miRNA regulation of DNA damage response

No Pathway Network information available for miRNA regulation of DNA damage response

Pathways in the miRNA regulation of DNA damage response SuperPath

#	Name	Source	Genes
1	miRNA regulation of DNA damage response	WikiPathways	ABL1 APAF1 ATM ATR ATRIP BAX BBC3 BID BRCA1 CASP3 CASP8 CASP9 CCNB1 CCNB2 CCNB3 CCND1 CCND2 CCND3 CCNE1 CCNE2 CCNG1 CDC25A CDC25C CDK1 CDK2 CDK4 CDK5 CDK6 CDKN1A CDKN1B CHEK1 CHEK2 CREB1 CYCS DDB2 E2F1 FANCD2 FAS GADD45A GADD45B GADD45G H2AX HUS1B MDM2 MIR145 MIR15A MIR20A MIR24-1 MRE11 MYC NBN PIDD1 PMAIP1 PML PRKDC RAD1 RAD17 RAD50 RAD51 RAD52 RAD9A RB1 RFC1 RPA2 RRM2B SESN1 SFN SMC1A TLK1 TLK2 TNFRSF10B TP53 TP53AIP1 (see all 73) (see less)
2	DNA damage response	WikiPathways	ABL1 AKT1 APAF1 ATM ATR ATRIP BAX BBC3 BID BRCA1 CASP3 CASP8 CASP9 CCNB1 CCNB2 CCNB3 CCND1 CCND2 CCND3 CCNE1 CCNE2 CDC25A CDC25C CDK1 CDK2 CDK4 CDK5 CDK6 CDKN1A CDKN1B CHEK1 CHEK2 CREB1 CYCS DDB2 E2F1 FANCD2 FAS GADD45A GADD45B GADD45G H2AX HUS1B MDM2 MRE11 MYC NBN PIDD1 PMAIP1 PML PRKDC RAD1 RAD17 RAD50 RAD51 RAD52 RAD9A RB1 RFC1 RPA2 RRM2B SESN1 SFN SMC1A TLK1 TLK2 TNFRSF10B TP53 TP53AIP1 (see all 69) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CDC25C	Cell Division Cycle 25C	Protein Coding	2
2	TLK1	Tousled Like Kinase 1	Protein Coding	2
3	CDK1	Cyclin Dependent Kinase 1	Protein Coding	2
4	CCNE2	Cyclin E2	Protein Coding	2
5	CCNB2	Cyclin B2	Protein Coding	2
6	CCNE1	Cyclin E1	Protein Coding	2
7	CCND3	Cyclin D3	Protein Coding	2
8	CCND2	Cyclin D2	Protein Coding	2
9	CCNB1	Cyclin B1	Protein Coding	2
10	TNFRSF10B	TNF Receptor Superfamily Member 10b	Protein Coding	2
11	CCNB3	Cyclin B3	Protein Coding	2
12	CASP9	Caspase 9	Protein Coding	2
13	CASP8	Caspase 8	Protein Coding	2
14	CASP3	Caspase 3	Protein Coding	2
15	SMC1A	Structural Maintenance Of Chromosomes 1A	Protein Coding	2
16	TP53	Tumor Protein P53	Protein Coding	2
17	BRCA1	BRCA1 DNA Repair Associated	Protein Coding	2
18	BID	BH3 Interacting Domain Death Agonist	Protein Coding	2
19	RFC1	Replication Factor C Subunit 1	Protein Coding	2
20	CCND1	Cyclin D1	Protein Coding	2
21	RB1	RB Transcriptional Corepressor 1	Protein Coding	2
22	RAD52	RAD52 DNA Repair Protein	Protein Coding	2
23	RAD51	RAD51 Recombinase	Protein Coding	2
24	RAD9A	RAD9 Checkpoint Clamp Component A	Protein Coding	2
25	BAX	BCL2 Associated X, Apoptosis Regulator	Protein Coding	2
26	PRKDC	Protein Kinase, DNA-Activated, Catalytic Subunit	Protein Coding	2
27	PIDD1	P53-Induced Death Domain Protein 1	Protein Coding	2
