MNAR-PELP1 and Estrogen Receptor Interaction

No Pathway Network information available for MNAR-PELP1 and Estrogen Receptor Interaction

Pathways in the MNAR-PELP1 and Estrogen Receptor Interaction SuperPath

#	Name	Source	Genes
1	MNAR-PELP1 and Estrogen Receptor Interaction	QIAGEN	CCND1 E2F1 E2F2 E2F3 E2F4 E2F5 ELK1 ESR1 ESR2 FOS HRAS JUN KRAS MAPK1 MAPK3 MRAS NRAS PELP1 RB1 RRAS RRAS2 SRC TFDP1 (see all 23) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	CCND1	Cyclin D1	Protein Coding	1
2	E2F1	E2F Transcription Factor 1	Protein Coding	1
3	E2F2	E2F Transcription Factor 2	Protein Coding	1
4	E2F3	E2F Transcription Factor 3	Protein Coding	1
5	E2F4	E2F Transcription Factor 4	Protein Coding	1
6	E2F5	E2F Transcription Factor 5	Protein Coding	1
7	ELK1	ETS Transcription Factor ELK1	Protein Coding	1
8	ESR1	Estrogen Receptor 1	Protein Coding	1
9	ESR2	Estrogen Receptor 2	Protein Coding	1
10	FOS	Fos Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
11	HRAS	HRas Proto-Oncogene, GTPase	Protein Coding	1
12	JUN	Jun Proto-Oncogene, AP-1 Transcription Factor Subunit	Protein Coding	1
13	KRAS	KRAS Proto-Oncogene, GTPase	Protein Coding	1
14	MAPK1	Mitogen-Activated Protein Kinase 1	Protein Coding	1
15	MAPK3	Mitogen-Activated Protein Kinase 3	Protein Coding	1
16	MRAS	Muscle RAS Oncogene Homolog	Protein Coding	1
17	NRAS	NRAS Proto-Oncogene, GTPase	Protein Coding	1
18	PELP1	Proline, Glutamate And Leucine Rich Protein 1	Protein Coding	1
19	RB1	RB Transcriptional Corepressor 1	Protein Coding	1
20	RRAS	RAS Related	Protein Coding	1
21	RRAS2	RAS Related 2	Protein Coding	1
22	SRC	SRC Proto-Oncogene, Non-Receptor Tyrosine Kinase	Protein Coding	1
23	TFDP1	Transcription Factor Dp-1	Protein Coding	1

