrophic lateral sclerosis 6 with or without frontotemporal dementia	Enrichment	FUS	1.97
86	Cerebral creatine deficiency syndrome 2	Enrichment	GAMT	1.97
87	Deafness, congenital, with inner ear agenesis, microtia, and microdontia	Enrichment	FGF3	1.97
88	Silver-russell syndrome 3	Enrichment	IGF2	1.97
89	Immunodeficiency 75 with lymphoproliferation	Enrichment	TET2	1.97
90	Ataxia, intention tremor, and hypotonia syndrome, childhood-onset	Enrichment	POU4F1	1.97
91	Congenital disorder of glycosylation with defective fucosylation 1	Enrichment	FUT8	1.97
92	Cebalid syndrome	Enrichment	MTOR	1.97
93	Chromosome 17q11.2 duplication syndrome, 1.4-mb	Enrichment	NF1	1.97
94	Intellectual developmental disorder, x-linked, syndromic 13	Enrichment	MECP2	1.97
95	Intravascular large b-cell lymphoma	Enrichment	BCL6	1.97
96	Cerebral creatine deficiency syndrome	Enrichment	GAMT	1.97
97	Bilateral generalized polymicrogyria	Enrichment	GRIN1	1.97
98	Intellectual developmental disorder, autosomal dominant 21	Enrichment	CTCF	1.97
99	Familial apolipoprotein c-ii deficiency	Enrichment	APOC2	1.97
100	X-linked intellectual disability-psychosis-macroorchidism syndrome	Enrichment	MECP2	1.97
101	Witteveen-kolk syndrome	Enrichment	SIN3A	1.97
102	Bardet-biedl syndrome 9	Enrichment	NF1	1.97
103	Neurodevelopmental disorder with craniofacial dysmorphism and skeletal defects	Enrichment	HNRNPH1	1.97
104	Smith-kingsmore syndrome	Enrichment	MTOR	1.97
105	Vacterl with hydrocephalus	Enrichment	PTEN	1.97
106	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.97
107	Creatine deficiency disorders	Enrichment	GAMT	1.97
108	Primary mediastinal large b-cell lymphoma	Enrichment	BCL6	1.97
109	Angelman syndrome due to maternal 15q11q13 deletion	Enrichment	UBE3A	1.97
110	Juvenile polyposis of infancy	Enrichment	PTEN	1.97
111	Silver-russell syndrome due to an imprinting defect of 11p15	Enrichment	IGF2	1.97
112	Pleomorphic rhabdomyosarcoma	Enrichment	NF1	1.97
113	Progressive bulbar palsy	Enrichment	MECP2	1.97
114	Oculootodental syndrome	Enrichment	FGF3	1.97
115	Silver-russell syndrome due to 11p15 microduplication	Enrichment	IGF2	1.97
116	Bruxism	Enrichment	MECP2	1.97
117	Colorectal cancer	Enrichment	AKT1, IGF2, RBFOX1	1.94
118	Dystonia	Enrichment	GRIA3, MECP2	1.82
119	Laryngomalacia	Enrichment	MECP2	1.79
120	Myopia 2, autosomal dominant	Enrichment	CNP	1.79
121	Watson syndrome	Enrichment	NF1	1.79
122	Weaver syndrome	Enrichment	EZH2	1.79
123	Neurofibromatosis, familial spinal	Enrichment	NF1	1.79
124	Chromosome 17q11.2 deletion syndrome, 1.4-mb	Enrichment	NF1	1.79
125	Cerebellar dysfunction with variable cognitive and behavioral abnormalities	Enrichment	POU4F1	1.79
126	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	BCL6	1.79
127	Myxoid liposarcoma	Enrichment	FUS	1.79
128	Brain cancer	Enrichment	NF1	1.79
129	Laryngeal squamous cell carcinoma	Enrichment	PTEN	1.79
130	Desmoplastic/nodular medulloblastoma	Enrichment	CTCF	1.79
131	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.79
132	Myxofibrosarcoma	Enrichment	FUS	1.79
133	Melanoma of soft tissue	Enrichment	CREB1	1.79
134	Myelodysplastic syndrome with ring sideroblasts	Enrichment	TET2	1.79
135	Angelman syndrome due to imprinting defect in 15q11-q13	Enrichment	UBE3A	1.79
136	Beckwith-wiedemann syndrome due to imprinting defect of 11p15	Enrichment	IGF2	1.79
137	Benign epilepsy with centrotemporal spikes	Enrichment	GRIN1, RBFOX1	1.69
