Mitochondrial translation

Pathway network for the Mitochondrial translation SuperPath

Sources:

Reactome

Pathways in the Mitochondrial translation SuperPath

#	Name	Source	Genes
1	Mitochondrial translation	Reactome	AURKAIP1 CHCHD1 DAP3 ERAL1 GADD45GIP1 GFM1 GFM2 KGD4 MALSU1 MIEF1 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL30 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL46 MRPL47 MRPL48 MRPL49 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS30 MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 MRRF MT-ATP6 MT-ATP8 MT-CO1 MT-CO2 MT-CO3 MT-CYB MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND4L MT-ND5 MT-ND6 MTFMT MTIF2 MTIF3 MTRES1 MTRF1 MTRF1L MTRFR NDUFAB1 OXA1L PTCD3 TSFM TUFM (see all 112) (see less)
2	Mitochondrial translation termination	Reactome	AURKAIP1 CHCHD1 DAP3 ERAL1 GADD45GIP1 GFM2 KGD4 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL30 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL46 MRPL47 MRPL48 MRPL49 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS30 MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 MRRF MT-ATP6 MT-ATP8 MT-CO1 MT-CO2 MT-CO3 MT-CYB MT-ND1 MT-ND2 MT-ND3 MT-ND4 MT-ND4L MT-ND5 MT-ND6 MTRF1 MTRF1L OXA1L PTCD3 (see all 101) (see less)
3	Mitochondrial ribosome-associated quality control	Reactome	AURKAIP1 CHCHD1 DAP3 ERAL1 GADD45GIP1 KGD4 MALSU1 MIEF1 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL30 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL46 MRPL47 MRPL48 MRPL49 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS30 MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 MTRES1 MTRFR NDUFAB1 OXA1L PTCD3 (see all 89) (see less)
4	Mitochondrial translation initiation	Reactome	AURKAIP1 CHCHD1 DAP3 ERAL1 GADD45GIP1 KGD4 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL30 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL46 MRPL47 MRPL48 MRPL49 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS30 MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 MTFMT MTIF2 MTIF3 OXA1L PTCD3 (see all 87) (see less)
5	Mitochondrial translation elongation	Reactome	AURKAIP1 CHCHD1 DAP3 ERAL1 GADD45GIP1 GFM1 KGD4 MRPL1 MRPL10 MRPL11 MRPL12 MRPL13 MRPL14 MRPL15 MRPL16 MRPL17 MRPL18 MRPL19 MRPL2 MRPL20 MRPL21 MRPL22 MRPL23 MRPL24 MRPL27 MRPL28 MRPL3 MRPL30 MRPL32 MRPL33 MRPL34 MRPL35 MRPL36 MRPL37 MRPL38 MRPL39 MRPL4 MRPL40 MRPL41 MRPL42 MRPL43 MRPL44 MRPL46 MRPL47 MRPL48 MRPL49 MRPL50 MRPL51 MRPL52 MRPL53 MRPL54 MRPL55 MRPL57 MRPL58 MRPL9 MRPS10 MRPS11 MRPS12 MRPS14 MRPS15 MRPS16 MRPS17 MRPS18A MRPS18B MRPS18C MRPS2 MRPS21 MRPS22 MRPS23 MRPS24 MRPS25 MRPS26 MRPS27 MRPS28 MRPS30 MRPS31 MRPS33 MRPS34 MRPS35 MRPS5 MRPS6 MRPS7 MRPS9 OXA1L PTCD3 TSFM TUFM (see all 87) (see less)

