miRNA targets in ECM and membrane receptors

No Pathway Network information available for miRNA targets in ECM and membrane receptors

Pathways in the miRNA targets in ECM and membrane receptors SuperPath

#	Name	Source	Genes
1	miRNA targets in ECM and membrane receptors	WikiPathways	COL1A2 COL3A1 COL4A1 COL4A2 COL5A1 COL5A2 COL5A3 COL6A1 COL6A2 COL6A3 FN1 ITGA1 ITGA11 ITGB5 ITGB6 LAMA4 LAMB2 LAMC1 MIR141 MIR148B MIR200A MIR200B MIR200C MIR25 MIR30B MIR30C1 MIR30C2 MIR30D MIR429 MIR532 MIR548AA1 MIR548AA2 MIR589 MIR92A2 SDC2 THBS1 THBS2 TNXB (see all 38) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	SDC2	Syndecan 2	Protein Coding	1
2	TNXB	Tenascin XB	Protein Coding	1
3	THBS2	Thrombospondin 2	Protein Coding	1
4	THBS1	Thrombospondin 1	Protein Coding	1
5	MIR589	MicroRNA 589	RNA Gene	1
6	MIR532	MicroRNA 532	RNA Gene	1
7	MIR429	MicroRNA 429	RNA Gene	1
8	COL5A3	Collagen Type V Alpha 3 Chain	Protein Coding	1
9	MIR148B	MicroRNA 148b	RNA Gene	1
10	MIR30D	MicroRNA 30d	RNA Gene	1
11	MIR30C2	MicroRNA 30c-2	RNA Gene	1
12	MIR30C1	MicroRNA 30c-1	RNA Gene	1
13	MIR30B	MicroRNA 30b	RNA Gene	1
14	MIR25	MicroRNA 25	RNA Gene	1
15	MIR200C	MicroRNA 200c	RNA Gene	1
16	MIR200B	MicroRNA 200b	RNA Gene	1
17	MIR200A	MicroRNA 200a	RNA Gene	1
18	MIR141	MicroRNA 141	RNA Gene	1
19	LAMC1	Laminin Subunit Gamma 1	Protein Coding	1
20	LAMB2	Laminin Subunit Beta 2	Protein Coding	1
21	LAMA4	Laminin Subunit Alpha 4	Protein Coding	1
22	ITGB6	Integrin Subunit Beta 6	Protein Coding	1
23	ITGB5	Integrin Subunit Beta 5	Protein Coding	1
24	ITGA1	Integrin Subunit Alpha 1	Protein Coding	1
25	FN1	Fibronectin 1	Protein Coding	1
26	COL6A3	Collagen Type VI Alpha 3 Chain	Protein Coding	1
27	COL6A2	Collagen Type VI Alpha 2 Chain	Protein Coding	1
28	COL6A1	Collagen Type VI Alpha 1 Chain	Protein Coding	1
29	COL5A2	Collagen Type V Alpha 2 Chain	Protein Coding	1
30	COL5A1	Collagen Type V Alpha 1 Chain	Protein Coding	1
31	COL4A2	Collagen Type IV Alpha 2 Chain	Protein Coding	1
32	COL4A1	Collagen Type IV Alpha 1 Chain	Protein Coding	1
33	COL3A1	Collagen Type III Alpha 1 Chain	Protein Coding	1
34	COL1A2	Collagen Type I Alpha 2 Chain	Protein Coding	1
35	MIR92A2	MicroRNA 92a-2	RNA Gene	1
36	MIR548AA2	MicroRNA 548aa-2	RNA Gene	1
37	MIR548AA1	MicroRNA 548aa-1	RNA Gene	1
38	ITGA11	Integrin Subunit Alpha 11	Protein Coding	1

