miR-509-3p alteration of YAP1/ECM axis

No Pathway Network information available for miR-509-3p alteration of YAP1/ECM axis

Pathways in the miR-509-3p alteration of YAP1/ECM axis SuperPath

#	Name	Source	Genes
1	miR-509-3p alteration of YAP1/ECM axis	WikiPathways	BCAR1 COL1A1 COL3A1 COL5A1 EDNRA FN1 GPC6 PBX3 SNAI2 SPARC TEAD1 TEAD2 TEAD3 TEAD4 THBS2 TWIST1 YAP1 (see all 17) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	BCAR1	BCAR1 Scaffold Protein, Cas Family Member	Protein Coding	1
2	TEAD2	TEA Domain Transcription Factor 2	Protein Coding	1
3	TWIST1	Twist Family BHLH Transcription Factor 1	Protein Coding	1
4	THBS2	Thrombospondin 2	Protein Coding	1
5	TEAD1	TEA Domain Transcription Factor 1	Protein Coding	1
6	SPARC	Secreted Protein Acidic And Cysteine Rich	Protein Coding	1
7	SNAI2	Snail Family Transcriptional Repressor 2	Protein Coding	1
8	FN1	Fibronectin 1	Protein Coding	1
9	EDNRA	Endothelin Receptor Type A	Protein Coding	1
10	COL5A1	Collagen Type V Alpha 1 Chain	Protein Coding	1
11	COL3A1	Collagen Type III Alpha 1 Chain	Protein Coding	1
12	COL1A1	Collagen Type I Alpha 1 Chain	Protein Coding	1
13	YAP1	Yes1 Associated Transcriptional Regulator	Protein Coding	1
14	GPC6	Glypican 6	Protein Coding	1
15	TEAD3	TEA Domain Transcription Factor 3	Protein Coding	1
16	TEAD4	TEA Domain Transcription Factor 4	Protein Coding	1
17	PBX3	PBX Homeobox 3	Protein Coding	1