Disorders associated with MNAR-PELP1 and Estrogen Receptor Interaction SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Noonan syndrome 1	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS, RRAS2	10.43
2	Rasopathy	Enrichment	HRAS, KRAS, MRAS, NRAS, RRAS2	9.25
3	Schimmelpenning-feuerstein-mims syndrome	Enrichment	HRAS, KRAS, NRAS	7.77
4	Nevus, epidermal	Enrichment	HRAS, KRAS, NRAS	6.83
5	Lung non-small cell carcinoma	Enrichment	HRAS, KRAS, NRAS	6.16
6	Juvenile myelomonocytic leukemia	Enrichment	KRAS, NRAS, RRAS	6.03
7	Noonan syndrome and noonan-related syndrome	Enrichment	HRAS, KRAS, NRAS	5.72
8	Ras-associated autoimmune leukoproliferative disorder	Enrichment	KRAS, NRAS	5.56
9	Large congenital melanocytic nevus	Enrichment	HRAS, NRAS	5.08
10	Bladder cancer	Enrichment	HRAS, KRAS, RB1	4.82
11	Differentiated thyroid carcinoma	Enrichment	HRAS, KRAS, NRAS	4.82
12	Chronic myelogenous leukemia, bcr-abl1 positive	Enrichment	KRAS, NRAS	4.78
13	Thyroid cancer, nonmedullary, 2	Enrichment	HRAS, NRAS	4.24
14	Leukemia, chronic myeloid	Enrichment	KRAS, NRAS	4.24
15	Noonan syndrome 3	Enrichment	HRAS, KRAS	4.24
16	Follicular thyroid carcinoma	Enrichment	HRAS, NRAS	4.24
17	Melanocytic nevus syndrome, congenital	Enrichment	HRAS, NRAS	4.12
18	Lip and oral cavity carcinoma	Enrichment	HRAS, RB1	3.75
19	Lung cancer susceptibility 3	Enrichment	KRAS, RB1	3.61
20	Breast cancer	Enrichment	ESR1, JUN, KRAS	3.58
21	Colorectal cancer	Enrichment	CCND1, NRAS, SRC	3.39
22	Ovarian cancer	Enrichment	KRAS, RB1, RRAS2	3.20
23	Non-immune hydrops fetalis	Enrichment	HRAS, KRAS	2.91
24	Oculoectodermal syndrome	Enrichment	KRAS	2.77
25	Melanosis, neurocutaneous	Enrichment	NRAS	2.77
26	Noonan syndrome 6	Enrichment	NRAS	2.77
27	Noonan syndrome 11	Enrichment	MRAS	2.77
28	Noonan syndrome 13	Enrichment	MAPK1	2.77
29	Cardiofaciocutaneous syndrome 2	Enrichment	KRAS	2.77
30	Ovarian dysgenesis 8	Enrichment	ESR2	2.77
31	Thrombocytopenia 6	Enrichment	SRC	2.77
32	Trilateral retinoblastoma	Enrichment	RB1	2.77
33	Congenital pulmonary airway malformation	Enrichment	KRAS	2.77
34	Phakomatosis pigmentokeratotica	Enrichment	HRAS	2.77
35	Neurocutaneous melanocytosis	Enrichment	NRAS	2.77
36	Lung oat cell carcinoma	Enrichment	RB1	2.77
37	Leukemia, acute myeloid	Enrichment	KRAS, NRAS	2.69
38	Hereditary breast carcinoma	Enrichment	ESR1, KRAS	2.60
39	Costello syndrome	Enrichment	HRAS	2.47
40	Encephalocraniocutaneous lipomatosis	Enrichment	KRAS	2.47
41	Chromosome 13q14 deletion syndrome	Enrichment	RB1	2.47
42	Noonan syndrome 12	Enrichment	RRAS2	2.47
43	Familial retinoblastoma	Enrichment	RB1	2.47
44	Wooly hair nevus	Enrichment	HRAS	2.47
45	Myeloma, multiple	Enrichment	CCND1, KRAS	2.40
46	Retinoblastoma	Enrichment	RB1	2.29
47	Thyroid carcinoma, familial medullary	Enrichment	ESR2	2.29
48	Langerhans cell histiocytosis	Enrichment	NRAS	2.29
49	Osteogenic sarcoma	Enrichment	RB1	2.29
50	Estrogen resistance	Enrichment	ESR1	2.29
51	Woolly hair, autosomal recessive 3	Enrichment	RB1	2.29
52	Hypotrichosis 8	Enrichment	RB1	2.29
53	Squamous cell carcinoma	Enrichment	RB1	2.29
54	Migraine without aura	Enrichment	ESR1	2.29
55	Bone osteosarcoma	Enrichment	RB1	2.29
56	Spermatocytoma	Enrichment	HRAS	2.29
57	Cardiofaciocutaneous syndrome 1	Enrichment	KRAS	2.17
58	Diffuse gastric and lobular breast cancer syndrome	Enrichment	KRAS	2.17
59	Small cell cancer of the lung	Enrichment	RB1	2.17
60	Chromosome 22q11.2 deletion syndrome, distal	Enrichment	MAPK1	2.17
61	Lynch syndrome 4	Enrichment	RB1	2.17
62	Congenital generalized lipodystrophy	Enrichment	FOS	2.17
63	Mantle cell lymphoma	Enrichment	CCND1	2.17
64	Arthrogryposis multiplex congenita 3, myogenic type	Enrichment	ESR1	2.17
65	Cardiofaciocutaneous syndrome	Enrichment	KRAS	2.17
66	Lung sarcomatoid carcinoma	Enrichment	KRAS	2.17
67	Pilocytic astrocytoma	Enrichment	KRAS	2.17
68	Epidermolytic nevus	Enrichment	HRAS	2.17
69	Von hippel-lindau syndrome	Enrichment	CCND1	2.07
70	Histiocytoid hemangioma	Enrichment	FOS	2.07
71	Breast adenocarcinoma	Enrichment	KRAS	1.99
72	Lung squamous cell carcinoma	Enrichment	KRAS	1.99
73	Myelofibrosis	Enrichment	SRC	1.93
74	Capillary malformation-arteriovenous malformation 1	Enrichment	KRAS	1.93
75	Gallbladder cancer	Enrichment	KRAS	1.93
76	Pilomyxoid astrocytoma	Enrichment	KRAS	1.93
77	Arteriovenous malformation	Enrichment	HRAS	1.82
78	Leukemia, chronic lymphocytic	Enrichment	CCND1	1.77
79	Myopathy, x-linked, with excessive autophagy	Enrichment	HRAS	1.77
80	Migraine with or without aura 1	Enrichment	ESR1	1.73
81	Specific learning disability	Enrichment	MAPK1	1.73
82	Protein-deficiency anemia	Enrichment	NRAS	1.66
83	Osteoporosis	Enrichment	SRC	1.63
84	Lynch syndrome	Enrichment	KRAS	1.60
85	Rhabdomyosarcoma	Enrichment	HRAS	1.57
86	Heart, malformation of	Enrichment	MAPK1	1.52
87	Arteriovenous malformations of the brain	Enrichment	KRAS	1.50
88	Myocardial infarction	Enrichment	ESR1	1.44
89	Pancreatic cancer	Enrichment	KRAS	1.38
90	Hydrops fetalis, nonimmune	Enrichment	HRAS	1.36
91	Lung cancer	Enrichment	KRAS	1.28
92	Gastric cancer	Enrichment	KRAS	1.15
93	Thrombocytopenia	Enrichment	SRC	1.11
94	Hereditary breast ovarian cancer syndrome	Enrichment	KRAS	1.05
95	Microcephaly	Enrichment	MAPK1	0.72
96	Inherited cancer-predisposing syndrome	Enrichment	RB1	0.70

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

MNAR-PELP1 and Estrogen Receptor Interaction

Pathway Network for MNAR-PELP1 and Estrogen Receptor Interaction

Member Pathways for MNAR-PELP1 and Estrogen Receptor Interaction

Pathways in the MNAR-PELP1 and Estrogen Receptor Interaction SuperPath

Associated Genes for MNAR-PELP1 and Estrogen Receptor Interaction

Associated Disorders for MNAR-PELP1 and Estrogen Receptor Interaction

Disorders associated with MNAR-PELP1 and Estrogen Receptor Interaction SuperPath

STRING Interaction Network for MNAR-PELP1 and Estrogen Receptor Interaction

Sources for MNAR-PELP1 and Estrogen Receptor Interaction