Gene overlap in member pathways for Mitochondrial translation SuperPath

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	MRPS31	Mitochondrial Ribosomal Protein S31	Protein Coding	5
2	MRPL28	Mitochondrial Ribosomal Protein L28	Protein Coding	5
3	MRPS30	Mitochondrial Ribosomal Protein S30	Protein Coding	5
4	MRPL3	Mitochondrial Ribosomal Protein L3~Name Same As:- HGNC:14043	Protein Coding	5
5	MRPL53	Mitochondrial Ribosomal Protein L53	Protein Coding	5
6	MRPL54	Mitochondrial Ribosomal Protein L54	Protein Coding	5
7	CHCHD1	Coiled-Coil-Helix-Coiled-Coil-Helix Domain Containing 1	Protein Coding	5
8	MRPL52	Mitochondrial Ribosomal Protein L52	Protein Coding	5
9	MRPL10	Mitochondrial Ribosomal Protein L10	Protein Coding	5
10	MRPL55	Mitochondrial Ribosomal Protein L55	Protein Coding	5
11	MRPL21	Mitochondrial Ribosomal Protein L21	Protein Coding	5
12	MRPS27	Mitochondrial Ribosomal Protein S27	Protein Coding	5
13	ERAL1	Era Like 12S Mitochondrial RRNA Chaperone 1	Protein Coding	5
14	MRPL46	Mitochondrial Ribosomal Protein L46	Protein Coding	5
15	MRPS28	Mitochondrial Ribosomal Protein S28	Protein Coding	5
16	MRPS18B	Mitochondrial Ribosomal Protein S18B	Protein Coding	5
17	MRPL42	Mitochondrial Ribosomal Protein L42	Protein Coding	5
18	MRPL13	Mitochondrial Ribosomal Protein L13	Protein Coding	5
19	MRPL18	Mitochondrial Ribosomal Protein L18	Protein Coding	5
20	MRPL15	Mitochondrial Ribosomal Protein L15	Protein Coding	5
21	MRPL22	Mitochondrial Ribosomal Protein L22	Protein Coding	5
22	MRPL58	Mitochondrial Ribosomal Protein L58	Protein Coding	5
23	OXA1L	OXA1L Mitochondrial Inner Membrane Insertase	Protein Coding	5
24	MRPS16	Mitochondrial Ribosomal Protein S16	Protein Coding	5
25	MRPS18C	Mitochondrial Ribosomal Protein S18C	Protein Coding	5
26	MRPL2	Mitochondrial Ribosomal Protein L2	Protein Coding	5
27	MRPL4	Mitochondrial Ribosomal Protein L4	Protein Coding	5
28	MRPS7	Mitochondrial Ribosomal Protein S7	Protein Coding	5
29	MRPS2	Mitochondrial Ribosomal Protein S2	Protein Coding	5
30	MRPL37	Mitochondrial Ribosomal Protein L37	Protein Coding	5
31	MRPL51	Mitochondrial Ribosomal Protein L51	Protein Coding	5
32	MRPL30	Mitochondrial Ribosomal Protein L30	Protein Coding	5
33	MRPL27	Mitochondrial Ribosomal Protein L27	Protein Coding	5
34	MRPL35	Mitochondrial Ribosomal Protein L35	Protein Coding	5
35	MRPS17	Mitochondrial Ribosomal Protein S17	Protein Coding	5
36	MRPL48	Mitochondrial Ribosomal Protein L48	Protein Coding	5
37	MRPS23	Mitochondrial Ribosomal Protein S23	Protein Coding	5
38	MRPS33	Mitochondrial Ribosomal Protein S33	Protein Coding	5
39	MRPL39	Mitochondrial Ribosomal Protein L39	Protein Coding	5
40	MRPS21	Mitochondrial Ribosomal Protein S21	Protein Coding	5
41	MRPL50	Mitochondrial Ribosomal Protein L50	Protein Coding	5
42	MRPL16	Mitochondrial Ribosomal Protein L16	Protein Coding	5
43	AURKAIP1	Aurora Kinase A Interacting Protein 1	Protein Coding	5
44	PTCD3	Pentatricopeptide Repeat Domain 3	Protein Coding	5
45	MRPL20	Mitochondrial Ribosomal Protein L20	Protein Coding	5
46	MRPS18A	Mitochondrial Ribosomal Protein S18A	Protein Coding	5
47	MRPS10	Mitochondrial Ribosomal Protein S10	Protein Coding	5
48	MRPS22	Mitochondrial Ribosomal Protein S22	Protein Coding	5
49	MRPL47	Mitochondrial Ribosomal Protein L47	Protein Coding	5
50	MRPS35	Mitochondrial Ribosomal Protein S35	Protein Coding	5
51	MRPL23	Mitochondrial Ribosomal Protein L23~Name Same As:- HGNC:14038	Protein Coding	5
52	MRPL12	Mitochondrial Ribosomal Protein L12	Protein Coding	5
53	MRPS12	Mitochondrial Ribosomal Protein S12	Protein Coding	5
54	MRPL17	Mitochondrial Ribosomal Protein L17	Protein Coding	5
55	MRPS14	Mitochondrial Ribosomal Protein S14	Protein Coding	5
56	MRPS25	Mitochondrial Ribosomal Protein S25	Protein Coding	5
57	MRPL14	Mitochondrial Ribosomal Protein L14	Protein Coding	5
