MicroRNAs in cardiomyocyte hypertrophy

No Pathway Network information available for MicroRNAs in cardiomyocyte hypertrophy

Pathways in the MicroRNAs in cardiomyocyte hypertrophy SuperPath

#	Name	Source	Genes
1	MicroRNAs in cardiomyocyte hypertrophy	WikiPathways	AGT AKT1 AKT2 CAMK2D CDK7 CDK9 CHUK CISH CTF1 CTNNB1 DVL1 EDN1 EGF EIF2B5 FGF2 FGFR2 FZD1 FZD2 GATA4 GSK3B HDAC4 HDAC5 HDAC7 HDAC9 IGF1 IGF1R IKBKB IKBKE IKBKG IL6ST LIF LRP5 LRP6 MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K14 MAPK1 MAPK14 MAPK3 MAPK4 MAPK7 MAPK8 MIR103A1 MIR103A2 MIR125B1 MIR125B2 MIR130B MIR133A1 MIR133A2 MIR133B MIR140 MIR15B MIR185 MIR195 MIR199A1 MIR199A2 MIR208A MIR21 MIR214 MIR23A MIR27B MIR30E MIRLET7B MTOR MYEF2 MYLK MYLK3 NFATC4 NFKB1 NPPA NPPB NRG1 PDPK1 PIK3CA PIK3CB PIK3CD PIK3CG PIK3R1 PIK3R2 PIK3R3 PLA2G2A PLCB2 PPP3CA PPP3CB PRKCB PRKG1 RAC1 RAF1 RCAN1 RHOA ROCK1 ROCK2 STAT3 TAB1 TGFB1 TNF WNT3A WNT5A (see all 103) (see less)
2	Cardiac hypertrophic response	WikiPathways	AKT1 AKT2 CALM1 CAMK2D CDK7 CDK9 CHUK GSK3B GUCA1A HDAC4 HDAC5 HDAC7 HDAC9 IKBKB IKBKE IKBKG MAP2K1 MAP2K2 MAP2K3 MAP2K4 MAP2K5 MAP2K6 MAP2K7 MAP3K1 MAP3K14 MAP3K7 MAP4K1 MAPK1 MAPK14 MAPK3 MAPK7 MAPK8 MEF2A MTOR NFATC2 NFKB1 PDPK1 PLA2G2A PPP3CA PRKCA PRKD1 PRKG1 RAC1 RAF1 (see all 44) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	HDAC7	Histone Deacetylase 7	Protein Coding	2
2	HDAC4	Histone Deacetylase 4	Protein Coding	2
3	HDAC9	Histone Deacetylase 9	Protein Coding	2
4	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	2
5	CAMK2D	Calcium/Calmodulin Dependent Protein Kinase II Delta	Protein Coding	2
6	RAF1	Raf-1 Proto-Oncogene, Serine/Threonine Kinase	Protein Coding	2
7	RAC1	Rac Family Small GTPase 1	Protein Coding	2
8	MAP2K7	Mitogen-Activated Protein Kinase Kinase 7	Protein Coding	2
9	MAP2K6	Mitogen-Activated Protein Kinase Kinase 6	Protein Coding	2
10	MAP2K5	Mitogen-Activated Protein Kinase Kinase 5	Protein Coding	2
11	MAP2K3	Mitogen-Activated Protein Kinase Kinase 3	Protein Coding	2
12	MAP2K2	Mitogen-Activated Protein Kinase Kinase 2	Protein Coding	2
13	MAP2K1	Mitogen-Activated Protein Kinase Kinase 1	Protein Coding	2
14	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	2
15	MAPK7	Mitogen-Activated Protein Kinase 7	Protein Coding	2
16	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	2
17	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	2
18	PRKG1	Protein Kinase CGMP-Dependent 1	Protein Coding	2
19	PPP3CA	Protein Phosphatase 3 Catalytic Subunit Alpha	Protein Coding	2
20	PLA2G2A	Phospholipase A2 Group IIA	Protein Coding	2
21	PDPK1	3-Phosphoinositide Dependent Protein Kinase 1	Protein Coding	2
22	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	2
23	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	2
24	GSK3B	Glycogen Synthase Kinase 3 Beta	Protein Coding	2
25	MTOR	Mechanistic Target Of Rapamycin Kinase	Protein Coding	2
26	AKT2	AKT Serine/Threonine Kinase 2	Protein Coding	2
27	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	2
28	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	2
29	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	2
30	CDK9	Cyclin Dependent Kinase 9	Protein Coding	2
31	HDAC5	Histone Deacetylase 5	Protein Coding	2
32	MAP3K14	Mitogen-Activated Protein Kinase Kinase Kinase 14	Protein Coding	2
33	CDK7	Cyclin Dependent Kinase 7	Protein Coding	2
34	MAP2K4	Mitogen-Activated Protein Kinase Kinase 4	Protein Coding	2
35	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	2
