MIF Action Through Endocytic Pathway

No Pathway Network information available for MIF Action Through Endocytic Pathway

#	Name	Source	Genes
1	MIF Action Through Endocytic Pathway	QIAGEN	CD14 CDKN1B COPS5 ETS1 ETS2 FOS JUN LY96 MAPK1 MAPK3 MIF TLR4 (see all 12) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CD14	CD14 Molecule	Protein Coding	1
2	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
3	COPS5	COP9 Signalosome Subunit 5	Protein Coding	1
4	ETS1	ETS Proto-Oncogene 1, Transcription Factor	Protein Coding	1
5	ETS2	ETS Proto-Oncogene 2, Transcription Factor	Protein Coding	1
6	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
7	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
8	LY96	Lymphocyte Antigen 96	Protein Coding	1
9	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
10	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
11	MIF	Macrophage Migration Inhibitory Factor	Protein Coding	1
12	TLR4	Toll Like Receptor 4	Protein Coding	1

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 13	Enrichment	MAPK1	3.05
2	Neuroendocrine tumor	Enrichment	CDKN1B	3.05
3	Macular degeneration, age-related, 10	Enrichment	TLR4	3.05
4	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	2.75
5	Jacobsen syndrome	Enrichment	ETS1	2.58
6	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.45
7	Congenital generalized lipodystrophy	Enrichment	FOS	2.45
8	Primary hyperparathyroidism	Enrichment	CDKN1B	2.45
9	Systemic-onset juvenile idiopathic arthritis	Enrichment	MIF	2.45
10	Rheumatoid arthritis, systemic juvenile	Enrichment	MIF	2.35
11	Histiocytoid hemangioma	Enrichment	FOS	2.35
12	Multiple endocrine neoplasia, type i	Enrichment	CDKN1B	2.21
13	Specific learning disability	Enrichment	MAPK1	2.01
14	Heart, malformation of	Enrichment	MAPK1	1.80
15	Behcet syndrome	Enrichment	TLR4	1.78
16	Cystic fibrosis	Enrichment	MIF	1.55
17	Systemic lupus erythematosus	Enrichment	ETS1	1.47
18	Breast cancer	Enrichment	JUN	1.19
19	Ovarian cancer	Enrichment	CDKN1B	1.07
20	Microcephaly	Enrichment	MAPK1	0.98
21	Inherited cancer-predisposing syndrome	Enrichment	CDKN1B	0.96

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Pathway Network for MIF Action Through Endocytic Pathway