miRNAs involved in DNA damage response

No Pathway Network information available for miRNAs involved in DNA damage response

Pathways in the miRNAs involved in DNA damage response SuperPath

#	Name	Source	Genes
1	miRNAs involved in DNA damage response	WikiPathways	ABL1 ATM CCND1 CCND3 CCNE1 CDC25A CDK6 CDKN1A CDKN1B CREB1 E2F1 H2AX MIR100 MIR106B MIR143 MIR145 MIR15A MIR15B MIR16-1 MIR17 MIR181A1 MIR181B1 MIR18A MIR195 MIR19A MIR19B1 MIR203A MIR20A MIR21 MIR210 MIR221 MIR222 MIR223 MIR23A MIR23B MIR25 MIR27A MIR27B MIR29A MIR29B1 MIR29C MIR3074 MIR330 MIR34B MIR34C MIR371A MIR372 MIR373 MIR374B MIR421 MIR424 MIR449A MIR449B MIR450A2 MIR450B MIR497 MIR503 MIR542 MIR92A1 MIR93 MIRLET7A1 MIRLET7B MIRLET7D MIRLET7F1 MYC RAD52 TP53 (see all 67) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MIR449B	MicroRNA 449b	RNA Gene	1
2	CCNE1	Cyclin E1	Protein Coding	1
3	CCND3	Cyclin D3	Protein Coding	1
4	TP53	Tumor Protein P53	Protein Coding	1
5	MIR421	MicroRNA 421	RNA Gene	1
6	MIR542	MicroRNA 542	RNA Gene	1
7	CCND1	Cyclin D1	Protein Coding	1
8	RAD52	RAD52 DNA Repair Protein	Protein Coding	1
9	MIR503	MicroRNA 503	RNA Gene	1
10	MIR497	MicroRNA 497	RNA Gene	1
11	MIR424	MicroRNA 424	RNA Gene	1
12	ATM	ATM Serine/Threonine Kinase	Protein Coding	1
13	MYC	MYC Proto-Oncogene, BHLH Transcription Factor	Protein Coding	1
14	MIR330	MicroRNA 330	RNA Gene	1
15	MIR93	MicroRNA 93	RNA Gene	1
16	MIR92A1	MicroRNA 92a-1	RNA Gene	1
17	MIR34C	MicroRNA 34c	RNA Gene	1
18	MIR34B	MicroRNA 34b	RNA Gene	1
19	MIR29C	MicroRNA 29c	RNA Gene	1
20	MIR29A	MicroRNA 29a	RNA Gene	1
21	MIR27B	MicroRNA 27b	RNA Gene	1
22	MIR27A	MicroRNA 27a	RNA Gene	1
23	MIR25	MicroRNA 25	RNA Gene	1
24	MIR23B	MicroRNA 23b	RNA Gene	1
25	MIR23A	MicroRNA 23a	RNA Gene	1
26	MIR223	MicroRNA 223	RNA Gene	1
27	MIR222	MicroRNA 222	RNA Gene	1
28	MIR221	MicroRNA 221	RNA Gene	1
29	MIR181A1	MicroRNA 181a-1	RNA Gene	1
30	MIR210	MicroRNA 210	RNA Gene	1
31	MIR21	MicroRNA 21	RNA Gene	1
32	MIR203A	MicroRNA 203a	RNA Gene	1
33	MIR20A	MicroRNA 20a	RNA Gene	1
34	MIR19A	MicroRNA 19a	RNA Gene	1
35	MIR195	MicroRNA 195	RNA Gene	1
36	MIR18A	MicroRNA 18a	RNA Gene	1
37	MIR17	MicroRNA 17	RNA Gene	1
38	MIR16-1	MicroRNA 16-1	RNA Gene	1
39	MIR15B	MicroRNA 15b	RNA Gene	1
40	MIR15A	MicroRNA 15a	RNA Gene	1
41	MIR145	MicroRNA 145	RNA Gene	1
42	MIR143	MicroRNA 143	RNA Gene	1
43	MIR106B	MicroRNA 106b	RNA Gene	1
44	MIR100	MicroRNA 100	RNA Gene	1
45	MIRLET7D	MicroRNA Let-7d	RNA Gene	1
46	MIRLET7B	MicroRNA Let-7b	RNA Gene	1
47	H2AX	H2A.X Variant Histone	Protein Coding	1
48	ABL1	ABL Proto-Oncogene 1, Non-Receptor Tyrosine Kinase	Protein Coding	1
49	E2F1	E2F Transcription Factor 1	Protein Coding	1
50	CREB1	CAMP Responsive Element Binding Protein 1	Protein Coding	1
51	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
52	CDKN1A	Cyclin Dependent Kinase Inhibitor 1A	Protein Coding	1
53	CDK6	Cyclin Dependent Kinase 6	Protein Coding	1
54	MIR374B	MicroRNA 374b	RNA Gene	1
55	MIR450A2	MicroRNA 450a-2	RNA Gene	1
56	MIR449A	MicroRNA 449a	RNA Gene	1
57	MIR373	MicroRNA 373	RNA Gene	1
58	MIR372	MicroRNA 372	RNA Gene	1
59	MIR371A	MicroRNA 371a	RNA Gene	1
60	MIR29B1	MicroRNA 29b-1	RNA Gene	1
61	MIR19B1	MicroRNA 19b-1	RNA Gene	1
62	MIR181B1	MicroRNA 181b-1	RNA Gene	1
63	MIRLET7F1	MicroRNA Let-7f-1	RNA Gene	1
64	MIRLET7A1	MicroRNA Let-7a-1	RNA Gene	1
65	CDC25A	Cell Division Cycle 25A	Protein Coding	1
66	MIR3074	MicroRNA 3074	RNA Gene	1
67	MIR450B	MicroRNA 450b	RNA Gene	1