Disorders associated with miRNA targets in ECM and membrane receptors SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Ehlers-danlos syndrome	Enrichment	COL1A2, COL3A1, COL5A1, COL5A2, THBS2, TNXB	10.70
2	Collagen vi-related dystrophies	Enrichment	COL6A1, COL6A2, COL6A3	7.69
3	Intermediate collagen vi-related muscular dystrophy	Enrichment	COL6A1, COL6A2, COL6A3	7.69
4	Bethlem muscular dystrophy	Enrichment	COL6A1, COL6A2, COL6A3	7.09
5	Ullrich congenital muscular dystrophy 1a	Enrichment	COL6A1, COL6A2, COL6A3	6.69
6	Ehlers-danlos syndrome, classic type, 1	Enrichment	COL1A2, COL5A1, COL5A2	6.39
7	Classic ehlers-danlos syndrome	Enrichment	COL1A2, COL5A1, COL5A2	6.39
8	Bethlem myopathy 1a	Enrichment	COL6A1, COL6A2, COL6A3	6.15
9	Ehlers-danlos syndrome, hypermobility type	Enrichment	COL3A1, TNXB	5.12
10	Ehlers-danlos syndrome, classic type, 2	Enrichment	COL5A1, COL5A2	4.64
11	Brain small vessel disease 1 with or without ocular anomalies	Enrichment	COL4A1, COL4A2	4.34
12	Familial porencephaly	Enrichment	COL4A1, COL4A2	4.12
13	Hemorrhage, intracerebral	Enrichment	COL4A1, COL4A2	3.94
14	Keratoconus	Enrichment	COL4A1, COL5A2	3.94
15	Myopathy	Enrichment	COL6A1, COL6A2, COL6A3	3.73
16	Familial thoracic aortic aneurysm and aortic dissection	Enrichment	COL3A1, COL5A1, COL5A2	3.61
17	Ehlers-danlos syndrome, cardiac valvular type	Enrichment	COL1A2	2.55
18	Cardiomyopathy, dilated, 1jj	Enrichment	LAMA4	2.55
19	Acrogeria, gottron type	Enrichment	COL3A1	2.55
20	Ullrich congenital muscular dystrophy 1b	Enrichment	COL6A2	2.55
21	Combined osteogenesis imperfecta and ehlers-danlos syndrome 2	Enrichment	COL1A2	2.55
22	Myosclerosis, autosomal recessive	Enrichment	COL6A2	2.55
23	Porencephaly	Enrichment	COL4A1	2.55
24	Ullrich congenital muscular dystrophy 1c	Enrichment	COL6A3	2.55
25	Dystonia 27	Enrichment	COL6A3	2.55
26	Qualitative or quantitative defects of collagen 6	Enrichment	COL6A2	2.55
27	Bethlem myopathy 1b	Enrichment	COL6A2	2.55
28	Amelogenesis imperfecta, type ih	Enrichment	ITGB6	2.55
29	Col4a1-related disorders	Enrichment	COL4A1	2.55
30	Bethlem myopathy 1c	Enrichment	COL6A3	2.55
31	Col4a1 or col4a2-related cerebral small vessel disease	Enrichment	COL4A1	2.55
32	Pneumothorax	Enrichment	COL5A1	2.55
33	Abdominal aortic aneurysm	Enrichment	COL3A1	2.55
34	Cerebral palsy	Enrichment	COL4A1, COL4A2	2.28
35	Ehlers-danlos syndrome, vascular type	Enrichment	COL3A1	2.25
36	Spondyloepimetaphyseal dysplasia, strudwick type	Enrichment	FN1	2.25
37	Spondylometaphyseal dysplasia, corner fracture type	Enrichment	FN1	2.25
38	Bruck syndrome 1	Enrichment	COL1A2	2.25
39	Myasthenic syndrome, congenital, 5	Enrichment	LAMB2	2.25
40	Pierson syndrome	Enrichment	LAMB2	2.25
41	Encephalopathy, progressive, early-onset, with brain edema and/or leukoencephalopathy, 1	Enrichment	COL4A2	2.25
42	Fibromuscular dysplasia, multifocal	Enrichment	COL5A1	2.25
43	Ehlers-danlos syndrome, arthrochalasia type, 2	Enrichment	COL1A2	2.25
44	Polymicrogyria with or without vascular-type ehlers-danlos syndrome	Enrichment	COL3A1	2.25
45	Nephrotic syndrome, type 5, with or without ocular abnormalities	Enrichment	LAMB2	2.25
46	Aortic dissection	Enrichment	COL3A1	2.25
47	Ehlers-danlos/osteogenesis imperfecta syndrome	Enrichment	COL1A2	2.25
48	Dentinogenesis imperfecta	Enrichment	COL1A2	2.25
49	Nephrotic syndrome	Enrichment	FN1, LAMB2	2.19
50	Retinal arteries, tortuosity of	Enrichment	COL4A1	2.08
51	Telecanthus	Enrichment	COL5A2	2.08
52	Glomerulopathy with fibronectin deposits 2	Enrichment	FN1	2.08
53	Ehlers-danlos syndrome, classic-like, 1	Enrichment	TNXB	2.08
54	Brain small vessel disease 2	Enrichment	COL4A2	2.08