28	ATR	ATR Checkpoint Kinase	Protein Coding	2
29	CYCS	Cytochrome C, Somatic	Protein Coding	2
30	PML	PML Nuclear Body Scaffold	Protein Coding	2
31	PMAIP1	Phorbol-12-Myristate-13-Acetate-Induced Protein 1	Protein Coding	2
32	RRM2B	Ribonucleotide Reductase Regulatory TP53 Inducible Subunit M2B	Protein Coding	2
33	ATM	ATM Serine/Threonine Kinase	Protein Coding	2
34	NBN	Nibrin	Protein Coding	2
35	GADD45B	Growth Arrest And DNA Damage Inducible Beta	Protein Coding	2
36	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	2
37	MRE11	MRE11 Double Strand Break Repair Nuclease	Protein Coding	2
38	MDM2	MDM2 Proto-Oncogene	Protein Coding	2
39	FAS	Fas Cell Surface Death Receptor	Protein Coding	2
40	APAF1	Apoptotic Peptidase Activating Factor 1	Protein Coding	2
41	H2AX	H2A.X Variant Histone	Protein Coding	2
42	SFN	Stratifin	Protein Coding	2
43	BBC3	BCL2 Binding Component 3	Protein Coding	2
44	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	2
45	FANCD2	FA Complementation Group D2	Protein Coding	2
46	E2F1	E2F Transcription Factor 1	Protein Coding	2
47	GADD45A	Growth Arrest And DNA Damage Inducible Alpha	Protein Coding	2
48	DDB2	Damage Specific DNA Binding Protein 2	Protein Coding	2
49	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	2
50	CHEK2	Checkpoint Kinase 2	Protein Coding	2
51	CHEK1	Checkpoint Kinase 1	Protein Coding	2
52	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	2
53	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	2
54	CDK6	Cyclin Dependent Kinase 6	Protein Coding	2
55	CDK5	Cyclin Dependent Kinase 5	Protein Coding	2
56	CDK4	Cyclin Dependent Kinase 4	Protein Coding	2
57	CDK2	Cyclin Dependent Kinase 2	Protein Coding	2
58	RAD50	RAD50 Double Strand Break Repair Protein	Protein Coding	2
59	ATRIP	ATR Interacting Protein	Protein Coding	2
60	HUS1B	HUS1 Checkpoint Clamp Component B	Protein Coding	2
61	TLK2	Tousled Like Kinase 2	Protein Coding	2
62	GADD45G	Growth Arrest And DNA Damage Inducible Gamma	Protein Coding	2
63	TP53AIP1	Tumor Protein P53 Regulated Apoptosis Inducing Protein 1	Protein Coding	2
64	RPA2	Replication Protein A2	Protein Coding	2
65	RAD17	RAD17 Checkpoint Clamp Loader Component	Protein Coding	2
66	RAD1	RAD1 Checkpoint DNA Exonuclease	Protein Coding	2
67	CDC25A	Cell Division Cycle 25A	Protein Coding	2
68	SESN1	Sestrin 1	Protein Coding	2
69	CCNG1	Cyclin G1	Protein Coding	1
70	MIR24-1	MicroRNA 24-1	RNA Gene	1
71	MIR20A	MicroRNA 20a	RNA Gene	1
72	MIR15A	MicroRNA 15a	RNA Gene	1
73	MIR145	MicroRNA 145	RNA Gene	1
74	AKT1	AKT Serine/Threonine Kinase 1	Protein Coding	1