36	PLCB2	Phospholipase C Beta 2	Protein Coding	1
37	ROCK2	Rho Associated Coiled-Coil Containing Protein Kinase 2	Protein Coding	1
38	WNT3A	Wnt Family Member 3A	Protein Coding	1
39	EIF2B5	Eukaryotic Translation Initiation Factor 2B Subunit Epsilon	Protein Coding	1
40	WNT5A	Wnt Family Member 5A	Protein Coding	1
41	TNF	Tumor Necrosis Factor	Protein Coding	1
42	TGFB1	Transforming Growth Factor Beta 1	Protein Coding	1
43	STAT3	Signal Transducer And Activator Of Transcription 3	Protein Coding	1
44	ROCK1	Rho Associated Coiled-Coil Containing Protein Kinase 1	Protein Coding	1
45	PRKCB	Protein Kinase C Beta	Protein Coding	1
46	PPP3CB	Protein Phosphatase 3 Catalytic Subunit Beta	Protein Coding	1
47	PIK3R2	Phosphoinositide-3-Kinase Regulatory Subunit 2	Protein Coding	1
48	PIK3R1	Phosphoinositide-3-Kinase Regulatory Subunit 1	Protein Coding	1
49	PIK3CG	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Gamma	Protein Coding	1
50	PIK3CD	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Delta	Protein Coding	1
51	PIK3CB	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Beta	Protein Coding	1
52	PIK3CA	Phosphatidylinositol-4,5-Bisphosphate 3-Kinase Catalytic Subunit Alpha	Protein Coding	1
53	NPPB	Natriuretic Peptide B	Protein Coding	1
54	NPPA	Natriuretic Peptide A	Protein Coding	1
55	NFATC4	Nuclear Factor Of Activated T Cells 4	Protein Coding	1
56	MYLK	Myosin Light Chain Kinase	Protein Coding	1
57	MIR30E	MicroRNA 30e	RNA Gene	1
58	MIR27B	MicroRNA 27b	RNA Gene	1
59	MIR23A	MicroRNA 23a	RNA Gene	1
60	MIR214	MicroRNA 214	RNA Gene	1
61	MIR21	MicroRNA 21	RNA Gene	1
62	MIR208A	MicroRNA 208a	RNA Gene	1
63	MIR199A2	MicroRNA 199a-2	RNA Gene	1
64	MIR195	MicroRNA 195	RNA Gene	1
65	MIR185	MicroRNA 185	RNA Gene	1
66	MIR15B	MicroRNA 15b	RNA Gene	1
67	MIR140	MicroRNA 140	RNA Gene	1
68	MIR133A2	MicroRNA 133a-2	RNA Gene	1
69	MIR133A1	MicroRNA 133a-1	RNA Gene	1
70	MIR130B	MicroRNA 130b	RNA Gene	1
71	MIR125B2	MicroRNA 125b-2	RNA Gene	1
72	MIR125B1	MicroRNA 125b-1	RNA Gene	1
73	MIRLET7B	MicroRNA Let-7b	RNA Gene	1
74	LRP5	LDL Receptor Related Protein 5	Protein Coding	1
75	LRP6	LDL Receptor Related Protein 6	Protein Coding	1
76	LIF	LIF Interleukin 6 Family Cytokine	Protein Coding	1
77	RHOA	Ras Homolog Family Member A	Protein Coding	1
78	IL6ST	Interleukin 6 Cytokine Family Signal Transducer	Protein Coding	1
79	IGF1R	Insulin Like Growth Factor 1 Receptor	Protein Coding	1
80	IGF1	Insulin Like Growth Factor 1	Protein Coding	1
81	NRG1	Neuregulin 1	Protein Coding	1
82	GATA4	GATA Binding Protein 4	Protein Coding	1
83	FZD2	Frizzled Class Receptor 2	Protein Coding	1
84	FGFR2	Fibroblast Growth Factor Receptor 2	Protein Coding	1
85	FGF2	Fibroblast Growth Factor 2	Protein Coding	1
86	EGF	Epidermal Growth Factor	Protein Coding	1
87	EDN1	Endothelin 1	Protein Coding	1
88	DVL1	Dishevelled Segment Polarity Protein 1	Protein Coding	1
89	AGT	Angiotensinogen	Protein Coding	1
90	RCAN1	Regulator Of Calcineurin 1	Protein Coding	1
91	CTNNB1	Catenin Beta 1	Protein Coding	1
92	CTF1	Cardiotrophin 1	Protein Coding	1
93	CISH	Cytokine Inducible SH2 Containing Protein	Protein Coding	1
94	TAB1	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1	Protein Coding	1
95	PIK3R3	Phosphoinositide-3-Kinase Regulatory Subunit 3	Protein Coding	1
96	FZD1	Frizzled Class Receptor 1	Protein Coding	1
97	MAPK4	Mitogen-Activated Protein Kinase 4	Protein Coding	1
98	MYEF2	Myelin Expression Factor 2	Protein Coding	1
99	MIR133B	MicroRNA 133b	RNA Gene	1
100	MIR199A1	MicroRNA 199a-1	RNA Gene	1