Disorders associated with miR-509-3p alteration of YAP1/ECM axis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ehlers-danlos syndrome	Enrichment	COL1A1, COL3A1, COL5A1, THBS2	8.19
2	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL1A1, COL3A1, COL5A1	4.68
3	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A1, COL5A1	4.66
4	Classic ehlers-danlos syndrome	Enrichment	COL1A1, COL5A1	4.66
5	Osteogenesis imperfecta, type iv	Enrichment	COL1A1, SPARC	3.94
6	Coloboma, ocular, with or without hearing impairment, cleft lip/palate, and/or impaired intellectual development	Enrichment	YAP1	2.90
7	Mandibulofacial dysostosis with alopecia	Enrichment	EDNRA	2.90
8	Acrogeria, gottron type	Enrichment	COL3A1	2.90
9	Uveal coloboma-cleft lip and palate-intellectual disability	Enrichment	YAP1	2.90
10	Asphyxia neonatorum	Enrichment	COL1A1	2.90
11	Pneumothorax	Enrichment	COL5A1	2.90
12	Abdominal aortic aneurysm	Enrichment	COL3A1	2.90
13	Ehlers-danlos syndrome, vascular type	Enrichment	COL3A1	2.60
14	Epiphyseal dysplasia, multiple, 1	Enrichment	COL1A1	2.60
15	Ehlers-danlos syndrome, hypermobility type	Enrichment	COL3A1	2.60
16	Sveinsson chorioretinal atrophy	Enrichment	TEAD1	2.60
17	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	2.60
18	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	2.60
19	Robinow-sorauf syndrome	Enrichment	TWIST1	2.60
20	Omodysplasia 1	Enrichment	GPC6	2.60
21	Dermatofibrosarcoma protuberans	Enrichment	COL1A1	2.60
22	Piebald trait	Enrichment	SNAI2	2.60
23	Combined osteogenesis imperfecta and ehlers-danlos syndrome 1	Enrichment	COL1A1	2.60
24	Fibromuscular dysplasia, multifocal	Enrichment	COL5A1	2.60
25	Sweeney-cox syndrome	Enrichment	TWIST1	2.60
26	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A1	2.60
27	Polymicrogyria with or without vascular-type ehlers-danlos syndrome	Enrichment	COL3A1	2.60
28	Retinitis pigmentosa 14	Enrichment	TEAD3	2.60
29	Aortic dissection	Enrichment	COL3A1	2.60
30	Osteogenesis imperfecta, type xvii	Enrichment	SPARC	2.60
31	Stickler syndrome, type ii	Enrichment	COL1A1	2.60
32	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A1	2.60
33	Non-syndromic sagittal craniosynostosis	Enrichment	TWIST1	2.60
34	Craniosynostosis 1	Enrichment	TWIST1	2.43
35	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.43
36	Ehlers-danlos syndrome, classic type, 2	Enrichment	COL5A1	2.43
37	Caffey disease	Enrichment	COL1A1	2.43
38	Ehlers-danlos syndrome, classic-like, 3	Enrichment	THBS2	2.43
39	High bone mass osteogenesis imperfecta	Enrichment	COL1A1	2.43
40	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A1	2.30
41	Phenylketonuria	Enrichment	COL1A1	2.30
42	Saethre-chotzen syndrome	Enrichment	TWIST1	2.30
43	Malignant epithelioid hemangioendothelioma	Enrichment	YAP1	2.30
44	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A1	2.30
45	Non-syndromic bicoronal craniosynostosis	Enrichment	TWIST1	2.30
46	Familial cerebral saccular aneurysm	Enrichment	COL3A1	2.20
47	Osteogenesis imperfecta, type i	Enrichment	COL1A1	2.13
48	Inguinal hernia	Enrichment	COL5A1	2.13
49	Keratoconus	Enrichment	COL1A1	2.13
50	Pain disorder	Enrichment	COL5A1	2.13
51	Osteogenesis imperfecta, type ii	Enrichment	COL1A1	2.06
52	Intervertebral disc disease	Enrichment	THBS2	2.06
53	Waardenburg syndrome, type 2e	Enrichment	SNAI2	2.06
54	Gastroesophageal reflux	Enrichment	COL5A1	2.00
55	Spastic paraplegia 4, autosomal dominant	Enrichment	COL3A1	2.00
56	Orthostatic intolerance	Enrichment	COL5A1	2.00
57	Familial thoracic aortic aneurysm and dissection	Enrichment	COL3A1	1.95
58	Primary bone dysplasia	Enrichment	COL1A1	1.90
59	Osteochondrodysplasia	Enrichment	COL1A1	1.86
60	Cutis laxa	Enrichment	COL5A1	1.83
61	Microphthalmia/coloboma 12	Enrichment	YAP1	1.79
62	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	COL5A1	1.79
63	Clubfoot	Enrichment	COL5A1	1.79
64	Osteoporosis	Enrichment	COL1A1	1.76
65	Aortic aneurysm, familial thoracic 1	Enrichment	COL3A1	1.76
66	Cataract	Enrichment	COL5A1	1.76
67	Coloboma of macula	Enrichment	YAP1	1.73
68	Osteogenesis imperfecta, type iii	Enrichment	COL1A1	1.73
69	Brittle bone disorder	Enrichment	COL1A1	1.55
70	Cystic fibrosis	Enrichment	EDNRA	1.40
71	Connective tissue disease	Enrichment	COL5A1	1.40
72	Nephrotic syndrome	Enrichment	FN1	1.28
73	Hypertelorism	Enrichment	COL1A1	1.20
74	Hereditary breast ovarian cancer syndrome	Enrichment	BCAR1	1.18
75	Myeloma, multiple	Enrichment	YAP1	1.17
76	Leber plus disease	Enrichment	TEAD3	0.95
77	Hereditary retinal dystrophy	Enrichment	TEAD3	0.51
78	Fundus dystrophy	Enrichment	TEAD3	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

miR-509-3p alteration of YAP1/ECM axis

Pathway Network for miR-509-3p alteration of YAP1/ECM axis

Member Pathways for miR-509-3p alteration of YAP1/ECM axis

Pathways in the miR-509-3p alteration of YAP1/ECM axis SuperPath

Associated Genes for miR-509-3p alteration of YAP1/ECM axis

Associated Disorders for miR-509-3p alteration of YAP1/ECM axis

Disorders associated with miR-509-3p alteration of YAP1/ECM axis SuperPath

STRING Interaction Network for miR-509-3p alteration of YAP1/ECM axis

Sources for miR-509-3p alteration of YAP1/ECM axis