58	MRPS26	Mitochondrial Ribosomal Protein S26	Protein Coding	5
59	MRPS24	Mitochondrial Ribosomal Protein S24	Protein Coding	5
60	MRPS15	Mitochondrial Ribosomal Protein S15	Protein Coding	5
61	MRPS11	Mitochondrial Ribosomal Protein S11	Protein Coding	5
62	MRPS9	Mitochondrial Ribosomal Protein S9	Protein Coding	5
63	MRPS6	Mitochondrial Ribosomal Protein S6	Protein Coding	5
64	MRPS5	Mitochondrial Ribosomal Protein S5	Protein Coding	5
65	MRPL41	Mitochondrial Ribosomal Protein L41	Protein Coding	5
66	MRPL40	Mitochondrial Ribosomal Protein L40	Protein Coding	5
67	MRPL38	Mitochondrial Ribosomal Protein L38	Protein Coding	5
68	MRPL36	Mitochondrial Ribosomal Protein L36	Protein Coding	5
69	MRPL34	Mitochondrial Ribosomal Protein L34	Protein Coding	5
70	MRPL32	Mitochondrial Ribosomal Protein L32	Protein Coding	5
71	MRPL11	Mitochondrial Ribosomal Protein L11	Protein Coding	5
72	MRPL9	Mitochondrial Ribosomal Protein L9	Protein Coding	5
73	MRPL1	Mitochondrial Ribosomal Protein L1	Protein Coding	5
74	MRPL44	Mitochondrial Ribosomal Protein L44	Protein Coding	5
75	MRPS34	Mitochondrial Ribosomal Protein S34	Protein Coding	5
76	MRPL49	Mitochondrial Ribosomal Protein L49	Protein Coding	5
77	DAP3	Death Associated Protein 3	Protein Coding	5
78	MRPL57	Mitochondrial Ribosomal Protein L57	Protein Coding	5
79	MRPL24	Mitochondrial Ribosomal Protein L24	Protein Coding	5
80	MRPL43	Mitochondrial Ribosomal Protein L43	Protein Coding	5
81	GADD45GIP1	GADD45G Interacting Protein 1	Protein Coding	5
82	KGD4	Alpha-Ketoglutarate Dehydrogenase Subunit 4	Protein Coding	5
83	MRPL33	Mitochondrial Ribosomal Protein L33	Protein Coding	5
84	MRPL19	Mitochondrial Ribosomal Protein L19	Protein Coding	5
85	TSFM	Ts Translation Elongation Factor, Mitochondrial	Protein Coding	2
86	MALSU1	Mitochondrial Assembly Of Ribosomal Large Subunit 1	Protein Coding	2
87	MTFMT	Mitochondrial Methionyl-TRNA Formyltransferase	Protein Coding	2
88	MTIF3	Mitochondrial Translational Initiation Factor 3	Protein Coding	2
89	MT-ATP6	Mitochondrially Encoded ATP Synthase Membrane Subunit 6	Protein Coding	2
90	MT-ATP8	Mitochondrially Encoded ATP Synthase Membrane Subunit 8	Protein Coding	2
91	MT-CO1	Mitochondrially Encoded Cytochrome C Oxidase I	Protein Coding	2
92	MT-CO2	Mitochondrially Encoded Cytochrome C Oxidase II	Protein Coding	2
93	MT-CO3	Mitochondrially Encoded Cytochrome C Oxidase III	Protein Coding	2
94	MT-CYB	Mitochondrially Encoded Cytochrome B	Protein Coding	2
95	MTIF2	Mitochondrial Translational Initiation Factor 2	Protein Coding	2
96	MT-ND1	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 1	Protein Coding	2
97	MT-ND2	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 2	Protein Coding	2
98	MT-ND3	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 3	Protein Coding	2
99	MT-ND4	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 4	Protein Coding	2
100	MT-ND4L	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 4L	Protein Coding	2
101	MT-ND5	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 5	Protein Coding	2
102	MT-ND6	Mitochondrially Encoded NADH:Ubiquinone Oxidoreductase Core Subunit 6	Protein Coding	2
103	NDUFAB1	NADH:Ubiquinone Oxidoreductase Subunit AB1	Protein Coding	2
104	MTRES1	Mitochondrial Transcription Rescue Factor 1	Protein Coding	2
105	MIEF1	Mitochondrial Elongation Factor 1	Protein Coding	2
106	MTRF1L	Mitochondrial Translation Release Factor 1 Like	Protein Coding	2
107	TUFM	Tu Translation Elongation Factor, Mitochondrial	Protein Coding	2
108	GFM2	GTP Dependent Ribosome Recycling Factor Mitochondrial 2	Protein Coding	2
109	GFM1	G Elongation Factor Mitochondrial 1	Protein Coding	2
110	MTRFR	Mitochondrial Translation Release Factor In Rescue	Protein Coding	2
111	MRRF	Mitochondrial Ribosome Recycling Factor	Protein Coding	2
112	MTRF1	Mitochondrial Translation Release Factor 1	Protein Coding	2