101	MIR103A2	MicroRNA 103a-2	RNA Gene	1
102	MIR103A1	MicroRNA 103a-1	RNA Gene	1
103	MYLK3	Myosin Light Chain Kinase 3	Protein Coding	1
104	CALM1	Calmodulin 1	Protein Coding	1
105	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
106	PRKD1	Protein Kinase D1	Protein Coding	1
107	PRKCA	Protein Kinase C Alpha	Protein Coding	1
108	NFATC2	Nuclear Factor Of Activated T Cells 2	Protein Coding	1
109	MAP3K1	Mitogen-Activated Protein Kinase Kinase Kinase 1	Protein Coding	1
110	MEF2A	Myocyte Enhancer Factor 2A	Protein Coding	1
111	GUCA1A	Guanylate Cyclase Activator 1A	Protein Coding	1
112	MAP4K1	Mitogen-Activated Protein Kinase Kinase Kinase Kinase 1	Protein Coding	1

Disorders associated with MicroRNAs in cardiomyocyte hypertrophy SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Robinow syndrome, autosomal dominant 1	Enrichment	DVL1, FZD2, WNT5A	5.77
2	Autosomal dominant robinow syndrome	Enrichment	DVL1, FZD2, WNT5A	5.77
3	Robinow syndrome, autosomal recessive 1	Enrichment	DVL1, FZD2, WNT5A	5.38
4	Autosomal recessive robinow syndrome	Enrichment	DVL1, FZD2, WNT5A	5.08
5	Noonan syndrome and noonan-related syndrome	Enrichment	MAP2K1, MAP2K2, RAF1	4.85
6	Adult hepatocellular carcinoma	Enrichment	CTNNB1, EGF, PIK3CA	4.46
7	Colorectal cancer	Enrichment	AKT1, CTNNB1, FGFR2, PIK3CA, PIK3R1, PLA2G2A	4.29
8	Noonan syndrome 1	Enrichment	MAP2K1, MAP2K2, RAF1	4.27
9	Cardiofaciocutaneous syndrome 1	Enrichment	MAP2K1, MAP2K2	4.21
10	Cardiofaciocutaneous syndrome	Enrichment	MAP2K1, MAP2K2	4.21
11	Rasopathy	Enrichment	MAP2K1, MAP2K2, RAF1	4.10
12	Congenital lipomatous overgrowth, vascular malformations, and epidermal nevi	Enrichment	PIK3CA, PIK3R1	3.77
13	Immunodeficiency 14a with lymphoproliferation, autosomal dominant	Enrichment	PIK3CD, PIK3R1	3.77
14	Immunodeficiency 14	Enrichment	PIK3CD, PIK3R1	3.77
15	Polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	3.57
16	Autosomal dominant polycystic liver disease	Enrichment	CTNNB1, LRP5, LRP6	3.57
17	Megalencephaly-capillary malformation-polymicrogyria syndrome	Enrichment	PIK3CA, PIK3R2	3.47
18	Exudative vitreoretinopathy 1	Enrichment	CTNNB1, LRP5	3.25
19	Insulin-like growth factor i	Enrichment	IGF1, IGF1R	3.25
20	Robinow syndrome, autosomal dominant 2	Enrichment	DVL1, FZD2	3.25
21	Hemimegalencephaly	Enrichment	MTOR, PIK3CA	3.25
22	Malaria	Enrichment	CISH, IKBKG, TNF	3.17
23	Hemihyperplasia, isolated	Enrichment	PIK3CA, RHOA	3.08
24	Breast adenocarcinoma	Enrichment	AKT1, PIK3CA	3.08
25	Capillary malformation-arteriovenous malformation 1	Enrichment	MAP2K1, PIK3CA	2.93
26	Gallbladder cancer	Enrichment	CTNNB1, PIK3CA	2.93
27	Overgrowth syndrome	Enrichment	MTOR, PIK3R1	2.93
28	Exudative vitreoretinopathy	Enrichment	CTNNB1, LRP5	2.81
29	Arteriovenous malformation	Enrichment	MAP2K1, PIK3CA	2.70
30	Cowden syndrome	Enrichment	AKT1, PIK3CA	2.70
31	Myopathy, x-linked, with excessive autophagy	Enrichment	MAP2K1, PIK3CA	2.61
32	Autosomal non-syndromic agammaglobulinemia	Enrichment	PIK3CD, PIK3R1	2.61
33	Lung non-small cell carcinoma	Enrichment	MAP2K1, PIK3CA	2.52
34	Proteus syndrome	Enrichment	AKT1	2.49
35	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	2.49
36	Hypoinsulinemic hypoglycemia with hemihypertrophy	Enrichment	AKT2	2.49
37	Incontinentia pigmenti	Enrichment	IKBKG	2.49
38	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	2.49
39	Noonan syndrome 5	Enrichment	RAF1	2.49
40	Melorheostosis, isolated	Enrichment	MAP2K1	2.49
41	Cardiomyopathy, dilated, 1nn	Enrichment	RAF1	2.49
