Microglia pathogen phagocytosis pathway

No Pathway Network information available for Microglia pathogen phagocytosis pathway

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

Disorders associated with Microglia pathogen phagocytosis pathway SuperPath

according to GeneCards Suite gene sharing
#DisorderTypeGenesScore
1Chronic granulomatous diseaseEnrichmentCYBA, CYBB, NCF1, NCF2, NCF410.56
2C1q deficiency 1EnrichmentC1QA, C1QB, C1QC7.62
3Immunodeficiency due to a classical component pathway complement deficiencyEnrichmentC1QA, C1QB, C1QC5.88
4Ehlers-danlos syndrome, arthrochalasia type, 2EnrichmentCOL1A1, COL1A25.19
5Ehlers-danlos/osteogenesis imperfecta syndromeEnrichmentCOL1A1, COL1A25.19
6Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 1EnrichmentTREM2, TYROBP5.07
7Congenital lipomatous overgrowth, vascular malformations, and epidermal neviEnrichmentPIK3CA, PIK3R14.71
8High bone mass osteogenesis imperfectaEnrichmentCOL1A1, COL1A24.71
9Granulomatous disease, chronic, autosomal recessive, 2EnrichmentNCF1, NCF24.60
10Immunodeficiency 14a with lymphoproliferation, autosomal dominantEnrichmentPIK3CD, PIK3R14.60
11Immunodeficiency 14EnrichmentPIK3CD, PIK3R14.60
12Ehlers-danlos syndrome, arthrochalasia type, 1EnrichmentCOL1A1, COL1A24.41
13Megalencephaly-capillary malformation-polymicrogyria syndromeEnrichmentPIK3CA, PIK3R24.41
14Noonan syndrome-like disorder with or without juvenile myelomonocytic leukemiaEnrichmentCDC42, PTPN114.41
15Osteogenesis imperfecta with normal sclerae, dominant formEnrichmentCOL1A1, COL1A24.41
16Granulomatous disease, chronic, x-linkedEnrichmentCYBB, NCF14.30
17Ehlers-danlos syndrome, classic type, 1EnrichmentCOL1A1, COL1A24.02
18Osteogenesis imperfecta, type iEnrichmentCOL1A1, COL1A24.02
19Hemihyperplasia, isolatedEnrichmentPIK3CA, RHOA4.02
20Classic ehlers-danlos syndromeEnrichmentCOL1A1, COL1A24.02
21Osteogenesis imperfecta, type iiEnrichmentCOL1A1, COL1A23.87
22Primary bone dysplasiaEnrichmentCOL1A1, COL1A23.54
23OsteochondrodysplasiaEnrichmentCOL1A1, COL1A23.46
24Autosomal non-syndromic agammaglobulinemiaEnrichmentPIK3CD, PIK3R13.42
25Osteogenesis imperfecta, type ivEnrichmentCOL1A1, COL1A23.30
26Chromosome 1p36 deletion syndromeEnrichmentPDPN, PRKCZ3.30
27OsteoporosisEnrichmentCOL1A1, COL1A23.24
28Osteogenesis imperfecta, type iiiEnrichmentCOL1A1, COL1A23.18
29Ehlers-danlos syndromeEnrichmentCOL1A1, COL1A22.97
30Brittle bone disorderEnrichmentCOL1A1, COL1A22.80
31MacrodactylyEnrichmentPIK3CA2.59
32MetachondromatosisEnrichmentPTPN112.59
33Ehlers-danlos syndrome, cardiac valvular typeEnrichmentCOL1A22.59
34Immunodeficiency 73a with defective neutrophil chemotaxis and leukocytosisEnrichmentRAC22.59
35Megalencephaly, autosomal dominantEnrichmentPIK3CA2.59
36Leopard syndrome 1EnrichmentPTPN112.59
37Cowden syndrome 5EnrichmentPIK3CA2.59
38Ataxia-oculomotor apraxia 3EnrichmentPIK3R52.59
39Bleeding disorder, platelet-type, 11EnrichmentGP62.59
40Cerebral cavernous malformations 4EnrichmentPIK3CA2.59