Disorders associated with miRNA regulation of DNA damage response SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Breast cancer	Enrichment	AKT1, ATM, BRCA1, CASP8, CHEK2, MRE11, NBN, RAD50, RAD51, TP53	16.00
2	Ovarian cancer	Enrichment	AKT1, ATM, BRCA1, CDKN1B, CHEK2, FANCD2, MRE11, NBN, RAD50, RB1, TP53	16.00
3	Hereditary breast carcinoma	Enrichment	AKT1, ATM, BRCA1, CHEK2, NBN, RAD50, RAD51, TP53	10.58
4	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, BRCA1, CHEK2, MRE11, NBN, RAD50, RAD51, TP53	9.52
5	Inherited cancer-predisposing syndrome	Enrichment	ATM, BRCA1, CDK4, CDKN1B, CHEK2, MRE11, NBN, RAD50, RB1, TP53	8.95
6	Gastric cancer	Enrichment	ATM, BRCA1, CDK4, CHEK2, NBN, TP53	7.14
7	Osteogenic sarcoma	Enrichment	CHEK2, RB1, TP53	6.90
8	Bone osteosarcoma	Enrichment	CHEK2, RB1, TP53	6.90
9	Pancreatic cancer	Enrichment	ATM, BRCA1, CHEK2, NBN, TP53	6.84
10	Colorectal cancer	Enrichment	AKT1, ATM, BAX, BRCA1, CCND1, CHEK2, TP53	6.56
11	Bladder cancer	Enrichment	ATM, BRCA1, CDKN1A, RB1, TP53	6.50
12	Prostate cancer	Enrichment	ATM, BRCA1, CHEK2, NBN, TP53	6.50
13	Breast-ovarian cancer, familial 1	Enrichment	ATM, BRCA1, CHEK2, NBN	6.37
14	Li-fraumeni syndrome	Enrichment	CHEK2, MDM2, TP53	5.60
15	Hepatocellular carcinoma	Enrichment	CASP8, NBN, RAD50, TP53	5.38
16	Colonic benign neoplasm	Enrichment	ATM, CHEK2, MRE11	4.98
17	Leukemia, chronic lymphocytic	Enrichment	ATM, CCND1, TP53	4.83
18	Lung cancer	Enrichment	BRCA1, CASP8, CHEK2, FAS	4.70
19	Uterine corpus cancer	Enrichment	ATM, BRCA1, CHEK2	4.69
20	Li-fraumeni syndrome 1	Enrichment	CHEK2, TP53	4.59
21	Sarcoma	Enrichment	CHEK2, TP53	4.59
22	Lip and oral cavity carcinoma	Enrichment	ABL1, RB1, TP53	4.57
23	Dedifferentiated liposarcoma	Enrichment	CDK4, MDM2	4.12
24	Squamous cell carcinoma	Enrichment	RB1, TP53	4.12
25	T-cell acute lymphoblastic leukemia	Enrichment	ABL1, BAX	4.12
26	Adenocarcinoma	Enrichment	ATM, TP53	4.12
27	Well-differentiated liposarcoma	Enrichment	CDK4, MDM2	4.12
28	Diffuse large b-cell lymphoma	Enrichment	CHEK2, NBN, TP53	3.94
29	Small cell cancer of the lung	Enrichment	RB1, TP53	3.82
30	Mantle cell lymphoma	Enrichment	ATM, CCND1	3.82
31	Nijmegen breakage syndrome-like disorder	Enrichment	MRE11, RAD50	3.82
32	Endometrial cancer	Enrichment	ATM, BRCA1, CHEK2	3.80
33	Von hippel-lindau syndrome	Enrichment	CCND1, FANCD2	3.60
34	Breast adenocarcinoma	Enrichment	AKT1, TP53	3.42
35	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	3.28
36	Squamous cell carcinoma, head and neck	Enrichment	TNFRSF10B, TP53	3.28
37	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, TP53	3.28
38	Fanconi anemia, complementation group a	Enrichment	BRCA1, FANCD2, RAD51	3.13
39	Adult hepatocellular carcinoma	Enrichment	CASP8, TP53	3.05
40	Lynch syndrome 1	Enrichment	ATM, CHEK2	2.95
41	Familial colorectal cancer type x	Enrichment	ATM, CHEK2	2.87
42	Lung cancer susceptibility 3	Enrichment	RB1, TP53	2.65
43	Seckel syndrome	Enrichment	ATR, ATRIP	2.65
44	Myeloma, multiple	Enrichment	ATM, CCND1, TP53	2.54
45	Rhabdomyosarcoma	Enrichment	BRCA1, TP53	2.53
46	Gliosarcoma	Enrichment	ATM, TP53	2.53
47	Giant cell glioblastoma	Enrichment	ATM, TP53	2.48
48	Palmoplantar keratoderma, punctate type ii	Enrichment	BRCA1	2.29
49	Proteus syndrome	Enrichment	AKT1	2.29
50	Developmental and epileptic encephalopathy 85 with or without midline brain defects	Enrichment	SMC1A	2.29
51	Caspase 8 deficiency	Enrichment	CASP8	2.29
52	Melanoma, cutaneous malignant 3	Enrichment	CDK4	2.29
53	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 3	Enrichment	CCND2	2.29