138	Intellectual developmental disorder, x-linked, syndromic, bain type	Enrichment	HNRNPH1	1.67
139	Neurofibromatosis-noonan syndrome	Enrichment	NF1	1.67
140	Focal cortical dysplasia, type ii	Enrichment	MTOR	1.67
141	Mhc class i deficiency 1	Enrichment	TAP1	1.67
142	Neurodevelopmental disorder with progressive spasticity and brain white matter abnormalities	Enrichment	GAD1	1.67
143	Mhc class i deficiency	Enrichment	TAP1	1.67
144	Embryonal rhabdomyosarcoma	Enrichment	NF1	1.67
145	Pilocytic astrocytoma	Enrichment	NF1	1.67
146	Spastic quadriplegic cerebral palsy	Enrichment	GAD1	1.67
147	Sick sinus syndrome	Enrichment	MECP2	1.67
148	Intellectual disability, x-linked, syndromic, bain type	Enrichment	HNRNPH1	1.67
149	Silver-russell syndrome due to a point mutation	Enrichment	IGF2	1.67
150	Immunodeficiency by defective expression of mhc class i	Enrichment	TAP1	1.67
151	Systemic mastocytosis with associated hematologic neoplasm	Enrichment	TET2	1.67
152	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	1.67
153	Glioma	Enrichment	PTEN	1.67
154	Middle aortic syndrome	Enrichment	NF1	1.67
155	Gingival fibromatosis	Enrichment	REST	1.67
156	Centralopathic epilepsy	Enrichment	GRIN1, RBFOX1	1.65
157	Gastric cancer	Enrichment	NF1, PTEN	1.65
158	West syndrome	Enrichment	GRIA3, GRIN1	1.63
159	Hereditary breast carcinoma	Enrichment	AKT1, PTEN	1.63
160	Rhabdomyosarcoma 2	Enrichment	NF1	1.57
161	Macrocephaly/autism syndrome	Enrichment	PTEN	1.57
162	Major depressive disorder	Enrichment	FKBP5	1.57
163	Amyotrophic lateral sclerosis 10 with or without frontotemporal dementia	Enrichment	TARDBP	1.57
164	Follicular lymphoma	Enrichment	BCL6	1.57
165	Hemangioma	Enrichment	PTEN	1.57
166	Acute megakaryocytic leukemia	Enrichment	PTEN	1.57
167	Aggressive systemic mastocytosis	Enrichment	TET2	1.57
168	Body mass index quantitative trait locus 11	Enrichment	BDNF, GRIA4	1.53
169	Cowden syndrome 1	Enrichment	PTEN	1.50
170	Split-hand/foot malformation 1	Enrichment	DLX5	1.50
171	Hemihyperplasia, isolated	Enrichment	IGF2	1.50
172	Wilms tumor, aniridia, genitourinary anomalies, and impaired intellectual development syndrome	Enrichment	BDNF	1.50
173	Wiedemann-steiner syndrome	Enrichment	SMC3	1.50
174	Breast adenocarcinoma	Enrichment	AKT1	1.50
175	Inherited cancer-predisposing syndrome	Enrichment	EZH2, NF1, PTEN	1.47
176	Hereditary breast ovarian cancer syndrome	Enrichment	NF1, PTEN	1.45
177	Undetermined early-onset epileptic encephalopathy	Enrichment	FOXG1, RBFOX1	1.44
178	Thyroid cancer, nonmedullary, 2	Enrichment	PTEN	1.43
179	Silver-russell syndrome 1	Enrichment	IGF2	1.43
180	Myelofibrosis	Enrichment	TET2	1.43
181	Squamous cell carcinoma, head and neck	Enrichment	PTEN	1.43
182	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.43
183	Third-degree atrioventricular block	Enrichment	TET2	1.43
184	Essential thrombocythemia	Enrichment	TET2	1.43
185	Motor neuron disease	Enrichment	TARDBP	1.43
186	Focal epilepsy	Enrichment	MECP2	1.43
187	Follicular thyroid carcinoma	Enrichment	PTEN	1.43
188	Overgrowth syndrome	Enrichment	MTOR	1.43
189	Autosomal recessive non-syndromic intellectual disability	Enrichment	GRIA1, GRIN1	1.41
190	Ewing sarcoma	Enrichment	NF1	1.37
191	Cornelia de lange syndrome 1	Enrichment	SMC3	1.32
192	Neurofibromatosis, type i	Enrichment	NF1	1.32
193	Leukemia, acute lymphoblastic 3	Enrichment	NF1	1.32