42	Cardiofaciocutaneous syndrome 3	Enrichment	MAP2K1	2.49
43	Fetal encasement syndrome	Enrichment	CHUK	2.49
44	Aortic aneurysm, familial thoracic 8	Enrichment	PRKG1	2.49
45	46,xy sex reversal 6	Enrichment	MAP3K1	2.49
46	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	2.49
47	Immunodeficiency 15b	Enrichment	IKBKB	2.49
48	Noonan syndrome 13	Enrichment	MAPK1	2.49
49	Immunodeficiency 15a	Enrichment	IKBKB	2.49
50	Chromosome 2q37 deletion syndrome	Enrichment	HDAC4	2.49
51	Auriculocondylar syndrome 4	Enrichment	HDAC9	2.49
52	Developmental and epileptic encephalopathy 91	Enrichment	PPP3CA	2.49
53	Arthrogryposis, cleft palate, craniosynostosis, and impaired intellectual development	Enrichment	PPP3CA	2.49
54	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	2.49
55	Coronary artery disease, autosomal dominant, 1	Enrichment	MEF2A	2.49
56	Melorheostosis	Enrichment	MAP2K1	2.49
57	Leopard syndrome 2	Enrichment	RAF1	2.49
58	Cardiofaciocutaneous syndrome 4	Enrichment	MAP2K2	2.49
59	Cowden syndrome 6	Enrichment	AKT1	2.49
60	Congenital heart defects and ectodermal dysplasia	Enrichment	PRKD1	2.49
61	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.49
62	Neurodevelopmental disorder with central hypotonia and dysmorphic facies	Enrichment	HDAC4	2.49
63	Trigonitis	Enrichment	RAF1	2.49
64	Immunodeficiency 112	Enrichment	MAP3K14	2.49
65	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.49
66	Microcephaly-corpus callosum and cerebellar vermis hypoplasia-facial dysmorphism-intellectual disability syndrom	Enrichment	RAC1	2.49
67	Malignant epithelial tumor of salivary glands	Enrichment	PRKD1	2.49
68	Nik deficiency	Enrichment	MAP3K14	2.49
69	Akt2-related familial partial lipodystrophy	Enrichment	AKT2	2.49
70	Meningioma	Enrichment	AKT1, PIK3CA	2.45
71	Nk-cell enteropathy	Enrichment	IGF1R, PIK3CB	2.37
72	Aortic aneurysm, familial thoracic 1	Enrichment	GATA4, MYLK	2.31
73	Scoliosis, isolated 1	Enrichment	MAPK7	2.19
74	Immunodeficiency 33	Enrichment	IKBKG	2.19
75	Ventricular tachycardia, catecholaminergic polymorphic, 4	Enrichment	CALM1	2.19
76	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.19
77	Long qt syndrome 14	Enrichment	CALM1	2.19
78	Intellectual developmental disorder, autosomal dominant 48	Enrichment	RAC1	2.19
79	Cebalid syndrome	Enrichment	MTOR	2.19
80	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG	2.19
81	Cone-rod dystrophy 14	Enrichment	GUCA1A	2.19
82	Smith-kingsmore syndrome	Enrichment	MTOR	2.19
83	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	2.19
84	Joint contractures, osteochondromas, and b-cell lymphoma	Enrichment	NFATC2	2.19
85	Common variable immunodeficiency 12	Enrichment	NFKB1	2.19
86	Tafro syndrome	Enrichment	MAP2K2	2.19
87	Macrodactyly	Enrichment	PIK3CA	2.12
88	Beare-stevenson cutis gyrata syndrome	Enrichment	FGFR2	2.12
89	Endosteal hyperostosis, autosomal dominant	Enrichment	LRP5	2.12
90	Bone mineral density quantitative trait locus 1	Enrichment	LRP5	2.12
91	Exudative vitreoretinopathy 4	Enrichment	LRP5	2.12
92	Hypomagnesemia 4, renal	Enrichment	EGF	2.12
93	Scaphocephaly, maxillary retrusion, and impaired intellectual development	Enrichment	FGFR2	2.12
94	Megalencephaly, autosomal dominant	Enrichment	PIK3CA	2.12
95	Omodysplasia 2	Enrichment	FZD2	2.12
96	Apert syndrome	Enrichment	FGFR2	2.12
97	Cowden syndrome 5	Enrichment	PIK3CA	2.12
98	Tooth agenesis, selective, 7	Enrichment	LRP6	2.12
99	Atrioventricular septal defect 4	Enrichment	GATA4	2.12
