miRNA role in immune response in sepsis

No Pathway Network information available for miRNA role in immune response in sepsis

Pathways in the miRNA role in immune response in sepsis SuperPath

#	Name	Source	Genes
1	miRNA role in immune response in sepsis	WikiPathways	CCL3 CCL4 CHUK CXCL8 ELANE GZMB ICAM1 IKBKB IKBKG IL10 IL1A IL6 IRAK1 IRAK4 IRF1 IRF5 IRF7 LCN2 MAP3K7 MAPK14 MAPK8 MIR106A MIR106B MIR122 MIR125B1 MIR125B2 MIR126 MIR145 MIR146B MIR149 MIR155 MIR155HG MIR16-1 MIR16-2 MIR187 MIR199A1 MIR199A2 MIR19A MIR200B MIR200C MIR203A MIR203B MIR21 MIR223HG MIR758 MIR9-1 MIRLET7I MYD88 NFKB1 NFKB2 REL RELA RELB TAB1 TAB2 TLR4 TLR7 TLR8 TNF TRAF3 TRAF6 VCAM1 (see all 62) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	IKBKG	Inhibitor Of Nuclear Factor Kappa B Kinase Regulatory Subunit Gamma	Protein Coding	1
2	MIR758	MicroRNA 758	RNA Gene	1
3	VCAM1	Vascular Cell Adhesion Molecule 1	Protein Coding	1
4	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
5	TRAF3	TNF Receptor Associated Factor 3	Protein Coding	1
6	TNF	Tumor Necrosis Factor	Protein Coding	1
7	TLR4	Toll Like Receptor 4	Protein Coding	1
8	MAP3K7	Mitogen-Activated Protein Kinase Kinase Kinase 7	Protein Coding	1
9	CCL4	C-C Motif Chemokine Ligand 4	Protein Coding	1
10	CCL3	C-C Motif Chemokine Ligand 3	Protein Coding	1
11	RELB	RELB Proto-Oncogene, NF-KB Subunit	Protein Coding	1
12	RELA	RELA Proto-Oncogene, NF-KB Subunit	Protein Coding	1
13	REL	REL Proto-Oncogene, NF-KB Subunit	Protein Coding	1
14	MIR146B	MicroRNA 146b	RNA Gene	1
15	MAPK8	Mitogen-Activated Protein Kinase 8	Protein Coding	1
16	TLR8	Toll Like Receptor 8	Protein Coding	1
17	TLR7	Toll Like Receptor 7	Protein Coding	1
18	IRAK4	Interleukin 1 Receptor Associated Kinase 4	Protein Coding	1
19	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
20	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
21	MYD88	MYD88 Innate Immune Signal Transduction Adaptor	Protein Coding	1
22	MIR9-1	MicroRNA 9-1	RNA Gene	1
23	MIR21	MicroRNA 21	RNA Gene	1
24	MIR203A	MicroRNA 203a	RNA Gene	1
25	MIR200C	MicroRNA 200c	RNA Gene	1
26	MIR200B	MicroRNA 200b	RNA Gene	1
27	MIR19A	MicroRNA 19a	RNA Gene	1
28	MIR199A2	MicroRNA 199a-2	RNA Gene	1
29	MIR16-1	MicroRNA 16-1	RNA Gene	1
30	MIR155	MicroRNA 155	RNA Gene	1
31	MIR149	MicroRNA 149	RNA Gene	1
32	MIR145	MicroRNA 145	RNA Gene	1
33	MIR126	MicroRNA 126	RNA Gene	1
34	MIR125B2	MicroRNA 125b-2	RNA Gene	1
35	MIR125B1	MicroRNA 125b-1	RNA Gene	1
36	MIR122	MicroRNA 122	RNA Gene	1
37	MIR106B	MicroRNA 106b	RNA Gene	1
38	MIR106A	MicroRNA 106a	RNA Gene	1
39	MIRLET7I	MicroRNA Let-7i	RNA Gene	1
40	LCN2	Lipocalin 2	Protein Coding	1
41	IRF7	Interferon Regulatory Factor 7	Protein Coding	1
42	IRF5	Interferon Regulatory Factor 5	Protein Coding	1
43	IRF1	Interferon Regulatory Factor 1	Protein Coding	1
44	IRAK1	Interleukin 1 Receptor Associated Kinase 1	Protein Coding	1
45	IL10	Interleukin 10	Protein Coding	1
46	CXCL8	C-X-C Motif Chemokine Ligand 8	Protein Coding	1
47	IL6	Interleukin 6	Protein Coding	1
48	IL1A	Interleukin 1 Alpha	Protein Coding	1
49	IKBKB	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Beta	Protein Coding	1
50	ICAM1	Intercellular Adhesion Molecule 1	Protein Coding	1
51	GZMB	Granzyme B	Protein Coding	1
52	TAB2	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 2	Protein Coding	1
53	ELANE	Elastase, Neutrophil Expressed	Protein Coding	1
54	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
55	CHUK	Component Of Inhibitor Of Nuclear Factor Kappa B Kinase Complex	Protein Coding	1
56	TAB1	TGF-Beta Activated Kinase 1 (MAP3K7) Binding Protein 1	Protein Coding	1
57	MIR223HG	MIR223 Host Gene	RNA Gene	1
58	MIR155HG	MIR155 Host Gene	RNA Gene	1
59	MIR199A1	MicroRNA 199a-1	RNA Gene	1
60	MIR187	MicroRNA 187	RNA Gene	1
61	MIR16-2	MicroRNA 16-2	RNA Gene	1
62	MIR203B	MicroRNA 203b	RNA Gene	1