194	Atypical chronic myeloid leukemia, bcr-abl1 negative	Enrichment	TET2	1.32
195	Congenital central hypoventilation syndrome	Enrichment	BDNF	1.32
196	Cornelia de lange syndrome	Enrichment	SMC3	1.32
197	Juvenile amyotrophic lateral sclerosis	Enrichment	FUS	1.32
198	Optic nerve disease	Enrichment	FOXG1	1.28
199	Melanoma	Enrichment	PTEN	1.28
200	Autism	Enrichment	MECP2, RBFOX1	1.24
201	Asthma	Enrichment	FKBP5	1.24
202	Meningioma, familial	Enrichment	PTEN	1.24
203	Myelodysplastic syndrome	Enrichment	TET2	1.24
204	Uterine corpus cancer	Enrichment	PTEN	1.24
205	Breast cancer	Enrichment	AKT1, PTEN	1.21
206	Juvenile myelomonocytic leukemia	Enrichment	NF1	1.20
207	Microphthalmia/coloboma 12	Enrichment	CDON	1.17
208	Nk-cell enteropathy	Enrichment	IGF1R	1.17
209	Pheochromocytoma	Enrichment	NF1	1.14
210	Pituitary stalk interruption syndrome	Enrichment	CDON	1.14
211	Coloboma of macula	Enrichment	CDON	1.11
212	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.11
213	Rare genetic intellectual disability	Enrichment	MTOR	1.11
214	Septopreoptic holoprosencephaly	Enrichment	CDON	1.11
215	Midline interhemispheric variant of holoprosencephaly	Enrichment	CDON	1.11
216	Isolated congenital microcephaly	Enrichment	FOXG1	1.08
217	Microform holoprosencephaly	Enrichment	CDON	1.08
218	Lobar holoprosencephaly	Enrichment	CDON	1.08
219	Alobar holoprosencephaly	Enrichment	CDON	1.06
220	Beckwith-wiedemann syndrome	Enrichment	IGF2	1.03
221	Early infantile developmental and epileptic encephalopathy	Enrichment	GRIN1	1.03
222	Semilobar holoprosencephaly	Enrichment	CDON	1.03
223	Diffuse large b-cell lymphoma	Enrichment	PTEN	1.01
224	Parkinson's disease	Enrichment	GAMT	1.01
225	Ovarian cancer	Enrichment	AKT1, PTEN	0.99
226	Endometrial cancer	Enrichment	PTEN	0.97
227	Lissencephaly	Enrichment	FOXG1	0.97
228	Hereditary paraganglioma-pheochromocytoma syndromes	Enrichment	NF1	0.97
229	Attention deficit-hyperactivity disorder	Enrichment	MECP2	0.95
230	Skin disease	Enrichment	NF1	0.95
231	Parkinson disease, late-onset	Enrichment	GAMT	0.92
232	Developmental and epileptic encephalopathy 1	Enrichment	GRIN1	0.90
233	Rasopathy	Enrichment	NF1	0.88
234	Strabismus	Enrichment	FOXG1	0.87
235	Microcephaly	Enrichment	IGF1R, MECP2	0.85
236	Prostate cancer	Enrichment	PTEN	0.84
237	Non-syndromic x-linked intellectual disability	Enrichment	MECP2	0.75
238	Developmental and epileptic encephalopathy	Enrichment	GRIA3	0.75
239	Systemic lupus erythematosus	Enrichment	MECP2	0.72
240	Leukemia, acute myeloid	Enrichment	TET2	0.71
241	Epilepsy	Enrichment	MECP2	0.71
242	Charcot-marie-tooth disease	Enrichment	DHX9	0.70
243	Rare autosomal dominant non-syndromic sensorineural deafness type dfna	Enrichment	REST	0.61
244	Schizophrenia	Enrichment	RBFOX1	0.56
245	Complex neurodevelopmental disorder	Enrichment	GRIA4	0.31

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

MECP2 and associated Rett syndrome

Pathway Network for MECP2 and associated Rett syndrome

Member Pathways for MECP2 and associated Rett syndrome

Pathways in the MECP2 and associated Rett syndrome SuperPath

Associated Genes for MECP2 and associated Rett syndrome

Associated Disorders for MECP2 and associated Rett syndrome

Disorders associated with MECP2 and associated Rett syndrome SuperPath

STRING Interaction Network for MECP2 and associated Rett syndrome

Sources for MECP2 and associated Rett syndrome