100	Bent bone dysplasia syndrome 1	Enrichment	FGFR2	2.12
101	Exudative vitreoretinopathy 8	Enrichment	LRP6	2.12
102	Cerebral cavernous malformations 4	Enrichment	PIK3CA	2.12
103	Auriculocondylar syndrome 3	Enrichment	EDN1	2.12
104	Stuve-wiedemann syndrome 2	Enrichment	IL6ST	2.12
105	Hyper-ige syndrome 4a, autosomal dominant, with recurrent infections	Enrichment	IL6ST	2.12
106	Short syndrome	Enrichment	PIK3R1	2.12
107	T-cell large granular lymphocyte leukemia	Enrichment	STAT3	2.12
108	Osteoporosis-pseudoglioma syndrome	Enrichment	LRP5	2.12
109	Coronary artery disease, autosomal dominant 2	Enrichment	LRP6	2.12
110	Hemifacial myohyperplasia	Enrichment	PIK3CA	2.12
111	Question mark ears, isolated	Enrichment	EDN1	2.12
112	Capillary malformation of the lower lip, lymphatic malformation of face and neck, asymmetry of face and limbs, and partial/generalized overgrowth	Enrichment	PIK3CA	2.12
113	Polycystic liver disease 4 with or without kidney cysts	Enrichment	LRP5	2.12
114	Atrial septal defect 2	Enrichment	GATA4	2.12
115	Immunodeficiency 36 with lymphoproliferation	Enrichment	PIK3R1	2.12
116	Testicular anomalies with or without congenital heart disease	Enrichment	GATA4	2.12
117	Immunodeficiency 14b, autosomal recessive	Enrichment	PIK3CD	2.12
118	Agammaglobulinemia 7, autosomal recessive	Enrichment	PIK3R1	2.12
119	Immunodeficiency 97 with autoinflammation	Enrichment	PIK3CG	2.12
120	Autoimmune disease, multisystem, infantile-onset, 1	Enrichment	STAT3	2.12
121	Hyper-ige syndrome 4b, autosomal recessive, with recurrent infections	Enrichment	IL6ST	2.12
122	8p23.1 microdeletion syndrome	Enrichment	GATA4	2.12
123	Ectodermal dysplasia with facial dysmorphism and acral, ocular, and brain anomalies	Enrichment	RHOA	2.12
124	Immunodeficiency 94 with autoinflammation and dysmorphic facies	Enrichment	IL6ST	2.12
125	Linear hypopigmentation and craniofacial asymmetry with acral, ocular and brain anomalies	Enrichment	RHOA	2.12
126	Segmental progressive overgrowth syndrome with fibroadipose hyperplasia	Enrichment	PIK3CA	2.12
127	Adenoid ameloblastoma	Enrichment	CTNNB1	2.12
128	Hypospadias	Enrichment	PIK3CA	2.12
129	Lrp5-related primary osteoporosis	Enrichment	LRP5	2.12
130	Stat3-related early-onset multisystem autoimmune disease	Enrichment	STAT3	2.12
131	Rare venous malformation	Enrichment	PIK3CA	2.12
132	Diaphragmatic eventration	Enrichment	PIK3CA	2.12
133	Pik3ca-related overgrowth spectrum	Enrichment	PIK3CA	2.12
134	Partial atrioventricular septal defect with ventricular hypoplasia	Enrichment	GATA4	2.12
135	Rare combined vascular malformation	Enrichment	PIK3CA	2.12
136	Cavernous lymphangioma	Enrichment	PIK3CA	2.12
137	Pik3ca-related overgrowth syndrome	Enrichment	PIK3CA	2.12
138	Osteosclerosis-developmental delay-craniosynostosis syndrome	Enrichment	LRP5	2.12
139	Hemihyperplasia-multiple lipomatosis syndrome	Enrichment	PIK3CA	2.12
140	Chronic lymphoproliferative disorder of natural killer cells	Enrichment	STAT3	2.12
141	Eccrine angiomatous hamartoma	Enrichment	PIK3CA	2.12
142	Egf-related primary hypomagnesemia with intellectual disability	Enrichment	EGF	2.12
143	Non-syndromic unicoronal craniosynostosis	Enrichment	FGFR2	2.12
144	Macrodactyly of toe	Enrichment	PIK3CA	2.12
145	Microcystic stromal tumor	Enrichment	CTNNB1	2.12
146	Heart, malformation of	Enrichment	GATA4, MAPK1	2.09
147	Cone dystrophy 3	Enrichment	GUCA1A	2.01
148	Langerhans cell histiocytosis	Enrichment	MAP2K1	2.01
149	Frontometaphyseal dysplasia	Enrichment	MAP3K7	2.01