Disorders associated with miRNA role in immune response in sepsis SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Systemic lupus erythematosus	Enrichment	IL10, IRAK1, IRF5, TLR7, TNF	6.06
2	Immunodeficiency 33	Enrichment	IKBKG, IRAK4	4.69
3	Transient predisposition to invasive pyogenic bacterial infection	Enrichment	IRAK4, MYD88	4.69
4	Cerebral malaria	Enrichment	ICAM1, TNF	3.91
5	Malaria	Enrichment	ICAM1, IKBKG, TNF	3.82
6	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	3.37
7	Rheumatoid arthritis	Enrichment	IL10, IRF5	3.14
8	Human immunodeficiency virus type 1	Enrichment	CCL3, IL10	2.52
9	Behcet syndrome	Enrichment	IL10, TLR4	2.48
10	Cardiospondylocarpofacial syndrome	Enrichment	MAP3K7	2.34
11	Incontinentia pigmenti	Enrichment	IKBKG	2.34
12	Autoinflammatory disease, systemic, x-linked	Enrichment	IKBKG	2.34
13	Immunodeficiency 68	Enrichment	MYD88	2.34
14	Macroglobulinemia, waldenstrom 1	Enrichment	MYD88	2.34
15	Immunodeficiency 39 viral infections	Enrichment	IRF7	2.34
16	Fetal encasement syndrome	Enrichment	CHUK	2.34
17	Frontometaphyseal dysplasia 2	Enrichment	MAP3K7	2.34
18	Immunodeficiency 15b	Enrichment	IKBKB	2.34
19	Immunodeficiency 15a	Enrichment	IKBKB	2.34
20	Immunodeficiency 92	Enrichment	REL	2.34
21	Immunodeficiency 74, covid19-related, x-linked	Enrichment	TLR7	2.34
22	Ectodermal dysplasia and immunodeficiency 1	Enrichment	IKBKG	2.34
23	Graft-versus-host disease	Enrichment	IL10	2.34
24	X-linked immunodeficiency 74	Enrichment	TLR7	2.34
25	Immunodeficiency 132a	Enrichment	TRAF3	2.34
26	Immunodeficiency 132b	Enrichment	TRAF3	2.34
27	Systemic lupus erythematosus 17	Enrichment	TLR7	2.34
28	Immunodeficiency 39	Enrichment	IRF7	2.34
29	Systemic lupus erythematosus 10	Enrichment	IRF5	2.34
30	Immunodeficiency 67	Enrichment	IRAK4	2.34
31	Macular degeneration, age-related, 10	Enrichment	TLR4	2.34
32	Inflammatory bowel disease 14	Enrichment	IRF5	2.34
33	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.34
34	Immunodeficiency 53	Enrichment	RELB	2.34
35	Bartsocas-papas syndrome 2	Enrichment	CHUK	2.34
36	Waldenstram macroglobulinemia	Enrichment	MYD88	2.34
37	Combined immunodeficiency-hypogammaglobulinemia-skeletal anomalies syndrome due to ikbka deficiency	Enrichment	CHUK	2.34
38	Polyvalvular heart disease syndrome	Enrichment	TAB2	2.34
39	Cyclic neutropenia	Enrichment	ELANE	2.04
40	Neutropenia, severe congenital, x-linked	Enrichment	ELANE	2.04
41	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.04
42	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.04
43	Autoinflammatory disease, familial, behcet-like 3	Enrichment	RELA	2.04
44	Immunodeficiency 127	Enrichment	TNF	2.04
45	Rela fusion-positive ependymoma	Enrichment	RELA	2.04
46	Congenital dyserythropoietic anemia	Enrichment	IRAK4	2.04
47	Ectodermal dysplasia and immune deficiency	Enrichment	IKBKG	2.04
48	Congenital heart defects, multiple types, 2	Enrichment	TAB2	2.04
49	Glucosephosphate dehydrogenase deficiency	Enrichment	IKBKG	2.04
50	Immunodeficiency 117	Enrichment	IRF1	2.04