41Immunodeficiency 81EnrichmentLCP22.59
42Immunodeficiency 82 with systemic inflammationEnrichmentSYK2.59
43Short syndromeEnrichmentPIK3R12.59
44Combined osteogenesis imperfecta and ehlers-danlos syndrome 2EnrichmentCOL1A22.59
45Immunodeficiency 73c with defective neutrophil chemotaxis and hypogammaglobulinemiaEnrichmentRAC22.59
46Hemifacial myohyperplasiaEnrichmentPIK3CA2.59
47Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowthEnrichmentPIK3CA2.59
48Immunodeficiency 36 with lymphoproliferationEnrichmentPIK3R12.59
49Autoinflammation, antibody deficiency, and immune dysregulationEnrichmentPLCG22.59
50Agammaglobulinemia 7, autosomal recessiveEnrichmentPIK3R12.59
51Immunodeficiency 97 with autoinflammationEnrichmentPIK3CG2.59
52Familial cold autoinflammatory syndrome 3EnrichmentPLCG22.59
53Immunodeficiency 22EnrichmentLCK2.59
54Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomaliesEnrichmentRHOA2.59
55Takenouchi-kosaki syndromeEnrichmentCDC422.59
56Autoinflammatory disease, systemic, with vasculitisEnrichmentLYN2.59
57Thrombocytopenia, anemia, and myelofibrosisEnrichmentMPIG6B2.59
58Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomaliesEnrichmentRHOA2.59
59Immunodeficiency 73b with defective neutrophil chemotaxis and lymphopeniaEnrichmentRAC22.59
60Segmental progressive overgrowth syndrome with fibroadipose hyperplasiaEnrichmentPIK3CA2.59
61Asphyxia neonatorumEnrichmentCOL1A12.59
62HypospadiasEnrichmentPIK3CA2.59
63ColitisEnrichmentSYK2.59
64Rare venous malformationEnrichmentPIK3CA2.59
65Vegetative pyoderma gangrenosumEnrichmentPTPN62.59
66Bullous pyoderma gangrenosumEnrichmentPTPN62.59
67Diaphragmatic eventrationEnrichmentPIK3CA2.59
68Infantile lad-like disease due to rac2 deficiencyEnrichmentRAC22.59
69Pustular pyoderma gangrenosumEnrichmentPTPN62.59
70Reticular dysgenesis-like severe combined immunodeficiencyEnrichmentRAC22.59
71Nocarh syndromeEnrichmentCDC422.59
72Pik3ca-related overgrowth spectrumEnrichmentPIK3CA2.59
73Rare combined vascular malformationEnrichmentPIK3CA2.59
74Cavernous lymphangiomaEnrichmentPIK3CA2.59
75Pik3ca-related overgrowth syndromeEnrichmentPIK3CA2.59
76Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndromEnrichmentRAC12.59
77Classic pyoderma gangrenosumEnrichmentPTPN62.59
78Hemihyperplasia-multiple lipomatosis syndromeEnrichmentPIK3CA2.59
79Eccrine angiomatous hamartomaEnrichmentPIK3CA2.59
80Rac2-related combined immunodeficiency-bronchiectasis-cancer-predisposing syndromeEnrichmentRAC22.59
81Macrodactyly of toeEnrichmentPIK3CA2.59
82Malignant astrocytomaEnrichmentPTPN112.59
83Granulomatous disease, chronic, autosomal recessive, 4EnrichmentCYBA2.53
84Systemic lupus erythematosus 6EnrichmentITGAM2.53
85Immunodeficiency 34EnrichmentCYBB2.53
86Neurodevelopmental disorder with structural brain anomalies and dysmorphic faciesEnrichmentRAC32.53
87C1q deficiency 3EnrichmentC1QC2.53
88Immunodeficiency 71 with inflammatory disease and congenital thrombocytopeniaEnrichmentARPC1B2.53
89Oculoskeletodental syndromeEnrichmentPIK3C2A2.53
