Monoamine transport

No Pathway Network information available for Monoamine transport

Pathways in the Monoamine transport SuperPath

#	Name	Source	Genes
1	Monoamine transport	WikiPathways	ACHE ADORA2A AGT AMPH CDC25C DBH FBXO32 HRH3 IL1B IL1R1 ITGB3 MAPK14 NECTIN2 NOS1 PPP2CB RBL2 SCAMP2 SLC5A7 SLC6A1 SLC6A2 SLC6A3 SLC6A4 STX1A SYN1 TDO2 TGFB1I1 TH TNF TNFRSF11B TPH2 TSC2 UNC13B (see all 32) (see less)
2	Serotonin transporter activity	WikiPathways	IL1B IL1R1 ITGB3 MAOA NOS1 PPP2CB SCAMP2 SLC6A4 STX1A TGFB1I1 TPH2 (see all 11) (see less)

Ordered by rank within the SuperPath, via the multiplicity of each gene in the constituent pathways

#	Symbol	Description	Category	# Related Pathways
1	STX1A	Syntaxin 1A	Protein Coding	2
2	SLC6A4	Solute Carrier Family 6 Member 4	Protein Coding	2
3	NOS1	Nitric Oxide Synthase 1	Protein Coding	2
4	ITGB3	Integrin Subunit Beta 3	Protein Coding	2
5	IL1R1	Interleukin 1 Receptor Type 1	Protein Coding	2
6	IL1B	Interleukin 1 Beta	Protein Coding	2
7	TPH2	Tryptophan Hydroxylase 2	Protein Coding	2
8	TGFB1I1	Transforming Growth Factor Beta 1 Induced Transcript 1	Protein Coding	2
9	PPP2CB	Protein Phosphatase 2 Catalytic Subunit Beta	Protein Coding	2
10	SCAMP2	Secretory Carrier Membrane Protein 2	Protein Coding	2
11	CDC25C	Cell Division Cycle 25C	Protein Coding	1
12	TSC2	TSC Complex Subunit 2	Protein Coding	1
13	TNF	Tumor Necrosis Factor	Protein Coding	1
14	TH	Tyrosine Hydroxylase	Protein Coding	1
15	TDO2	Tryptophan 2,3-Dioxygenase	Protein Coding	1
16	SYN1	Synapsin I	Protein Coding	1
17	SLC6A3	Solute Carrier Family 6 Member 3	Protein Coding	1
18	SLC6A2	Solute Carrier Family 6 Member 2	Protein Coding	1
19	SLC6A1	Solute Carrier Family 6 Member 1	Protein Coding	1
20	SLC5A7	Solute Carrier Family 5 Member 7	Protein Coding	1
21	RBL2	RB Transcriptional Corepressor Like 2	Protein Coding	1
22	NECTIN2	Nectin Cell Adhesion Molecule 2	Protein Coding	1
23	TNFRSF11B	TNF Receptor Superfamily Member 11b	Protein Coding	1
24	ACHE	Acetylcholinesterase (Yt Blood Group)	Protein Coding	1
25	AGT	Angiotensinogen	Protein Coding	1
26	DBH	Dopamine Beta-Hydroxylase	Protein Coding	1
27	MAPK14	Mitogen-Activated Protein Kinase 14	Protein Coding	1
28	ADORA2A	Adenosine A2a Receptor	Protein Coding	1
29	FBXO32	F-Box Protein 32	Protein Coding	1
30	HRH3	Histamine Receptor H3	Protein Coding	1
31	UNC13B	Unc-13 Homolog B	Protein Coding	1
32	AMPH	Amphiphysin	Protein Coding	1
33	MAOA	Monoamine Oxidase A	Protein Coding	1