150	Endometrial cancer	Enrichment	FGFR2, PIK3CA	1.96
151	Hepatocellular carcinoma	Enrichment	CTNNB1, PIK3CA	1.92
152	Neurofibromatosis-noonan syndrome	Enrichment	MAP2K2	1.89
153	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	1.89
154	Focal cortical dysplasia, type ii	Enrichment	MTOR	1.89
155	Noonan syndrome with multiple lentigines	Enrichment	RAF1	1.89
156	Isolated focal cortical dysplasia type ii	Enrichment	MTOR	1.89
157	Familial atrial fibrillation	Enrichment	GATA4, NPPA	1.85
158	Camurati-engelmann disease 1	Enrichment	TGFB1	1.82
159	Van buchem disease	Enrichment	LRP5	1.82
160	Osteopathia striata with cranial sclerosis	Enrichment	CTNNB1	1.82
161	Aural atresia, congenital	Enrichment	FGFR2	1.82
162	Keratosis, seborrheic	Enrichment	PIK3CA	1.82
163	Pfeiffer syndrome	Enrichment	FGFR2	1.82
164	Albinism, oculocutaneous, type vi	Enrichment	MYEF2	1.82
165	Jackson-weiss syndrome	Enrichment	FGFR2	1.82
166	Roifman-chitayat syndrome	Enrichment	PIK3CD	1.82
167	Atrial fibrillation, familial, 6	Enrichment	NPPA	1.82
168	Robinow syndrome, autosomal dominant 3	Enrichment	FZD2	1.82
169	Noonan syndrome 8	Enrichment	PIK3CA	1.82
170	Antley-bixler syndrome without genital anomalies or disordered steroidogenesis	Enrichment	FGFR2	1.82
171	Spondyloepiphyseal dysplasia, nishimura type	Enrichment	MIR140	1.82
172	Inflammatory bowel disease, immunodeficiency, and encephalopathy	Enrichment	TGFB1	1.82
173	Immunodeficiency 127	Enrichment	TNF	1.82
174	Childhood hepatocellular carcinoma	Enrichment	CTNNB1	1.82
175	Split hand-foot malformation	Enrichment	FGFR2	1.82
176	Rosette-forming glioneuronal tumor	Enrichment	PIK3CA	1.82
177	Camurati-engelmann disease	Enrichment	TGFB1	1.82
178	46,xy sex reversal 3	Enrichment	GATA4	1.82
179	Immune system disease	Enrichment	PIK3CD	1.82
180	Juvenile nasopharyngeal angiofibroma	Enrichment	CTNNB1	1.82
181	Autosomal dominant nonsyndromic deafness	Enrichment	FGFR2	1.82
182	Growth delay due to insulin-like growth factor type 1 deficiency	Enrichment	IGF1	1.82
183	Isolated atrial standstill	Enrichment	NPPA	1.82
184	Teratoma	Enrichment	CTNNB1	1.82
185	Osteosclerosis	Enrichment	LRP5	1.82
186	Choroidal dystrophy, central areolar, 1	Enrichment	GUCA1A	1.79
187	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.79
188	Ventricular tachycardia, catecholaminergic polymorphic, 1, with or without atrial dysfunction and/or dilated cardiomyopathy	Enrichment	CALM1	1.71
189	Bladder cancer	Enrichment	CTNNB1, PIK3CA	1.69
190	Renal cell carcinoma, papillary, 1	Enrichment	MTOR	1.65
191	Noonan syndrome 3	Enrichment	RAF1	1.65
192	Pilomyxoid astrocytoma	Enrichment	RAF1	1.65
193	Common variable immunodeficiency	Enrichment	NFKB1	1.65
194	Crouzon syndrome	Enrichment	FGFR2	1.65
195	Desmoid disease, hereditary	Enrichment	CTNNB1	1.65
196	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	STAT3	1.65
197	Lacrimoauriculodentodigital syndrome 1	Enrichment	FGFR2	1.65
198	Pompe disease, infantile-onset	Enrichment	PIK3CA	1.65
199	Stuve-wiedemann syndrome 1	Enrichment	IL6ST	1.65
200	Osteopetrosis, autosomal dominant 1	Enrichment	LRP5	1.65
201	Osteoporosis, juvenile	Enrichment	WNT3A	1.65
202	Psoriatic arthritis	Enrichment	TNF	1.65
203	Neurodevelopmental disorder with spastic diplegia and visual defects	Enrichment	CTNNB1	1.65
204	Aortic aneurysm, familial thoracic 7	Enrichment	MYLK	1.65
205	Atrial standstill 2	Enrichment	NPPA	1.65
206	Anus, imperforate	Enrichment	CTNNB1	1.65
207	Exudative vitreoretinopathy 7	Enrichment	CTNNB1	1.65