90Alzheimer disease 17EnrichmentTREM22.53
91Immunodeficiency 14b, autosomal recessiveEnrichmentPIK3CD2.53
92Polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy 2EnrichmentTREM22.53
93Autoinflammation with pulmonary and cutaneous vasculitisEnrichmentHCK2.53
94C1q deficiency 2EnrichmentC1QB2.53
95Oculocerebrodental syndromeEnrichmentPIK3C2A2.53
96Epiphyseal dysplasia, multiple, 1EnrichmentCOL1A12.29
97Bruck syndrome 1EnrichmentCOL1A22.29
98Dermatofibrosarcoma protuberansEnrichmentCOL1A12.29
99Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy 2EnrichmentPIK3R52.29
100Keratosis, seborrheicEnrichmentPIK3CA2.29
101Noonan syndrome 8EnrichmentPIK3CA2.29
102Combined osteogenesis imperfecta and ehlers-danlos syndrome 1EnrichmentCOL1A12.29
103Intellectual developmental disorder, autosomal dominant 48EnrichmentRAC12.29
104Werner syndromeEnrichmentPTPN112.29
105Rosette-forming glioneuronal tumorEnrichmentPIK3CA2.29
106Stickler syndrome, type iiEnrichmentCOL1A12.29
107Immune system diseaseEnrichmentCDC422.29
108Immunodeficiency 52EnrichmentLAT2.29
109ArthritisEnrichmentSYK2.29
110Dentinogenesis imperfectaEnrichmentCOL1A22.29
111Leukocyte adhesion deficiency, type iEnrichmentITGB22.23
112Granulomatous disease, chronic, autosomal recessive, 1EnrichmentNCF12.23
113Granulomatous disease, chronic, autosomal recessive, 3EnrichmentNCF42.23
114Leukocyte adhesion deficiency, type iiiEnrichmentITGB22.23
115Roifman-chitayat syndromeEnrichmentPIK3CD2.23
116Immunodeficiency 72 with autoinflammation and lymphoproliferationEnrichmentNCKAP1L2.23
117Immunodeficiency 72EnrichmentNCKAP1L2.23
118Pompe disease, infantile-onsetEnrichmentPIK3CA2.11
119Caffey diseaseEnrichmentCOL1A12.11
120Neutrophilic dermatosis, acute febrileEnrichmentPTPN62.11
121Tricuspid valve insufficiencyEnrichmentPTPN112.11
122KeratoacanthomaEnrichmentPIK3CA2.11
123HypertelorismEnrichmentCOL1A1, PIK3CA2.10
124Autoimmune polyendocrine syndrome, type i, with or without reversible metaphyseal dysplasiaEnrichmentCYBA2.05
125Autoimmune polyendocrine syndrome type 1EnrichmentCYBA2.05
126PhenylketonuriaEnrichmentCOL1A11.99
127Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1EnrichmentPIK3R21.99
128Cerebrovascular diseaseEnrichmentPIK3CA1.99
129Noonan syndrome with multiple lentiginesEnrichmentPTPN111.99
130Familial cerebral cavernous malformationsEnrichmentPIK3CA1.99
131Capillary malformations, congenitalEnrichmentPIK3CA1.89
132LymphomaEnrichmentPTPN111.89
133HemimegalencephalyEnrichmentPIK3CA1.89
134Systemic lupus erythematosus 16EnrichmentC1QA1.83
135Klippel-trenaunay-weber syndromeEnrichmentPIK3CA1.81
136Cowden syndrome 1EnrichmentPIK3CA1.81
137KeratoconusEnrichmentCOL1A11.81
138Patent ductus arteriosusEnrichmentPTPN111.81
139Breast adenocarcinomaEnrichmentPIK3CA1.81
140Lung squamous cell carcinomaEnrichmentPIK3CA1.81
141Nevus, epidermalEnrichmentPIK3CA1.75
142Capillary malformation-arteriovenous malformation 1EnrichmentPIK3CA1.75
143Noonan syndrome 3EnrichmentPTPN111.75
144Gallbladder cancerEnrichmentPIK3CA1.75