Disorders associated with Monoamine transport SuperPath

according to GeneCards Suite gene sharing

#	Disorder	Type	Genes	Score
1	Pyloric stenosis, infantile hypertrophic, 1	Enrichment	NOS1	3.09
2	Brunner syndrome	Enrichment	MAOA	3.09
3	Chronic recurrent multifocal osteomyelitis 3	Enrichment	IL1R1	3.09
4	Major affective disorder 1	Enrichment	TPH2	2.79
5	Obsessive-compulsive disorder	Enrichment	SLC6A4	2.79
6	Neuronopathy, distal hereditary motor, autosomal dominant 7	Enrichment	SLC5A7	2.63
7	Yt blood group antigen	Enrichment	ACHE	2.63
8	Intellectual developmental disorder, x-linked 50	Enrichment	SYN1	2.63
9	Brunet-wagner neurodevelopmental syndrome	Enrichment	RBL2	2.63
10	Epilepsy, x-linked 1, with variable learning disabilities and behavior disorders	Enrichment	SYN1	2.63
11	Hypertryptophanemia	Enrichment	TDO2	2.63
12	X-linked epilepsy with variable learning disabilities and behavior disorders	Enrichment	SYN1	2.63
13	Parkinsonism-dystonia 1, infantile-onset	Enrichment	SLC6A3	2.63
14	Postural orthostatic tachycardia syndrome	Enrichment	SLC6A2	2.63
15	Classic dopamine transporter deficiency syndrome	Enrichment	SLC6A3	2.63
16	Acute encephalopathy with biphasic seizures and late reduced diffusion	Enrichment	ADORA2A	2.63
17	Parkinsonism-dystonia, infantile	Enrichment	SLC6A3	2.63
18	Hyper-ige syndrome 1, autosomal dominant, with recurrent infections	Enrichment	ITGB3	2.61
19	Bleeding disorder, platelet-type, 16	Enrichment	ITGB3	2.61
20	Bleeding disorder, platelet-type, 24	Enrichment	ITGB3	2.61
21	Idiopathic achalasia	Enrichment	NOS1	2.49
22	Major depressive disorder	Enrichment	TPH2	2.39
23	Glanzmann thrombasthenia 2	Enrichment	ITGB3	2.39
24	Paget disease of bone 5, juvenile-onset	Enrichment	TNFRSF11B	2.33
25	Lymphangioleiomyomatosis	Enrichment	TSC2	2.33
26	Segawa syndrome, autosomal recessive	Enrichment	TH	2.33
27	Orthostatic hypotension 1	Enrichment	DBH	2.33
28	Immunodeficiency 127	Enrichment	TNF	2.33
29	Myasthenic syndrome, congenital, 20, presynaptic	Enrichment	SLC5A7	2.33
30	Dopamine beta-hydroxylase deficiency	Enrichment	DBH	2.33
31	Slc6a1-related neurodevelopmental disorder	Enrichment	SLC6A1	2.33
32	Distal hereditary motor neuropathy type 7	Enrichment	SLC5A7	2.33
33	Anxiety	Enrichment	SLC6A4	2.31
34	Fetomaternal alloimmune thrombocytopenia 1	Enrichment	ITGB3	2.31
35	Glanzmann thrombasthenia 1	Enrichment	ITGB3	2.25
36	Dystonia, dopa-responsive	Enrichment	TH	2.15
37	Tuberous sclerosis 1	Enrichment	TSC2	2.15
38	Polycystic kidney disease, infantile severe, with tuberous sclerosis	Enrichment	TSC2	2.15
39	Psoriatic arthritis	Enrichment	TNF	2.15
40	Tuberous sclerosis 2	Enrichment	TSC2	2.15
41	Hamartoma	Enrichment	TSC2	2.15
42	Xanthinuria, type ii	Enrichment	TSC2	2.15
43	Migraine without aura	Enrichment	TNF	2.15
44	Developmental and epileptic encephalopathy 94	Enrichment	SLC6A1	2.15
45	Autosomal dominant macrothrombocytopenia	Enrichment	ITGB3	2.09
46	Focal cortical dysplasia, type ii	Enrichment	TSC2	2.03
47	Chondrocalcinosis 2	Enrichment	TNFRSF11B	2.03
48	Tobacco addiction	Enrichment	SLC6A3	2.03
49	Tuberous sclerosis	Enrichment	TSC2	2.03
50	Cerebral malaria	Enrichment	TNF	2.03
51	Isolated focal cortical dysplasia type ii	Enrichment	TSC2	2.03
52	Vascular dementia	Enrichment	TNF	1.93
53	Renal tubular dysgenesis	Enrichment	AGT	1.85
54	Williams-beuren syndrome	Enrichment	STX1A	1.79
55	Polycystic kidney disease 1 with or without polycystic liver disease	Enrichment	TSC2	1.79
56	Polycystic kidney disease 1	Enrichment	TSC2	1.79
57	Myocardial infarction	Enrichment	ITGB3	1.75
58	Orthostatic intolerance	Enrichment	SLC6A2	1.73
59	Myoclonic-atonic epilepsy	Enrichment	SLC6A1	1.68
60	Adult hepatocellular carcinoma	Enrichment	TSC2	1.68
61	Asthma	Enrichment	TNF	1.59
62	Presynaptic congenital myasthenic syndromes	Enrichment	SLC5A7	1.59
63	Cystic fibrosis	Enrichment	STX1A	1.59
64	Alzheimer's disease	Enrichment	TNF	1.52
65	Gastric cancer	Enrichment	IL1B	1.46
66	Autosomal dominant polycystic kidney disease	Enrichment	TSC2	1.46
67	Thrombocytopenia	Enrichment	ITGB3	1.42
68	Hypertension, essential	Enrichment	AGT	1.40
69	Neuropathy, hereditary motor and sensory, okinawa type	Enrichment	SLC5A7	1.36
70	Malaria	Enrichment	TNF	1.28
71	Autism	Enrichment	STX1A	1.25
72	Dystonia	Enrichment	TH	1.10
73	Systemic lupus erythematosus	Enrichment	TNF	1.05
74	Epilepsy	Enrichment	SYN1	1.04
75	Benign epilepsy with centrotemporal spikes	Enrichment	SLC6A1	1.03
76	Centralopathic epilepsy	Enrichment	SLC6A1	1.01
77	West syndrome	Enrichment	TSC2	1.01
78	Autosomal dominant non-syndromic intellectual disability	Enrichment	SLC6A1	0.95
79	Ovarian cancer	Enrichment	TSC2	0.67
80	Congenital nervous system abnormality	Enrichment	TSC2	0.65
81	Nervous system disease	Enrichment	TSC2	0.65
82	Autism spectrum disorder	Enrichment	TSC2	0.64
83	Inherited cancer-predisposing syndrome	Enrichment	TSC2	0.57

¹ WikiPathways

² PubChem

³ R&D Systems

⁴ Reactome

⁵ GeneGo (Thomson Reuters)

⁶ QIAGEN

⁷ PharmGKB

⁸ Cell Signaling Technology

⁹ Sino Biological

¹⁰ Tocris

¹¹ MalaCards

Monoamine transport

Pathway Network for Monoamine transport

Member Pathways for Monoamine transport

Pathways in the Monoamine transport SuperPath

Associated Genes for Monoamine transport

Associated Disorders for Monoamine transport

Disorders associated with Monoamine transport SuperPath

STRING Interaction Network for Monoamine transport

Sources for Monoamine transport