208	Bacteremia 2	Enrichment	CISH	1.65
209	Breast implant-associated anaplastic large cell lymphoma	Enrichment	STAT3	1.65
210	Desmoid tumor	Enrichment	CTNNB1	1.65
211	Hyper ige syndrome	Enrichment	STAT3	1.65
212	Migraine without aura	Enrichment	TNF	1.65
213	Growth delay due to insulin-like growth factor i resistance	Enrichment	IGF1R	1.65
214	Stüve-wiedemann syndrome	Enrichment	IL6ST	1.65
215	Keratoacanthoma	Enrichment	PIK3CA	1.65
216	Melanocytic nevus syndrome, congenital	Enrichment	RAF1	1.59
217	Catecholaminergic polymorphic ventricular tachycardia 1	Enrichment	CALM1	1.59
218	Catecholaminergic polymorphic ventricular tachycardia	Enrichment	CALM1	1.59
219	Coronary heart disease 5	Enrichment	IKBKG	1.54
220	Neurodevelopmental disorder with dysmorphic facies and distal limb anomalies	Enrichment	RAC1	1.54
221	Neurodegeneration with brain iron accumulation 1	Enrichment	MIR103A2	1.52
222	Megacystis-microcolon-intestinal hypoperistalsis syndrome 1	Enrichment	MYLK	1.52
223	Auriculocondylar syndrome 1	Enrichment	EDN1	1.52
224	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	PIK3R2	1.52
225	Saethre-chotzen syndrome	Enrichment	FGFR2	1.52
226	Pilomatrixoma	Enrichment	CTNNB1	1.52
227	Alazami syndrome	Enrichment	CTNNB1	1.52
228	Orofacial cleft	Enrichment	LRP6	1.52
229	Retinopathy of prematurity	Enrichment	LRP5	1.52
230	Cerebrovascular disease	Enrichment	PIK3CA	1.52
231	Craniopharyngioma	Enrichment	CTNNB1	1.52
232	Tuberculosis	Enrichment	CISH	1.52
233	Familial cerebral cavernous malformations	Enrichment	PIK3CA	1.52
234	Cerebral malaria	Enrichment	TNF	1.52
235	Transposition of the great arteries	Enrichment	GATA4	1.52
236	Glioma	Enrichment	FGFR2	1.52
237	Vitreoretinopathy	Enrichment	LRP5	1.52
238	Orofacial clefting syndrome	Enrichment	LRP6	1.52
239	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.50
240	Familial colorectal cancer	Enrichment	PLA2G2A	1.50
241	46,xy complete gonadal dysgenesis	Enrichment	MAP3K1	1.45
242	Specific learning disability	Enrichment	MAPK1	1.45
243	Hemifacial hyperplasia	Enrichment	FGFR2	1.43
244	Capillary malformations, congenital	Enrichment	PIK3CA	1.43
245	Visceral myopathy 1	Enrichment	MYLK	1.43
246	Ventricular septal defect 1	Enrichment	GATA4	1.43
247	Congenital heart defects, multiple types, 4	Enrichment	GATA4	1.43
248	Vascular dementia	Enrichment	TNF	1.43
249	Ovarian cancer	Enrichment	AKT1, CTNNB1, PIK3CA	1.38
250	Gastric cancer	Enrichment	FGFR2, PIK3CA	1.38
251	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	MYLK, PRKG1	1.36
252	Hereditary breast carcinoma	Enrichment	AKT1, PIK3CA	1.36
253	Cone-rod dystrophy 6	Enrichment	GUCA1A	1.35
254	46,xy partial gonadal dysgenesis	Enrichment	MAP3K1	1.35
255	Isolated macular dystrophy	Enrichment	GUCA1A	1.35
256	Klippel-trenaunay-weber syndrome	Enrichment	PIK3CA	1.35
257	Cowden syndrome 1	Enrichment	PIK3CA	1.35
258	Weyers acrofacial dysostosis	Enrichment	CTNNB1	1.35
259	Split-hand/foot malformation 1	Enrichment	FGFR2	1.35
260	Renal tubular dysgenesis	Enrichment	AGT	1.35
261	Inflammatory bowel disease 25, autosomal recessive	Enrichment	TGFB1	1.35
262	Adrenocortical carcinoma	Enrichment	CTNNB1	1.35
263	Il10-related early-onset inflammatory bowel disease	Enrichment	TGFB1	1.35
264	Lung squamous cell carcinoma	Enrichment	PIK3CA	1.35
265	Renal cell carcinoma, nonpapillary	Enrichment	MTOR	1.32
266	Rare genetic intellectual disability	Enrichment	MTOR	1.32
267	Nevus, epidermal	Enrichment	PIK3CA	1.28
268	Leukoencephalopathy with vanishing white matter 1	Enrichment	EIF2B5	1.28
