Metabolic pathways of fibroblasts

No Pathway Network information available for Metabolic pathways of fibroblasts

Pathways in the Metabolic pathways of fibroblasts SuperPath

#	Name	Source	Genes
1	Metabolic pathways of fibroblasts	WikiPathways	ALDH18A1 BMP1 GCK GLS GLUD1 LPAR1 PGM1 PHGDH PLCG1 PSAT1 PSPH PYCR1 RHOA SLC16A1 SLC2A1 UGDH UGP2 (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BMP1	Bone Morphogenetic Protein 1	Protein Coding	1
2	ALDH18A1	Aldehyde Dehydrogenase 18 Family Member A1	Protein Coding	1
3	GLUD1	Glutamate Dehydrogenase 1	Protein Coding	1
4	PYCR1	Pyrroline-5-Carboxylate Reductase 1	Protein Coding	1
5	GLS	Glutaminase	Protein Coding	1
6	UGDH	UDP-Glucose 6-Dehydrogenase	Protein Coding	1
7	PSAT1	Phosphoserine Aminotransferase 1	Protein Coding	1
8	PSPH	Phosphoserine Phosphatase	Protein Coding	1
9	PHGDH	Phosphoglycerate Dehydrogenase	Protein Coding	1
10	PGM1	Phosphoglucomutase 1	Protein Coding	1
11	UGP2	UDP-Glucose Pyrophosphorylase 2	Protein Coding	1
12	PLCG1	Phospholipase C Gamma 1	Protein Coding	1
13	RHOA	Ras Homolog Family Member A	Protein Coding	1
14	SLC16A1	Solute Carrier Family 16 Member 1	Protein Coding	1
15	SLC2A1	Solute Carrier Family 2 Member 1	Protein Coding	1
16	GCK	Glucokinase	Protein Coding	1
17	LPAR1	Lysophosphatidic Acid Receptor 1	Protein Coding	1