145Overgrowth syndromeEnrichmentPIK3R11.75
146Semantic dementiaEnrichmentTREM21.69
147Early-onset autosomal dominant alzheimer diseaseEnrichmentTREM21.69
148Colorectal cancerEnrichmentPIK3CA, PIK3R11.68
149Neurodevelopmental disorder with dysmorphic facies and distal limb anomaliesEnrichmentRAC11.64
150Arteriovenous malformationEnrichmentPIK3CA1.64
151Adult hepatocellular carcinomaEnrichmentPIK3CA1.64
152Cowden syndromeEnrichmentPIK3CA1.64
153Myopathy, x-linked, with excessive autophagyEnrichmentPIK3CA1.59
154Cardiomyopathy, familial hypertrophic, 4EnrichmentNCF11.58
155Progressive non-fluent aphasiaEnrichmentTREM21.58
156Behavioral variant of frontotemporal dementiaEnrichmentTREM21.58
157Pectus excavatumEnrichmentPTPN111.55
158Immune deficiency diseaseEnrichmentSYK1.55
159Lung non-small cell carcinomaEnrichmentPIK3CA1.55
160Specific learning disabilityEnrichmentPTPN111.55
161EpicanthusEnrichmentPTPN111.52
162Juvenile myelomonocytic leukemiaEnrichmentPTPN111.52
163MeningiomaEnrichmentPIK3CA1.52
164Lip and oral cavity carcinomaEnrichmentPIK3CA1.52
165Congenital long qt syndromeEnrichmentPTPN111.52
166Frontotemporal dementia 1EnrichmentTREM21.50
167Combined immunodeficiencyEnrichmentARPC1B1.50
168Combined t cell and b cell immunodeficiencyEnrichmentARPC1B1.50
169Combined t and b cell immunodeficiencyEnrichmentARPC1B1.50
170Nk-cell enteropathyEnrichmentPIK3CB1.48
171Lynch syndromeEnrichmentPIK3CA1.42
172Noonan syndrome and noonan-related syndromeEnrichmentPTPN111.42
173Patent foramen ovaleEnrichmentPTPN111.34
174Endometrial cancerEnrichmentPIK3CA1.28
175Hepatocellular carcinomaEnrichmentPIK3CA1.26
176Williams-beuren syndromeEnrichmentNCF11.24
177Noonan syndrome 1EnrichmentPTPN111.24
178ScoliosisEnrichmentPTPN111.22
179Hydrops fetalis, nonimmuneEnrichmentPTPN111.19
180RasopathyEnrichmentPTPN111.19
181StrabismusEnrichmentPTPN111.17
182Bladder cancerEnrichmentPIK3CA1.14
183Prostate cancerEnrichmentPIK3CA1.14
184Long qt syndrome 1EnrichmentPTPN111.13
185Non-immune hydrops fetalisEnrichmentPTPN111.11
186Lung cancerEnrichmentPIK3CA1.10
187Severe combined immunodeficiencyEnrichmentLCK1.09
188Gastric cancerEnrichmentPIK3CA0.98
189Hypertrophic cardiomyopathyEnrichmentPTPN110.98
190Familial thoracic aortic aneurysm and aortic dissectionEnrichmentCOL1A10.97
191Hereditary breast carcinomaEnrichmentPIK3CA0.97
192Systemic lupus erythematosusEnrichmentITGAM0.96
193ThrombocytopeniaEnrichmentPTPN110.93
194Myeloma, multipleEnrichmentPIK3R20.87
195Male infertility with azoospermia or oligozoospermia due to single gene mutationEnrichmentPTPN110.87
196Frontotemporal dementia and/or amyotrophic lateral sclerosis 7EnrichmentTREM20.80
197Breast cancerEnrichmentPIK3CA0.75
198Ovarian cancerEnrichmentPIK3CA0.64
199Autism spectrum disorderEnrichmentPTPN110.61
200MicrocephalyEnrichmentPTPN110.56
201Inherited cancer-predisposing syndromeEnrichmentPTPN110.54
202Complex neurodevelopmental disorderEnrichmentRAC30.51

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