Modulators of TCR signaling and T cell activation

No Pathway Network information available for Modulators of TCR signaling and T cell activation

Pathways in the Modulators of TCR signaling and T cell activation SuperPath

#	Name	Source	Genes
1	Modulators of TCR signaling and T cell activation	WikiPathways	AGO1 ARIH2 CD5 CDKN1B CUL5 DGKA DGKZ ELOB FIBP GNA13 MEF2D NDUFB10 PCBP2 PTPN6 RASA2 RHOH RNF7 RPRD1B SH2D1A SMARCB1 SOCS1 TMEM222 TNFAIP3 UBASH3A ZFP36L1 (see all 25) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	DGKA	Diacylglycerol Kinase Alpha	Protein Coding	1
2	CD5	CD5 Molecule	Protein Coding	1
3	FIBP	FGF1 Intracellular Binding Protein	Protein Coding	1
4	SOCS1	Suppressor Of Cytokine Signaling 1	Protein Coding	1
5	DGKZ	Diacylglycerol Kinase Zeta	Protein Coding	1
6	CUL5	Cullin 5	Protein Coding	1
7	TNFAIP3	TNF Alpha Induced Protein 3	Protein Coding	1
8	SMARCB1	SWI/SNF Related BAF Chromatin Remodeling Complex Subunit B1	Protein Coding	1
9	RASA2	RAS P21 Protein Activator 2	Protein Coding	1
10	PTPN6	Protein Tyrosine Phosphatase Non-Receptor Type 6	Protein Coding	1
11	UBASH3A	Ubiquitin Associated And SH3 Domain Containing A	Protein Coding	1
12	MEF2D	Myocyte Enhancer Factor 2D	Protein Coding	1
13	SH2D1A	SH2 Domain Containing 1A	Protein Coding	1
14	AGO1	Argonaute RISC Component 1	Protein Coding	1
15	GNA13	G Protein Subunit Alpha 13	Protein Coding	1
16	CDKN1B	Cyclin Dependent Kinase Inhibitor 1B	Protein Coding	1
17	TMEM222	Transmembrane Protein 222	Protein Coding	1
18	ARIH2	Ariadne RBR E3 Ubiquitin Protein Ligase 2	Protein Coding	1
19	ELOB	Elongin B	Protein Coding	1
20	ZFP36L1	ZFP36 Ring Finger Protein Like 1	Protein Coding	1
21	RPRD1B	Regulation Of Nuclear Pre-MRNA Domain Containing 1B	Protein Coding	1
22	PCBP2	Poly(RC) Binding Protein 2	Protein Coding	1
23	NDUFB10	NADH:Ubiquinone Oxidoreductase Subunit B10	Protein Coding	1
24	RHOH	Ras Homolog Family Member H	Protein Coding	1
25	RNF7	Ring Finger Protein 7	Protein Coding	1

Disorders associated with Modulators of TCR signaling and T cell activation SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Neurodevelopmental disorder with motor and speech delay and behavioral abnormalities	Enrichment	TMEM222	2.73
2	Lymphoproliferative syndrome, x-linked, 1	Enrichment	SH2D1A	2.73
3	Rhabdoid tumor predisposition syndrome 1	Enrichment	SMARCB1	2.73
4	Neuroendocrine tumor	Enrichment	CDKN1B	2.73
5	Neurilemmoma	Enrichment	SMARCB1	2.73
6	Coffin-siris syndrome 3	Enrichment	SMARCB1	2.73
7	Thauvin-robinet-faivre syndrome	Enrichment	FIBP	2.73
8	Immunodeficiency 129	Enrichment	RHOH	2.73
9	Learning disability	Enrichment	FIBP	2.73
10	Familial behcet-like autoinflammatory syndrome	Enrichment	TNFAIP3	2.73
11	T-cell immunodeficiency with epidermodysplasia verruciformis	Enrichment	RHOH	2.73
12	Vegetative pyoderma gangrenosum	Enrichment	PTPN6	2.73
13	Bullous pyoderma gangrenosum	Enrichment	PTPN6	2.73
14	Pustular pyoderma gangrenosum	Enrichment	PTPN6	2.73
15	Classic pyoderma gangrenosum	Enrichment	PTPN6	2.73
16	Systemic lupus erythematosus	Enrichment	SOCS1, TNFAIP3	2.63
17	Schwannomatosis 1	Enrichment	SMARCB1	2.43
18	Autoinflammatory syndrome, familial, behcet-like 1	Enrichment	TNFAIP3	2.43
19	Multiple endocrine neoplasia, type iv	Enrichment	CDKN1B	2.43
20	Neurodevelopmental disorder with language delay and behavioral abnormalities, with or without seizures	Enrichment	AGO1	2.43
21	Rhabdoid tumor predisposition syndrome	Enrichment	SMARCB1	2.43
22	Lymphoproliferative syndrome	Enrichment	SH2D1A	2.43
23	Immune thrombocytopenia	Enrichment	SOCS1	2.26
24	Neutrophilic dermatosis, acute febrile	Enrichment	PTPN6	2.26
25	Autoinflammatory syndrome, familial, with or without immunodeficiency	Enrichment	SOCS1	2.26
26	Atypical teratoid rhabdoid tumor	Enrichment	SMARCB1	2.26
27	Mitochondrial complex i deficiency, nuclear type 35	Enrichment	NDUFB10	2.26
28	Schwannomatosis	Enrichment	SMARCB1	2.26
29	Anemia, autoimmune hemolytic	Enrichment	SOCS1	2.13
30	Primary hyperparathyroidism	Enrichment	CDKN1B	2.13
31	Full schwannomatosis	Enrichment	SMARCB1	2.13
32	Multiple endocrine neoplasia, type i	Enrichment	CDKN1B	1.89
33	Overgrowth syndrome	Enrichment	FIBP	1.89
34	Ovarian cancer	Enrichment	CDKN1B, SMARCB1	1.83
35	Autism spectrum disorder	Enrichment	ARIH2, SMARCB1	1.77
36	Meningioma, familial	Enrichment	SMARCB1	1.70
37	Complex neurodevelopmental disorder	Enrichment	AGO1, TMEM222	1.66
38	Meningioma	Enrichment	SMARCB1	1.66
39	Microphthalmia/coloboma 12	Enrichment	FIBP	1.63
40	Nk-cell enteropathy	Enrichment	SMARCB1	1.63
41	Inherited cancer-predisposing syndrome	Enrichment	CDKN1B, SMARCB1	1.61
42	Coloboma of macula	Enrichment	FIBP	1.56
43	Coffin-siris syndrome 1	Enrichment	SMARCB1	1.56
44	Diffuse large b-cell lymphoma	Enrichment	SOCS1	1.46
45	Noonan syndrome 1	Enrichment	RASA2	1.38
46	Autoinflammatory disease	Enrichment	SH2D1A	1.36
47	Mitochondrial complex i deficiency, nuclear type 1	Enrichment	NDUFB10	1.17

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Modulators of TCR signaling and T cell activation

Pathway Network for Modulators of TCR signaling and T cell activation

Member Pathways for Modulators of TCR signaling and T cell activation

Pathways in the Modulators of TCR signaling and T cell activation SuperPath

Associated Genes for Modulators of TCR signaling and T cell activation

Associated Disorders for Modulators of TCR signaling and T cell activation

Disorders associated with Modulators of TCR signaling and T cell activation SuperPath

STRING Interaction Network for Modulators of TCR signaling and T cell activation

Sources for Modulators of TCR signaling and T cell activation