54	Seckel syndrome 1	Enrichment	ATR	2.29
55	Microcephaly 12, primary, autosomal recessive	Enrichment	CDK6	2.29
56	Mirror movements 2	Enrichment	RAD51	2.29
57	Accelerated tumor formation	Enrichment	MDM2	2.29
58	Lissencephaly 7 with cerebellar hypoplasia	Enrichment	CDK5	2.29
59	Fanconi anemia, complementation group r	Enrichment	RAD51	2.29
60	Lessel-kubisch syndrome	Enrichment	MDM2	2.29
61	Bone marrow failure syndrome 5	Enrichment	TP53	2.29
62	Papilloma of choroid plexus	Enrichment	TP53	2.29
63	Basal cell carcinoma 7	Enrichment	TP53	2.29
64	Anaplastic thyroid carcinoma	Enrichment	TP53	2.29
65	Infant-type hemispheric glioma	Enrichment	BRCA1	2.29
66	Mitochondrial dna depletion syndrome 8b	Enrichment	RRM2B	2.29
67	Tumor predisposition syndrome 4	Enrichment	CHEK2	2.29
68	Thrombocytopenia 4	Enrichment	CYCS	2.29
69	Ataxia-telangiectasia-like disorder 1	Enrichment	MRE11	2.29
70	Neuroendocrine tumor	Enrichment	CDKN1B	2.29
71	Cutaneous telangiectasia and cancer syndrome, familial	Enrichment	ATR	2.29
72	Immunodeficiency 26 with or without neurologic abnormalities	Enrichment	PRKDC	2.29
73	Cowden syndrome 6	Enrichment	AKT1	2.29
74	Endometrial serous adenocarcinoma	Enrichment	ATM	2.29
75	Ductal carcinoma in situ	Enrichment	TP53	2.29
76	Leiomyosarcoma	Enrichment	CHEK2	2.29
77	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.29
78	Trilateral retinoblastoma	Enrichment	RB1	2.29
79	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.29
80	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.29
81	Oocyte/zygote/embryo maturation arrest 21	Enrichment	CHEK1	2.29
82	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.29
83	Choroid plexus cancer	Enrichment	TP53	2.29
84	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.29
85	Intellectual developmental disorder, autosomal recessive 75, with neuropsychiatric features and variant lissencephaly	Enrichment	PIDD1	2.29
86	Familial cutaneous telangiectasia and oropharyngeal predisposition cancer syndrome	Enrichment	ATR	2.29
87	Rrm2b mitochondrial dna maintenance defects	Enrichment	RRM2B	2.29
88	Primary peritoneal carcinoma	Enrichment	BRCA1	2.29
89	Lung oat cell carcinoma	Enrichment	RB1	2.29
90	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, MYC	2.22
91	Fanconi renotubular syndrome 1	Enrichment	RRM2B	1.99
92	Burkitt lymphoma	Enrichment	MYC	1.99
93	Adrenocortical carcinoma, hereditary	Enrichment	TP53	1.99
94	Cervical cancer	Enrichment	TP53	1.99
95	Cornelia de lange syndrome 2	Enrichment	SMC1A	1.99
96	Rod-cone dystrophy, sensorineural deafness, and fanconi-type renal dysfunction	Enrichment	RRM2B	1.99
97	Xeroderma pigmentosum, complementation group e	Enrichment	DDB2	1.99
98	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 5	Enrichment	RRM2B	1.99
99	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	1.99
100	Mitochondrial dna depletion syndrome 8a	Enrichment	RRM2B	1.99
101	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal recessive 2	Enrichment	RRM2B	1.99
102	Chromosome 13q14 deletion syndrome	Enrichment	RB1	1.99
103	Lymphoma, hodgkin, classic	Enrichment	TP53	1.99
104	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	1.99
105	Cerebellar ataxia, neuropathy, and vestibular areflexia syndrome	Enrichment	RFC1	1.99
106	Congenital heart defects, multiple types, 3	Enrichment	CHEK2	1.99
107	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	1.99
108	Fanconi anemia, complementation group s	Enrichment	BRCA1	1.99
109	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	1.99
110	Pancreatic cancer 4	Enrichment	BRCA1	1.99