Disorders associated with Mitochondrial translation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Mitochondrial complex v deficiency, mitochondrial type 1	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	16.00
2	Neuropathy, ataxia, and retinitis pigmentosa	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	16.00
3	Striatonigral degeneration, infantile, mitochondrial	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	16.00
4	Camptodactyly of fingers	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	16.00
5	Leigh syndrome, nuclear	Enrichment	MRPS34, MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6	16.00
6	Mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like episodes	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6	16.00
7	Leber hereditary optic neuropathy, modifier of	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6	16.00
8	Leigh syndrome, mitochondrial	Enrichment	MT-ATP6, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND5, MT-ND6	16.00
9	Leber plus disease	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6	16.00
10	Mitochondrial myopathy with reversible cytochrome c oxidase deficiency	Enrichment	MT-ATP6, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND5	16.00
11	Mitochondrial disease	Enrichment	GFM2, MRPL39, MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6, OXA1L	16.00
12	Hypertelorism	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	11.29
13	Leigh disease	Enrichment	MRPL39, MRPS34, MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5, MT-ND6	11.27
14	Mitochondrial myopathy, infantile, transient	Enrichment	MT-ATP6, MT-CO1, MT-CO2, MT-CO3, MT-CYB, MT-ND1, MT-ND2, MT-ND5	11.10
15	Leber optic atrophy and dystonia	Enrichment	MT-ND1, MT-ND3, MT-ND4, MT-ND5, MT-ND6	10.66
16	Retinitis pigmentosa	Enrichment	MT-ATP6, MT-ATP8, MT-CO1, MT-CO2, MT-CO3, MT-ND1, MT-ND2, MT-ND3, MT-ND4, MT-ND4L, MT-ND5	6.31
17	Familial colorectal cancer	Enrichment	MT-CO1, MT-CO2, MT-CYB, MT-ND4L	6.23
18	Cardiomyopathy, infantile histiocytoid	Enrichment	MT-ATP6, MT-ATP8, MT-CYB	5.80
19	Optic nerve disease	Enrichment	MT-ATP6, MT-ATP8, MT-ND1	4.33
20	Rare mitochondrial non-syndromic sensorineural deafness	Enrichment	MT-CO1, MT-ND1, MT-ND4	4.33
21	Cardiomyopathy, infantile hypertrophic	Enrichment	MT-ATP6, MT-ATP8	4.26
22	Alzheimer disease mitochondrial	Enrichment	MT-ND1, MT-ND2	4.26
23	Periodic paralysis with later-onset distal motor neuropathy	Enrichment	MT-ATP6, MT-ATP8	4.26
24	Combined oxidative phosphorylation deficiency 1	Enrichment	GFM1, MRPL44	3.92
25	Perrault syndrome 1	Enrichment	DAP3, ERAL1, MRPL49	3.87
26	Cox deficiency, benign infantile mitochondrial myopathy	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.86
27	Mitochondrial complex i deficiency, nuclear type 1	Enrichment	MT-ND1, MT-ND2, MT-ND3, MT-ND4	3.75
28	Hereditary recurrent myoglobinuria	Enrichment	MT-CO1, MT-CO3	3.49
29	Optic atrophy plus syndrome	Enrichment	MT-ND1, MT-ND4, MT-ND6, MTRFR	3.33
30	Mitochondrial complex iv deficiency, nuclear type 1	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.25