Disorders associated with Metabolic pathways of fibroblasts SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hyperinsulinemic hypoglycemia, familial, 1	Enrichment	GCK, GLUD1	4.66
2	Nonsyndromic genetic hyperinsulinism	Enrichment	GCK, GLUD1	4.66
3	Neu-laxova syndrome 1	Enrichment	PHGDH	2.90
4	Spastic paraplegia 9a, autosomal dominant	Enrichment	ALDH18A1	2.90
5	Phosphoglycerate dehydrogenase deficiency	Enrichment	PHGDH	2.90
6	Stomatin-deficient cryohydrocytosis with neurologic defects	Enrichment	SLC2A1	2.90
7	Maturity-onset diabetes of the young, type 2	Enrichment	GCK	2.90
8	Erythrocyte lactate transporter defect	Enrichment	SLC16A1	2.90
9	Cutis laxa, autosomal recessive, type iiia	Enrichment	ALDH18A1	2.90
10	Cutis laxa, autosomal recessive, type iiib	Enrichment	PYCR1	2.90
11	Spastic paraplegia 9b, autosomal recessive	Enrichment	ALDH18A1	2.90
12	Casgid syndrome	Enrichment	GLS	2.90
13	Immune dysregulation, autoimmunity, and autoinflammation	Enrichment	PLCG1	2.90
14	Phosphoserine aminotransferase deficiency	Enrichment	PSAT1	2.90
15	Hyperinsulinemic hypoglycemia, familial, 3	Enrichment	GCK	2.90
16	Cutis laxa, autosomal dominant 3	Enrichment	ALDH18A1	2.90
17	Hyperinsulinemic hypoglycemia, familial, 6	Enrichment	GLUD1	2.90
18	Developmental and epileptic encephalopathy 71	Enrichment	GLS	2.90
19	Epilepsy, idiopathic generalized 12	Enrichment	SLC2A1	2.90
20	Developmental and epileptic encephalopathy 84	Enrichment	UGDH	2.90
21	Phosphoserine phosphatase deficiency	Enrichment	PSPH	2.90
22	Autosomal recessive cutis laxa type iii	Enrichment	ALDH18A1	2.90
23	Cutis laxa, autosomal recessive, type iib	Enrichment	PYCR1	2.90
24	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.90
25	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.90
26	Developmental and epileptic encephalopathy 83	Enrichment	UGP2	2.90
27	Neu-laxova syndrome 2	Enrichment	PSAT1	2.90
28	Gestational diabetes	Enrichment	GCK	2.90
29	Spastic ataxia-dysarthria due to glutaminase deficiency	Enrichment	GLS	2.90
30	Epilepsy with myoclonic absences	Enrichment	SLC2A1	2.90
31	Neurometabolic disorder due to serine deficiency	Enrichment	PSAT1	2.90
32	Neu-laxova syndrome due to 3-phosphoserine phosphatase deficiency	Enrichment	PSPH	2.90
33	Hereditary cryohydrocytosis with reduced stomatin	Enrichment	SLC2A1	2.90
34	Autosomal dominant complex spastic paraplegia type 9b	Enrichment	ALDH18A1	2.90
35	West syndrome	Enrichment	SLC2A1, UGDH	2.87
36	Maturity-onset diabetes of the young, type 1	Enrichment	GCK	2.60
37	Dystonia 9	Enrichment	SLC2A1	2.60
38	Glut1 deficiency syndrome 1	Enrichment	SLC2A1	2.60
39	Diabetes mellitus, permanent neonatal, 1	Enrichment	GCK	2.60
40	Bone marrow failure syndrome 2	Enrichment	GCK	2.60
41	Monocarboxylate transporter 1 deficiency	Enrichment	SLC16A1	2.60
42	Osteogenesis imperfecta, type xiii	Enrichment	BMP1	2.60
43	Congenital disorder of glycosylation, type it	Enrichment	PGM1	2.60
44	Global developmental delay, progressive ataxia, and elevated glutamine	Enrichment	GLS	2.60
45	Spastic paraplegia 5a, autosomal recessive	Enrichment	ALDH18A1	2.60
46	Glucose transporter type 1 deficiency syndrome	Enrichment	SLC2A1	2.60
47	Hyperinsulinemic hypoglycemia, familial, 7	Enrichment	SLC16A1	2.60
48	Ketoacidosis due to monocarboxylate transporter-1 deficiency	Enrichment	SLC16A1	2.60
49	Nijmegen breakage syndrome	Enrichment	GCK	2.43
50	Geroderma osteodysplasticum	Enrichment	PYCR1	2.43
51	Glut1 deficiency syndrome 2	Enrichment	SLC2A1	2.43
52	Chromosome 17q23.1-q23.2 deletion syndrome	Enrichment	SLC2A1	2.43
53	Autosomal dominant cutis laxa	Enrichment	ALDH18A1	2.43
54	High bone mass osteogenesis imperfecta	Enrichment	BMP1	2.43
55	Maturity-onset diabetes of the young, type 3	Enrichment	GCK	2.30
56	Hemihyperplasia, isolated	Enrichment	RHOA	2.13
57	Paroxysmal dystonia	Enrichment	SLC2A1	2.06
58	Alternating hemiplegia of childhood	Enrichment	SLC2A1	2.00
59	Permanent neonatal diabetes mellitus	Enrichment	GCK	2.00
60	Myoclonic-atonic epilepsy	Enrichment	SLC2A1	1.95
61	Diabetes mellitus	Enrichment	GCK	1.86
62	Cutis laxa	Enrichment	PYCR1	1.83
63	Osteogenesis imperfecta, type iii	Enrichment	BMP1	1.73
64	Congenital disorder of glycosylation, type in	Enrichment	PGM1	1.68
65	Esophageal atresia/tracheoesophageal fistula	Enrichment	GLS	1.63
66	Maturity-onset diabetes of the young	Enrichment	GCK	1.61
67	Brittle bone disorder	Enrichment	BMP1	1.55
68	Developmental and epileptic encephalopathy 1	Enrichment	SLC2A1	1.51
69	Strabismus	Enrichment	SLC2A1	1.48
70	Connective tissue disease	Enrichment	PYCR1	1.40
71	Epilepsy	Enrichment	SLC2A1	1.31
72	Benign epilepsy with centrotemporal spikes	Enrichment	SLC2A1	1.30
73	Type 2 diabetes mellitus	Enrichment	GCK	1.29
74	Hereditary spastic paraplegia	Enrichment	ALDH18A1	1.29
75	Centralopathic epilepsy	Enrichment	SLC2A1	1.28
76	Congenital nervous system abnormality	Enrichment	ALDH18A1	0.90
77	Nervous system disease	Enrichment	ALDH18A1	0.90
78	Microcephaly	Enrichment	SLC2A1	0.84

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Metabolic pathways of fibroblasts

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Pathways in the Metabolic pathways of fibroblasts SuperPath

Associated Genes for Metabolic pathways of fibroblasts

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Disorders associated with Metabolic pathways of fibroblasts SuperPath

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