111	Congenital fibrosarcoma	Enrichment	TP53	1.99
112	High grade glioma	Enrichment	ATM	1.99
113	Cervix carcinoma	Enrichment	TP53	1.99
114	Hodgkin's lymphoma	Enrichment	TP53	1.99
115	T-cell prolymphocytic leukemia	Enrichment	ATM	1.99
116	Inflammatory breast carcinoma	Enrichment	BRCA1	1.99
117	Peritoneum cancer	Enrichment	BRCA1	1.99
118	Bilateral breast cancer	Enrichment	BRCA1	1.99
119	Familial retinoblastoma	Enrichment	RB1	1.99
120	Xeroderma pigmentosum group e	Enrichment	DDB2	1.99
121	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	1.99
122	Retinoblastoma	Enrichment	RB1	1.82
123	Ataxia-telangiectasia	Enrichment	ATM	1.82
124	Vasculopathy, retinal, with cerebral leukoencephalopathy and systemic manifestations	Enrichment	ATRIP	1.82
125	Nijmegen breakage syndrome	Enrichment	NBN	1.82
126	Polycythemia vera	Enrichment	ATM	1.82
127	Chilblain lupus 1	Enrichment	ATRIP	1.82
128	Nasopharyngeal carcinoma	Enrichment	TP53	1.82
129	Woolly hair, autosomal recessive 3	Enrichment	RB1	1.82
130	Intellectual developmental disorder, autosomal dominant 57	Enrichment	TLK2	1.82
131	Hypotrichosis 8	Enrichment	RB1	1.82
132	Koolen-de vries syndrome	Enrichment	ATM	1.82
133	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.82
134	Chilblain lupus	Enrichment	ATRIP	1.82
135	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.82
136	Anaplastic astrocytoma	Enrichment	TP53	1.82
137	Laryngeal squamous cell carcinoma	Enrichment	TNFRSF10B	1.82
138	Idiopathic camptocormia	Enrichment	RRM2B	1.82
139	Melanoma of soft tissue	Enrichment	CREB1	1.82
140	Vogt-koyanagi-harada disease	Enrichment	FAS	1.82
141	Leukemia, acute myeloid	Enrichment	FANCD2, TP53	1.76
142	Mirror movements 1	Enrichment	RAD51	1.69
143	Ataxia, early-onset, with oculomotor apraxia and hypoalbuminemia	Enrichment	MRE11	1.69
144	Erythrocytosis, familial, 2	Enrichment	FANCD2	1.69
145	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.69
146	Polyposis syndrome, hereditary mixed, 1	Enrichment	BRCA1	1.69
147	Autoimmune lymphoproliferative syndrome	Enrichment	FAS	1.69
148	Megalencephaly-polymicrogyria-polydactyly-hydrocephalus syndrome 1	Enrichment	CCND2	1.69
149	Cholangiocarcinoma	Enrichment	BRCA1	1.69
150	Aicardi-goutieres syndrome 1	Enrichment	ATRIP	1.69
151	Lynch syndrome 4	Enrichment	RB1	1.69
152	Lung sarcomatoid carcinoma	Enrichment	TP53	1.69
153	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	1.69
154	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.69
155	Pregnancy loss, recurrent 1	Enrichment	CCNB3	1.69
156	Hemoglobin c disease	Enrichment	CHEK2	1.69
157	Primary hyperparathyroidism	Enrichment	CDKN1B	1.69
158	Thrombotic microangiopathy	Enrichment	ATRIP	1.69
159	Oculomotor apraxia	Enrichment	ATM	1.69
160	Male infertility due to gonadal dysgenesis or sperm disorder	Enrichment	CHEK1	1.69
161	Microcephaly	Enrichment	ABL1, NBN, SMC1A	1.61
162	Cerebral arteriopathy, autosomal dominant, with subcortical infarcts and leukoencephalopathy, type 1	Enrichment	ATRIP	1.60
163	Fanconi anemia, complementation group d2	Enrichment	FANCD2	1.60
164	Kearns-sayre syndrome	Enrichment	RRM2B	1.60
165	Rhabdomyosarcoma 2	Enrichment	TP53	1.60
166	Breast-ovarian cancer, familial 2	Enrichment	BRCA1	1.60
167	Lymphoma	Enrichment	TP53	1.60
168	Glioblastoma	Enrichment	ATM	1.60
169	Vascular dementia	Enrichment	ATRIP	1.60
170	Acute megakaryocytic leukemia	Enrichment	TP53	1.60
171	Autosomal thrombocytopenia with normal platelets	Enrichment	CYCS	1.60
172	Progressive external ophthalmoplegia with mitochondrial dna deletions, autosomal dominant 1	Enrichment	RRM2B	1.52