55	Microangiopathy and leukoencephalopathy, pontine, autosomal dominant	Enrichment	COL4A1	2.08
56	Vesicoureteral reflux 8	Enrichment	TNXB	2.08
57	Ehlers-danlos syndrome, classic-like, 3	Enrichment	THBS2	2.08
58	Angiopathy, hereditary, with nephropathy, aneurysms, and muscle cramps	Enrichment	COL4A1	2.08
59	Familial vesicoureteral reflux	Enrichment	TNXB	2.08
60	High bone mass osteogenesis imperfecta	Enrichment	COL1A2	2.08
61	Alopecia - intellectual disability syndrome	Enrichment	ITGB6	2.08
62	Ehlers-danlos syndrome, arthrochalasia type, 1	Enrichment	COL1A2	1.95
63	Amelogenesis imperfecta, type iiia	Enrichment	ITGB6	1.95
64	Schizencephaly	Enrichment	COL4A1	1.95
65	Osteogenesis imperfecta with normal sclerae, dominant form	Enrichment	COL1A2	1.95
66	Familial cerebral saccular aneurysm	Enrichment	COL3A1	1.86
67	Osteogenesis imperfecta, type i	Enrichment	COL1A2	1.78
68	Adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency	Enrichment	TNXB	1.78
69	Anterior segment dysgenesis 5	Enrichment	COL4A1	1.78
70	Inguinal hernia	Enrichment	COL5A1	1.78
71	Pain disorder	Enrichment	COL5A1	1.78
72	21-hydroxylase-deficient congenital adrenal hyperplasia	Enrichment	TNXB	1.78
73	Osteogenesis imperfecta, type ii	Enrichment	COL1A2	1.71
74	Intervertebral disc disease	Enrichment	THBS2	1.71
75	Gastroesophageal reflux	Enrichment	COL5A1	1.65
76	Spastic paraplegia 4, autosomal dominant	Enrichment	COL3A1	1.65
77	Orthostatic intolerance	Enrichment	COL5A1	1.65
78	Familial thoracic aortic aneurysm and dissection	Enrichment	COL3A1	1.60
79	Peters-plus syndrome	Enrichment	COL4A1	1.56
80	Amelogenesis imperfecta, type ie	Enrichment	ITGB6	1.56
81	Primary bone dysplasia	Enrichment	COL1A2	1.56
82	Osteochondrodysplasia	Enrichment	COL1A2	1.52
83	Cutis laxa	Enrichment	COL5A1	1.48
84	Osteogenesis imperfecta, type iv	Enrichment	COL1A2	1.45
85	Clubfoot, congenital, with or without deficiency of long bones and/or mirror-image polydactyly	Enrichment	COL5A1	1.45
86	Clubfoot	Enrichment	COL5A1	1.45
87	Osteoporosis	Enrichment	COL1A2	1.41
88	Lipoid congenital adrenal hyperplasia	Enrichment	TNXB	1.41
89	Aortic aneurysm, familial thoracic 1	Enrichment	COL3A1	1.41
90	Walker-warburg syndrome	Enrichment	COL4A1	1.41
91	Cataract	Enrichment	COL5A1	1.41
92	Corpus callosum, agenesis of	Enrichment	COL4A1	1.38
93	Osteogenesis imperfecta, type iii	Enrichment	COL1A2	1.38
94	Anterior segment dysgenesis	Enrichment	COL4A1	1.38
95	Kidney disease	Enrichment	LAMB2	1.38
96	Isolated corpus callosum agenesis	Enrichment	COL4A1	1.38
97	Intellectual disability-hypoplastic corpus callosum-preauricular tag syndrome	Enrichment	COL4A1	1.38
98	Beckwith-wiedemann syndrome	Enrichment	COL6A1	1.31
99	Brittle bone disorder	Enrichment	COL1A2	1.20
100	Muscular dystrophy	Enrichment	COL6A2	1.19
101	Connective tissue disease	Enrichment	COL5A1	1.07
102	Cakut	Enrichment	COL4A1	1.04
103	Familial isolated dilated cardiomyopathy	Enrichment	LAMA4	0.86
104	Primary ovarian insufficiency	Enrichment	THBS1	0.82
105	Microcephaly	Enrichment	COL4A1	0.53

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

miRNA targets in ECM and membrane receptors

Pathway Network for miRNA targets in ECM and membrane receptors

Member Pathways for miRNA targets in ECM and membrane receptors

Pathways in the miRNA targets in ECM and membrane receptors SuperPath

Associated Genes for miRNA targets in ECM and membrane receptors

Associated Disorders for miRNA targets in ECM and membrane receptors

Disorders associated with miRNA targets in ECM and membrane receptors SuperPath

STRING Interaction Network for miRNA targets in ECM and membrane receptors

Sources for miRNA targets in ECM and membrane receptors