31	Deafness, nonsyndromic sensorineural, mitochondrial	Enrichment	MT-CO1, MT-ND1	3.09
32	Parkinson disease 6, autosomal recessive early-onset	Enrichment	MT-ND5, MT-ND6	3.09
33	Tetralogy of fallot	Enrichment	MT-CO1, MT-CO2, MT-CO3	3.04
34	Isolated atp synthase deficiency	Enrichment	MT-ATP6, MT-ATP8	2.83
35	Aortic valve disease 1	Enrichment	MT-ATP6, MT-ATP8	2.39
36	Combined oxidative phosphorylation deficiency 2	Enrichment	MRPS16	2.19
37	Combined oxidative phosphorylation deficiency 34	Enrichment	MRPS7	2.19
38	Combined oxidative phosphorylation deficiency 51	Enrichment	PTCD3	2.19
39	Combined oxidative phosphorylation deficiency 16	Enrichment	MRPL44	2.19
40	Combined oxidative phosphorylation deficiency 5	Enrichment	MRPS22	2.19
41	Combined oxidative phosphorylation deficiency 15	Enrichment	MTFMT	2.19
42	Combined oxidative phosphorylation deficiency 46	Enrichment	MRPS23	2.19
43	Mitochondrial complex i deficiency, nuclear type 27	Enrichment	MTFMT	2.19
44	Combined oxidative phosphorylation deficiency 38	Enrichment	MRPS14	2.19
45	Ovarian dysgenesis 7	Enrichment	MRPS22	2.19
46	Combined oxidative phosphorylation deficiency 45	Enrichment	MRPL12	2.19
47	Combined oxidative phosphorylation deficiency 50	Enrichment	MRPS25	2.19
48	Combined oxidative phosphorylation deficiency 59	Enrichment	MRPL39	2.19
49	Perrault syndrome 7	Enrichment	DAP3	2.19
50	Combined oxidative phosphorylation deficiency 60	Enrichment	MRPL49	2.19
51	Combined oxidative phosphorylation deficiency 4	Enrichment	TUFM	2.19
52	Combined oxidative phosphorylation deficiency 3	Enrichment	TSFM	2.19
53	Spastic paraplegia 55, autosomal recessive	Enrichment	MTRFR	2.18
54	Combined oxidative phosphorylation deficiency 7	Enrichment	MTRFR	2.18
55	Optic atrophy 14	Enrichment	MIEF1	2.18
56	Ataxia and polyneuropathy, adult-onset	Enrichment	MT-ATP6	2.13
57	Mitochondrial complex i deficiency, mitochondrial type 1	Enrichment	MT-ND3	2.13
58	Myoglobinuria, recurrent	Enrichment	MT-CO1	2.13
59	Myopathy, lactic acidosis, and sideroblastic anemia 3	Enrichment	MT-ATP6	2.13
60	Oncocytoma	Enrichment	MT-ND6	2.13
61	Combined oxidative phosphorylation deficiency 39	Enrichment	GFM2	2.13
62	Autosomal dominant spastic ataxia	Enrichment	MT-CO3	2.13
63	Maternally-inherited spastic paraplegia	Enrichment	MT-ATP6	2.13
64	Wilms tumor 2	Enrichment	MRPL23	1.89
65	Grange syndrome	Enrichment	DAP3	1.89
66	Waardenburg syndrome, type 2f	Enrichment	MTFMT	1.89
67	Combined oxidative phosphorylation deficiency 36	Enrichment	MRPS2	1.89
68	Combined oxidative phosphorylation deficiency 47	Enrichment	MRPS28	1.89
69	Perrault syndrome 6	Enrichment	ERAL1	1.89
70	Combined oxidative phosphorylation deficiency 9	Enrichment	MRPL3	1.89
71	Charcot-marie-tooth disease, demyelinating, type 1a	Enrichment	MT-ATP6	1.83
72	Deafness, sensorineural, autosomal-mitochondrial type	Enrichment	MT-ND1	1.83
73	Charcot-marie-tooth disease type 1a	Enrichment	MT-ATP6	1.83
74	Combined oxidative phosphorylation deficiency	Enrichment	GFM1	1.72