173	Wilms tumor 5	Enrichment	CHEK2	1.52
174	Wiedemann-steiner syndrome	Enrichment	SMC1A	1.52
175	Adrenocortical carcinoma	Enrichment	TP53	1.52
176	Clear cell renal cell carcinoma	Enrichment	ATM	1.52
177	Esophageal cancer	Enrichment	TP53	1.45
178	Leukemia, chronic myeloid	Enrichment	ABL1	1.45
179	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.45
180	Essential thrombocythemia	Enrichment	TP53	1.45
181	Gallbladder cancer	Enrichment	TP53	1.45
182	Moyamoya angiopathy	Enrichment	ABL1	1.45
183	Primary ovarian insufficiency	Enrichment	CHEK2, NBN	1.44
184	Glioma susceptibility 1	Enrichment	TP53	1.40
185	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.40
186	Rett syndrome, congenital variant	Enrichment	SMC1A	1.40
187	Cornelia de lange syndrome 1	Enrichment	SMC1A	1.35
188	Primary hyperaldosteronism	Enrichment	TP53	1.35
189	Cornelia de lange syndrome	Enrichment	SMC1A	1.35
190	Cowden syndrome	Enrichment	AKT1	1.35
191	Mitochondrial neurogastrointestinal encephalomyopathy	Enrichment	RRM2B	1.35
192	Aplastic anemia	Enrichment	NBN	1.30
193	Aicardi-goutieres syndrome	Enrichment	ATRIP	1.30
194	Melanoma	Enrichment	CHEK2	1.30
195	Familial colorectal cancer	Enrichment	TP53	1.30
196	Immune deficiency disease	Enrichment	ATM	1.26
197	Xeroderma pigmentosum, variant type	Enrichment	DDB2	1.26
198	Leukemia, acute lymphoblastic	Enrichment	NBN	1.26
199	Myelodysplastic syndrome	Enrichment	TP53	1.26
200	Meningioma	Enrichment	AKT1	1.23
201	Acute promyelocytic leukemia	Enrichment	PML	1.19
202	Premature menopause	Enrichment	NBN	1.19
203	Nk-cell enteropathy	Enrichment	CHEK2	1.19
204	Periventricular nodular heterotopia	Enrichment	BRCA1	1.16
205	Heart disease	Enrichment	ABL1	1.16
206	Renal cell carcinoma, nonpapillary	Enrichment	ATM	1.13
207	Wilms tumor 1	Enrichment	CHEK2	1.13
208	Lynch syndrome	Enrichment	CHEK2	1.13
209	Melanoma, cutaneous malignant 1	Enrichment	CDK4	1.08
210	Polycystic liver disease	Enrichment	CDC25A	1.08
211	Autosomal dominant polycystic liver disease	Enrichment	CDC25A	1.08
212	Semilobar holoprosencephaly	Enrichment	SMC1A	1.06
213	Behcet syndrome	Enrichment	FAS	1.03
214	Parkinson's disease	Enrichment	RFC1	1.03
215	Lissencephaly	Enrichment	NBN	0.99
216	Hepatoblastoma	Enrichment	TP53	0.99
217	Diamond-blackfan anemia 1	Enrichment	TP53	0.96
218	Parkinson disease, late-onset	Enrichment	RFC1	0.94
219	Primary autosomal recessive microcephaly	Enrichment	CDK6	0.82
220	Diamond-blackfan anemia	Enrichment	TP53	0.77
221	Systemic lupus erythematosus	Enrichment	ATRIP	0.74
222	Sensorineural hearing loss	Enrichment	RRM2B	0.66
223	Thrombocytopenia	Enrichment	CYCS	0.66
224	Mitochondrial disease	Enrichment	RRM2B	0.44
225	Congenital nervous system abnormality	Enrichment	SMC1A	0.38
226	Nervous system disease	Enrichment	SMC1A	0.38
227	Retinitis pigmentosa	Enrichment	RRM2B	0.18
228	Hereditary retinal dystrophy	Enrichment	ATRIP	0.11
229	Fundus dystrophy	Enrichment	ATRIP	0.11

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

miRNA regulation of DNA damage response

Pathway Network for miRNA regulation of DNA damage response

Member Pathways for miRNA regulation of DNA damage response

Pathways in the miRNA regulation of DNA damage response SuperPath

Associated Genes for miRNA regulation of DNA damage response

Associated Disorders for miRNA regulation of DNA damage response

Disorders associated with miRNA regulation of DNA damage response SuperPath

STRING Interaction Network for miRNA regulation of DNA damage response

Sources for miRNA regulation of DNA damage response