51	Cardiac anomalies-short stature-joint hypermobility-facial dysmorphism syndrome	Enrichment	TAB2	2.04
52	Common variable immunodeficiency 12	Enrichment	NFKB1	2.04
53	Pelvic organ prolapse	Enrichment	TAB2	1.86
54	Neutropenia, severe congenital, 1, autosomal dominant	Enrichment	ELANE	1.86
55	Immunodeficiency 98 with autoinflammation, x-linked	Enrichment	TLR8	1.86
56	Psoriatic arthritis	Enrichment	TNF	1.86
57	Frontometaphyseal dysplasia	Enrichment	MAP3K7	1.86
58	Migraine without aura	Enrichment	TNF	1.86
59	Kaposi sarcoma	Enrichment	IL6	1.74
60	Anemia, autoimmune hemolytic	Enrichment	TLR8	1.74
61	Immunodeficiency, common variable, 1	Enrichment	NFKB2	1.74
62	Pediatric systemic lupus erythematosus	Enrichment	IRAK1	1.74
63	Systemic-onset juvenile idiopathic arthritis	Enrichment	IL6	1.74
64	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	1.64
65	Anemia, congenital, nonspherocytic hemolytic, 1	Enrichment	IKBKG	1.64
66	Rheumatoid arthritis, systemic juvenile	Enrichment	IL6	1.64
67	Vascular dementia	Enrichment	TNF	1.64
68	Autosomal dominant severe congenital neutropenia	Enrichment	ELANE	1.64
69	Herpes simplex virus encephalitis	Enrichment	TRAF3	1.64
70	Diffuse cutaneous systemic sclerosis	Enrichment	IRF5	1.64
71	Type 1 diabetes mellitus	Enrichment	IL6	1.57
72	Limited scleroderma	Enrichment	IRF5	1.57
73	Il10-related early-onset inflammatory bowel disease	Enrichment	IL10	1.57
74	Neutropenia	Enrichment	ELANE	1.50
75	Inflammatory bowel disease 1	Enrichment	IL6	1.39
76	Coronary heart disease 5	Enrichment	IKBKG	1.39
77	Primary biliary cholangitis	Enrichment	IRF5	1.39
78	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.35
79	Migraine with or without aura 1	Enrichment	TAB2	1.31
80	Asthma	Enrichment	TNF	1.31
81	Lung non-small cell carcinoma	Enrichment	IRF1	1.31
82	Aortic valve disease 1	Enrichment	TAB2	1.24
83	Alzheimer's disease	Enrichment	TNF	1.24
84	Patent foramen ovale	Enrichment	TAB2	1.10
85	Arteriovenous malformations of the brain	Enrichment	IL6	1.08
86	Diffuse large b-cell lymphoma	Enrichment	MYD88	1.08
87	Multisystem inflammatory syndrome in children	Enrichment	TRAF3	1.02
88	Autoinflammatory disease	Enrichment	ELANE	0.98
89	Lung cancer	Enrichment	IRF1	0.86
90	Severe combined immunodeficiency	Enrichment	IKBKB	0.85
91	Type 2 diabetes mellitus	Enrichment	IL6	0.76
92	Gastric cancer	Enrichment	IRF1	0.75
93	Dilated cardiomyopathy	Enrichment	TAB2	0.51

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

miRNA role in immune response in sepsis

Pathway Network for miRNA role in immune response in sepsis

Member Pathways for miRNA role in immune response in sepsis

Pathways in the miRNA role in immune response in sepsis SuperPath

Associated Genes for miRNA role in immune response in sepsis

Associated Disorders for miRNA role in immune response in sepsis

Disorders associated with miRNA role in immune response in sepsis SuperPath

STRING Interaction Network for miRNA role in immune response in sepsis

Sources for miRNA role in immune response in sepsis