Disorders associated with miRNAs involved in DNA damage response SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Leukemia, chronic lymphocytic	Enrichment	ATM, CCND1, TP53	4.87
2	Adenocarcinoma	Enrichment	ATM, TP53	4.14
3	Mantle cell lymphoma	Enrichment	ATM, CCND1	3.84
4	Bladder cancer	Enrichment	ATM, CDKN1A, TP53	3.42
5	Multiple endocrine neoplasia, type i	Enrichment	CDKN1A, CDKN1B	3.30
6	B-lymphoblastic leukemia/lymphoma with t(9;22)(q34.1;q11.2)	Enrichment	ABL1, TP53	3.30
7	Lip and oral cavity carcinoma	Enrichment	ABL1, TP53	2.81
8	Myeloma, multiple	Enrichment	ATM, CCND1, TP53	2.58
9	Gliosarcoma	Enrichment	ATM, TP53	2.56
10	Giant cell glioblastoma	Enrichment	ATM, TP53	2.51
11	Microcephaly 12, primary, autosomal recessive	Enrichment	CDK6	2.31
12	Bone marrow failure syndrome 5	Enrichment	TP53	2.31
13	Papilloma of choroid plexus	Enrichment	TP53	2.31
14	Basal cell carcinoma 7	Enrichment	TP53	2.31
15	Anaplastic thyroid carcinoma	Enrichment	TP53	2.31
16	Neuroendocrine tumor	Enrichment	CDKN1B	2.31
17	Endometrial serous adenocarcinoma	Enrichment	ATM	2.31
18	Ductal carcinoma in situ	Enrichment	TP53	2.31
19	Thyroid gland undifferentiated carcinoma	Enrichment	TP53	2.31
20	Small-cell carcinoma of the ovary of hypercalcemic type	Enrichment	TP53	2.31
21	Diffuse pediatric-type high-grade glioma, h3-wildtype and idh-wildtype	Enrichment	TP53	2.31
22	B-cell non-hodgkin lymphoma	Enrichment	ATM	2.31
23	Choroid plexus cancer	Enrichment	TP53	2.31
24	Pleomorphic xanthoastrocytoma	Enrichment	TP53	2.31
25	Precursor t-cell acute lymphoblastic leukemia	Enrichment	ABL1, MYC	2.25
26	Pancreatic cancer	Enrichment	ATM, TP53	2.17
27	Prostate cancer	Enrichment	ATM, TP53	2.05
28	Colorectal cancer	Enrichment	ATM, CCND1, TP53	2.04
29	Burkitt lymphoma	Enrichment	MYC	2.01
30	Adrenocortical carcinoma, hereditary	Enrichment	TP53	2.01
31	Cervical cancer	Enrichment	TP53	2.01
32	Histiocytoma, angiomatoid fibrous	Enrichment	CREB1	2.01
33	Lymphoma, hodgkin, classic	Enrichment	TP53	2.01
34	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	2.01
35	Congenital heart defects and skeletal malformations syndrome	Enrichment	ABL1	2.01
36	Cardiac valvular dysplasia, x-linked	Enrichment	ATM	2.01
37	Congenital fibrosarcoma	Enrichment	TP53	2.01
38	High grade glioma	Enrichment	ATM	2.01
39	Li-fraumeni syndrome 1	Enrichment	TP53	2.01
40	Sarcoma	Enrichment	TP53	2.01
41	Cervix carcinoma	Enrichment	TP53	2.01
42	Hodgkin's lymphoma	Enrichment	TP53	2.01
43	T-cell prolymphocytic leukemia	Enrichment	ATM	2.01
44	Pleomorphic rhabdomyosarcoma	Enrichment	TP53	2.01
45	Ovarian cancer	Enrichment	ATM, CDKN1B, TP53	1.87
46	Ataxia-telangiectasia	Enrichment	ATM	1.83
47	Polycythemia vera	Enrichment	ATM	1.83
48	Osteogenic sarcoma	Enrichment	TP53	1.83
49	Nasopharyngeal carcinoma	Enrichment	TP53	1.83
50	Koolen-de vries syndrome	Enrichment	ATM	1.83
51	High-grade b-cell lymphoma double-hit/triple-hit	Enrichment	MYC	1.83
52	Atypical teratoid rhabdoid tumor	Enrichment	TP53	1.83
53	Anaplastic astrocytoma	Enrichment	TP53	1.83
54	Squamous cell carcinoma	Enrichment	TP53	1.83
55	T-cell acute lymphoblastic leukemia	Enrichment	ABL1	1.83
56	Bone osteosarcoma	Enrichment	TP53	1.83
57	Melanoma of soft tissue	Enrichment	CREB1	1.83
58	Gastric cancer	Enrichment	ATM, TP53	1.72
59	Small cell cancer of the lung	Enrichment	TP53	1.71