75	Neuropathy, hereditary motor and sensory, type via, with optic atrophy	Enrichment	MTRFR	1.71
76	Keratoderma, palmoplantar, with deafness	Enrichment	MT-CO1	1.65
77	Mitochondrial myopathy, episodic, with or without optic atrophy and reversible leukoencephalopathy	Enrichment	MT-ND3	1.65
78	Mitochondrial complex v deficiency, nuclear type 5	Enrichment	MT-ND5	1.65
79	Gonadal dysgenesis	Enrichment	MT-ATP6	1.65
80	Myelodysplastic syndrome with ring sideroblasts	Enrichment	MT-CO1	1.65
81	Combined oxidative phosphorylation deficiency 32	Enrichment	MRPS34	1.59
82	Dystonia	Enrichment	MT-ND1, MT-ND6	1.56
83	Familial infantile bilateral striatal necrosis	Enrichment	MT-ATP6	1.53
84	Mitochondrial oxidative phosphorylation disorder	Enrichment	MTFMT	1.50
85	Epilepsy	Enrichment	MT-CO3, MT-CYB	1.45
86	Kearns-sayre syndrome	Enrichment	MT-ATP8	1.44
87	Parkinsonism	Enrichment	MT-ND6	1.29
88	Perrault syndrome 2	Enrichment	ERAL1	1.25
89	Mitochondrial encephalomyopathy	Enrichment	MT-CYB	1.14
90	46 xx gonadal dysgenesis	Enrichment	MRPS22	1.13
91	Migraine with or without aura 1	Enrichment	MT-ND1	1.10
92	Isolated complex iii deficiency	Enrichment	MT-CYB	1.10
93	Premature menopause	Enrichment	MRPS7	1.10
94	Myoclonic epilepsy associated with ragged-red fibers	Enrichment	MT-ND5	1.07
95	Restrictive cardiomyopathy	Enrichment	MT-ND1	1.07
96	Alzheimer's disease	Enrichment	MT-ND1	1.03
97	Beckwith-wiedemann syndrome	Enrichment	MRPL23	0.96
98	Hydrocephalus, congenital, 1	Enrichment	MT-ND1	0.95
99	Alzheimer disease, familial, 1	Enrichment	MT-ND1	0.92
100	Sudden infant death syndrome	Enrichment	MT-ND1	0.92
101	Parkinson's disease	Enrichment	MT-ND1	0.88
102	Colorectal cancer	Enrichment	MT-CO1, MT-ND1	0.86
103	Attention deficit-hyperactivity disorder	Enrichment	MT-ND1	0.82
104	Parkinson disease, late-onset	Enrichment	MT-ND1	0.78
105	Auditory neuropathy	Enrichment	MT-ND6	0.75
106	Charcot-marie-tooth disease	Enrichment	MT-ATP6	0.58
107	Sensorineural hearing loss	Enrichment	MRPS7	0.57
108	Hereditary breast carcinoma	Enrichment	MT-CYB	0.55
109	Body mass index quantitative trait locus 11	Enrichment	MT-CYB	0.51
110	Primary ovarian insufficiency	Enrichment	MRPS7	0.50
111	Dilated cardiomyopathy	Enrichment	TSFM	0.39
112	Breast cancer	Enrichment	MT-CYB	0.37
113	Rare genetic deafness	Enrichment	MT-ND1	0.35
114	Ovarian cancer	Enrichment	MT-CYB	0.27
115	Hereditary retinal dystrophy	Enrichment	MT-ND4, MT-ND6	0.19
116	Fundus dystrophy	Enrichment	MT-ND4, MT-ND6	0.19

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Mitochondrial translation

Pathway Network for Mitochondrial translation

Pathway network for the Mitochondrial translation SuperPath

Member Pathways for Mitochondrial translation

Pathways in the Mitochondrial translation SuperPath

Gene overlap in member pathways for Mitochondrial translation SuperPath

Associated Genes for Mitochondrial translation

Associated Disorders for Mitochondrial translation

Disorders associated with Mitochondrial translation SuperPath

STRING Interaction Network for Mitochondrial translation

Sources for Mitochondrial translation