Mitochondrial immune response to SARS-CoV-2

No Pathway Network information available for Mitochondrial immune response to SARS-CoV-2

Pathways in the Mitochondrial immune response to SARS-CoV-2 SuperPath

#	Name	Source	Genes
1	Mitochondrial immune response to SARS-CoV-2	WikiPathways	ACAD9 ACE AGTR1 AGTR2 BCS1L CTSL ECSIT IFN1@ IKBKE IRF3 IRF7 LOC124905021 MAVS NDUFAF1 NDUFB9 NFKB1 NFKB2 NLRX1 RIGI TBK1 TICAM1 TRAF3 TRAF6 (see all 23) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	ACE	Angiotensin I Converting Enzyme	Protein Coding	1
2	TRAF6	TNF Receptor Associated Factor 6	Protein Coding	1
3	TRAF3	TNF Receptor Associated Factor 3	Protein Coding	1
4	BCS1L	BCS1 Ubiquinol-Cytochrome C Reductase Complex Chaperone	Protein Coding	1
5	NFKB2	Nuclear Factor Kappa B Subunit 2	Protein Coding	1
6	NFKB1	Nuclear Factor Kappa B Subunit 1	Protein Coding	1
7	NDUFB9	NADH:Ubiquinone Oxidoreductase Subunit B9	Protein Coding	1
8	IRF7	Interferon Regulatory Factor 7	Protein Coding	1
9	IRF3	Interferon Regulatory Factor 3	Protein Coding	1
10	TBK1	TANK Binding Kinase 1	Protein Coding	1
11	ACAD9	Acyl-CoA Dehydrogenase Family Member 9	Protein Coding	1
12	RIGI	RNA Sensor RIG-I	Protein Coding	1
13	AGTR2	Angiotensin II Receptor Type 2	Protein Coding	1
14	AGTR1	Angiotensin II Receptor Type 1	Protein Coding	1
15	CTSL	Cathepsin L	Protein Coding	1
16	TICAM1	TIR Domain Containing Adaptor Molecule 1	Protein Coding	1
17	LOC124905021	Uncharacterized LOC124905021	RNA Gene	1
18	NLRX1	NLR Family Member X1	Protein Coding	1
19	MAVS	Mitochondrial Antiviral Signaling Protein	Protein Coding	1
20	ECSIT	ECSIT Signaling Integrator	Protein Coding	1
21	NDUFAF1	NADH:Ubiquinone Oxidoreductase Complex Assembly Factor 1	Protein Coding	1
22	IFN1@	Interferon, Type 1, Cluster	Gene Cluster	1
23	IKBKE	Inhibitor Of Nuclear Factor Kappa B Kinase Subunit Epsilon	Protein Coding	1

Disorders associated with Mitochondrial immune response to SARS-CoV-2 SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Herpes simplex virus encephalitis	Enrichment	TBK1, TICAM1, TRAF3	7.37
2	Mitochondrial complex i deficiency, nuclear type 1	Enrichment	ACAD9, NDUFAF1, NDUFB9	4.46
3	Renal tubular dysgenesis	Enrichment	ACE, AGTR1	4.39
4	Common variable immunodeficiency	Enrichment	NFKB1, NFKB2	4.24
5	Multisystem inflammatory syndrome in children	Enrichment	IRF3, TRAF3	3.21
6	Immunodeficiency 39 viral infections	Enrichment	IRF7	2.77
7	Encephalopathy, acute, infection-induced 7	Enrichment	IRF3	2.77
8	Microvascular complications of diabetes 3	Enrichment	ACE	2.77
9	Encephalopathy, acute, infection-induced 6	Enrichment	TICAM1	2.77
10	Bjornstad syndrome	Enrichment	BCS1L	2.77
11	Mitochondrial complex i deficiency, nuclear type 11	Enrichment	NDUFAF1	2.77
12	Immunodeficiency 132a	Enrichment	TRAF3	2.77
13	Immunodeficiency 132b	Enrichment	TRAF3	2.77
14	Immunodeficiency 39	Enrichment	IRF7	2.77
15	Gracile syndrome	Enrichment	BCS1L	2.77
16	Autoinflammation with arthritis and vasculitis	Enrichment	TBK1	2.77
17	Mitochondrial complex i deficiency, nuclear type 24	Enrichment	NDUFB9	2.77
18	Singleton-merten syndrome 2	Enrichment	RIGI	2.77
19	Corticobasal syndrome	Enrichment	TBK1	2.77
20	Deficiency in anterior pituitary function - variable immunodeficiency syndrome	Enrichment	NFKB2	2.77
21	Encephalopathy, acute, infection-induced 8	Enrichment	TBK1	2.77
22	Renal tubulopathy-encephalopathy-liver failure syndrome	Enrichment	BCS1L	2.77
23	Immunodeficiency, common variable, 12, with autoimmunity	Enrichment	NFKB1	2.47
24	Immunodeficiency, common variable, 10	Enrichment	NFKB2	2.47
25	Frontotemporal dementia and/or amyotrophic lateral sclerosis 4	Enrichment	TBK1	2.47
26	Singleton-merten syndrome	Enrichment	RIGI	2.47
27	Common variable immunodeficiency 12	Enrichment	NFKB1	2.47
28	Mitochondrial complex iii deficiency, nuclear type 1	Enrichment	BCS1L	2.29
29	Mitochondrial complex i deficiency, nuclear type 20	Enrichment	ACAD9	2.29
30	Immunodeficiency, common variable, 1	Enrichment	NFKB2	2.17
31	Ectodermal dysplasia 10a, hypohidrotic/hair/nail type, autosomal dominant	Enrichment	TRAF6	2.07
32	Hemorrhage, intracerebral	Enrichment	ACE	1.99
33	Motor neuron disease	Enrichment	TBK1	1.93
34	Progressive non-fluent aphasia	Enrichment	TBK1	1.82
35	Frontotemporal dementia and/or amyotrophic lateral sclerosis 1	Enrichment	TBK1	1.77
36	Stroke, ischemic	Enrichment	ACE	1.77
37	Ciliary dyskinesia, primary, 3	Enrichment	NFKB1	1.77
38	Movement disease	Enrichment	BCS1L	1.73
39	Isolated complex iii deficiency	Enrichment	BCS1L	1.73
40	Hypertension, essential	Enrichment	AGTR1	1.55
41	Myocardial infarction	Enrichment	ACE	1.44
42	Cakut	Enrichment	ACE	1.25
43	Non-syndromic x-linked intellectual disability	Enrichment	AGTR2	1.23
44	Frontotemporal dementia and/or amyotrophic lateral sclerosis 7	Enrichment	TBK1	1.03
45	Leigh syndrome, nuclear	Enrichment	BCS1L	0.96
46	Leigh disease	Enrichment	BCS1L	0.92
47	Microcephaly	Enrichment	BCS1L	0.72

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Mitochondrial immune response to SARS-CoV-2

Pathway Network for Mitochondrial immune response to SARS-CoV-2

Member Pathways for Mitochondrial immune response to SARS-CoV-2

Pathways in the Mitochondrial immune response to SARS-CoV-2 SuperPath

Associated Genes for Mitochondrial immune response to SARS-CoV-2

Associated Disorders for Mitochondrial immune response to SARS-CoV-2

Disorders associated with Mitochondrial immune response to SARS-CoV-2 SuperPath

STRING Interaction Network for Mitochondrial immune response to SARS-CoV-2

Sources for Mitochondrial immune response to SARS-CoV-2