Methylene Blue Pathway, Pharmacodynamics

No Pathway Network information available for Methylene Blue Pathway, Pharmacodynamics

#	Name	Source	Genes
1	Methylene Blue Pathway, Pharmacodynamics	PharmGKB	BLVRB CYB5A CYB5R3 G6PD

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BLVRB	Biliverdin Reductase B	Protein Coding	1
2	G6PD	Glucose-6-Phosphate Dehydrogenase	Protein Coding	1
3	CYB5R3	Cytochrome B5 Reductase 3	Protein Coding	1
4	CYB5A	Cytochrome B5 Type A	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Hereditary methemoglobinemia	Enrichment	CYB5A, CYB5R3	7.19
2	Congenital nonspherocytic hemolytic anemia	Enrichment	G6PD	3.53
3	Methemoglobinemia and ambiguous genitalia	Enrichment	CYB5A	3.23
4	Methemoglobinemia due to deficiency of methemoglobin reductase	Enrichment	CYB5R3	3.23
5	Congenital hemolytic anemia	Enrichment	G6PD	3.23
6	Glucosephosphate dehydrogenase deficiency	Enrichment	G6PD	3.23
7	Adrenal hyperplasia, congenital, due to 17-alpha-hydroxylase deficiency	Enrichment	CYB5A	3.05
8	Congenital myopathy 1a, autosomal dominant, with malignant hyperthermia	Enrichment	CYB5R3	2.93
9	Congenital myopathy 1a	Enrichment	CYB5R3	2.93
10	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	G6PD	2.83
11	Coronary heart disease 5	Enrichment	G6PD	2.58
12	Malaria	Enrichment	G6PD	2.17

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for Methylene Blue Pathway, Pharmacodynamics