60	Thyroid cancer, nonmedullary, 1	Enrichment	TP53	1.71
61	Lung sarcomatoid carcinoma	Enrichment	TP53	1.71
62	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	ABL1	1.71
63	Embryonal rhabdomyosarcoma	Enrichment	TP53	1.71
64	Primary hyperparathyroidism	Enrichment	CDKN1B	1.71
65	Oculomotor apraxia	Enrichment	ATM	1.71
66	Hereditary breast carcinoma	Enrichment	ATM, TP53	1.70
67	Von hippel-lindau syndrome	Enrichment	CCND1	1.61
68	Rhabdomyosarcoma 2	Enrichment	TP53	1.61
69	Lymphoma	Enrichment	TP53	1.61
70	Glioblastoma	Enrichment	ATM	1.61
71	Acute megakaryocytic leukemia	Enrichment	TP53	1.61
72	Inherited cancer-predisposing syndrome	Enrichment	ATM, CDKN1B, TP53	1.56
73	Li-fraumeni syndrome	Enrichment	TP53	1.53
74	Adrenocortical carcinoma	Enrichment	TP53	1.53
75	Clear cell renal cell carcinoma	Enrichment	ATM	1.53
76	Breast adenocarcinoma	Enrichment	TP53	1.53
77	Hereditary breast ovarian cancer syndrome	Enrichment	ATM, TP53	1.52
78	Esophageal cancer	Enrichment	TP53	1.47
79	Squamous cell carcinoma, head and neck	Enrichment	TP53	1.47
80	Leukemia, chronic myeloid	Enrichment	ABL1	1.47
81	Renal cell carcinoma, papillary, 1	Enrichment	ATM	1.47
82	Essential thrombocythemia	Enrichment	TP53	1.47
83	Gallbladder cancer	Enrichment	TP53	1.47
84	Moyamoya angiopathy	Enrichment	ABL1	1.47
85	Glioma susceptibility 1	Enrichment	TP53	1.41
86	Lymphoma, non-hodgkin, familial	Enrichment	TP53	1.41
87	Adult hepatocellular carcinoma	Enrichment	TP53	1.36
88	Primary hyperaldosteronism	Enrichment	TP53	1.36
89	Colonic benign neoplasm	Enrichment	ATM	1.36
90	Lynch syndrome 1	Enrichment	ATM	1.32
91	Familial colorectal cancer	Enrichment	TP53	1.32
92	Breast cancer	Enrichment	ATM, TP53	1.28
93	Immune deficiency disease	Enrichment	ATM	1.28
94	Myelodysplastic syndrome	Enrichment	TP53	1.28
95	Uterine corpus cancer	Enrichment	ATM	1.28
96	Familial colorectal cancer type x	Enrichment	ATM	1.28
97	Breast-ovarian cancer, familial 1	Enrichment	ATM	1.21
98	Lung cancer susceptibility 3	Enrichment	TP53	1.17
99	Heart disease	Enrichment	ABL1	1.17
100	Renal cell carcinoma, nonpapillary	Enrichment	ATM	1.14
101	Rhabdomyosarcoma	Enrichment	TP53	1.12
102	Polycystic liver disease	Enrichment	CDC25A	1.09
103	Autosomal dominant polycystic liver disease	Enrichment	CDC25A	1.09
104	Diffuse large b-cell lymphoma	Enrichment	TP53	1.05
105	Endometrial cancer	Enrichment	ATM	1.01
106	Hepatoblastoma	Enrichment	TP53	1.01
107	Hepatocellular carcinoma	Enrichment	TP53	0.99
108	Diamond-blackfan anemia 1	Enrichment	TP53	0.97
109	Primary autosomal recessive microcephaly	Enrichment	CDK6	0.83
110	Diamond-blackfan anemia	Enrichment	TP53	0.79
111	Leukemia, acute myeloid	Enrichment	TP53	0.74
112	Microcephaly	Enrichment	ABL1	0.34

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

miRNAs involved in DNA damage response

Pathway Network for miRNAs involved in DNA damage response

Member Pathways for miRNAs involved in DNA damage response

Pathways in the miRNAs involved in DNA damage response SuperPath

Associated Genes for miRNAs involved in DNA damage response

Associated Disorders for miRNAs involved in DNA damage response

Disorders associated with miRNAs involved in DNA damage response SuperPath

STRING Interaction Network for miRNAs involved in DNA damage response

Sources for miRNAs involved in DNA damage response