269	Oculocutaneous albinism	Enrichment	MYEF2	1.28
270	Leukoencephalopathy with vanishing white matter 5	Enrichment	EIF2B5	1.23
271	Permanent neonatal diabetes mellitus	Enrichment	STAT3	1.23
272	Hypertelorism	Enrichment	FGFR2, PIK3CA	1.23
273	Cardiomyopathy, dilated, 1a	Enrichment	NFATC2	1.18
274	Leukoencephalopathy with vanishing white matter	Enrichment	EIF2B5	1.18
275	Familial thoracic aortic aneurysm and dissection	Enrichment	MYLK	1.18
276	Microcephaly	Enrichment	CTNNB1, IGF1R, MAPK1	1.17
277	Myeloma, multiple	Enrichment	HDAC4, PIK3R2	1.17
278	Meier-gorlin syndrome 1	Enrichment	FGFR2	1.13
279	Cardiomyopathy, familial hypertrophic, 1	Enrichment	RAF1	1.12
280	Asthma	Enrichment	TNF	1.09
281	Lip and oral cavity carcinoma	Enrichment	PIK3CA	1.06
282	Long qt syndrome 1	Enrichment	CALM1	1.03
283	Acute promyelocytic leukemia	Enrichment	STAT3	1.03
284	Alzheimer's disease	Enrichment	TNF	1.03
285	Long qt syndrome	Enrichment	CALM1	1.02
286	Osteoporosis	Enrichment	LRP5	0.99
287	Medulloblastoma	Enrichment	CTNNB1	0.99
288	Heart disease	Enrichment	GATA4	0.99
289	Usher syndrome	Enrichment	GUCA1A	0.99
290	Familial hypertrophic cardiomyopathy	Enrichment	RAF1	0.99
291	Severe combined immunodeficiency	Enrichment	IKBKB	0.99
292	Left ventricular noncompaction	Enrichment	RAF1	0.97
293	Hydrocephalus	Enrichment	FGFR2	0.97
294	Lynch syndrome	Enrichment	PIK3CA	0.97
295	Breast cancer	Enrichment	AKT1, PIK3CA	0.95
296	Hypertension, essential	Enrichment	AGT	0.92
297	Type 2 diabetes mellitus	Enrichment	AKT2	0.89
298	Patent foramen ovale	Enrichment	GATA4	0.89
299	Diffuse large b-cell lymphoma	Enrichment	STAT3	0.87
300	Craniosynostosis	Enrichment	FGFR2	0.85
301	Hepatoblastoma	Enrichment	CTNNB1	0.83
302	Autosomal dominant non-syndromic intellectual disability	Enrichment	PPP3CA	0.82
303	Tooth agenesis	Enrichment	LRP6	0.81
304	Familial isolated dilated cardiomyopathy	Enrichment	RAF1	0.80
305	Brittle bone disorder	Enrichment	LRP5	0.79
306	Undetermined early-onset epileptic encephalopathy	Enrichment	PPP3CA	0.78
307	Tetralogy of fallot	Enrichment	GATA4	0.74
308	Prostate cancer	Enrichment	PIK3CA	0.70
309	Cone-rod dystrophy 2	Enrichment	GUCA1A	0.70
310	Lung cancer	Enrichment	PIK3CA	0.66
311	Cystic fibrosis	Enrichment	TGFB1	0.66
312	Dilated cardiomyopathy	Enrichment	RAF1	0.64
313	Systemic lupus erythematosus	Enrichment	TNF	0.59
314	Autism spectrum disorder	Enrichment	MAP2K1	0.52
315	Hereditary breast ovarian cancer syndrome	Enrichment	EIF2B5	0.46
316	Male infertility with azoospermia or oligozoospermia due to single gene mutation	Enrichment	GATA4	0.46
317	Retinitis pigmentosa	Enrichment	GUCA1A	0.30
318	Congenital nervous system abnormality	Enrichment	CTNNB1	0.26
319	Nervous system disease	Enrichment	CTNNB1	0.26
320	Hereditary retinal dystrophy	Enrichment	GUCA1A	0.21
321	Fundus dystrophy	Enrichment	GUCA1A	0.21

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

MicroRNAs in cardiomyocyte hypertrophy

Pathway Network for MicroRNAs in cardiomyocyte hypertrophy

Member Pathways for MicroRNAs in cardiomyocyte hypertrophy

Pathways in the MicroRNAs in cardiomyocyte hypertrophy SuperPath

Associated Genes for MicroRNAs in cardiomyocyte hypertrophy

Associated Disorders for MicroRNAs in cardiomyocyte hypertrophy

Disorders associated with MicroRNAs in cardiomyocyte hypertrophy SuperPath

STRING Interaction Network for MicroRNAs in cardiomyocyte hypertrophy

Sources for MicroRNAs in cardiomyocyte hypertrophy